97 research outputs found
Non local damage model Boundary and evolving boundary effects
International audienceThe present contribution aims at providing a closer insight on boundary effects in non local damage modelling. From micromechanics, we show that on a boundary interaction stress components normal to the surface should vanish. These interaction stresses are at the origin of non locality and therefore the material response of points located on the boundary should be partially local. Then, we discuss a tentative modification of the classical non local damage model aimed at accounting for this effect due to existing boundaries and also boundaries that arise from crack propagation. One-dimensional computations show that the profiles of damage are quite different compared to those obtained with the original formulation. The region in which damage is equal to 1 is small. The modified model performs better at complete failure, with a consistent description of discontinuity of the displacement field after failure
Width distribution of contact lines on a disordered substrate
We have studied the roughness of a contact line of a liquid meniscus on a
disordered substrate by measuring its width distribution. The comparison
between the measured width distribution and the width distribution calculated
in previous works, extended here to the case of open boundary conditions,
confirms that the Joanny-de Gennes model is not sufficient to describe the
dynamics of contact lines at the depinning threshold. This conclusion is in
agreement with recent measurements which determine the roughness exponent by
extrapolation to large system sizes.Comment: 4 pages, 3 figure
On the complexity of acyclic modules in automata networks
Modules were introduced as an extension of Boolean automata networks. They
have inputs which are used in the computation said modules perform, and can be
used to wire modules with each other. In the present paper we extend this new
formalism and study the specific case of acyclic modules. These modules prove
to be well described in their limit behavior by functions called output
functions. We provide other results that offer an upper bound on the number of
attractors in an acyclic module when wired recursively into an automata
network, alongside a diversity of complexity results around the difficulty of
deciding the existence of cycles depending on the number of inputs and the size
of said cycle.Comment: 21 page
2-loop Functional Renormalization Group Theory of the Depinning Transition
We construct the field theory which describes the universal properties of the
quasi-static isotropic depinning transition for interfaces and elastic periodic
systems at zero temperature, taking properly into account the non-analytic form
of the dynamical action. This cures the inability of the 1-loop flow-equations
to distinguish between statics and quasi-static depinning, and thus to account
for the irreversibility of the latter. We prove two-loop renormalizability,
obtain the 2-loop beta-function and show the generation of "irreversible"
anomalous terms, originating from the non-analytic nature of the theory, which
cause the statics and driven dynamics to differ at 2-loop order. We obtain the
roughness exponent zeta and dynamical exponent z to order epsilon^2. This
allows to test several previous conjectures made on the basis of the 1-loop
result. First it demonstrates that random-field disorder does indeed attract
all disorder of shorter range. It also shows that the conjecture zeta=epsilon/3
is incorrect, and allows to compute the violations, as zeta=epsilon/3 (1 +
0.14331 epsilon), epsilon=4-d. This solves a longstanding discrepancy with
simulations. For long-range elasticity it yields zeta=epsilon/3 (1 + 0.39735
epsilon), epsilon=2-d (vs. the standard prediction zeta=1/3 for d=1), in
reasonable agreement with the most recent simulations. The high value of zeta
approximately 0.5 found in experiments both on the contact line depinning of
liquid Helium and on slow crack fronts is discussed.Comment: 32 pages, 17 figures, revtex
Bursts in a fiber bundle model with continuous damage
We study the constitutive behaviour, the damage process, and the properties
of bursts in the continuous damage fiber bundle model introduced recently.
Depending on its two parameters, the model provides various types of
constitutive behaviours including also macroscopic plasticity. Analytic results
are obtained to characterize the damage process along the plastic plateau under
strain controlled loading, furthermore, for stress controlled experiments we
develop a simulation technique and explore numerically the distribution of
bursts of fiber breaks assuming infinite range of interaction. Simulations
revealed that under certain conditions power law distribution of bursts arises
with an exponent significantly different from the mean field exponent 5/2. A
phase diagram of the model characterizing the possible burst distributions is
constructed.Comment: 9 pages, 11 figures, APS style, submitted for publicatio
Matrix-Bound PAI-1 Supports Cell Blebbing via RhoA/ROCK1 Signaling
The microenvironment of a tumor can influence both the morphology and the behavior of cancer cells which, in turn, can rapidly adapt to environmental changes. Increasing evidence points to the involvement of amoeboid cell migration and thus of cell blebbing in the metastatic process; however, the cues that promote amoeboid cell behavior in physiological and pathological conditions have not yet been clearly identified. Plasminogen Activator Inhibitor type-1 (PAI-1) is found in high amount in the microenvironment of aggressive tumors and is considered as an independent marker of bad prognosis. Here we show by immunoblotting, activity assay and immunofluorescence that, in SW620 human colorectal cancer cells, matrix-associated PAI-1 plays a role in the cell behavior needed for amoeboid migration by maintaining cell blebbing, localizing PDK1 and ROCK1 at the cell membrane and maintaining the RhoA/ROCK1/MLC-P pathway activation. The results obtained by modeling PAI-1 deposition around tumors indicate that matrix-bound PAI-1 is heterogeneously distributed at the tumor periphery and that, at certain spots, the elevated concentrations of matrix-bound PAI-1 needed for cancer cells to undergo the mesenchymal-amoeboid transition can be observed. Matrix-bound PAI-1, as a matricellular protein, could thus represent one of the physiopathological requirements to support metastatic formation
Root-emitted volatile organic compounds: can they mediate belowground plant-plant interactions?
peer reviewedBackground
Aboveground, plants release volatile organic compounds (VOCs) that act as chemical
signals between neighbouring plants. It is now well documented that VOCs emitted by
the roots in the plant rhizosphere also play important ecological roles in the soil
ecosystem, notably in plant defence because they are involved in interactions between
plants, phytophagous pests and organisms of the third trophic level. The roles played
by root-emitted VOCs in between- and within-plant signalling, however, are still poorly
documented in the scientific literature.
Scope
Given that (1) plants release volatile cues mediating plant-plant interactions
aboveground, (2) roots can detect the chemical signals originating from their
neighbours, and (3) roots release VOCs involved in biotic interactions belowground,
the aim of this paper is to discuss the roles of VOCs in between- and within-plant
signalling belowground. We also highlight the technical challenges associated with the
analysis of root-emitted VOCs and the design of experiments targeting volatile-mediated
root-root interactions.
Conclusions
We conclude that root-root interactions mediated by volatile cues deserve more
research attention and that both the analytical tools and methods developed to study
the ecological roles played by VOCs in interplant signalling aboveground can be
adapted to focus on the roles played by root-emitted VOCs in between- and within-plant
signalling
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