A prospective study of risk factors and feto-maternal outcome of preterm labor in OG department of tertiary care centre of South Gujarat

Background: Every year globally, an estimated 15 million babies are born preterm and this number is rising over major parts of the world. Severe morbidity is common in neonates born before 32-34 weeks of gestation. Management of prematurity is a team approach by the obstetrician and the pediatrician. Methods: This prospective observational study was conducted in the Department of Obstetrics and Gynecology, NCH, Surat from October 2019 to October 2020. 120 consenting consecutive subjects fulfilling inclusion criteria were enrolled. Results: The most common risk factor for preterm labor in my study was PPROM (premature rupture of membranes). 27% subjects were diagnosed with threatened preterm labor. 22% subjects delivered preterm due to advanced labor. Labor arrest with tocolytic drug nifedipine was attempted in 30 subjects without any complications, which was successful in 19 subjects. The most common maternal complication in preterm labor was postpartum hemorrhage. All neonates were admitted to NICU, amongst them 45 developed complications. The most common complication in preterm neonates was respiratory distress. The rate of early neonatal death was 6.6%. Conclusions: Inspite of advances in antenatal care and neonatal services, preterm birth remains a burden to families. Strengthening of referral systems to make sure that high risk patients are managed at tertiary care centers with NICU facilities will improve the neonatal outcome

Accessibility of promoter DNA is not the primary determinant of chromatin-mediated gene regulation

DNA accessibility is thought to be of major importance in regulating gene expression. We test this hypothesis using a restriction enzyme as a probe of chromatin structure and as a proxy for transcription factors. We measured the digestion rate and the fraction of accessible DNA at almost all genomic AluI sites in budding yeast and mouse liver nuclei. Hepatocyte DNA is more accessible than yeast DNA, consistent with longer linkers between nucleosomes, and suggesting that nucleosome spacing is a major determinant of accessibility. DNA accessibility varies from cell to cell, such that essentially no sites are accessible or inaccessible in every cell. AluI sites in inactive mouse promoters are accessible in some cells, implying that transcription factors could bind without activating the gene. Euchromatin and heterochromatin have very similar accessibilities, suggesting that transcription factors can penetrate heterochromatin. Thus, DNA accessibility is not likely to be the primary determinant of gene regulation.Fil: Chereji, Razvan V.. National Institutes of Health; Estados UnidosFil: Eriksson, Peter R.. National Institutes of Health; Estados UnidosFil: Ocampo, Josefina. National Institutes of Health; Estados Unidos. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; ArgentinaFil: Prajapati, Hemant Kumar. National Institutes of Health; Estados UnidosFil: Clark, David. National Institutes of Health; Estados Unido

Primary ovarian leiomyoma: a diagnostic dilemma

Among all benign primary ovarian smooth muscle tumors, ovarian leiomyoma is uncommon accounting for .5-1% of all tumors. most of these are unilateral small in size and generally occur in premenopausal women. this paper presents a case report of primary ovarian leiomyoma i.e. 29 years old women with complaints of abdominal pain. the right ovarian mass was histologically diagnosed as ovarian leiomyoma. unlike other smooth muscle tumors of uterine origin, there are no definite histological criteria to categorize smooth muscle tumor of ovary

Experimental Investigation of Single Cylinder Diesel Engine using Tyre Pyrolysis Oil (TPO) Blends

Increasing industrialization and motorization led to a significant rise in demand of petroleum products. As these are the non-renewable resources, it will be troublesome to predict the availability of these resources in the future, resulting in uncertainty in its supply and price and is impacting growing economies like India importing 80% of the total demand of the petroleum products. Many attempts have been made by different researchers to find out alternate fuels for Internal Combustion engines. Many alternate fuels like Biodiesel, LPG (Liquefied Petroleum Gas), CNG (Compressed Natural Gas) and Alcohol are being used nowadays by different vehicles. In this context pyrolysis of scrap tires can be used effectively to produce oil, thereby solving the problem of waste tire disposal. In the present study, Experimental investigations were carried out to evaluate the performance and emission characteristics of a single cylinder diesel engine fueled by TPO10, TPO15, and TPO20 at a crank angle 260 before TDC (Top Dead Centre) and injection pressure of 190 bar keeping the blend quality by controlling the density and viscosity of tire pyrolysis oil within permissible limit of euro IV diesel requirement. The performance and emission results were analyzed and compared with that of diesel fuel operation. The results of investigations indicate that the brake thermal efficiency of the TPO - DF blend decreases by 2 to 3%. CO emissions are well within permissible limits. HC emissions are higher by about 20 to 40% at partial load whereas smoke opacity is lower by about 20 to 30% as compared to diesel fuel

A Review of Internal Combustion Engine Design

The most successful inventions of human includes internal combustion engine (I C Engine) as top of the list. The recent emphasis on fuel economy, pollution control and other automobile fields like low friction body profile has also stimulated theoretical searches for an automobile. Studies have found no alternative type that promises to have significant advantages in fuel economy or pollution control than conventional I C Engines. But from these studies, it appears that the conventional types of spark-ignition and Diesel engines will remain in their present predominant position in land and sea transportation and for industrial and portable power for the foreseeable future. And so, here is an approach to have combined design aspects for all basic I C Engine components in one paper. Design aspects includes components like, piston, piston rings, cylinder, cylinder head, connecting rod, crank and crank shaft, cam and cam shaft along with valve and valve gear mechanism. A paper can be the base for future detailed designing work of I C Engine along with stress analysis and simulation

A Review of Palm Oil Biodiesel under Long-Term Storage Conditions

Palm-oil biodiesel is widely used as alternative to diesel; the influences of long-term oxidative degradation on its burning characteristics are a matter of some concern. To further our understanding of this issue, this study investigated the heat release, carbon residue, flash point, and cetane index, oxidative stability, Density, Viscosity, Total acid no. of palm-oil biodiesel in a constant-temperature water bath after long-term storage. DOI: 10.17762/ijritcc2321-8169.15016

Suppression of four-wave mixing in hot rubidium vapor using ladder scheme Raman absorption

We experimentally investigate the effectiveness of four-wave mixing suppression in a double-interaction scheme by introducing an additional ladder-type two-photon Raman absorption resonance for one of the optical fields. We propose several possible interaction configurations involving either one or two isotopes of Rb and experimentally demonstrate the possibility of efficient four-wave mixing suppression in both electromagnetically induced transparency and far-detuned Raman cases. (C) 2017 Optical Society of Americ

Design of Lean to Roof Steel Trusses with Hollow Circular tube using IS 875 (part-III):2015 & IS 800:2007

At present, SP-38:1987 is available which provides design for lean to roof type trusses and pitch roof trusses. The design of lean to roof truss has been carried out as per IS 800:1984 IS 875 (Part-III):1964. Afterwards IS 800:1984 is revised in 2007, which is based on limit state method. Also, IS 875 (Part-III) is updated in 1987 and then in 2015 considering climate changes and economical parameters. Accordingly, study has been done to revise the design of trusses given in SP-38:1987. In the present study, design and comparison of lean to roof type truss with steel circular hollow tube section have been carried out using IS 875 (Part-III):2015 and IS 800:2007 limit state method using STAAD Pro. and their results compared with SP-38:1987 results. This study includes lean to roof truss system considering different parameters like span, spacing of truss, slope of roof and wind zones with all cases of wind load. At the end, a compiled report will be prepared, which will be helpful to design engineers to provide economic, easier, faster approach for designing of steel trusses

Aggressive angiomyxoma of the vulva: an uncommon entity

AA is a rare locally invasive mesenchymal tumor predominantly presenting in women of reproductive age group, having a moderate to high risk for local relapse. Hence, it needs to be differentiated from another mesenchymal tumor occuring in this region. We present a case of a 50 year old female with a large, polypoidal, spongy mass on the right labia majora

Langerhans’ cell histiocytosis (histiocytosis X): A rare and diverse group of disorder in children

Langerhans cell histiocytosis is a rare disorder of unknown etiology with proliferation of Langerhans’ cells which mayinfiltrate a single or multiple organs. We report a case of 5-year-old child presented with skin lesions since the age of4 months and fever for 10 days where skin biopsy revealed histiocytosis