220 research outputs found

    Mobile phone usage in patients with type II diabetes and their intention to use it for self-management: A cross-sectional study in Iran

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    Background: Mobile health has potential for promotion of self-management in patients with chronic diseases. This study was conducted to investigate smartphone usage in patients with type II diabetes and their intention to use it for self-management. Methods: This cross-sectional study was conducted in 2018 with 176 patients with type II diabetes visiting a specialized diabetes clinic or one of two endocrinology and metabolism specialists in north of Iran. Data were collected using a validated questionnaire containing items on demographic characteristics, disease information, use of mobile phones, smartphones and the internet, and intention to use mobile phones for diabetes self-management. Results: The majority of the participants had mobile phones (94.9), smartphones (61.1), and daily access to the internet (81.3), and used phones two hours per day on average (80.1). They mostly used mobile phones to contact friends (89.2) and search for information (50.6), and their greatest intention for using smartphones and the internet for self-management was related to dietary planning (96), checking blood glucose (90.9), and contacting specialists (87.5). Younger participants were more interested in using smartphone applications (apps) (P < 0.001). About half of the participants argued that using apps can be interesting (54) and useful (50) for diabetes management, and intended to use apps much more in future (48.3). Conclusions: The majority of patients with type II diabetes are inclined to use mobile phone and the Internet, especially to plan their diet, check blood glucose, and contact their doctors. The present study provides valuable information for designing and implementing interventions based on mHealth to promote self-management in type II diabetes. © 2020 The Author(s)

    Behavioral feasibility of the clinical nursing information system

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    Background: Analysis of humanitarian issues affecting the implementation time of information systems to increase the acceptance of these systems is essential. Objective: The aim of this study was to assess the behavioral feasibility of the clinical nursing information system. Methods: An applied cross-sectional study was conducted with 348 nurses in 2015. Data were collected by face to face interviews and a questionnaire containing 33 questions, which were rated on a 5-point Likert scale. Face and content validity of the questionnaire was confirmed, and its reliability was estimated 0.90 through Cronbach's alpha coefficient. Data were analyzed using chi-square tests and t-test. Results: An average score of behavioral feasibility was 67.44. The rate of supply provided for implementing the clinical nursing information system was 55.2, which was in a semi-favorable level. The necessity of system deployment in the clinical nursing sector had the highest frequency (88.2) and interference of redesigning structures with the current work had the lowest frequency (43.6). Conclusion: The possibility of implementation of the clinical nursing information system in a behavioral dimension is at a semi-favorable level. To increase the acceptance of the system, presenting a new system as a positive change and further training of the nurses is recommended. © 2019 Jeddi et al

    Pneumothorax complicating isolated clavicle fracture

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    Isolated clavicle fractures are among the commonest of traumatic fractures in the emergency department. Complications of isolated clavicle fractures are rare. Pneumothorax has been described as a complication of a fractured clavicle only rarely in English literature. In all the reported cases, the pneumothorax was treated by a thoracostomy and the clavicle fracture was treated conservatively. In our case, the pneumothorax required a chest drain insertion and the clavicle fracture was treated surgically with good result

    Corrigendum to �Usability evaluation of a comprehensive national health information system: A heuristic evaluation� Inf Med Unlocked 19 (2020) 100332(S2352914820301064)(10.1016/j.imu.2020.100332)

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    The authors regret for the inconvenience. After reviewing the article, we determined that the grant number is not mentioned in the fund section. Please add the grant number 96049 to this section. Funding This study was funded by The Research Deputy of Kashan University of Medical Sciences under Grant (Number: 96049). The authors would like to apologise for any inconvenience caused. © 2020 The Author(s

    Usability evaluation of a comprehensive national health information system: A heuristic evaluation

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    Aim: to evaluate the usability of a comprehensive national health information system by the heuristic method. Introduction: Presently, information systems are widely being used in healthcare settings. Methods: Five independent evaluators assessed the user interface design of this system in terms of its compliance with a set of predetermined standard principles, also known as Jakob Nielsen's 10 general principles. Problems were reassessed in the presence of all evaluators, and similar cases were merged and a single list of unique problems was prepared. After a second assessment, the evaluators determined and categorized problem severity in five domains, including: the absence of a problem (zero point), a cosmetic problem (1 point), a minor problem (2 points), a major problem (3 points) and a catastrophic problem (4 points). Data were then analyzed in a spreadsheet using descriptive statistical tests. Results: The “recognition rather than recall” principle with 13 problems (21.3 of all cases) had the greatest frequency among all problems, while the “match between system and the real world” and “help and documentation” principles with 1 problem (1.6 of all cases) had the least frequency. Moreover, principles such as “help users recognize, diagnose and recover from errors”, “error prevention”, and “help and documentation” had a mean severity of 2.8, 2.8, and 3.4, respectively. Consequently, they were considered as catastrophic and major problems. Conclusions: Based on the viewpoint of evaluation experts, a large portion of problems in this system were classified into major and catastrophic categories, which primarily indicates the poor usability of this system. Therefore, it is highly recommended that authorities be notified of the issues in writing in order to resolve them in a future update. Finally, special consideration should be given to the meticulous evaluation of these systems during preliminary stages of design and development, so as to encounter fewer issues on a national level at the time of implementation. © 2020 The Author

    Heavy metals in recycled pastry packages and pastries

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    The safe use of recycled paper and board material for food packaging applications is a major area of investigations. Therefore, the aim of current study was to evaluate the amount of heavy metals in recycled paper pastry packages and measurement of migration over the time into pastries. In this study, the presence of heavy metals in common confectionery packaging and effects of storage time and kind of pastry on the migration are investigated. The results of the study indicate that harmful metals such as Pb are detected at high concentrations in most of the recycled boxes that are used for pastry packaging, and heavy metals could migrate from the recycled packages into food during usage. It seems that the procedure of preparing recycled paperboard for food packaging should be reconsidered

    Effects of Chlamydia trachomatis Infection on Fertility; A Case-Control Study.

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    BACKGROUND: Nowadays, Chlamydia trachomatis is known as a causative agent of infertility. Because of, asymptomatic nature of infection, many may suffer from its lasting complications such as infertility. This study was performed in Tehran during April 2007 to April 2008 to compare the prevalence of Chlamydia trachomatis infection in fertile and infertile women using ELISA and PCR methods. METHODS: Overall, 234 infertile and 223 pregnant women, as the fertile group, participated in this hospital-based case-control study. After completing an informed consent form and the questionnaire, first catch urine and blood sample were obtained for PCR and ELISA (IgG, IgM) tests, respectively. Logistic regression analysis was used to control possible confounding factors, and determine adjusted odds ratio of infertility due to the infection. RESULTS: PCR results revealed that 29 (12.4%) of the infertile and 19 (8.5%) of the fertile women were positive for C. trachomatis infection (p = 0.440). IgG was positive in 21 (9.0%) of the infertile and 11 (5.0%) in the fertile group (p = 0.093). IgM assays identified that 2 (0.9%) of the infertile and 4 (1.8%) of the fertile women were positive for the micro-organism (p = 0.375). CONCLUSION: We found no significant differences among fertile and infertile women for Chlamydia trachomatis infection. Nevertheless, molecular techniques which are more sensitive, more specific and non-invasive can be used to detect C. trachomatis infection

    Genetic diversity and population structure of Leishmania infantum from Southeastern France : evaluation using Multi-Locus Microsatellite Typing

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    In the south of France, Leishmania infantum is responsible for numerous cases of canine leishmaniasis (CanL), sporadic cases of human visceral leishmaniasis (VL) and rare cases of cutaneous and muco-cutaneous leishmaniasis (CL and MCL, respectively). Several endemic areas have been clearly identified in the south of France including the Pyrenees-Orientales, Cevennes (CE), Provence (P), Alpes-Maritimes (AM) and Corsica (CO). Within these endemic areas, the two cities of Nice (AM) and Marseille (P), which are located 150 km apart, and their surroundings, concentrate the greatest number of French autochthonous leishmaniasis cases. In this study, 270 L. infantum isolates from an extended time period (1978-2011) from four endemic areas, AM, P, CE and CO, were assessed using Multi-Locus Microsatellite Typing (MLMT). MLMT revealed a total of 121 different genotypes with 91 unique genotypes and 30 repeated genotypes. Substantial genetic diversity was found with a strong genetic differentiation between the Leishmania populations from AM and P. However, exchanges were observed between these two endemic areas in which it seems that strains spread from AM to P. The genetic differentiations in these areas suggest strong epidemiological structuring. A model-based analysis using STRUCTURE revealed two main populations: population A (consisting of samples primarily from the P and AM endemic areas with MON-1 and non-MON-1 strains) and population B consisting of only MON-1 strains essentially from the AM endemic area. For four patients, we observed several isolates from different biological samples which provided insight into disease relapse and re-infection. These findings shed light on the transmission dynamics of parasites in humans. However, further data are required to confirm this hypothesis based on a limited sample set. This study represents the most extensive population analysis of L. infantum strains using MLMT conducted in France

    Comparative expression profile of orphan receptor tyrosine kinase ROR1 in Iranian patients with lymphoid and myeloid leukemias

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    It has recently been shown that ROR1, a member of the receptor tyrosine kinase family, is overexpressed in leukemic B cells of Chronic Lymphocytic Leukemia (CLL) and a subset of Acute Lymphoblastic Leukemia (ALL). In this comparative study the expression profile of ROR1 mRNA was investigated in Iranian patients with CLL and Acute Myelogenous Leukemia (AML) and the results were compared with those previously reported in our Iranian ALL patients. RT-PCR was performed on bone marrow and/or peripheral blood samples of 84 CLL and 12 AML patients. CLL samples were classified into immunoglobulin heavy chain variable region (IGHV) gene mutated (n = 55) and unmutated (n = 29) and also indolent (n = 42) and progressive (n = 39) subtypes. ROR1 expression was identified in 94% of our CLL patients, but none of the AML patients expressed ROR1. No significant differences were observed between different CLL subtypes for ROR1 expression. Taken together the present data and our previous results on ROR1 expression in ALL, our findings propose ROR1 as a tumor-associated antigen overexpressed in a large proportion of lymphoid (CLL and ALL), but not myeloid (AML) leukemias. Expression of ROR1 seems to be associated to lineage and differentiation stages of leukemic cells with a potential implication for immunotherapy.Tehran University of Medical SciencesPublishe

    Epidemic assessment of bacterial agents in osteomyelitis and their antibiotic resistance pattern determination

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    The aim of the present study was to determine the causative agents of osteomyelitis and specifying their antibiotic resistance pattern in patients referred to pediatrics ward of Imam Khomeini Hospital. This study has been performed in Tehran during January to December 2006. In this study, Synovial fluid was taken from 90 patients who referred to pediatrics ward of Imam Khomeini. Samples were examined by direct test, culture and biochemical tests. In next step, antibiogram by disk diffusion method (Kirby-Bauer Test) was established on each positive sample and finally, the results were analyzed. Of 90 examined samples, 27 bacterial cases were isolated; Staphylococcus aureus with 55.9 was the most epidemic agent and Klebsiella sp., coagulase negative Staphylococci, Streptococcus pneumoniae and Enterobacter sp. were the next common agents, respectively. However, it was revealed that more than 40 Staphylococcus aureus are sensitivity to Vacomycin, Gentamicin, Sulfamethoxazole and Erythromycin and most of gram negative Rods isolated of were sensitivity to Amikacin, Ampicillin and Cephalothin (50-100). The most of bacteria (Staphylococcus aureus, coagulase negative Staphylococci, Streptococcus pneumoniae and Enterobacter sp.) were sensitive to Vancomycin, gentamicin and Cephalothin. Similar to previous results, it was proved either in our study that Staphylococcus aureus is the main agent of osteomyelitis and gram negative bacteria with coagulase negative Staphylococci and Streptococci are other agents. Also, it was observed that the most isolated bacteria had high antibiotic resistance to common drugs. © 2008 Asian Network for Scientific Information
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