Recanalization and rupture of a brain aneurysm completely occluded with a LEO stent nine years ago

We describe what is to our knowledge the first case of aneurysm regrowth and rupture after the nine years, of a complete occlusion of an aneurysm of the left middle cerebral treated of Leo Plus StentS

A miniaturized 3d heat flux sensor to characterize heat transfer in regolith of planets and small bodies

The objective of this work is to present the first analytical and experimental results obtained with a 3D heat flux sensor for planetary regolith. The proposed structure, a sphere divided in four sectors, is sensible to heat flow magnitude and angle. Each sector includes a platinum resistor that is used both to sense its temperature and provide heating power. By operating the sectors at constant temperature, the sensor gives a response that is proportional to the heat flux vector in the regolith. The response of the sensor is therefore independent of the thermal conductivity of the regolith. A complete analytical solution of the response of the sensor is presented. The sensor may be used to provide information on the instantaneous local thermal environment surrounding a lander in planetary exploration or in small bodies like asteroids. To the best knowledge of the authors, this is the first sensor capable of measuring local 3D heat fluxThis work was supported in part by the Spanish Ministerio de Economía y Competividad under Projects RTI2018-098728-B-C31 and RTI2018-098728-B-C33Peer ReviewedPostprint (published version

Importancia de la embolización preoperatoria en el tratamiento del quiste óseo aneurismático: Presentación de un caso clínico

Se describe el tratamiento de un quiste óseo aneurismático localizado en el raquis dorsal, en un niño de 8 años de edad. El quiste óseo aneurismático es una lesión benigna y a menudo extremadamente vascular. En la columna puede causar extensa destrucción ósea y compromiso de las estructuras neurales. Se demuestra el valor de la embolización preoperatoria reduciendo la vascularización y permitiendo su extirpación quirúrgica total.I n this report, th e managemen t o f a n aneurysma l bon e cyst i n th e thoraci c spin e o f an 8 year s ol d bo y is described . Aneurysma l bon e is a histologicall y benig n lesio n tha t is ofte n extremel y vascular . I n th e spine , it ca n caus e extensiv e bon e destructio n an d compress neura l structures. Th e valu e o f preoperativ e embo - lizatio n t o reduc e vascularity , allowin g tota l excisio n is demonstrated

A CubeSAT payload for in-situ monitoring of pentacene degradation due to atomic oxygen etching in LEO

This paper reports and discusses the design and ground tests of a CubeSat payload which allows to measure, in-situ and in real time, the degradation of a polymer of electronic interest due to atomic oxygen etching in LEO. It provides real-time information on how the degradation occurs, eliminating the need to work with samples recovered once the mission has finished. The polymer, TIPS-Pentacene, is deposited on the surface of a microelectromechanical (MEMS) cantilever, which works as a resonator embedded in a Pulsed Digital Oscillator circuit. The mass losses in the polymer due to atomic oxygen corrosion produce variations in the resonant frequency of the MEMS, which is continuously sensed by the circuit and transmitted to the ground. This way, polymer mass losses around 10-12 kg can be detected during the mission. The payload is a part of the 3Cat-1 mission, a nano-satellite aimed at carrying out several scientific experiments.Peer ReviewedPostprint (author's final draft

Temperature-Induced Changes in Reperfused Stroke: Inflammatory and Thrombolytic Biomarkers

Although hyperthermia is associated with poor outcomes in ischaemic stroke (IS), some studies indicate that high body temperature may benefit reperfusion therapies. We assessed the association of temperature with effective reperfusion (defined as a reduction of ≥8 points in the National Institute of Health Stroke Scale (NIHSS) within the first 24 h) and poor outcome (modified Rankin Scale (mRS) > 2) in 875 retrospectively-included IS patients. We also studied the influence of temperature on thrombolytic (cellular fibronectin (cFn); matrix metalloproteinase 9 (MMP-9)) and inflammatory biomarkers (tumour necrosis factor-alpha (TNF-α), interleukin 6 (IL-6)) and their relationship with effective reperfusion. Our results showed that a higher temperature at 24 but not 6 h after stroke was associated with failed reperfusion (OR: 0.373, p = 0.001), poor outcome (OR: 2.190, p = 0.005) and higher IL-6 levels (OR: 0.958, p 37.5 °C at 24 h, but not at 6 h after stroke, is correlated with reperfusion failure, poor clinical outcome, and infarct size. Mild hyperthermia (36.5–37.5 °C) in the first 6 h window might benefit drug reperfusion therapies by promoting clot lysisThis study was partially supported by grants from the Spanish Ministry of Science and Innovation (SAF2017-84267-R), Xunta de Galicia (Consellería Educación: IN607A2018/3), Instituto de Salud Carlos III (ISCIII) (PI17/00540 and PI17/01103), Spanish Research Network on Cerebrovascular Diseases RETICS-INVICTUS PLUS (RD16/0019), and by the European Union FEDER program. Furthermore, Tomás. Sobrino (CPII17/00027) and Francisco Campos (CPII19/00020) are recipients of research contracts from the Miguel Servet Program of Instituto de Salud Carlos III. María Pérez-Mato is a Sara Borrell Researcher (CD19/00033)S

COVID-19 and Neurointerventional Service Worldwide: A Survey of the European Society of Minimally Invasive Neurological Therapy (ESMINT), the Society of NeuroInterventional Surgery (SNIS), the Sociedad Iberolatinoamericana De Neuroradiologia Diagnostica Y Terapeutica (SILAN), the Society of Vascular and Interventional Neurology (SVIN), and the World Federation of Interventional and Therapeutic Neuroradiology (WFITN)

BACKGROUND This survey was focused on the provision of neurointerventional services, the current practices of managing patients under COVID-19 conditions, and the expectations for the future. METHODS Invitations for this survey were sent out as a collaborative effort of the European Society of Minimally Invasive Neurological Therapy (ESMINT), the Society of NeuroInterventional Surgery (SNIS), the Sociedad Iberolatinoamericana de Neuroradiologia Diagnostica y Terapeutica (SILAN), the Society of Vascular and Interventional Neurology (SVIN), and the World Federation of Interventional and Therapeutic Neuroradiology (WFITN). RESULTS Overall, 475 participants from 61 countries responded (six from Africa (1%), 81 from Asia (17%), 156 from Europe (33%), 53 from Latin America (11%), and 172 from North America (11%)). The majority of participants (96%) reported being able to provide emergency services, though 26% of these reported limited resources. A decrease in emergency procedures was reported by 69% of participants (52% in ischemic and hemorrhagic stroke, 11% ischemic, and 6% hemorrhagic stroke alone). Only 4% reported an increase in emergency cases. The emerging need for social distancing and the rapid adoption of remote communication was reflected in the interest in establishing case discussion forums (43%), general online forums (37%), and access to angio video streaming for live mentoring and support (33%). CONCLUSION Neurointerventional emergency services are available in almost all centers, while the number of emergency patients is markedly decreased. Half of the participants have abandoned neurointerventions in non-emergent situations. There are considerable variations in the management of neurointerventions and in the expectations for the future

Spherical probe for the thermophysical characterization of regoliths for planetary exploration using frequency methods

© 2022 Elsevier. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/The objective of this paper is to analyse the capability of a spherical thermoprobe, recently proposed as a 3D heat flux sensor for regoliths, and additionally to characterize the thermophysical properties of regoliths. The sensor is based on the spherical structure of a Mars wind sensor. The characterization is carried out using frequency methods. Extensive experimental results have been obtained with eight regolith simulants made of glass microbeads. Errors in thermal conductivity and diffusivity are smaller than ± 7%, for these simulants.Funded in part by MICINN, grants no. RTI2018-098728-B-C33 and PID2021-126719OB-C42, and ESA contract 4000128070/19/NL/KML for the MiniPINS study.Peer ReviewedPostprint (published version

The Mars Environmental Dynamics Analyzer, MEDA: a suite of environmental sensors for the Mars 2020 mission

This is a post-peer-review, pre-copyedit version of an article published in Space science reviews. The final authenticated version is available online at: http://dx.doi.org/10.1007/s11214-021-00816-9NASA’s Mars 2020 (M2020) rover mission includes a suite of sensors to monitor current environmental conditions near the surface of Mars and to constrain bulk aerosol properties from changes in atmospheric radiation at the surface. The Mars Environmental Dynamics Analyzer (MEDA) consists of a set of meteorological sensors including wind sensor, a barometer, a relative humidity sensor, a set of 5 thermocouples to measure atmospheric temperature at ~1.5 m and ~0.5 m above the surface, a set of thermopiles to characterize the thermal IR brightness temperatures of the surface and the lower atmosphere. MEDA adds a radiation and dust sensor to monitor the optical atmospheric properties that can be used to infer bulk aerosol physical properties such as particle size distribution, non-sphericity, and concentration. The MEDA package and its scientific purpose are described in this document as well as how it responded to the calibration tests and how it helps prepare for the human exploration of Mars. A comparison is also presented to previous environmental monitoring payloads landed on Mars on the Viking, Pathfinder, Phoenix, MSL, and InSight spacecraft.Peer ReviewedPostprint (published version

The diverse meteorology of Jezero crater over the first 250 sols of Perseverance on Mars

NASA’s Perseverance rover’s Mars Environmental Dynamics Analyzer is collecting data at Jezero crater, characterizing the physical processes in the lowest layer of the Martian atmosphere. Here we present measurements from the instrument’s first 250 sols of operation, revealing a spatially and temporally variable meteorology at Jezero. We find that temperature measurements at four heights capture the response of the atmospheric surface layer to multiple phenomena. We observe the transition from a stable night-time thermal inversion to a daytime, highly turbulent convective regime, with large vertical thermal gradients. Measurement of multiple daily optical depths suggests aerosol concentrations are higher in the morning than in the afternoon. Measured wind patterns are driven mainly by local topography, with a small contribution from regional winds. Daily and seasonal variability of relative humidity shows a complex hydrologic cycle. These observations suggest that changes in some local surface properties, such as surface albedo and thermal inertia, play an influential role. On a larger scale, surface pressure measurements show typical signatures of gravity waves and baroclinic eddies in a part of the seasonal cycle previously characterized as low wave activity. These observations, both combined and simultaneous, unveil the diversity of processes driving change on today’s Martian surface at Jezero crater.This work has been funded by the Spanish Ministry of Economy and Competitiveness, through the projects no. ESP2014-54256-C4- 1-R (also -2-R, -3-R and -4-R); Ministry of Science, Innovation and Universities, projects no. ESP2016-79612-C3-1-R (also -2-R and -3-R); Ministry of Science and Innovation/State Agency of Research (10.13039/501100011033), projects no. ESP2016-80320-C2-1-R, RTI2018-098728-B-C31 (also -C32 and -C33), RTI2018-099825-B-C31, PID2019-109467GB-I00 and PRE2020-092562; Instituto Nacional de Técnica Aeroespacial; Ministry of Science and Innovation’s Centre for the Development of Industrial Technology; Spanish State Research Agency (AEI) Project MDM-2017-0737 Unidad de Excelencia “María de Maeztu”—Centro de Astrobiología; Grupos Gobierno Vasco IT1366- 19; and European Research Council Consolidator Grant no 818602. The US co-authors performed their work under sponsorship from NASA’s Mars 2020 project, from the Game Changing Development programme within the Space Technology Mission Directorate and from the Human Exploration and Operations Directorate. Part of this research was carried out at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with the National Aeronautics and Space Administration (80NM0018D0004). G.M. acknowledges JPL funding from USRA Contract Number 1638782. A.G.F. is supported by the European Research Council, Consolidator Grant no. 818602.Peer ReviewedPostprint (published version

Standards of Practice in Acute Ischemic Stroke Intervention: International Recommendations

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