306 research outputs found

    Ohio and Michigan Law on Postemployment Covenants Not to Compete

    Get PDF

    Digital forest information platform as service innovation : Finnish Metsaan. fi service use, users and utilisation

    Get PDF
    Abundance of information characterises decision-making about forest use. This challenges forest owners. Digitalisation and diverse e-services may enhance the delivery of forest resource information and decision support. However, little is known on how e-services engage forest owners. This study explores the Finnish state-funded Metsaan.fi e-service portal as a service innovation. We use web-based survey data about forest owners' views on aforementioned e-service (N = 5170) and register data about Finnish forest owners. The identified factors explain the respondents' activity in using the service. Theories of innovation diffusion and e-service quality framed the content analysis of the open-ended questions of the survey. According to the quantitative analysis, owners with timber production objectives and multi-objective owners were the most active users. Forest owners who were compliant with the service's recommendations of silviculture and harvesting operations, used the service actively. This implies that these forest owners had found the service useful. The qualitative analysis shows that independence from time and place and the ease-of-use make the service more inviting. The lack of forest inventory data or its perceived low quality detract forest owners from using it. Many forest owners expect the service to replace forest management plans as decision support tool but the information content there does not fully fulfil those expectations. The study produced knowledge for developing further the online platform and its services. Furthermore, it created understanding about e-government services in the management of natural resources. Specifically, the results argue for noticing attitudinal patterns of intended users when designing governmental e-services. Further research is suggested to integrate innovation adoption theory and service research theory to dig deeper into the value creation and service needs of different user groups.Peer reviewe

    The nasal cavity microbiota of healthy adults

    Full text link
    Abstract Background The microbiota of the nares has been widely studied. However, relatively few studies have investigated the microbiota of the nasal cavity posterior to the nares. This distinct environment has the potential to contain a distinct microbiota and play an important role in health. Results We obtained 35,142 high-quality bacterial 16S rRNA-encoding gene sequence reads from the nasal cavity and oral cavity (the dorsum of the tongue and the buccal mucosa) of 12 healthy adult humans and deposited these data in the Sequence Read Archive (SRA) of the National Center for Biotechnology Information (NCBI) (Bioproject: PRJNA248297). In our initial analysis, we compared the bacterial communities of the nasal cavity and the oral cavity from ten of these subjects. The nasal cavity bacterial communities were dominated by Actinobacteria, Firmicutes, and Proteobacteria and were statistically distinct from those on the tongue and buccal mucosa. For example, the same Staphylococcaceae operational taxonomic unit (OTU) was present in all of the nasal cavity samples, comprising up to 55% of the community, but Staphylococcaceae was comparatively uncommon in the oral cavity. Conclusions There are clear differences between nasal cavity microbiota and oral cavity microbiota in healthy adults. This study expands our knowledge of the nasal cavity microbiota and the relationship between the microbiota of the nasal and oral cavities.http://deepblue.lib.umich.edu/bitstream/2027.42/109547/1/40168_2014_Article_56.pd

    The CAPM is Not Dead: It Works Better for Average Daily Returns

    Get PDF
    In a series of papers, Fama and French showed that the CAPM failed to explain U.S. stock returns. Subsequently, they declared the CAPM dead. In its place, they proposed a number of different factors to better explain stock returns. Given that Sharpe received the Nobel Prize in Economics for the CAPM, their conclusion that it is dead is worth further investigation. This paper revisits cross-sectional tests of the Capital Asset Pricing Model (CAPM). To mitigate problems with noise in realized stock return series, we use a smoothed data series of average daily returns per month. Based on U.S. stock returns from 1965 to 2015, we find that, confirming Fama and French, beta is not priced for realized monthly returns. However, contrary to their findings, when we use average daily returns per month, we find that beta is significantly priced for average daily returns in equal-weighted stock portfolios. Further analyses reveal that popular factors proposed by Fama and French and others are more significantly priced for average daily returns also. Given that the CAPM is better supported by average daily returns per month than realized monthly returns, we conclude that it is not dead

    Is There a Difference in Staging and Treatment of Head and Neck Squamous Cell Tumors Between Tertiary Care and Community‐Based Institutions?

    Full text link
    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/145574/1/lio2178.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/145574/2/lio2178_am.pd

    Implementation of Primary Care Pandemic Plan: Respiratory Clinic Model

    Full text link
    Implementation articleObjective: In an effort to keep our patients and staff safe while providing necessary care, we implemented phases 2 and 3 of the Primary Care Pandemic Plan as described by Krist et al.1 We consolidated clinics, we converted nearly all visits to virtual visits and separated the remaining face to face visits into sick and well patient cohorts.https://deepblue.lib.umich.edu/bitstream/2027.42/154742/1/Respiratory clinic for Amb Care during COVID_ revised_FINAL.pdfDescription of Respiratory clinic for Amb Care during COVID_ revised_FINAL.pdf : Main Articl

    The value of a Feasibility Study into long-term Macrolide therapy in Chronic Rhinosinusitis

    Get PDF
    Objectives:There is currently conflicting level 1 evidence in the use of long-term antibiotics for chronic rhinosinusitis without nasal polyps. The primary aim of this feasibility study was to optimise future randomised trial design by assessing recruitment and retention of patients alongside providing preliminary data on symptomatic control.  Design: Prospective, multi-centre feasibility (cohort) study with all patients receiving macrolide therapy for 12-weeks and a further subsequent 12-week follow-up. Participants received a 12-week course of Clarithromycin 250mg alongside twice daily topical Mometasone and nasal douching. Primary outcomes focused on recruitment, retention and compliance. Clinical and quality-of-life outcomes measures were also recorded.  Setting: Patients were prospectively recruited from 6 UK outpatient clinics.  Participants: Adult patients with chronic rhinosinusitis without nasal polyps and no prior endoscopic sinus surgery underwent baseline assessment and then follow-up at 3 and 6 months.  Main outcome measures: Six-month recruitment and retention data.  Results: Over 13 months, 55 adults were recruited from 5 centres. Four patients declined participation. 75% of patients were retained within the study. Dropouts included 1 medication contraindication, 3 unable to tolerate medication, 10 not attending full follow-up. Sino Nasal Outcome Test-22 and endoscopic scores showed statistically significant improvement. No other clinical or quality-of -life assessment improvements were seen.  Conclusion: Retention and recruitment to a trial using long-term Clarithromycin to treat chronic rhinosinusitis without nasal polyps is achievable and this data will support a future Randomised Controlled Trial. The study provides vital insight into trial design thus informing UK research networks and rhinology researchers internationally

    Canadian guidelines for rhinosinusitis: practical tools for the busy clinician

    Get PDF
    Acute bacterial rhinosinusitis (ABRS) and chronic rhinosinusitis (CRS) frequently present in clinical practice. Guidelines for management of these conditions have been published extensively in the past. However, a set of guidelines that addressed issues specific to the Canadian environment while offering clear guidance for first-line clinicians was needed, and resulted in the recent publication of Canadian clinical practice guidelines for ABRS and CRS. In addition to addressing issues specific to Canadian physicians, the presented guidelines are applicable internationally, and offer single algorithms for the diagnosis and management of ABRS and CRS, as well as expert opinion in areas that do not have an extensive evidence base. This commentary presents major points from the guidelines, as well as the intended impact of the guidelines on clinical practice
    corecore