Pelatihan Penggunaan Sistem Informasi Pengelolaan Surat Keluar di Desa Dunggala Kecamatan Tapa Kabupaten Bone Bolango

Assessment of good government performance is characterized by the quality of its services to the community. One of the roles of the village as the lowest administrative level in a region is to serve the community in making letters. Management of outgoing mail in Desa Dunggala, Kecamatan Tapa, Kabupaten Bone Bolango is still done conventionally, namely by recording the letter number in the agenda book. This resulted in village officials experiencing difficulties in managing the correspondence archives if in the future a letter with a certain number was needed. This community service activities aimed at helping the village government in managing outgoing mail by designing information system for managing outgoing mail. The information system was built based on the web application, but in its application is still used offline or localhost, due to internet network constraints in the village office. A database system is used for data storage so that it is easy to search the letters that have been made. Then, the village officials has been trained to use the information system. The results obtained from this activity are the information system for managing outgoing mail and the training of village officials in using the application. This information system can be further developed by taking into account the needs that exist in the village

The Application Design of Interactive Multimedia of IT-based Mathematics Learning on Strengtening Students' Characters

This research aims to develop interactive multimedia application of Coordinate System-based on the strengthening of Grade VIII Junior High students’ characters. The development model used in this study refers to the 4-D model proposed by Thiagarajan, Semmel and Semmel consisting of Define, Design, Develop, and Disseminate stages. Product development was tested on 20 students and field test was conducted in three junior high schools namely SMPN 3 Gorontalo, SMPN 1 Kabila Bone Bolango District and SMPN 11 Gorontalo City. The results of this study indicate that interactive multimedia Coordinate System that has been developed: (1) Categorized valid and feasible according to the expert; (2) Multimedia interactive coordinate system is easy to use and improves learners' response in learning. In addition, the implementation of learning by using multimedia coordinate system is in very good criteria, (3) Multimedia can improve the activity and learning outcomes of learners which based on observations obtained the percentage of student activities by 89.75% for limited and average trial class percentage for the field trial class of 94.87% with very good criteria.Students' learning outcomes provide classical completeness data for the limited trial class of 87.50% and field trial classes obtained by an average percentage of 89.33% with very good criteria, (4) Improving character based on the above, the interactive Multimedia coordinate system developed has been said to be valid, practical and effective so that it can be used in the process of Mathematics learning at grade VIII Junior High School

The Development of Character Building-Based Two-Dimensional Shapes Multimedia on Junior High School Students in Gorontalo Province, Indonesia

Mathematics is a branch of natural sciences that is capable of developing character and ability to think systematically, logically, and critically in expressing ideas or solving problems. To develop student

Designing User-Friendly Grids for the Gender-Specification of Rural, Semi-Urban, and Urban School Toilets in West Africa: Lessons from the Republic of Benin

Gender equity, quality education, and sanitation in rural and urban areas are widely considered as development imperatives. However, while many countries of the world are already far with the gendering of their schools’ toilets, most others still tend to systematically construct the same number of toilet cabins for female and male students, often ignoring specific needs associated with biophysical differences and disabilities among the students. This poor gendering of school toilets prevailed in the Republic of Benin until 2013, when, within the framework of the Pluriannual Water and Sanitation Programme (PPEA phase 2) funded by the Netherlands’ Ministry of Cooperation through its Embassy in the Republic of Benin, the Directorate of Hygiene and Sanitation of the Ministry of Public Health in collaboration with Water and Sanitation for Africa Agency, decided to launch a study for gender and disability specific toilets in primary and secondary schools. This original paper discusses the process towards the design of norms and grids for the calculation of toilet cabins and urinals needs of primary and secondary school students of rural, semi-urban, urban, Sahelian, Sudanian, lake, and coastal areas of the Republic of Benin. The study took place in four steps. The first step consisted of identifying key factors that affect the use of school toilets by students, especially female and disabled students. The second step consisted of observing and recording the use of school toilets by students, and building on those observations and records to estimate the number of toilet cabins and urinals required per agroecological and sociocultural area. The third step built on the results from the first and second steps to design simplified grids that allow sanitation and schools’ decision-makers to easily and quickly calculate the number of toilet cabins and urinals required for the target schools, per gender and disability. The fourth step consisted of building the capacities of potential users of the grids, for their relevant use. The findings indicate a variation of needs among primary and secondary schools, and the study zones, due to sociocultural and development differences. The grids have been in use in Benin since 2016 and it has easily helped to calculate gender-specific toilet needs in the study areas. After five years of use, their performance requires to be assessed for further adaptations. A further paper will report on the performance of these grids

Plant genetic resources and food security in West and Central Africa: Regional Conference, 26-30 April 2004

The Regional Conference on Plant Genetic Resources and Food Security in West and Central Africa was held at the International Institute of Tropical Agriculture (IITA), Ibadan, Nigeria from 26 to 30 April 2004. Ninety-five scientists and agricultural research managers from 13 countries and 18 institutions and organizations attended the conference that was organized under the auspices of Conseil Ouest et Centre Africain pour la Recherche et le Développement (CORAF). It took about two years to organize it. Partner institutions including the Conference of Directors for Agronomic Research in West and Central Africa (CORAF), Bioversity International, the International Institute of Topical Agriculture (IITA), Food and Agriculture Organization (FAO), the West Africa Rice Development Association (WARDA), the International Crops Research Institute for Semi-Arid Tropics (ICRISAT), the Desert Margin Programme (DMP), the World Agroforestry Centre (ICRAF), the System-Wide Genetic Resources Programme (SGRP) and the Genetic Resources Policy Initiative (GRPI) co-funded and organized the conference assisted by the Technical Centre for Agricultural and Rural Cooperation (CTA) and Syngenta. The main outcomes from the deliberations are presented in this synthesis report. The main goal of the conference was to provide a forum for assessing the state of plant genetic resources (PGR) conservation and management in West and Central Africa (WCA), and to explore methods of strengthening regional collaboration. The specific objectives were: To assess the state of, and mechanisms for, management and sustainable use of plantgenetic resources in WCA countries;To enhance awareness on new global and regional plant genetic resources (PGR)developments and policy frameworks;To establish mechanisms and strategies for promotion of collaboration and coordination at regional and country levels on PGR conservation, management and policies in the sub-region. This conference gave a unique opportunity to scientists in WCA to assess the state of genetic resources conservation, management and use in the sub-region. They explored mechanisms for strengthening regional collaboration and discussed how these resources can be managed to solve food insecurity in the region. The national research institutes, under the framework of CORAF and the various CGIAR Centres (Bioversity, IITA, WARDA, ICRISAT) working in WCA, and FAO decided to work closely together for the benefit of genetic resources. Many initiatives are already being developed in the region and the conference emphasised the necessity to link all those initiatives and to ensure that the region is not left out in genetic resources conservation and use. The conference ended with a declaration and communiqué

Designing User-Friendly Grids for the Gender-Specification of Rural, Semi-Urban, and Urban School Toilets in West Africa: Lessons from the Republic of Benin

Gender equity, quality education, and sanitation in rural and urban areas are widely considered as development imperatives. However, while many countries of the world are already far with the gendering of their schools’ toilets, most others still tend to systematically construct the same number of toilet cabins for female and male students, often ignoring specific needs associated with biophysical differences and disabilities among the students. This poor gendering of school toilets prevailed in the Republic of Benin until 2013, when, within the framework of the Pluriannual Water and Sanitation Programme (PPEA phase 2) funded by the Netherlands’ Ministry of Cooperation through its Embassy in the Republic of Benin, the Directorate of Hygiene and Sanitation of the Ministry of Public Health in collaboration with Water and Sanitation for Africa Agency, decided to launch a study for gender and disability specific toilets in primary and secondary schools. This original paper discusses the process towards the design of norms and grids for the calculation of toilet cabins and urinals needs of primary and secondary school students of rural, semi-urban, urban, Sahelian, Sudanian, lake, and coastal areas of the Republic of Benin. The study took place in four steps. The first step consisted of identifying key factors that affect the use of school toilets by students, especially female and disabled students. The second step consisted of observing and recording the use of school toilets by students, and building on those observations and records to estimate the number of toilet cabins and urinals required per agroecological and sociocultural area. The third step built on the results from the first and second steps to design simplified grids that allow sanitation and schools’ decision-makers to easily and quickly calculate the number of toilet cabins and urinals required for the target schools, per gender and disability. The fourth step consisted of building the capacities of potential users of the grids, for their relevant use. The findings indicate a variation of needs among primary and secondary schools, and the study zones, due to sociocultural and development differences. The grids have been in use in Benin since 2016 and it has easily helped to calculate gender-specific toilet needs in the study areas. After five years of use, their performance requires to be assessed for further adaptations. A further paper will report on the performance of these grids

Differential household vulnerability to climatic and non-climatic stressors in semi-arid areas of Mali, West Africa

Semi-Arid Regions (SARs) of West Africa are considered climate change “hotspots” where strong ecological, economic and social impacts converge to make socio-ecological systems particularly vulnerable. While both climatic and non-climatic drivers interact across scales to influence vulnerability, traditionally, this inter-connectedness has received little attention in vulnerability assessments in the region. This study adopted the vulnerability patterns framework, operationalized using the Multidimensional Livelihood Vulnerability approach to include both climatic and nonclimatic stressors to analyze differential household vulnerability in SARs of Mali. Findings showed that while drought was the most mentioned climate-related stressor, households were also exposed to a diversity of environmental and socio-economic stressors, including food scarcity, livestock disease, labour unavailability, crop damage, and erratic rainfall patterns. The typology revealed three vulnerability archetypes differentiated by adaptive capacity and sensitivity. Availability of productive household members, household resource endowments, livelihood diversification and social networks were the main discriminant factors of household adaptive capacity, while challenges relating to food and water security make households more sensitive to stressors. The analysis highlighted the heterogeneity in household vulnerability patterns within and across communities. Failing to account for this heterogeneity in adaptation planning might result in a mismatch between adaptation needs and interventions, and potentially in maladaptation

Partial sequencing of the bottle gourd genome reveals markers useful for phylogenetic analysis and breeding

<p>Abstract</p> <p>Background</p> <p>Bottle gourd [<it>Lagenaria siceraria </it>(Mol.) Standl.] is an important cucurbit crop worldwide. Archaeological research indicates that bottle gourd was domesticated more than 10,000 years ago, making it one of the earliest plants cultivated by man. In spite of its widespread importance and long history of cultivation almost nothing has been known about the genome of this species thus far.</p> <p>Results</p> <p>We report here the partial sequencing of bottle gourd genome using the 454 GS-FLX Titanium sequencing platform. A total of 150,253 sequence reads, which were assembled into 3,994 contigs and 82,522 singletons were generated. The total length of the non-redundant singletons/assemblies is 32 Mb, theoretically covering ~ 10% of the bottle gourd genome. Functional annotation of the sequences revealed a broad range of functional types, covering all the three top-level ontologies. Comparison of the gene sequences between bottle gourd and the model cucurbit cucumber (<it>Cucumis sativus</it>) revealed a 90% sequence similarity on average. Using the sequence information, 4395 microsatellite-containing sequences were identified and 400 SSR markers were developed, of which 94% amplified bands of anticipated sizes. Transferability of these markers to four other cucurbit species showed obvious decline with increasing phylogenetic distance. From analyzing polymorphisms of a subset of 14 SSR markers assayed on 44 representative China bottle gourd varieties/landraces, a principal coordinates (PCo) analysis output and a UPGMA-based dendrogram were constructed. Bottle gourd accessions tended to group by fruit shape rather than geographic origin, although in certain subclades the lines from the same or close origin did tend to cluster.</p> <p>Conclusions</p> <p>This work provides an initial basis for genome characterization, gene isolation and comparative genomics analysis in bottle gourd. The SSR markers developed would facilitate marker assisted breeding schemes for efficient introduction of desired traits.</p

Re-evaluation of histological diagnoses of malignant mesothelioma by immunohistochemistry

<p>Abstract</p> <p>Background</p> <p>In order to provide reliable tissue material for malignant mesothelioma (MM) studies, we re-evaluated biopsies and autopsy material from 61 patients with a diagnosis of MM from the period of 1980-2002.</p> <p>Methods</p> <p>Basic positive (Calretinin, EMA, Podoplanin, Mesothelin) and negative (CEA, Ber-Ep4) immunohistochemical (IHC) marker reactions were determined. If needed, more markers were used. Histological diagnoses were made by three pathologists. Survival data were calculated.</p> <p>Results</p> <p>49 cases (80%) were considered being MM by a high degree of likelihood, five more cases possible MM. Of the remaining seven cases, three were diagnosed as adenocarcinoma, three as pleomorphic lung carcinoma, in one peritoneal case a clear entity diagnosis could not be given. One of the possible MM cases and two of the lung carcinoma cases had this already as primary diagnoses, but were registered as MM.</p> <p>With a sensitivity of 100%, Calretinin and CEA were the most reliable single markers. The amount of MM cells with positive immunoreactivity (IR) for Podoplanin and Mesothelin showed most reliable inverse relation to the degree of atypia.</p> <p>In the confirmed MM cases, there had been applied either no IHC or between one and 18 markers.</p> <p>The cases not confirmed by us had either lacked IHC (n = 1), non-specific markers were used (n = 4), IR was different (n = 1), or specific markers had not shown positive IR in the right part of the tumour cells (n = 3).</p> <p>46 of the 49 confirmed and three of the not confirmed cases had been diagnosed by us as most likely MM before IHC was carried out.</p> <p>Conclusions</p> <p>In order to use archival tissue material with an earlier MM diagnosis for studies, histopathological re-evaluation is important. In possible sarcomatous MM cases without any positive IR for positive MM markers, radiology and clinical picture are essential parts of diagnostics. IHC based on a panel of two positive and two negative MM markers has to be adapted to the differential diagnostic needs in each single case. New diagnostic tools and techniques are desirable for cases where IHC and other established methods cannot provide a clear entity diagnosis, and in order to improve MM treatment.</p