Разработка комплексной системы управления складом для интернет-магазинов

В результате исследовательской работы была спроектирована и разработана комплексная система управления складом для интернет-магазинов. Система позволяет интегрировано вести учет и визуализировать расположение продукции на складе, регистрировать расходы, управлять ресурсами и отображать финансовую статистику бюджета компании.As a result of the research work, a comprehensive warehouse management system for online shopping stores was designed and developed. The system allows integrated accounting and visualization of the location of products in the warehouse, recording expenses, managing resources and displaying financial statistics of the company's budget

Neuroprotective effects of curcumin and apocynin on spatial memory performance in an animal model of acute neuroinflammation / Efeitos neuroprotetores de curcumina e apocinina sobre o desempenho em memória espacial em modelo animal de neuroinflamação aguda

Neuroinflammation is closely related to the etiology of several neurological/neurodegenerative diseases. These disorders cause cognitive impairment and sensitization of the immune system to internal and/or external stimuli. This work aims to evaluate the neuroprotective effects of the phytochemical compounds curcumin and apocynin on the spatial memory of rats in a model of acute neuroinflammation. For this, the study was divided into two phases. First, the dose of lipopolysaccharide (LPS) able to cause neuroinflammation and consequently mnemonic damage to the animals was tested. In the second phase, the neuroprotective effect of curcumin and apocynin was assessed. At two days after the surgery, the treatment with curcumin 50 mg/kg dissolved in vegetable oil was administered by gavage to saline + curcumin and LPS + curcumin groups. On the same day, animals from groups saline + apocynin and LPS + apocynin received by gavage apocynin 50 mg/kg suspended in distilled water. Rats of saline + vehicle and LPS + vehicle groups received vegetable oil or distilled water. The gavage treatment was given for 30 days for all groups. The spatial memory evaluation was assessed by Morris Water Maze (MWM) task, performed 30 days after the surgery in the first phase of the study and 1 day after the last gavage treatment in the second phase, both for 5 consecutive days. The MWM test trial was conducted 24 hours after the last training session. We found that the intra-hippocampal infusion of LPS, performed 30 days before training in the MWW task, impaired the retention of spatial memory acquired in this task. It also caused histopathological alterations in the infusion region, which are compatible with both acute and chronic neuroinflammation. Oral administration of apocynin, but not curcumin, reversed the mnemonic deficit and mitigated the histopathological alterations caused by the intra-hippocampal infusion of LPS

VLTI-MATISSE L- and N-band aperture-synthesis imaging of the unclassified B[e] star FS Canis Majoris

Stars and planetary system

First MATISSE L-band observations of HD 179218: is the inner 10 au region rich in carbon dust particles?

Stars and planetary system

MATISSE, the VLTI mid-infrared imaging spectro-interferometer

GalaxiesStars and planetary systemsInstrumentatio

VLTI-MATISSE L- and N-band aperture-synthesis imaging of the unclassified B[e] star FS Canis Majoris★

This is the final version. Available from EDP Sciences via the DOI in this record. Context. FS Canis Majoris (FS CMa, HD 45677) is an unclassified B[e] star surrounded by an inclined dust disk. The evolutionary stage of FS CMa is still debated. Perpendicular to the circumstellar disk, a bipolar outflow was detected. Infrared aperture-synthesis imaging provides us with a unique opportunity to study the disk structure. Aims. Our aim is to study the intensity distribution of the disk of FS CMa in the mid-infrared L and N bands. Methods. We performed aperture-synthesis imaging of FS CMa with the MATISSE instrument (Multi AperTure mid-Infrared SpectroScopic Experiment) in the low spectral resolution mode to obtain images in the L and N bands. We computed radiative transfer models that reproduce the L- and N-band intensity distributions of the resolved disks. Results. We present L- and N-band aperture-synthesis images of FS CMa reconstructed in the wavelength bands of 3.4-3.8 and 8.6-9.0 μm. In the L-band image, the inner rim region of an inclined circumstellar disk and the central object can be seen with a spatial resolution of 2.7 milliarcsec (mas). An inner disk cavity with an angular diameter of ~6 × 12 mas is resolved. The L-band disk consists of a bright northwestern (NW) disk region and a much fainter southeastern (SE) region. The images suggest that we are looking at the bright inner wall of the NW disk rim, which is on the far side of the disk. In the N band, only the bright NW disk region is seen. In addition to deriving the inclination and the inner disk radius, fitting the reconstructed brightness distributions via radiative transfer modelling allows one to constrain the innermost disk structure, in particular the shape of theinner disk rim.Science and Technology Facilities CouncilAgence Nationale de la Recheche (ANR)Agencia Nacional de Investigación y Desarrollo (ANID)Agencia Nacional de Investigación y Desarrollo (ANID)European Research CouncilEuropean Research CouncilEuropean Research CouncilHungarian NKFIH OTKAEuropean Research CouncilUNAM PAPIIT project IACONACyT projectFAPESPFAPESPNOVA, the Netherlands Research School for Astronom