Un nuevo códice con obras de Quevedo en la Real Academia de Buenas Letras de Barcelona

En este artículo se describe y estudia un nuevo manuscrito con obras en prosa y verso de Francisco de Quevedo; datable a inicios del siglo XVIII, se conserva, en buen estado, en la Real Academia de Buenas Letras de Barcelona como parte del legado de Guillermo Díaz-Plaja. Por su contenido (prosa histórica, abundante producción satírica y burlesca, algún poema amoroso y moral; mezcla de obras auténticas y otras atribuidas) se acerca a otros manuscritos de la misma época utilizados para fijar los textos de las distintas obras. Un primer cotejo revela que no se trata de un codex descriptus y por ello puede aportar textos y variantes interesantes. Parecen destacables, por ejemplo, su texto de la Vida de corte, los fragmentos de Mundo caduco o las variantes de algunos poemas, comentadas y recogidas luego íntegramente en apéndice

Fractionation and fluxes of metals and radionuclides during the recycling process of phosphogypsum wastes applied to mineral CO2 sequestration

The industry of phosphoric acid produces a calcium-rich by-product known as phosphogypsum, which is usually stored in large stacks of millions of tons. Up to now, no commercial application has been widely implemented for its reuse because of the significant presence of potentially toxic contaminants. This work confirmed that up to 96% of the calcium of phosphogypsum could be recycled for CO2 mineral sequestration by a simple two-step process: alkaline dissolution and aqueous carbonation, under ambient pressure and temperature. This CO2 sequestration process based on recycling phosphogypsum wastes would help to mitigate greenhouse gasses emissions. Yet this work goes beyond the validation of the sequestration procedure; it tracks the contaminants, such as trace metals or radionuclides, during the recycling process in the phosphogypsum. Thus, most of the contaminants were transferred from raw phosphogypsum to portlandite, obtained by dissolution of the phosphogypsum in soda, and from portlandite to calcite during aqueous carbonation. These findings provide valuable information for managing phosphogypsum wastes and designing potential technological applications of the by-products of this environmentally-friendly proposal.Junta de Andalucía P10-RNM-6300, P12- RNM-226

Francisco de Quevedo, alias «Diablo Cojuelo». Pasajes, hechos e hipótesis de alusiones en la novela de Vélez de Guevara con la figura de Quevedo al fondo

The trace of Quevedo can be seen in the novel by Luis Vélez de Guevara, El Diablo Cojuelo, in multiple aspects: from the techniques of «apodo» and caricature used by Quevedo in his literary self-portraits to the image and the literary figure of himself he built, from the nickname with which he was known as «Diablo Cojuelo» to the legends he starred in. Everything seems to show that when writing his novel, Luis Vélez had it more present than what has been recognized so far.La huella de Quevedo se puede percibir en la novela de Luis Vélez de Guevara, El diablo Cojuelo, en múltiples aspectos: desde las técnicas del apodo y la caricatura utilizadas por Quevedo en sus autorretratos literarios hasta la imagen y la figura literaria que de sí mismo construyó, desde el apodo con el que se le conocía de «Diablo Cojuelo» hasta las leyendas que protagonizó. Todo parece demostrar que al escribir su novela, Luis Vélez lo tuvo más presente de lo que hasta ahora se ha reconocido

Francisco de Quevedo por las sendas de la sátira menipea

En este artículo se ofrece un estudio panorámico de las sátiras menipeas de Francisco de Quevedo con especial atención a los recursos utilizados, los diversos modelos literarios para las distintas obras, su evolución así como otros factores que influyeron decisivamente en su composición, como fue la propia censura.The author of this article offers a panoramic study of Quevedo’s Menippean satire, with a special attention to the used sources, the different literary models to his works, their evolution and other aspects that affected critically to their composition, as it was his own censorship

Sensing of transposable elements by the antiviral innate immune system

We thank Dr. Francisco Sanchez-Luque, Dr. Martin Reijns, and Priscilla Chin for helpful discussions and comments on the manuscript. This work was funded by grants from the Wellcome Trust 107665/Z/15/Z and Royal Society grant RGS\R1\191368 to S.M., and from MINECO SAF2015-71589-P and Ramon y Cajal grant RYC-2016-21395 to S.R.H. Figures were designed using Smart Servier Medical Art (https://smart.servier.com).Around half of the genomes in mammals are composed of transposable elements (TEs) such as DNA transposons and retrotransposons. Several mechanisms have evolved to prevent their activity and the detrimental impact of their insertional mutagenesis. Despite these potentially negative effects, TEs are essential drivers of evolution, and in certain settings, beneficial to their hosts. For instance, TEs have rewired the antiviral gene regulatory network and are required for early embryonic development. However, due to structural similarities between TE-derived and viral nucleic acids, cells can misidentify TEs as invading viruses and trigger the major antiviral innate immune pathway, the type I interferon (IFN) response. This review will focus on the different settings in which the role of TE-mediated IFN activation has been documented, including cancer and senescence. Importantly, TEs may also play a causative role in the development of complex autoimmune diseases characterized by constitutive type I IFN activation. All these observations suggest the presence of strong but opposing forces driving the coevolution of TEs and antiviral defense. A better biological understanding of the TE replicative cycle as well as of the antiviral nucleic acid sensing mechanisms will provide insights into how these two biological processes interact and will help to design better strategies to treat human diseases characterized by aberrant TE expression and/ or type I IFN activation.Wellcome TrustEuropean Commission 107665/Z/15/ZRoyal Society of London RGS\R1\191368MINECO SAF2015-71589-PSpanish Government RYC-2016-2139

Publicidad conjunta marca-causa: el papel de la implicación del individuo hacia la publicidad en la comprensión y evaluación del mensaje. = Brand/cause advertising: The role of the individual's involvement toward the understanding and evaluation of the ad message

El efecto que tienen los anuncios que incorporan mensajes de marketing con causa (MCC) sobre el comportamiento del consumidor es uno de los aspectos que mayor interés ha despertado en la literatura reciente. La implicación hacia la marca o la causa es uno de los antecedentes frecuentemente incluidos en los modelos de respuesta a estos mensajes de MCC. Sin embargo, este tipo de implicación supone la existencia de una afinidad previa, bien con un elemento bien con el otro, aspecto que podría introducir cierto sesgo a la hora de analizar la influencia real que tienen este tipo de acciones de comunicación. En este trabajo analizamos de qué manera la implicación del individuo con el mensaje influye en la valoración de los mensajes conjuntos y en la actitud del sujeto hacia la marca. Esta implicación es totalmente extrínseca y se construye en el momento de percibir el anuncio, de modo que solo exige al individuo que se fije en el anuncio, pero no requiere una vinculación previa ni con la marca ni con la causa. Para ello, se desarrolla un estudio empírico en 2 etapas que confirma que dicha implicación facilita que el individuo preste atención al mensaje, contribuye a que la información sea valorada correctamente y favorece la evaluación de la campaña. = The influence of cause-related marketing campaigns on consumer behaviour is a key topic of interest in recent marketing literature. Both brand- and cause-related individual's involvement are frequently incorporated into consumer response models. However, such involvements are based on the premise of a strong level of affinity towards the brand or the cause. As a consequence, a biased estimation of the ‘real’ influence of these campaigns on consumer behaviour should be estimated. The aim of this paper is to analyse how an individual's involvement toward the ads influences his/her assessment of joint (brand-cause) messages and his/her attitude towards the brand. This involvement is extrinsic, and does not involve any previous relationship with either the brand or the cause. With this aim, a two-step empirical study is developed. The results confirm that such involvement makes it easier for the individual to pay attention to the message. It also contributes to the information being correctly evaluated and favours the evaluation of marketing campaigns

Charge Transfer in Partition Theory

The recently proposed Partition Theory (PT) [J.Phys.Chem.A 111, 2229 (2007)] is illustrated on a simple one-dimensional model of a heteronuclear diatomic molecule. It is shown that a sharp definition for the charge of molecular fragments emerges from PT, and that the ensuing population analysis can be used to study how charge redistributes during dissociation and the implications of that redistribution for the dipole moment. Interpreting small differences between the isolated parts' ionization potentials as due to environmental inhomogeneities, we gain insight into how electron localization takes place in H2+ as the molecule dissociates. Furthermore, by studying the preservation of the shapes of the parts as different parameters of the model are varied, we address the issue of transferability of the parts. We find good transferability within the chemically meaningful parameter regime, raising hopes that PT will prove useful in chemical applications.Comment: 12 pages, 16 figure

Natural Analogue Constraints on Europa's Non-ice surface Material

Non-icy material on the surface of Jupiter’s moon Europa is hypothesised to have originated from its subsurface ocean, and thus provide a record of ocean composition and habitability. The nature of this material is debated, but observations suggest that it comprises hydrated sulfate and chloride salts. Analogue spectroscopic studies have previously focused on single phase salts under controlled laboratory conditions. We investigated natural salts from perennially cold (<0 °C) hypersaline springs, and characterised their reflectance properties at 100 K, 253 K and 293 K. Despite similar major ion chemistry, these springs form mineralogically diverse deposits, which when measured at 100 K closely match reflectance spectra from Europa. In the most sulfate-rich samples, we find spectral features predicted from laboratory salts are obscured. Our data are consistent with sulfate-dominated europan non-icy material, and further, show that the emplacement of endogenic sulfates on Europa’s surface would not preclude a chloride-dominated ocean

Competition between polar and nonpolar lattice distortions in oxide quantum wells: new critical thickness at polar interfaces

Two basic lattice distortions permeate the structural phase diagram of oxide perovskites: antiferrodistortive (AFD) rotations and tilts of the oxygen octahedral network and polar ferroelectric modes. With some notable exceptions, these two order parameters rarely coexist in a bulk crystal, and understanding their competition is a lively area of active research. Here we demonstrate, by using the LaAlO₃/SrTiO₃ system as a test case, that quantum confinement can be a viable tool to shift the balance between AFD and polar modes and selectively stabilize one of the two phases. By combining scanning transmission electron microscopy (STEM) and first-principles-based models, we find a crossover between a bulklike LaAlO₃ structure where AFD rotations prevail, to a strongly polar state with no AFD tilts at a thickness of approximately three unit cells; therefore, in addition to the celebrated electronic reconstruction, our work unveils a second critical thickness, related not to the electronic properties but to the structural ones. We discuss the implications of these findings, both for the specifics of the LaAlO₃/SrTiO₃ system and for the general quest towards nanoscale control of material properties

Designing a hotel website: An empirical analysis for a classic destination using a conjoint experiment

Internet has become one of the most important channels for the promotion and sale of services related to tourism. As a result, producers and distributors alike are keen to resolve the question as to which factors will determine website choice by internet browsers. In this paper we develop an experiment to determine the factors that need to be taken into consideration when designing a website for a mature, familiar tourist destination. To this end, the basic factors shaping the architecture of a website are theoretically described and, based on the results of a conjoint experiment, the main factors influencing a website for a classic destination are extracted. Our results suggest that a website that includes objective information (e.g., price, activities of interest, number of rooms) and multiple photos has a positive influence on customer perceptions. The paper also makes an important methodological contribution, as it proposes a new design for calculating the weight of the factors, interactions of two factors and the factors squared