649 research outputs found

    Neoliberalism in the North American University: Toward Integrating Divisions in Agent Orientation Via a Follettian Differentiated Relational Ontology

    Get PDF
    This paper uses observations from empirical articles and personal experiences of the authors to explore issues associated with the rise of neoliberalism and academic capitalism in the contemporary public university. It frames these issues as stemming from conflicting ontologies between academicians who adhere to the differentiated individual ontology and university administrators who favor the undifferentiated individual ontology. To overcome the disconnect, a differentiated relational ontology that adheres to principles of Mary Parker Follett and Alfred North Whitehead is proposed. The driving force behind this ontology can be highlighted through a communicated crisis, and a specific application of Follett’s differentiated relational ontology is Ensemble Learning Theory (ELT). A potential limitation of this study is generalizability, because the focus is centered on North American public universities and anecdotes are used to characterize a broader educational problem. This evolution is pertinent to academicians and administrators because the ontological impasse experienced in North American public universities threatens their existence as institutions, and has a broader and potentially negative impact on the quality of educational focus and output

    Bony metastases from breast cancer - a study of foetal antigen 2 as a blood tumour marker

    Get PDF
    Background : Foetal antigen 2 (FA-2), first isolated in the amniotic fluid, was shown to be the circulating form of the aminopropeptide of the alpha 1 chain of procollagen type I. Serum concentrations of FA-2 appeared to be elevated in a number of disorders of bone metabolism. This paper is the first report of its role as a marker of bone metabolism in metastatic breast cancer. Methods: Serum FA-2 concentrations were measured by radioimmunoassay in 153 women with different stages of breast cancer and in 34 normal controls. Results: Serum FA-2 was significantly elevated in women with bony metastases (p < 0.015). Its levels were not significantly different among women with non-bony metastases, with non-metastatic disease, as well as among normal controls. Conclusions: FA-2 is a promising blood marker of bone metabolism. Further studies to delineate its role in the diagnosis and management of bony metastases from breast cancer are required

    Molecular and phylogenetic characterization of the sieve element occlusion gene family in Fabaceae and non-Fabaceae plants

    Get PDF
    <p>Abstract</p> <p>Background</p> <p>The phloem of dicotyledonous plants contains specialized P-proteins (phloem proteins) that accumulate during sieve element differentiation and remain parietally associated with the cisternae of the endoplasmic reticulum in mature sieve elements. Wounding causes P-protein filaments to accumulate at the sieve plates and block the translocation of photosynthate. Specialized, spindle-shaped P-proteins known as forisomes that undergo reversible calcium-dependent conformational changes have evolved exclusively in the <it>Fabaceae</it>. Recently, the molecular characterization of three genes encoding forisome components in the model legume <it>Medicago truncatula </it>(<it>MtSEO1</it>, <it>MtSEO2 </it>and <it>MtSEO3</it>; SEO = sieve element occlusion) was reported, but little is known about the molecular characteristics of P-proteins in non-<it>Fabaceae</it>.</p> <p>Results</p> <p>We performed a comprehensive genome-wide comparative analysis by screening the <it>M. truncatula</it>, <it>Glycine max</it>, <it>Arabidopsis thaliana</it>, <it>Vitis vinifera </it>and <it>Solanum phureja </it>genomes, and a <it>Malus domestica </it>EST library for homologs of <it>MtSEO1</it>, <it>MtSEO2 </it>and <it>MtSEO3 </it>and identified numerous novel <it>SEO </it>genes in <it>Fabaceae </it>and even non-<it>Fabaceae </it>plants, which do not possess forisomes. Even in <it>Fabaceae </it>some <it>SEO </it>genes appear to not encode forisome components. All <it>SEO </it>genes have a similar exon-intron structure and are expressed predominantly in the phloem. Phylogenetic analysis revealed the presence of several subgroups with <it>Fabaceae</it>-specific subgroups containing all of the known as well as newly identified forisome component proteins. We constructed Hidden Markov Models that identified three conserved protein domains, which characterize SEO proteins when present in combination. In addition, one common and three subgroup specific protein motifs were found in the amino acid sequences of SEO proteins. <it>SEO </it>genes are organized in genomic clusters and the conserved synteny allowed us to identify several <it>M. truncatula </it>vs <it>G. max </it>orthologs as well as paralogs within the <it>G. max </it>genome.</p> <p>Conclusions</p> <p>The unexpected occurrence of forisome-like genes in non-<it>Fabaceae </it>plants may indicate that these proteins encode species-specific P-proteins, which is backed up by the phloem-specific expression profiles. The conservation of gene structure, the presence of specific motifs and domains and the genomic synteny argue for a common phylogenetic origin of forisomes and other P-proteins.</p

    Paradoxes of creativity : examining the creative process through an antenarrative lens

    Get PDF
    Accounts of the creative process tend to be retrospective and implicitly ground the creative act within the person, the mind, the moment, the idea; in doing so, they often miss the larger sociomaterial qualities that can provide us with important insights about the social relationality and playfulness of the creative process. In this article, we examine the creative process through an antenarrative lens that we consider very useful for theorizing the creative process from a cultural and sociomaterial perspective. More specifically, we argue that ‘having an idea’ is a contextualized and embodied process that can be regarded as an antenarrative of the overall creative process. We also discuss how the paradoxical relation between the formative and sudden manifestations of the creative act can be understood through the notion of play

    Re-storying and visualizing the changing entrepreneurial identities of Bill Gates and Richard Branson.

    Get PDF
    The storytelling in textual and visual re-constructions of Bill Gates and Richard Branson by their organizations produces entrepreneurial identities bound into particular social power-knowledge relations. Our purpose is to examine how these organizations, and their critics, mobilize storytelling in acts of re-storying (enlivening) or re-narrating (branding a monologic) practices using Internet technologies to invite viewers to frame the world of entrepreneurship. We use visual discourse and storytelling methods to analyze how Microsoft and Virgin Group use various kinds of entrepreneurial images and textual narratives to re-narrate and produce particular brands of capitalism. These organizations' scoptic regimes of representation are contested in counter-visualizing and counterstory practices of external stakeholders. We suggest that the image and textual practices of storytelling have changed as both entrepreneurs court philanthropic and social entrepreneur identity markers. Our contribution to entrepreneurial identity is to apply double and multiple narrations, the appropriation of another's narrative words (or images) into another's narrative, and relate such storytelling moves to visuality

    Transient movements of a deep-water flatfish in coastal waters: Implications of inshore-offshore connectivity for fisheries management

    Get PDF
    1. Globally, small-scale inshore fisheries are being recognized as highly beneficial for underdeveloped coastal communities since they directly contribute to local economies. Community coastal fisheries, however, may target species that are simultaneously harvested by large commercial vessels in adjacent offshore waters, creating uncertainty over stock units and connectivity that complicate management. 2. Greenland halibut Reinhardtius hippoglossoides, a commercially important flatfish species in the Arctic, were tagged in Scott Inlet, coastal Baffin Island, Canada, with acoustic transmitters and tracked for a 1-year period. Our aim was to measure fish movement and connectivity between inshore habitats, where Inuit fisheries are developing, and offshore waters, where an established commercial fishery operates. Four movement metrics were established, and cluster analysis and a mixed effects model were used to define movement types and identify environmental covariates of the presence/absence within the coastal environment respectively. 3. Two distinct movement patterns were characterized for Greenland halibut; the majority were transients that were no longer detected inshore by the end of November (n = 47, 72%), and a smaller group of intermittently resident fish that moved into the offshore at the same time as transient fish, but returned to the coastal environment in the winter (n = 8, 12%), with the remainder being undefined. The presence of Greenland halibut in the inshore was negatively correlated with ice cover, indicating that fish moved offshore as sea ice formed. 4. Synthesis and applications. Greenland halibut were previously thought to be highly resident within the coastal environment of Baffin Bay; however, our data demonstrates that this is not true for all areas. In Scott Inlet and adjacent coastal regions, Greenland halibut exhibit complex inshore-offshore connectivity, suggesting inshore and offshore fisheries require a shared quota. We recommend that in the face of developing global small-scale coastal fisheries, improved understanding of stock connectivity between environments is required to sustainably manage commercial fish species

    Reaching across continents : engaging students through virtual collaborations

    Get PDF
    Business schools have the responsibility of preparing students for work in multicultural organizations and global markets. This paper examines a situated learning experience for undergraduates through a virtual collaboration between a UK university and a Brazilian university. This facilitated remote communication using social media and smart devices, allowing students from both institutions to enhance their cross-cultural management competencies. A qualitative approach was used for the research, drawing on the reflections of the tutors from both institutions, and feedback received from students in the UK and Brazil. This paper provides empirical observations regarding the use of this innovative pedagogic approach, generating discussion of the implications for teaching, thus contributing to the literature on international collaborations in cross-cultural management education
    corecore