Estudio comparativo de la cavidad de acceso radicular en conductos curvos con limas de níquel-titanio y taladros de acero inoxidable

El propósito de este estudio fue comparar la cantidad de dentina radicular removida y evaluar el mantenimiento de la forma del conducto tras la instrumentación de los dos tercios coronarios radiculares, utilizando instrumentos de acero inoxidable (taladros de Gates Glidden) y de níqueltitanio (limas GT Flare y limas Orifice Shaper). Un total de 42 dientes humanos extraídos con conductos radiculares curvos fueron divididos en tres grupos. Los conductos se instrumentaron mecánicamente usando taladros de Gates Glidden, limas Orifice Shaper o GT Flare con la técnica corono-apical. Este estudio se realizó siguiendo la técnica de Bramante modificada. Las secciones transversales de cada conducto fueron efectuadas a tres niveles horizontales diferentes (a 2, 4 y 6mm de su inicio en la cámara). Antes y después de la instrumentación fueron observados y fotografiados para luego ser medidos. A cada nivel se valoraron dos parámetros, el mantenimiento de la forma original del conducto y la cantidad de dentina removida. El análisis estadístico reveló que existían diferencias estadísticamente significativas (p<0,05) a nivel de los cortes a 4 y 6 mm en la cara interna del conducto; mientras que la preparación del mismo más prevalente fue excéntrica sin ensanchar todas las paredes del conducto

CAFE-GAN: Arbitrary Face Attribute Editing with Complementary Attention Feature

The goal of face attribute editing is altering a facial image according to given target attributes such as hair color, mustache, gender, etc. It belongs to the image-to-image domain transfer problem with a set of attributes considered as a distinctive domain. There have been some works in multi-domain transfer problem focusing on facial attribute editing employing Generative Adversarial Network (GAN). These methods have reported some successes but they also result in unintended changes in facial regions - meaning the generator alters regions unrelated to the specified attributes. To address this unintended altering problem, we propose a novel GAN model which is designed to edit only the parts of a face pertinent to the target attributes by the concept of Complementary Attention Feature (CAFE). CAFE identifies the facial regions to be transformed by considering both target attributes as well as complementary attributes, which we define as those attributes absent in the input facial image. In addition, we introduce a complementary feature matching to help in training the generator for utilizing the spatial information of attributes. Effectiveness of the proposed method is demonstrated by analysis and comparison study with state-of-the-art methods

Hipoplasia cerebelar en el gato

En el presente trabajo, y a propósito de un caso clínico, se efectúa una revisión completa de la hipoplasia cerebelar en el gato, incluyendo la anatomía, embriología y función del cerebelo, el cuadro clínico y lesional que se presenta, así como el diagnóstico, el posible tratamiento y la prevención.In this paper, on a case, a complete review about cerebellar hypoplasia in cat is made. It includes cerebellum anatomy, embriology and function, clinical findings, lesions and diagnosis, possible treatment and the prevention

Gene expression profiling en association with prion-related lesions in the medulla oblongata of symptomatic natural scrapie animals.

The pathogenesis of natural scrapie and other prion diseases remains unclear. Examining transcriptome variations in infected versus control animals may highlight new genes potentially involved in some of the molecular mechanisms of prion-induced pathology. The aim of this work was to identify disease-associated alterations in the gene expression profiles of the caudal medulla oblongata (MO) in sheep presenting the symptomatic phase of natural scrapie. The gene expression patterns in the MO from 7 sheep that had been naturally infected with scrapie were compared with 6 controls using a Central Veterinary Institute (CVI) custom designed 4×44K microarray. The microarray consisted of a probe set on the previously sequenced ovine tissue library by CVI and was supplemented with all of the Ovis aries transcripts that are currently publicly available. Over 350 probe sets displayed greater than 2-fold changes in expression. We identified 148 genes from these probes, many of which encode proteins that are involved in the immune response, ion transport, cell adhesion, and transcription. Our results confirm previously published gene expression changes that were observed in murine models with induced scrapie. Moreover, we have identified new genes that exhibit differential expression in scrapie and could be involved in prion neuropathology. Finally, we have investigated the relationship between gene expression profiles and the appearance of the main scrapie-related lesions, including prion protein deposition, gliosis and spongiosis. In this context, the potential impacts of these gene expression changes in the MO on scrapie development are discussed

Antiviral activity of maca (Lepidium meyenii) against human influenza virus

Objective: To investigate antiviral activity of maca to reduce viral load in kidney (MDCK) cells infected with influenza type A and B viruses (Flu-A and MFalud-inB-, Dreasrpbeyc ctiavneilny)e. Methods: Maca were extracted with methanol (1:2, v/v). The cell viability and toxicity of the eaxgtariancstts Fwluer-eA e avnaldu aFtleud- oBn v MirDusCeKs cwealsls a usssianyge dm uetshinogd aM TteTs ta sfosar yd. eAtenrtmiviinrainl ga ctthiev itiyn hoifb citoimonp oouf nthdes cytopathic effect on cell culture and multiplex RT-PCR. Results: The methanol extract of maca showed low cytotoxicity and inhibited influenza-induced cytopathic effect significantly, while viral load was reduced via inhibition of viral growth in MDCK infected cells. Maca contains potent inhibitors of Flu-A and Flu-B with a selectivity index [cytotoxic concentration 50%/IC50] of 157.4 and 110.5, respectively. Conclusions: In vitro assays demonstrated that maca has antiviral activity not only against Flu-A (like most antiviral agents) but also Flu-B viruses, providing remarkable therapeutic benefits.Financial support of this study was provided by AECID grants (PCI: C/033641/10) and AGAUR (MAT2009-11503, MAT2012-36205, 2009SGR-1208). JDVM support was provided by 1st Concurso Incentivo a la Investigación de la Universidad Peruana de Ciencias Aplicadas, Lima, Peru.Revisión por pare

Toward Fine-grained Facial Expression Manipulation

Facial expression manipulation aims at editing facial expression with a given condition. Previous methods edit an input image under the guidance of a discrete emotion label or absolute condition (e.g., facial action units) to possess the desired expression. However, these methods either suffer from changing condition-irrelevant regions or are inefficient for fine-grained editing. In this study, we take these two objectives into consideration and propose a novel method. First, we replace continuous absolute condition with relative condition, specifically, relative action units. With relative action units, the generator learns to only transform regions of interest which are specified by non-zero-valued relative AUs. Second, our generator is built on U-Net but strengthened by Multi-Scale Feature Fusion (MSF) mechanism for high-quality expression editing purposes. Extensive experiments on both quantitative and qualitative evaluation demonstrate the improvements of our proposed approach compared to the state-of-the-art expression editing methods. Code is available at \url{https://github.com/junleen/Expression-manipulator}

Nocardiosis en un perro

Se describe un caso de nocardiosis en un perro. Se presentan y discuten el cuadro clínico y los hallazgos microbiológicos, ana tomo patológicos e histopatológicos.A case of canine nocardiosis is described. Its clinical, microbiological, pathological and histopathological findings are presented and discussed