Valor compartido en la industria de producción de cemento en el Perú

La presente investigación identificó la situación del valor compartido en la industria de producción de cemento en el Perú, con el fin de saber hasta dónde se conoce y aplica en dicho sector la teoría de valor compartido y si ésta se aplica en el desarrollo de las estrategias internas de la empresa. Se empleó una encuesta con preguntas cerradas sobre valor compartido proporcionada por la Coordinación de Tesis, la cual incluyó cinco secciones: (a) información de la empresa, (b) conocimiento sobre creación de valor compartido, (c) información sobre gobernanza y transparencia, (d) creación de valor compartido y (e) evaluación de iniciativas de impacto común. Como resultado de la investigación, se identificó que las empresas de la industria de producción de cemento en el Perú incluidas en el estudio desarrollan actividades que están relacionadas al impacto positivo en la sociedad con orientación a la búsqueda de beneficios de licencia social e imagen. De manera paralela, parte de dichas actividades también buscaban generar un beneficio económico para la organización, ya sea a través de la mejora en su cadena de valor, el desarrollo de nuevos productos y mercados o del fomento de la creación de clústeres de apoyo. Finalmente, con la presente investigación se identificó que a pesar de desarrollar actividades que comparten los principios del modelo de creación de valor compartido las empresas no lo declaraban o mencionan en sus reportes, lo cual daba un mayor grado de exposición a sus modelos de responsabilidad social empresarial y a la sustentabilidad de sus acciones que a los beneficios obtenidos a nivel interno por su aplicación; aun cuando con ello tenían una oportunidad de integrar el modelo de creación de valor compartido en su estrategia de desarrolloThe present investigation identifies the situation of shared value in the cement production industry in Peru, in order to know the extent to which the shared value theory is known and applied in this sector and whether it is applied in the development of strategies of the company. A closed questionnaire on shared value provided by the Thesis Coordination was used, which included five sections: a) company information, b) knowledge about shared value creation, c) information on governance and transparency, d) creation of Shared value and (e) evaluation of common impact initiatives. As a result of the investigation, it was identified that the companies of the cement production industry in Peru included in this investigation develop activities that are related to the positive impact in the society with orientation to the search of benefits of social license and image; And in parallel, part of these activities also seek to generate an economic benefit for the organization, either through the improvement in its value chain, the development of new markets or products or encouraging the creation of support clusters. Finally, the present study identified that despite the development of activities that share the principles of the shared value creation model, companies do not state it or mention it in their reports, thus giving a greater degree of exposure to their models of social responsibility Business and the sustainability of its actions, than benefits they have obtained internally for their application; thus having an opportunity to integrate the model of shared value creation in its development strategyTesi

Effect of new generation enzymes addition on the physical, viscoelastic and textural properties of traditional Mexican sweet bread

Se estudio el efecto de la adición de enzimas en las propiedades viscosas y texturales de un pan tradicional mexicano.The effect of adding new generation enzymes (0.25, 0.5, 0.75, and 1.0% w/w) on traditional Mexican sweet bread physical, viscoelastic (elastic and plastic work) and textural properties was studied. Physical properties as weight lost, pore uniformity, color, etc., improved with enzyme addition. Viscoelasticity properties were analyzed by uniaxial compression test under small strain, showing that the use of small enzyme fractions (~0.25-0.5% w/w) are enough to enhance mechanical behavior (higher elastic work) and cohesiveness and resilience parameters after four storage days. This trend suggests a mechanism related to pore distribution and an equilibrium crust-crumb that lead to improved bread freshness over storage period. Overall, results indicated that relatively low enzyme concentrations can led to important improvements in the fabrication process of traditional Mexican sweet bread. The proposed enzyme concentrations are as small as 0.25-0.3% w/w, corresponding to approximately half the percentage of the amount frequently used in industrial bread production

Sindrome de hiperinmunoglobulinemia e reporte de un caso

Presentamos el caso de una paciente mujer de 17 meses de edad, con cuadro respiratorio de 3 semanas de evolución; asociado a muguet oral, lesiones papuloeritematosa en rostro, cuero cabelludo y genitales con candidiasis sobreagregada. En TEM Torácica se informa neumonía complicada con empiema; se realizó toracocentésis obteniéndose secreción purulenta con cultivo positivo para Staphylococcus aureus Los resultados de Inmunoglobulinas evidenciaron Ig E=1353mg/dL, con un puntaje de 56 en los Criterios de Grimbacher confirmando el diagnóstico de síndrome de Hiper Inmunoglobulina E. El síndrome de Hiper Inmunoglobulina E es una inmunodeficiencia primaria infrecuente de etiología desconocida, con afectación multisistémica, caracterizada por infecciones cutáneas recidivantes, neumonías severas y niveles elevados de inmunoglobulina E. Fue descrito por primera vez en 1966, su incidencia es 1:500 000 y no existen diferencias respecto a la raza o al sexo. Su diagnóstico clínico se establece a través de los Criterios de Grimbacher

The Neuroprotector Benzothiazepine CGP37157 Extends Lifespan in C. elegans Worms

The benzothiazepine CGP37157 has shown neuroprotective effects in several in vitro models of excitotoxicity involving dysregulation of intracellular Ca2+ homeostasis. Although its mechanism of neuroprotection is unclear, it is probably related with some of its effects on Ca2+ homeostasis. CGP37157 is a well-known inhibitor of the mitochondrial Na+/Ca2+ exchanger (mNCX). However, it is not very specific and also blocks several other Ca2+ channels and transporters, including voltage-gated Ca2+ channels, plasma membrane Na+/Ca2+ exchanger and the Ca2+ homeostasis modulator 1 channel (CALHM1). In the present work, we have studied if CGP37157 could also induce changes in life expectancy. We now report that CGP37157 extends C. elegans lifespan by 10%–15% with a bell-shaped concentration-response, with high concentrations producing no effect. The effect was even larger (25% increase in life expectancy) in worms fed with heat-inactivated bacteria. The worm CGP37157 concentration producing maximum effect was measured by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) and was close to the IC50 for inhibition of the Na+/Ca2+ exchanger. CGP37157 also extended the lifespan in eat-2 mutants (a model for caloric restriction), suggesting that caloric restriction is not involved in the mechanism of lifespan extension. Actually, CGP37157 produced no effect in mutants of the TOR pathway (daf15/unc24) or the insulin/insulin-like growth factor-1 (IGF-1) pathway (daf-2), indicating that the effect involves these pathways. Moreover, CGP37157 was also ineffective in nuo-6 mutants, which have a defect in the mitochondrial respiratory chain complex I. Since it has been described that neuroprotection by this compound in cell cultures is abolished by mitochondrial inhibitors, this suggests that life extension in C. elegans and neuroprotection in cell cultures may share a similar mechanism involving mitochondria

Acute Lymphoblastic Leukemia in Adolescents and Young Adults

When diagnosed with ALL the age group between 18 and 45 years old (AYA, adolescents and young adults) do not have the good prognosis factors generally observed in children with this diagnosis. For a long time, it was undetermined whether they should be treated with continuous and sustained chemotherapy as children or whether receive sustained chemotherapy, but with longer rest periods like old adults. The medical care of adolescents and young adults with neoplastic diseases, grouped between 15 and 45 years of age, became an emerging research field of treatment in hematological diseases. Outcomes have asses complete response disease-free survival, and overall survival as markers of response, with very poor results reported. Relevant challenges have been identified in the AYA group with ALL that have drawn attention to the need to increase research in this area, particularly in the care of the population under 45 years of age with hematological malignancies

Childhood acute leukemias are frequent in Mexico City: descriptive epidemiology

<p>Abstract</p> <p>Background</p> <p>Worldwide, acute leukemia is the most common type of childhood cancer. It is particularly common in the Hispanic populations residing in the United States, Costa Rica, and Mexico City. The objective of this study was to determine the incidence of acute leukemia in children who were diagnosed and treated in public hospitals in Mexico City.</p> <p>Methods</p> <p>Included in this study were those children, under 15 years of age and residents of Mexico City, who were diagnosed in 2006 and 2007 with leukemia, as determined by using the International Classification of Childhood Cancer. The average annual incidence rates (AAIR), and the standardized average annual incidence rates (SAAIR) per million children were calculated. We calculated crude, age- and sex-specific incidence rates and adjusted for age by the direct method with the world population as standard. We determined if there were a correlation between the incidence of acute leukemias in the various boroughs of Mexico City and either the number of agricultural hectares, the average number of persons per household, or the municipal human development index for Mexico (used as a reference of socio-economic level).</p> <p>Results</p> <p>Although a total of 610 new cases of leukemia were registered during 2006-2007, only 228 fit the criteria for inclusion in this study. The overall SAAIR was 57.6 per million children (95% CI, 46.9-68.3); acute lymphoblastic leukemia (ALL) was the most frequent type of leukemia, constituting 85.1% of the cases (SAAIR: 49.5 per million), followed by acute myeloblastic leukemia at 12.3% (SAAIR: 6.9 per million), and chronic myeloid leukemia at 1.7% (SAAIR: 0.9 per million). The 1-4 years age group had the highest SAAIR for ALL (77.7 per million). For cases of ALL, 73.2% had precursor B-cell immunophenotype (SAAIR: 35.8 per million) and 12.4% had T-cell immunophenotype (SAAIR 6.3 per million). The peak ages for ALL were 2-6 years and 8-10 years. More than half the children (58.8%) were classified as high risk. There was a positive correlation between the average number of persons per household and the incidence of the pre-B immunophenotype (Pearson's r, 0.789; P = 0.02).</p> <p>Conclusions</p> <p>The frequency of ALL in Mexico City is among the highest in the world, similar to those found for Hispanics in the United States and in Costa Rica.</p

Design and implementation of the AMIGA embedded system for data acquisition

The Auger Muon Infill Ground Array (AMIGA) is part of the AugerPrime upgrade of the Pierre Auger Observatory. It consists of particle counters buried 2.3 m underground next to the water-Cherenkov stations that form the 23.5 km$^2$ large infilled array. The reduced distance between detectors in this denser area allows the lowering of the energy threshold for primary cosmic ray reconstruction down to about 10$^{17}$ eV. At the depth of 2.3 m the electromagnetic component of cosmic ray showers is almost entirely absorbed so that the buried scintillators provide an independent and direct measurement of the air showers muon content. This work describes the design and implementation of the AMIGA embedded system, which provides centralized control, data acquisition and environment monitoring to its detectors. The presented system was firstly tested in the engineering array phase ended in 2017, and lately selected as the final design to be installed in all new detectors of the production phase. The system was proven to be robust and reliable and has worked in a stable manner since its first deployment.Comment: Accepted for publication at JINST. Published version, 34 pages, 15 figures, 4 table