110 research outputs found
Reshaping-induced spatiotemporal chaos in driven, damped sine-Gordon systems
Spatiotemporal chaos arising from the competition between
sine-Gordon-breather and kink-antikink-pair solitons by reshaping an ac force
is demonstrated. After introducing soliton collective coordinates, Melnikov's
method is applied to the resulting effective equation of motion to estimate the
parameter-space regions of the ac force where homoclinic bifurcations are
induced. The analysis reveals that the chaos-order threshold exhibits
sensitivity to small changes in the force shape. Computer simulations of the
sine-Gordon system show good agreement with these theoretical predictions.Comment: 11 pages, 3 figure
Nonlinear plasmonic slot waveguides
We study nonlinear modes in subwavelength slot waveguides created by a
nonlinear dielectric slab sandwiched between two metals. We present the
dispersion diagrams of the families of nonlinear plasmonic modes and reveal
that the symmetric mode undergoes the symmetry-breaking bifurcation with the
energy primarily localized near one of the interfaces. We also find that the
antisymmetric mode may split into two brunches giving birth to two families of
nonlinear antisymmetric modes.Comment: 6 pages, 5 figure
Dynamical phase diagram of the dc-driven underdamped Frenkel-Kontorova chain
Multistep dynamical phase transition from the locked to the running state of
atoms in response to a dc external force is studied by MD simulations of the
generalized Frenkel-Kontorova model in the underdamped limit. We show that the
hierarchy of transition recently reported [Braun et al, Phys. Rev. Lett. 78,
1295 (1997)] strongly depends on the value of the friction constant. A simple
phenomenological explanation for the friction dependence of the various
critical forces separating intermediate regimes is given.Comment: 12 Revtex Pages, 4 EPS figure
On the derivative of the associated Legendre function of the first kind of integer order with respect to its degree
In our recent works [R. Szmytkowski, J. Phys. A 39 (2006) 15147; corrigendum:
40 (2007) 7819; addendum: 40 (2007) 14887], we have investigated the derivative
of the Legendre function of the first kind, , with respect to its
degree . In the present work, we extend these studies and construct
several representations of the derivative of the associated Legendre function
of the first kind, , with respect to the degree , for
. At first, we establish several contour-integral
representations of . They are then
used to derive Rodrigues-type formulas for with . Next, some closed-form
expressions for are
obtained. These results are applied to find several representations, both
explicit and of the Rodrigues type, for the associated Legendre function of the
second kind of integer degree and order, ; the explicit
representations are suitable for use for numerical purposes in various regions
of the complex -plane. Finally, the derivatives
, and , all with , are evaluated in terms
of .Comment: LateX, 40 pages, 1 figure, extensive referencin
Appetite and gut hormone responses to moderate-intensity continuous exercise versus high-intensity interval exercise, in normoxic and hypoxic conditions.
This study investigated the effects of continuous moderate-intensity exercise (MIE) and high-intensity interval exercise (HIIE) in combination with short exposure to hypoxia on appetite and plasma concentrations of acylated ghrelin, peptide YY (PYY), and glucagon-like peptide-1 (GLP-1). Twelve healthy males completed four, 2.6 h trials in a random order: 1) MIE-normoxia, 2) MIE-hypoxia, 3) HIIE-normoxia, and 4) HIIE-hypoxia. Exercise took place in an environmental chamber. During MIE, participants ran for 50 min at 70% of altitude-specific maximal oxygen uptake ( 2max) and during HIIE performed 6 x 3 min running at 90% 2max interspersed with 6 x 3 min active recovery at 50% 2max with a 7 min warm-up and cool-down at 70% 2max (50 min total). In hypoxic trials, exercise was performed at a simulated altitude of 2,980 m (14.5% O2). Exercise was completed after a standardised breakfast. A second meal standardised to 30% of participants’ daily energy requirements was provided 45 min after exercise. Appetite was suppressed more in hypoxia than normoxia during exercise, post-exercise, and for the full 2.6 h trial period (linear mixed modelling, p 0.05). These findings demonstrate that short exposure to hypoxia causes suppressions in appetite and plasma acylated ghrelin concentrations. Furthermore, appetite responses to exercise do not appear to be influenced by exercise modality
Impact of Sustained Weight Loss Achieved through Roux-en-Y Gastric Bypass or a Lifestyle Intervention on Ghrelin, Obestatin, and Ghrelin/Obestatin Ratio in Morbidly Obese Patients
Unacylated ghrelin promotes adipogenesis in rodent bone marrow via ghrelin O-acyl transferase and GHS-R1a activity: evidence for target cell-induced acylation
Despite being unable to activate the cognate ghrelin receptor (GHS-R), unacylated ghrelin (UAG) possesses a unique activity spectrum that includes promoting bone marrow adipogenesis. Since a receptor mediating this action has not been identified, we re-appraised the potential interaction of UAG with GHS-R in the regulation of bone marrow adiposity. Surprisingly, the adipogenic effects of intra-bone marrow (ibm)-infused acylated ghrelin (AG) and UAG were abolished in male GHS-R-null mice. Gas chromatography showed that isolated tibial marrow adipocytes contain the medium-chain fatty acids utilised in the acylation of UAG, including octanoic acid. Additionally, immunohistochemistry and immunogold electron microscopy revealed that tibial marrow adipocytes show prominent expression of the UAG-activating enzyme ghrelin O-acyl transferase (GOAT), which is located in the membranes of lipid trafficking vesicles and in the plasma membrane. Finally, the adipogenic effect of ibm-infused UAG was completely abolished in GOAT-KO mice. Thus, the adipogenic action of exogenous UAG in tibial marrow is dependent upon acylation by GOAT and activation of GHS-R. This suggests that UAG is subject to target cell-mediated activation – a novel mechanism for manipulating hormone activity
Ablations of Ghrelin and Ghrelin Receptor Exhibit Differential Metabolic Phenotypes and Thermogenic Capacity during Aging
mice are adaptive. mice.Our data therefore suggest that GHS-R ablation activates adaptive thermogenic function(s) in BAT and increases EE, thereby enabling the retention of a lean phenotype. This is the first direct evidence that the ghrelin signaling pathway regulates fat-burning BAT to affect energy balance during aging. This regulation is likely mediated through an as-yet-unidentified new ligand of GHS-R
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