Riesgo de lesión del ligamento cruzado anterior en fútbol femenino: valoración funcional y mecánicas de aterrizaje

The risk of anterior cross ligament injury is multifactorial and numerous tests have been used to locate possible factors that increase the risk of injury. The objective of the present study was to describe the functional and mechanical deficits of injury risk for the anterior cross ligament (ACL) in semi-professional soccer players, as well as to correlate the risk of injury of women players through a functional test and another of ability. In this case study, 17 women's football players from the First Autonomous and Preferential Autonomous Women of the F.C. Cartagena SAD Females with age range from 14 to 23 years (mean age 17.05 ± 3.24 years) participated. A normal training day was used to perform the following tests: Over Head Squat and Tuck Jump. The outstanding results were that most players showed average risk of functional test injury, on the other hand, no significant associations were shown between Overhead Squat test (OHS) and Tuck Jump tests. Therefore, it is recommended to continue with this line of research in order to detect a possible system of optimal tests to identify the risk of injury of the ACL individually in soccer players. And so, offer coaches the possibility to prescribe individualized work to keep each player away from the LCA injury.El riesgo de lesión del ligamento cruzado anterior es multifactorial y son numerosas las pruebas que han ido utilizando para localizar posibles factores que incrementen el riesgo de lesión. El objetivo del presente estudio fue describir los déficits funcionales y las mecánicas del riesgo lesional para el ligamento cruzado anterior (LCA) en jugadoras de fútbol de categoría semiprofesionales, así como correlacionar el riesgo de lesión de las jugadoras a través de una prueba funcional y otra de habilidad. En este estudio de caso participaron 17 jugadoras de fútbol femenino de categoría Primera Autonómica y Preferente Autonómica Femenina de un club de fútbol con rango de edad de 14 a 23 años (edad media 17,05±3,24 años). Se utilizó un día de entrenamiento normal para realizar las siguientes pruebas: Over Head Squat y Tuck Jump. Los resultados destacados fueron que la mayoría de jugadoras mostraron riesgo medio de lesión en la prueba funcional, por otro lado, no se mostraron asociaciones significativas entre las pruebas de Overhead Squat test (OHS) y Tuck Jump. Por tanto, se recomienda continuar con esta línea de investigación con la finalidad de detectar un posible sistema de pruebas óptimo para identificar el riesgo de lesión del LCA de forma individual en jugadoras de fútbol, y de este modo, ofrecer a los entrenadores la posibilidad de prescribir trabajo individualizado para alejar a cada jugadora de la lesión del LCA

Treatment variability and its relationships to outcomes among patients with Wernicke's encephalopathy: A multicenter retrospective study

Background: Despite guidelines and recommendations, Wernicke's encephalopathy (WE) treatment lacks evidence, leading to clinical practice variability.Aims: Given the overall lack of information on thiamine use for WE treatment, we analyzed data from a large, well-characterized multicenter sample of patients with WE, examining thiamine dosages; factors associated with the use of different doses, frequencies, and routes; and the influence of differences in thiamine treatment on the outcome.Methods: This retrospective study was conducted with data from 443 patients from 21 centers obtained from a nationwide registry of the Spanish Society of Internal Medicine (from 2000 to 2012). Discharge codes and Caine criteria were applied for WE diagnosis, and treatment-related (thiamine dosage, frequency, and route of administration) demographic, clinical, and outcome variables were analyzed.Results: We found marked variability in WE treatment and a low rate of high-dose intravenous thiamine administration. Seventy-eight patients out of 373 (20.9%) received > 300 mg/day of thiamine as initial dose. Patients fulfilling the Caine criteria or presenting with the classic WE triad more frequently received parenteral treatment. Delayed diagnosis (after 24 h hospitalization), the fulfillment of more than two Caine criteria at diagnosis, mental status alterations, and folic acid deficiency were associated significantly with the lack of complete recovery. Malnutrition, reduced consciousness, folic acid deficiency, and the lack of timely thiamine treatment were risk factors for mortality.Conclusions: Our results clearly show extreme variability in thiamine dosages and routes used in the management of WE. Measures should be implemented to ensure adherence to current guidelines and to correct potential nutritional deficits in patients with alcohol use disorders or other risk factors for WE

Geodivulgar: Geología y Sociedad

Con el lema “Geología para todos” el proyecto Geodivulgar: Geología y Sociedad apuesta por la divulgación de la Geología a todo tipo de público, incidiendo en la importancia de realizar simultáneamente una acción de integración social entre estudiantes y profesores de centros universitarios, de enseñanza infantil, primaria, de educación especial y un acercamiento con público con diversidad funcional

Educafarma 10.0

Memoria ID-030. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2021-2022

All-cause mortality in the cohorts of the Spanish AIDS Research Network (RIS) compared with the general population: 1997Ł2010

Abstract Background: Combination antiretroviral therapy (cART) has produced significant changes in mortality of HIVinfected persons. Our objective was to estimate mortality rates, standardized mortality ratios and excess mortality rates of cohorts of the AIDS Research Network (RIS) (CoRIS-MD and CoRIS) compared to the general population. Methods: We analysed data of CoRIS-MD and CoRIS cohorts from 1997 to 2010. We calculated: (i) all-cause mortality rates, (ii) standardized mortality ratio (SMR) and (iii) excess mortality rates for both cohort for 100 personyears (py) of follow-up, comparing all-cause mortality with that of the general population of similar age and gender. Results: Between 1997 and 2010, 8,214 HIV positive subjects were included, 2,453 (29.9%) in CoRIS-MD and 5,761 (70.1%) in CoRIS and 294 deaths were registered. All-cause mortality rate was 1.02 (95% CI 0.91-1.15) per 100 py, SMR was 6.8 (95% CI 5.9-7.9) and excess mortality rate was 0.8 (95% CI 0.7-0.9) per 100 py. Mortality was higher in patients with AIDS, hepatitis C virus (HCV) co-infection, and those from CoRIS-MD cohort (1997. Conclusion: Mortality among HIV-positive persons remains higher than that of the general population of similar age and sex, with significant differences depending on the history of AIDS or HCV coinfection

Influencia de la composición corporal en la condición física de futbolistas de 10-11 años

Objectives: The objective of the present study was to analyze the body composition and physical fitness of 10- to 11-year-old football players, analyzing the differences in physical fitness according to Body Mass Index (BMI) and percentage of fat mass (% FM), as well as the correlations between body composition and physical fitness. Methods: Twenty-eight male 10- to 11-year-old football players participated in the study, with an age range of 10 to 11 years (average age 10.39 years ± 0.49). The players performed the tests in abnormal training day. The variables assessed were: Body composition (Tanita BC 418-MA), blood pressure and heart rate (Visomat Comfort 20/40 arm blood pressure monitor), jump test (Abalakov jump on Optojump platform) and aerobic capacity test (Course Navette Test 20m, CN). The software used to perform the statistical analysis was SPSS Statistics 23.0. Findings: The analyses showed significant differences in maximal oxygen consumption (VO?max), BMI and % FM when comparing by age. With regard to BMI, significant differences were found in diastolic and systolic blodd pressure at rest (DBP and SBP), and, according to % FM, in rest DBP. The significant correlations between physical fitness and body composition according to BMI were negative in the variables of CN stage, CN distance, CN FSR (final speed reached), VO?max, and was positive in SBP and DBP. According to % FM, the significant correlations were negative in CN stage, CN distance, CN FSR, VO?max., and Abalakov jump (ABKJ), and they were positive in SBP and DBP. Conclusions: It is recommended to carry out intervention programs with the aim of improving the body composition of football players at school age, because this will have positive effects on their aerobic capacity, jumping and blood pressure

Valoración del riesgo de lesión del ligamento cruzado anterior en jugadoras de fútbol amateur

Few studies have assessed ACL injury risk in women's football using a multifactorial approach. The aim of the present study was to describe the functional deficits and asymmetries manifested by female football players in different tests, in order to perform an integrative analysis of injury risk from different functional and mechanical perspectives. This case study involved 17 female football players from the Spanish Leagues of “Primera Autonómica” and “Preferente Autonómica Femenina”, aged from 14 to 23 years old. The tests applied were: OverHead Squat (OHS), Drop Vertical Jump Test (DVJ), Tuck Jump (TJ) and Triple Hop Test (TH). It was found that all players presented better results for the dominant leg, showing a higher mean lateral trunk flexion (TLFA) when landing with the left leg (8.88±5.15º) than when landing with the right leg (7.05±5.40º) in the unipodal DVJ. Furthermore, it was found that a large proportion of the players (41.20%) presented a medium risk of injury in the OHS, as well as a mean medial knee displacement (valgus) in the bipodal DVJ landing (-1.88 cm), while most of them (65%) did not show neuromuscular asymmetries of the lower limb. In conclusion, the players mainly show functional deficits in core stability (CORE) and knee stability to resist and transmit forces in high-risk actions for the ACL such as jump-landing tasks. Therefore, these deficits should be addressed comprehensively with female players.Escasos trabajos han valorado el riesgo de lesión del LCA en fútbol femenino mediante un enfoque multifactorial. El objetivo del presente estudio fue describir los déficits funcionales y las asimetrías manifestadas por jugadoras de fútbol en diferentes pruebas de valoración, con el fin de realizar un análisis integrador del riesgo de lesión desde diferentes perspectivas funcionales y mecánicas. En este estudio de caso participaron 17 jugadoras de fútbol femenino de categoría Primera Autonómica y Preferente Autonómica Femenina española, con rangos de edad de 14 a 23 años. Las pruebas realizadas fueron: OverHead Squat (OHS), Drop Vertical Jump Test (DVJ), Tuck Jump (TJ) y Triple Hop Test (TH). Se halló que todas las jugadoras presentaron mejores resultados para la pierna dominante, mostrando una media mayor de flexión lateral del tronco (TLFA) al aterrizar con la pierna izquierda (8,88±5,15 º) que al aterrizar con la derecha (7,05±5,40 º) en el DVJ unipodal. Además, se encontró que gran parte de las jugadoras (41,20%) presentaron riesgo medio de lesión en el OHS, así como un desplazamiento medio de las rodillas en sentido medial (valgo) en el aterrizaje bipodal del DVJ (-1,88 cm), mientras que la mayoría de ellas (65%) no mostraron asimetrías neuromusculares de miembro inferior. En conclusión, las jugadoras muestran principalmente déficits funcionales en la estabilidad central (CORE) y en la estabilidad de rodilla para resistir y transmitir fuerzas en acciones de alto riesgo para el LCA como los saltos-aterrizajes. Por tanto, estos déficits deberían ser abordados de forma integral con las futbolistas

Neurological comorbidity is a predictor of death in Covid-19 disease: A cohort study on 576 patients

[Introduction]: Prognosis of Coronavirus disease 2019 (Covid-19) patients with vascular risk factors, and certain comorbidities is worse. The impact of chronic neurological disorders (CND) on prognosis is unclear. We evaluated if the presence of CND in Covid-19 patients is a predictor of a higher in-hospital mortality. As secondary endpoints, we analyzed the association between CND, Covid-19 severity, and laboratory abnormalities during admission.[Methods]: Retrospective cohort study that included all the consecutive hospitalized patients with confirmed Covid-19 disease from March 8th to April 11th, 2020. The study setting was Hospital Clínico, tertiary academic hospital from Valladolid. CND was defined as those neurological conditions causing permanent disability. We assessed demography, clinical variables, Covid-19 severity, laboratory parameters and outcome. The primary endpoint was in-hospital all-cause mortality, evaluated by multivariate cox-regression log rank test. We analyzed the association between CND, covid-19 severity and laboratory abnormalities.[Results]: We included 576 patients, 43.3% female, aged 67.2 years in mean. CND were present in 105 (18.3%) patients. Patients with CND were older, more disabled, had more vascular risk factors and comorbidities and fewer clinical symptoms of Covid-19. They presented 1.43 days earlier to the emergency department. Need of ventilation support was similar. Presence of CND was an independent predictor of death (HR 2.129, 95% CI: 1.382–3.280) but not a severer Covid-19 disease (OR: 1.75, 95% CI: 0.970–3.158). Frequency of laboratory abnormalities was similar, except for procalcitonin and INR.[Conclusions]: The presence of CND is an independent predictor of mortality in hospitalized Covid-19 patients. That was not explained neither by a worse immune response to Covid-19 nor by differences in the level of care received by patients with CND.Peer reviewe

Treatment variability and its relationships to outcomes among patients with Wernicke's encephalopathy : A multicenter retrospective study

CatedresBackground: Despite guidelines and recommendations, Wernicke's encephalopathy (WE) treatment lacks evidence, leading to clinical practice variability. Aims: Given the overall lack of information on thiamine use for WE treatment, we analyzed data from a large, well-characterized multicenter sample of patients with WE, examining thiamine dosages; factors associated with the use of different doses, frequencies, and routes; and the influence of differences in thiamine treatment on the outcome. Methods: This retrospective study was conducted with data from 443 patients from 21 centers obtained from a nationwide registry of the Spanish Society of Internal Medicine (from 2000 to 2012). Discharge codes and Caine criteria were applied for WE diagnosis, and treatment-related (thiamine dosage, frequency, and route of administration) demographic, clinical, and outcome variables were analyzed. Results: We found marked variability in WE treatment and a low rate of high-dose intravenous thiamine administration. Seventy-eight patients out of 373 (20.9%) received > 300 mg/day of thiamine as initial dose. Patients fulfilling the Caine criteria or presenting with the classic WE triad more frequently received parenteral treatment. Delayed diagnosis (after 24 h hospitalization), the fulfillment of more than two Caine criteria at diagnosis, mental status alterations, and folic acid deficiency were associated significantly with the lack of complete recovery. Malnutrition, reduced consciousness, folic acid deficiency, and the lack of timely thiamine treatment were risk factors for mortality. Conclusions: Our results clearly show extreme variability in thiamine dosages and routes used in the management of WE. Measures should be implemented to ensure adherence to current guidelines and to correct potential nutritional deficits in patients with alcohol use disorders or other risk factors for WE

Alcoholic Liver Disease Among Patients with Wernicke Encephalopathy: A Multicenter Observational Study

Background: data regarding the association between Wernicke encephalopathy (WE) and alcoholic liver disease (ALD) are scarce in spite of alcohol consumption being the main risk factor for WE. Aims: to describe the frequency of ALD in a cohort of patients diagnosed with WE and alcohol use disorders (AUDs) and to compare the characteristics of WE patients with and without ALD. Methods: we conducted an observational study in 21 centers through a nationwide registry of the Spanish Society of Internal Medicine. WE Caine criteria were applied and demographic, clinical, and outcome variables were analyzed. Results: 434 patients were included in the study, of which 372 were men (85.7%), and the mean age was 55 ± 11.8 years. ALD was present in 162 (37.3%) patients and we found a higher percentage of cases with tremor, flapping and hallucinations in the ALD group. A total of 22 patients (5.0%) died during admission (7.4% with ALD vs 3.7% without ALD; P = 0.087). Among the ALD patients, a relationship between mortality and the presence of anemia (Odds ratio [OR]=4.6 Confidence interval [CI]95% 1.1-18.8; P = 0.034), low level of consciousness (OR=4.9 CI95% 1.1-21.2; P = 0.031) and previous diagnosis of cancer (OR=10.3 CI95% 1.8-59.5; P = 0.009) was detected. Complete recovery was achieved by 27 patients with ALD (17.8%) and 71 (27.8%) without ALD (P = 0.030). Conclusion: the association of WE and ALD in patients with AUDs is frequent and potentially linked to differences in clinical presentation and to poorer prognosis, as compared to alcoholic patients with WE without ALD