Inductive localization accuracy of a passive 3-D coil in an Industry 4.0 environment

In this paper a localization system of a passive 3-D coil is proposed and signal uncertainties due to the 3-D coil's arbitrary orientation are analyzed. The 3-D coil is excited by an alternating primary magnetic field. Geometrically distributed pick-up coils measure the 3-D coil's secondary field. By means of a simulated look-up table that assigns expected voltages from the pick-up coils to the positions of the 3-D coil, the position of the 3-D coil is deduced by a least-squares approach. A basic assumption is that the secondary field is invariant to the orientation of the 3-D coil. This allows a reduction of the computational effort for the look-up table generation and the table search during the localization phase since for each position the field distribution for only one orientation has to be calculated. However, the assumption of invariance to rotation is only valid for a dipole model. In this paper we investigate the localization error introduced by this assumption when using 3-D coils with a geometric extent in an inhomogeneous primary field. Optimized localization methods that decrease the statistical error are proposed. The theoretical results are verified with measurements conducted on a laboratory system.</p

On the dynamics of the adenylate energy system: homeorhesis vs homeostasis.

Biochemical energy is the fundamental element that maintains both the adequate turnover of the biomolecular structures and the functional metabolic viability of unicellular organisms. The levels of ATP, ADP and AMP reflect roughly the energetic status of the cell, and a precise ratio relating them was proposed by Atkinson as the adenylate energy charge (AEC). Under growth-phase conditions, cells maintain the AEC within narrow physiological values, despite extremely large fluctuations in the adenine nucleotides concentration. Intensive experimental studies have shown that these AEC values are preserved in a wide variety of organisms, both eukaryotes and prokaryotes. Here, to understand some of the functional elements involved in the cellular energy status, we present a computational model conformed by some key essential parts of the adenylate energy system. Specifically, we have considered (I) the main synthesis process of ATP from ADP, (II) the main catalyzed phosphotransfer reaction for interconversion of ATP, ADP and AMP, (III) the enzymatic hydrolysis of ATP yielding ADP, and (IV) the enzymatic hydrolysis of ATP providing AMP. This leads to a dynamic metabolic model (with the form of a delayed differential system) in which the enzymatic rate equations and all the physiological kinetic parameters have been explicitly considered and experimentally tested in vitro. Our central hypothesis is that cells are characterized by changing energy dynamics (homeorhesis). The results show that the AEC presents stable transitions between steady states and periodic oscillations and, in agreement with experimental data these oscillations range within the narrow AEC window. Furthermore, the model shows sustained oscillations in the Gibbs free energy and in the total nucleotide pool. The present study provides a step forward towards the understanding of the fundamental principles and quantitative laws governing the adenylate energy system, which is a fundamental element for unveiling the dynamics of cellular life

Photoemission study of SrTiO3 surface layers instability upon metal deposition

In this work we study the Pt/SrTiO3 (STO) interface system using X-ray photoelectron spectroscopy (XPS). The polycrystalline Pt layers with a thickness of about 2-3 nm are deposited by sputtering and thermal evaporation methods on STO(100) single crystals with two different type of terminations. We propose and show local conductivity (LC) measurements as a good method to check whether such very thin metal layers are continuous. The XPS data show that both methods of Pt deposition lead to changes of the chemical composition of the crystal surface layers, and such chemical instability should be taken into consideration when studying the physical properties of a metal-insulator interface

Improved coverage for low-power telemetry systems using telegram splitting

This paper proposes a telegram-splitting transmission concept for low-power telemetry systems. The peak power supply capabilities of energy harvesting generators and small coin cell batteries are often limited, not allowing for the direct operation of state-of-the-art integrated transmitter circuits. Therefore, capacitors are commonly used as energy storing devices for buffering the energy required for the transmission of a whole telegram. Within this paper, we propose to split telegrams into small subpackets without dedicated header information. This way a smaller energy storing capacitor can be used, as the capacitor can be recharged between the transmission of the individual subpackets. The transmission of the subpackets is performed using a pre-defined time schedule, which resigns the need for frame synchronization on each subpacket. It is theoretically shown that this approach can significantly improve the coverage of telemetry systems, without any need for large e nergy storing capacitors. The theoretical results are underlined with actual field test results

Metabolic syndrome is associated with similar long-term prognosis in non-obese and obese patients. An analysis of 45 615 patients from the nationwide LIPIDOGRAM 2004-2015 cohort studies

Aims We aimed to evaluate the association between metabolic syndrome (MetS) and long-term all-cause mortality. Methods The LIPIDOGRAM studies were carried out in the primary care in Poland in 2004, 2006 and 2015. MetS was diagnosed based on the National Cholesterol Education Program, Adult Treatment Panel III (NCEP/ATP III) and Joint Interim Statement (JIS) criteria. The cohort was divided into four groups: non-obese patients without MetS, obese patients without MetS, non-obese patients with MetS and obese patients with MetS. Differences in all-cause mortality was analyzed using Kaplan-Meier and Cox regression analyses. Results 45,615 participants were enrolled (mean age 56.3, standard deviation: 11.8 years; 61.7% female). MetS was diagnosed in 14,202 (31%) by NCEP/ATP III criteria, and 17,216 (37.7%) by JIS criteria. Follow-up was available for 44,620 (97.8%, median duration 15.3 years) patients. MetS was associated with increased mortality risk among the obese (hazard ratio, HR: 1.88 [95% CI, 1.79-1.99] and HR: 1.93 [95% CI 1.82-2.04], according to NCEP/ATP III and JIS criteria, respectively) and non-obese individuals (HR: 2.11 [95% CI 1.85-2.40] and 1.7 [95% CI, 1.56-1.85] according to NCEP/ATP III and JIS criteria respectively). Obese patients without MetS had a higher mortality risk than non-obese patients without MetS (HR: 1.16 [95% CI 1.10-1.23] and HR: 1.22 [95%CI 1.15-1.30], respectively in subgroups with NCEP/ATP III and JIS criteria applied). Conclusions MetS is associated with increased all-cause mortality risk in non-obese and obese patients. In patients without MetS obesity remains significantly associated with mortality. The concept of metabolically healthy obesity should be revised