The reaction to working class unrest, 1911-1914.

The period 1911-14 has, until late, been largely ignored by historians, and, like so many other periods, even when it has been covered, there has been little attempt to investigate the attitudes of the people of the time to the events. This thesis endeavours to compensate for this, at least to a small degree. It examines the class structure of the period, and then looks at the working class unrest of the time from the eyes of the community. It was an especially strike-prone age and for the first time, there were national stoppages and sympathetic walk-outs, with the threat of Syndicalism lurking in the background. Some believed that revolution was imminent. Unfortunately, the sources have been limited by the availability of material, but, nevertheless, the thesis represents the nearest approximation possible to public opinion. It reveals that the nation did not have a single view on any of the major disputes, and that the split was not entirely along •political lines. Some Tories were quite sympathetic to the working class, whilst certain Liberals were extremely traditional and authoritarian. Moreover, attitudes did not remain constant, but changed with events. Finally, the results of this study are looked at in relation to several theories on public opinion, and, as such, virtually represent a case study for sociological theorists

Galaxy clustering in 3D and modified gravity theories

We study Modified Gravity (MG) theories by modelling the redshifted matter power spectrum in a spherical Fourier-Bessel (sFB) basis. We use a fully non-linear description of the real-space matter power-spectrum and include the lowest-order redshift-space correction (Kaiser effect), taking into account some additional non-linear contributions. Ignoring relativistic corrections, which are not expected to play an important role for a shallow survey, we analyse two different modified gravity scenarios, namely the generalised Dilaton scalar-tensor theories and the f(R) models in the large curvature regime. We compute the 3D power spectrum C s ℓ (k 1 ,k 2 ) for various such MG theories with and without redshift space distortions, assuming precise knowledge of background cosmological parameters. Using an all-sky spectroscopic survey with Gaussian selection function φ(r)∝exp(−r 2 /r 2 0 ) , r 0 =150h −1 Mpc , and number density of galaxies N ¯ =10 −4 Mpc −3 , we use a χ 2 analysis, and find that the lower-order (ℓ≤25) multipoles of C s ℓ (k,k ′ ) (with radial modes restricted to k25 modes can further reduce the error bars and thus in principle make cosmological gravity constraints competitive with solar system tests. However this will require an accurate modelling of non-linear redshift space distortions. Using a tomographic β(a) -m(a) parameterization we also derive constraints on specific parameters describing the Dilaton models of modified gravity

Disruption and bactericidal indices depicted in polygonal graphs to show multiple outcome effects of root canal irrigant supplements on single and dual species biofilms

Objectives: The aims of this study were to (1) investigate the relative time-dependent disruption and bactericidal effects of detergent-type surfactants on single- or dual-species biofilms of root canal isolates and (2) to examine the utility of polygonal graphs for depiction of biofilm disruption and cell killing. Materials and methods: Single-species biofilms of Streptococcus sanguinis, Enterococcus faecalis, Fusobacterium nucleatum and Porphyromonas gingivalis were grown on nitro-cellulose membranes for 72 h and immersed in Tween®80, cetyltrimethylammoniumbromide (CTAB), and sodium dodecyl sulphate (SDS) for 1-, 5- or 10-min (n = 3 per test). The number of viable and non-viable bacteria “disrupted” from the biofilm and those “remaining-attached” was determined using a viability stain in conjunction with fluorescence microscopy. The data were analysed using non-parametric Kruskal-Wallis test with 5% significance level. Results: Gram-negative obligate anaerobes were more susceptible to cell removal than gram-positive facultative anaerobes. The majority of cells were disrupted after 1-min of exposure; however, the extent varied according to the agent and species. CTAB and SDS were more effective than Tween 80™ at disrupting biofilms and killing cells but all agents failed to achieve 100% disruption/kill. Conclusions: Biofilm disruption and cell viability were influenced by the species, the test agent and the duration of exposure. CTAB and SDS were more effective in biofilm disruption than Tween 80™. Graphical depiction of biofilm disruption- and viability-outcomes provides an alternative means of simultaneously visualising and analysing relative efficacy in different domains. Clinical relevance: Surfactants were not as effective at biofilm disruption as NaOCl but may be added to other non-disruptive antibacterial agents to enhance this property

Effect of silver content on the structure and antibacterial activity of silver-doped phosphate-based glasses

Staphylococcus aureus can cause a range of diseases, such as osteomyelitis, as well as colonize implanted medical devices. In most instances the organism forms biofilms that not only are resistant to the body's defense mechanisms but also display decreased susceptibilities to antibiotics. In the present study, we have examined the effect of increasing silver contents in phosphate-based glasses to prevent the formation of S. aureus biofilms. Silver was found to be an effective bactericidal agent against S. aureus biofilms, and the rate of silver ion release (0.42 to 1.22 µg·mm–2·h–1) from phosphate-based glass was found to account for the variation in its bactericidal effect. Analysis of biofilms by confocal microscopy indicated that they consisted of an upper layer of viable bacteria together with a layer (20 µm) of nonviable cells on the glass surface. Our results showed that regardless of the silver contents in these glasses (10, 15, or 20 mol%) the silver exists in its +1 oxidation state, which is known to be a highly effective bactericidal agent compared to that of silver in other oxidation states (+2 or +3). Analysis of the glasses by 31P nuclear magnetic resonance imaging and high-energy X-ray diffraction showed that it is the structural rearrangement of the phosphate network that is responsible for the variation in silver ion release and the associated bactericidal effectiveness. Thus, an understanding of the glass structure is important in interpreting the in vitro data and also has important clinical implications for the potential use of the phosphate-based glasses in orthopedic applications to deliver silver ions to combat S. aureus biofilm infections

Demand management and stock control in the licensed trade; is it so simple?

There are about 60,000 public houses in the UK and more than half of these operate as small businesses. By 1990 businesses with less than 200 employees accounted for nearly a third of total UK employment [6] with the consequential effect that supply of goods from supplier through producer to customer using small businesses has become more significant over time. While the large brewers operate their houses by employing well trained managers and other staff, most of the proprietors of the small businesses have little or no formal training themselves, and have minimal knowledge of effective stock control. Moreover, they are unaware of any need for such knowledge. This article uses the comparative case study approach to illustrate demand management and stock control in a leased public house run as a small business, and a brewery managed public house

Development of an in vitro periodontal biofilm model for assessing antimicrobial and host modulatory effects of bioactive molecules

Background: Inflammation within the oral cavity occurs due to dysregulation between microbial biofilms and the host response. Understanding how different oral hygiene products influence inflammatory properties is important for the development of new products. Therefore, creation of a robust host-pathogen biofilm platform capable of evaluating novel oral healthcare compounds is an attractive option. We therefore devised a multi-species biofilm co-culture model to evaluate the naturally derived polyphenol resveratrol (RSV) and gold standard chlorhexidine (CHX) with respect to anti-biofilm and anti-inflammatory properties.<p></p> Methods: An in vitro multi-species biofilm containing <i>S. mitis, F. nucleatum, P. Gingivalis</i> and <i>A. Actinomycetemcomitans</i> was created to represent a disease-associated biofilm and the oral epithelial cell in OKF6-TERT2. Cytotoxicity studies were performed using RSV and CHX. Multi-species biofilms were either treated with either molecule, or alternatively epithelial cells were treated with these prior to biofilm co-culture. Biofilm composition was evaluated and inflammatory responses quantified at a transcriptional and protein level.<p></p> Results: CHX was toxic to epithelial cells and multi-species biofilms at concentrations ranging from 0.01-0.2%. RSV did not effect multi-species biofilm composition, but was toxic to epithelial cells at concentrations greater than 0.01%. In co-culture, CHX-treated biofilms resulted in down regulation of the inflammatory chemokine IL-8 at both mRNA and protein level. RSV-treated epithelial cells in co-culture were down-regulated in the release of IL-8 protein, but not mRNA.<p></p> Conclusions: CHX possesses potent bactericidal properties, which may impact downstream inflammatory mediators. RSV does not appear to have bactericidal properties against multi-species biofilms, however it did appear to supress epithelial cells from releasing inflammatory mediators. This study demonstrates the potential to understand the mechanisms by which different oral hygiene products may influence gingival inflammation, thereby validating the use of a biofilm co-culture model.<p></p&gt

The social role of accounting: views and perceptions of the accounting community in Libya towards corporate social responsibility and accountability

The paper explores views and perceptions amongst members of the accounting community in Libya regarding the perceived basic features of the current corporate reporting and disclosure practices of the Libyan Business Organisations (LBOs). Extending these practices to embrace reporting and disclosure of social and environmental related information (CSR), and the extent to which notions of corporate social responsibility and accountability are acceptable in Libya are examined. Five groups of users of published accounts in Libya participated in the study, including academic accountants, financial managers (or accountants), government officials, bank credit officers and external auditors. A questionnaire survey of the 438 participants, drawing on the Al-khater and Naser (2003) study, was employed as the main data collection method. The findings demonstrate that currently most LBOs communicate limited information to a limited set of stakeholders. The disclosure of more social and environmental information was widely accepted and viewed as potentially leading to some beneficial socio-economic effects at the macro level. There was general agreement that the LBOs’ annual reports should reflect the interaction between their operations and the society in which they operate, recognizing the right of different stakeholders to information about the actions for which LBOs could be held responsible. The Law was viewed as the key source of establishing such responsibilities rather than professional guidelines

Film support and the challenge of ‘sustainability’: on wing design, wax and feathers, and bolts from the blue

In recognition of the importance of film in generating both economic and cultural value, the UK Labour government set up a new agency – the United Kingdom Film Council (UKFC) – in 2000 with a remit to build a sustainable film industry. But, reflecting a plethora of differing expectations in relation to the purposes behind public support for film, the UKFC's agenda shifted and broadened over the organisation's lifetime (2000–11). Apparently unconvinced by the UKFC's achievements, the Coalition government which came to power in May 2010 announced the Council's abolition and reassigned its responsibilities as part of a general cost-cutting strategy. Based on original empirical research, this article examines how the UKFC's sense of strategic direction was determined, how and why the balance of objectives it pursued changed over time and what these shifts tell us about the nature of film policy and the challenges facing bodies that are charged with enacting it in the twenty-first century