2,717 research outputs found
A contested financial frontier: Banking and empire building in Eritrea, c.1952-73
This article provides an account of the relationship between imperial Ethiopia and Eritrea in the realm of banking governance from the start of the federation to the last years of the imperial regime. It looks in particular at the relationship between the Ethiopian administrations and an Italian bank, Banco di Roma, which had its headquarters in Eritrea from 1948 to 1967 before moving to Addis Ababa. The struggle for control of the economic flows generated by the Italian bank is an index of the changes in centre-periphery linkages between Addis Ababa and the sub-regional centre of Asmara. Archival evidence highlights the multifaced nature of Ethiopian governance and the role performed by the Italian institution in providing alternative sources of diplomatic leverage and wealth accumulation to the Eritrean elite. It is argued that the extraterritorial status enjoyed by Banco di Roma until 1967 was actively tolerated by a section of the Ethiopian establishment, which resorted to an established pattern of imperial governance based on flexibility in return for tribute. This centre-periphery arrangement was harshly opposed by prominent Ethiopian officials from the Ministry of Finance and the National Bank of Ethiopia, who struggled to enforce tighter government control over capital flows within and across the country's borders. The National Bank's final success in the quest for financial centralization drained significant resources out of Eritrea, with adverse effects on the preservation of the pax aethiopica in the former Italian colony
Scaling relations of the colour-detected cluster RzCS 052 at z=1.016 and of some other high redshift clusters
We report on the discovery of the z=1.016 cluster RzCS 052 using a modified
red sequence method, followup spectroscopy and X-ray imaging. This cluster has
a velocity dispersion of 710+-150 km/s, a virial mass of 4.0e14 Msol (based on
21 spectroscopically confirmed members) and an X-ray luminosity of (0.68+-
0.47)e44 ergs/s in the [1-4] keV band. This optically selected cluster appears
to be of richness class 3 and to follow the known L_X-sigma_v relation for high
redshift X-ray selected clusters. Using these data, we find that the halo
occupation number for this cluster is only marginally consistent with what
expected assuming a self-similar evolution of cluster scaling relations,
suggesting perhaps a break of them at z~1. We also rule out a strong galaxy
merging activity between z=1 and today. Finally, we present a Bayesian approach
to measuring cluster velocity dispersions and X-ray luminosities in the
presence of a background: we critically reanalyze recent claims for X-ray
underluminous clusters using these techniques and find that the clusters can be
accommodated within the existing L_X -sigma_v relation.Comment: MNRAS, in pres
Rapid and MR-Independent IK1 activation by aldosterone during ischemia-reperfusion
In ST elevation myocardial infarction (STEMI) context, clinical studies have shown the deleterious
effect of high aldosterone levels on ventricular arrhythmia occurrence and cardiac
mortality. Previous in vitro reports showed that during ischemia-reperfusion, aldosterone
modulates K+ currents involved in the holding of the resting membrane potential (RMP).
The aim of this study was to assess the electrophysiological impact of aldosterone on IK1
current during myocardial ischemia-reperfusion. We used an in vitro model of “border zone”
using right rabbit ventricle and standard microelectrode technique followed by cell-attached
recordings from freshly isolated rabbit ventricular cardiomyocytes. In microelectrode experiments,
aldosterone (10 and 100 nmol/L, n=7 respectively) increased the action potential
duration (APD) dispersion at 90% between ischemic and normoxic zones (from 95±4ms to
116±6 ms and 127±5 ms respectively, P<0.05) and reperfusion-induced sustained premature
ventricular contractions occurrence (from 2/12 to 5/7 preparations, P<0.05). Conversely,
potassium canrenoate 100 nmol/L and RU 28318 1 ÎĽmol/l alone did not affect AP
parameters and premature ventricular contractions occurrence (except Vmax which was
decreased by potassium canrenoate during simulated-ischemia). Furthermore, aldosterone
induced a RMP hyperpolarization, evoking an implication of a K+ current involved in the
holding of the RMP. Cell-attached recordings showed that aldosterone 10 nmol/L quickly
activated (within 6.2±0.4 min) a 30 pS K+-selective current, inward rectifier, with pharmacological
and biophysical properties consistent with the IK1 current (NPo =1.9±0.4 in control vs
NPo=3.0±0.4, n=10, P<0.05). These deleterious effects persisted in presence of RU 28318,
a specific MR antagonist, and were successfully prevented by potassium canrenoate, a non
specific MR antagonist, in both microelectrode and patch-clamp recordings, thus indicating
a MR-independent IK1 activation. In this ischemia-reperfusion context, aldosterone induced
rapid and MR-independent deleterious effects including an arrhythmia substrate (increased
APD90 dispersion) and triggered activities (increased premature ventricular contractions
occurrence on reperfusion) possibly related to direct IK1 activation
A QoE Model for Mulsemedia TV in a Smart Home Environment
The provision to the users of realistic media contents is one of the main goals of future media services. The sense of reality perceived by the user can be enhanced by adding various sensorial effects to the conventional audio-visual content, through the stimulation of the five senses stimulation (sight, hearing, touch, smell and taste), the so-called multi-sensorial media (mulsemedia). To deliver the additional effects within a smart home (SH) environment, custom devices (e.g., air conditioning, lights) providing opportune smart features, are preferred to ad-hoc devices, often deployed in a specific context such as for example in gaming consoles. In the present study, a prototype for a mulsemedia TV application, implemented in a real smart home scenario, allowed the authors to assess the user's Quality of Experience (QoE) through test measurement campaign. The impact of specific sensory effects (i.e., light, airflow, vibration) on the user experience regarding the enhancement of sense of reality, annoyance, and intensity of the effects was investigated through subjective assessment. The need for multi sensorial QoE models is an important challenge for future research in this field, considering the time and cost of subjective quality assessments. Therefore, based on the subjective assessment results, this paper instantiates and validates a parametric QoE model for multi-sensorial TV in a SH scenario which indicates the relationship between the quality of audiovisual contents and user-perceived QoE for sensory effects applications
“Bit Standard”- Bitcoin between reality and risks of a “halfway-money”
This work provides an explanation of the market underlying the evolution due to modern technologies and technical advances, especially in transactions. In this regard, the authors specify the aspect related to the creation of virtual currencies like bitcoin that can circulate thanks to the Blockchain system through miners\u2019 work. The authors consider areas related to the warnings on the use and exchange of virtual currencies. The aim is to conceptualize in a graphical way the current operational transaction in bitcoin through the existing exchange platforms. The authors try to attest the fickleness of the disintermediation ideal founding Bitcoin. The analysis purposed could be interesting and useful to provide a kind of interpretation of the phenomenon and a general overview about Bitcoin system
Searching for galaxy clusters in the Kilo-Degree Survey
In this paper, we present the tools used to search for galaxy clusters in the
Kilo Degree Survey (KiDS), and our first results. The cluster detection is
based on an implementation of the optimal filtering technique that enables us
to identify clusters as over-densities in the distribution of galaxies using
their positions on the sky, magnitudes, and photometric redshifts. The
contamination and completeness of the cluster catalog are derived using mock
catalogs based on the data themselves. The optimal signal to noise threshold
for the cluster detection is obtained by randomizing the galaxy positions and
selecting the value that produces a contamination of less than 20%. Starting
from a subset of clusters detected with high significance at low redshifts, we
shift them to higher redshifts to estimate the completeness as a function of
redshift: the average completeness is ~ 85%. An estimate of the mass of the
clusters is derived using the richness as a proxy. We obtained 1858 candidate
clusters with redshift 0 < z_c < 0.7 and mass 13.5 < log(M500/Msun) < 15 in an
area of 114 sq. degrees (KiDS ESO-DR2). A comparison with publicly available
Sloan Digital Sky Survey (SDSS)-based cluster catalogs shows that we match more
than 50% of the clusters (77% in the case of the redMaPPer catalog). We also
cross-matched our cluster catalog with the Abell clusters, and clusters found
by XMM and in the Planck-SZ survey; however, only a small number of them lie
inside the KiDS area currently available.Comment: 13 pages, 15 figures. Accepted for publication on Astronomy &
Astrophysic
Antiviral effect of bovine lactoferrin saturated with metal ions on early steps of human immunodeficiency virus type 1 infection.
Skin reactions triggered by the use of cosmetic products in nonspecific lipid transfer protein-sensitive patients.
Nonspecific lipid transfer proteins (nsLTPs) are members of the prolamine superfamily and they are found in pollen and food, as well as in latex. Due to the strong stability both against pepsin digestion and thermal denaturation, sensitisation towards these proteins is often associated with severe systemic reactions (angioedema, urticaria, asthma, anaphylaxis, etc.) following the ingestion of both raw or fresh food and cooked or preserved food. Many studies have shown reactivity towards nsLTPs both via inhalation and orally and in this study we present two cases of nsLTPs-sensitive patients who manifested the immediate onset of skin reactions following the use of cosmetic products containing these proteins. Thus, in order to prevent immediate reactions linked to their use, it is necessary to recommend nsLTPs-sensitive patients to avoid the topical use of products containing these proteins (and obviously the ingestion of foods containing these proteins)
Association of patient-reported outcomes and heart rate trends in heart failure. a report from the chiron project
Patient-reported outcomes (PROs) have been previously considered “soft” end-points because of the lack of association of the reported outcome to measurable biological parameters. The present study aimed to assess whether electrocardiographic measures are associated to PROs changes. We evaluated the association between heart rate (HR), QRS and QT/QTc durations and PROs, classified as “good” or “bad” according to the patients’ overall feeling of health, in patients from the Chiron project. Twenty-four chronic heart failure (HF) patients were enrolled in the study (71% male, mean age 62.9 ± 9.4 years, 42% ischemic etiology, 15 NYHA class II and 9 class III) providing 1086 days of usable physiological recordings (4 hours/day). The mean HR was significantly higher in the “bad” than in the “good” PROs class (74.0 ± 6.4 bpm vs 68.0 ± 7.2 bpm; p < 0.001). Conversely, the ratio between movement and rest activities showed significantly higher values in “good” compared to “bad” PROs. We also found significantly longer QTc and QRS durations in patients with “bad” PROs compared to patients with “good” PROs. That in patients with mild to moderate HF, higher HR, wider QRS and longer QTc, as well as a reduced HR ratio between movement and rest, were associated with “bad” PROs is clinically noteworthy because the association of worse PROs with measurable variations of biological parameters may help physicians in evaluating PROs reliability itself and in their clinical decisions. Whether a timely intervention on these biological parameters may prevent adverse outcomes is important and deserves to be investigated in further studies
Left atrial trajectory impairment in hypertrophic cardiomyopathy disclosed by geometric morphometrics and parallel transport
The analysis of full Left Atrium (LA) deformation and whole LA deformational trajectory in time has been poorly investigated and, to the best of our knowledge, seldom discussed in patients with Hypertrophic Cardiomyopathy. Therefore, we considered 22 patients with Hypertrophic Cardiomyopathy (HCM) and 46 healthy subjects, investigated them by three-dimensional Speckle Tracking Echocardiography, and studied the derived landmark clouds via Geometric Morphometrics with Parallel Transport. Trajectory shape and trajectory size were different in Controls versus HCM and their classification powers had high AUC (Area Under the Receiving Operator Characteristic Curve) and accuracy. The two trajectories were much different at the transition between LA conduit and booster pump functions. Full shape and deformation analyses with trajectory analysis enabled a straightforward perception of pathophysiological consequences of HCM condition on LA functioning. It might be worthwhile to apply these techniques to look for novel pathophysiological approaches that may better define atrio-ventricular interaction
- …