The way ahead for medicine with the genomic code

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Statistical correlation analysis for comparing vibration data from test and analysis

A theory was developed to compare vibration modes obtained by NASTRAN analysis with those obtained experimentally. Because many more analytical modes can be obtained than experimental modes, the analytical set was treated as expansion functions for putting both sources in comparative form. The dimensional symmetry was developed for three general cases: nonsymmetric whole model compared with a nonsymmetric whole structural test, symmetric analytical portion compared with a symmetric experimental portion, and analytical symmetric portion with a whole experimental test. The theory was coded and a statistical correlation program was installed as a utility. The theory is established with small classical structures

Statistical correlation of structural mode shapes from test measurements and NASTRAN analytical values

The software and procedures of a system of programs used to generate a report of the statistical correlation between NASTRAN modal analysis results and physical tests results from modal surveys are described. Topics discussed include: a mathematical description of statistical correlation, a user's guide for generating a statistical correlation report, a programmer's guide describing the organization and functions of individual programs leading to a statistical correlation report, and a set of examples including complete listings of programs, and input and output data

Design and implementation of a compliant robot with force feedback and strategy planning software

Force-feedback robotics techniques are being developed for automated precision assembly and servicing of NASA space flight equipment. Design and implementation of a prototype robot which provides compliance and monitors forces is in progress. Computer software to specify assembly steps and makes force feedback adjustments during assembly are coded and tested for three generically different precision mating problems. A model program demonstrates that a suitably autonomous robot can plan its own strategy

Robust and inexpensive equipment design for polymerase chain reaction detection of sequence mutations Cystic fibrosis in a mother and 2 children analysed

Every polymerase chain reaction (PCR) requires use of a temperature cycler for about 3 hours. Since there are many diagnostic tests using this technology, it is important that robust but inexpensive machinery is available. Such a standalone machine has been designed and used to analyse an interesting family in which another and her 2 children were diagnosed as having cystic fibrosis

A new neurosurgical tool incorporating differential geometry and cellular automata techniques

Using optical coherence imaging, it is possible to visualize seizure progression intraoperatively. However, it is difficult to pinpoint an exact epileptic focus. This is crucial in attempts to minimize the amount of resection necessary during surgical therapeutic interventions for epilepsy and is typically done approximately from visual inspection of optical coherence imaging stills. In this paper, we create an algorithm with the potential to pinpoint the source of a seizure from an optical coherence imaging still. To accomplish this, a grid is overlaid on optical coherence imaging stills. This then serves as a grid for a two-dimensional cellular automation. Each cell is associated with a Riemannian curvature tensor representing the curvature of the brain's surface in all directions for a cell. Cells which overlay portions of the image which show neurons that are firing are considered "depolarized"

Measurable, Nonleavable Gambling Problems

1 online resource (PDF, 22 pages

Concept for a Large Scalable Space Telescope: In-Space Assembly

We present a conceptual design for a scalable (10-50 meter segmented filled-aperture) space observatory operating at UV-optical-near infrared wavelengths. This telescope is designed for assembly in space by robots, astronauts or a combination of the two, as envisioned in NASA s Vision for Space Exploration. Our operations concept for this-space telescope provides for assembly and check-out in an Earth Moon L2 (EML2) orbit, and transport to a Sun-Earth L2 (SEL2) orbit for science operations and routine servicing, with return to EML2 for major servicing. We have developed and analyzed initial designs for the optical, structural, thermal and attitude control systems for a 30-m aperture space telescope. We further describe how the separate components are packaged for launch by heavy lift vehicle(s) and the approach for the robot assembly of the telescope from these components

How did smokers respond to standardised cigarette packaging with new, larger health warnings in the United Kingdom during the transition period? A cross-sectional online survey

Introduction: In the United Kingdom, standardised packaging for cigarettes was phased in between May 2016 and May 2017. We assessed whether there was an association between using standardised packs and warning salience, thoughts about the risks of smoking, thoughts about quitting, and awareness and use of stop-smoking websites. Methods: We conducted a cross-sectional online survey with current smokers aged 16 and over (N = 1865) recruited in two regions of England between February-April 2017, when both standardised and fully-branded packs were on the market. Participants were asked about use of standardised packs, warning salience (noticing, reading closely), and whether the packs they were using increased thoughts of the risks of smoking and quitting. They were also asked about awareness of stop-smoking websites, source of awareness (including warnings on packs), and whether they had visited a stop-smoking website. Results: Most participants reported currently using standardised packs (76.4%), 9.3% were not currently using them but had previously used them, and 14.3% had never used them. Compared with never users, current users were more likely to have noticed the warnings on packs often/very often (AOR (95%CI) = 2.76 (2.10, 3.63)), read them closely often/very often (AOR(95%CI) = 2.16 (1.51, 3.10)), thought somewhat/a lot about the health risks of smoking (AOR(95%CI) = 1.92 (1.38, 2.68)), and thought somewhat/a lot about quitting (AOR(95%CI) = 1.90 (1.30, 2.77)). They were also more likely to have noticed a stop-smoking website on packs. Conclusions: Consistent with the broad objectives of standardised packaging, we found that it was associated with increased warning salience and thoughts about risks and quittingOutput Status: Forthcoming/Available Onlin