Ayurvedic management of Chronic Kidney Disease : A Case Report

Background: Chronic kidney disease is a spectrum of different pathophysiologic processes associated with abnormal kidney function and a progressive decline in glomerular filtration rate. Globally it is the 12th cause of death and 17th cause of disability. Clinically this condition can be correlated to madumeha and mutrakshaya. Methodology: A 60yr old female patient with uncontrolled type 2 diabetes mellitus and chronic kidney disease (stage 4) was advised hemo-dialysis, which she was not willing to undergo, attended out patient department of Kayachikitsa, at SDM College of Ayurveda & Hospital, Hassan. Patient was treated with shamanaaushadi, Mustadiyapana basti, and with specific pathyaahara. Assessment was done before and after treatment with serum creatinine, eGFR and oedema grade. Result: After 9 days of treatment, there was significant change in the bilateral pedal oedema, urine output, general condition and also reduction in the serum creatinine. Conclusion: Chronic kidney disease was effectively managed by treatment modalities mentioned in Ayurveda after proper assessment of the dosha, dushya and vyadhi avasta

Modifications in biphasic liquid-scintillation vial system for radiometry

Several modifications of the biphasic liquid-scintillation vial system for radiometry have been tried in order to improve the counting efficiency. The biphasic system consisted of an inner sterile vial containing medium and substrate, and an outer liquid-scintillation vial lined on the inside with filter paper impregnated with scintillation fluors and alkali. The system gave an overall counting efficiency of 14.6%. Substitution of methanolic NaOH for impregnation of the paper raised the counting efficiency to 29.1%. This could be further enhanced to 33.8% by lining only half of the outer vial with filter paper, thereby allowing improved optical transmission of scintillation light. Increasing the amount of fluor did not change the efficiency significantly. A complete interchange in the system, whereby half of the inner vial was lined with filter paper and was otherwise empty, while the outer vial contained the medium and substrate, gave the highest efficiency (36.9%). This also allowed the use of larger amounts of medium and the inoculum

Photoelectrochemical properties of mesoporous NiOx deposited on technical FTO via nanopowder sintering in conventional and plasma atmospheres

Nanoporous nickel oxide (NiO x ) has been deposited with two different procedures of sintering (CS and RDS). Both samples display solid state oxidation at about 3.1 V vs Li+/Li. Upon sensitization of CS/RDS NiO x with erythrosine b (ERY), nickel oxide oxidation occurs at the same potential. Impedance spectroscopy revealed a higher charge transfer resistance for ERY-sensitized RDS NiO x with respect to sensitized CS NiO x . This was due to the chemisorption of a larger amount of ERY on RDS with respect to CS NiO x . Upon illumination the photoinduced charge transfer between ERY layer and NiO x could be observed only with oxidized CS. Photoelectrochemical effects of sensitized RDS NiO x were evidenced upon oxide reduction. With the addition of iodine RDS NiOx electrodes could give the reduction iodine → iodide in addition to the reduction of RDS NiO x . p-type dye sensitized solar cells were assembled with RDS NiO x photocathodes sensitized either by ERY or Fast Green. Resulting overall efficiencies ranged between 0.02 and 0.04 % upon irradiation with solar spectrum simulator (Iin : 0.1 W cm −2 )

Epidemiological Profile of Cleft Lip and Palate Patients Attending Tertiary Care Hospital and Medical Research Centre, Belgaum, Karnataka-A Hospital Based Study

Abstract: Cleft Lip and/or Palate (CL±P) is the most common congenital malformation of the face and it

Multi-objective optimization of machining parameter in laser drilling of glass microballoon/epoxy syntactic foams

The effect of CO2 laser drilling on glass microballoon/epoxy syntactic foams are investigated in this study to optimize machining parameters to achieve a clean hole for various industrial applications. The epoxy matrix is reinforced with glass microballoons in concentrations of 0, 20 and 40 vol%. Cutting speed, laser power and additive percentage are input parameters for optimization. Kerf taper angle, surface roughness and ovality percentage are used as output responses to evaluate hole quality. For the optimization study, hybrid multi-criteria decision-making methods such as grey relational analysis and multi-objective optimization with ratio assessment methods are used, with equal weightage given to each output response. According to the study, low power and high speed produce better machining results such as a smaller kerf taper angle, lower surface roughness and a lower ovality percentage. Furthermore, a higher additive percentage is not appropriate for laser in epoxy/glass microballoon composite because it burns the area near the laser and increases surface roughness. © 2023 The Author(s

A geological map of the southern Deccan Traps, India and its structural implications

A geological map of an area of over 125,000 km2 within the southern Deccan Traps, India is presented, which is based upon variations in the basalt geochemistry. It represents a synthesis of new data and earlier work. The use of large data sets has allowed stratigraphic boundaries to be established with greater accuracy over a much larger area than before. The geochemical sections demonstrate that the southward overstepping stratigraphic style encountered along the Ghats ridge has an essentially north to south polarity and that there appears to be detectable overstep in an east to west sense. However, the stratigraphy defines a pronounced coastward-dipping monoclinal flexure across the Western Ghats ridge between 16°N and 18°N. The data are consistent with two models of eruption. The first considers the Deccan eruptive focus to have been fixed throughout the volcanic episode, producing an essentially annular flow pattern. The second considers the flow pattern to have been generated from a southerly migrating eruptive centre, resulting from the northerly drift of India over a fixed hotspot. Both hypotheses are consistent with recent quantitative models which suggest that rapid and voluminous flood basalt eruptions are the result of continental rifting events associated with plume-generated thermal 'highs'. Until a causal link between established plume/hotspot trails and impact sites can be satisfactorily demonstrated, we find it unnecessary to invoke a cataclysmic impact event as an explanation for the Deccan eruptions

A randomized controlled trial comparing the efficacy of intralesional 5-fluorouracil versus triamcinolone acetonide in the treatment of keloids

Background: Effective keloid management is still a distant dream in spite of many recent modalities being tried for the same. Although many treatment protocols have shown efficacy of varying degrees, there are few systematic randomized trials comparing them. Objective: To compare the efficacy of intralesional 5-Fluorouracil versus Triamcinolone acetonide in the treatment of Keloids. Materials and Methods: This randomized controlled trial was conducted on 30 patients with keloids, randomly divided into two groups of 15 each, treated with intralesional 5-fluorouracil (Group A) or triamcinolone acetonide (Group B). The groups were compared for reduction in the size of keloid, pain relief, and the incidence of adverse effects. Statistical analysis was done using the unpaired student t- test and test of proportion. Results: The reduction in the size of the keloid was found to be significantly better in Group B (71.23%) than in Group A (57.48%) with a P value of 0.04. The difference in the reduction of pain, as assessed by the visual analog scale, between Groups A (18%) and B (24%), was found to be insignificant (P value - 0.47). Although the incidence of complications in Group A was three times higher than those in Group B, the difference was not statistically significant (P value - 0.13). Conclusion: Reduction in the size of the keloid, which was the main aim of this study was significantly better in those treated with triamcinolone acetonide than those treated with 5-fluorouracil. The other parameters like reduction of pain and the incidence of adverse effects were comparable in both the groups

A cross sectional study to develop a scale on health related QOL for assessing the effect of Unhealthy Food Habits in apparently Healthy Subjects

Background: Non communicable diseases continue to be an important public health problem and are responsible for the major proportion of mortality and morbidity in India and about 60% of deaths in India are due to these diseases. This is due to drastic change in the life style and food habits which are affecting the quality of life of the person. Early identification of these indicators can result in early remedy to prevent the forthcoming diseases. With this aim a cross sectional study was planned to develop a scale for the assessment of HRQOL in the persons consuming unhealthy food habits. Objectives of the Study: To develop a validated scale to assess the HRQOL in healthy individuals who have unhealthy food habits. Methods: All the data regarding the components which are taken as an indicator of HRQOL were compiled and critically analyzed for construction of the domains and item generation. The content validity was carried out by giving to 5 experts as a process of pretesting of the questionnaire and for checking the face value. Questionnaire administration was done on 77 healthy subjects as a first set of analysis and later on 111 healthy subjects development and validation. For internal consistency Cronbach’s alpha was run, & for item reduction Principal component analysis (PCA) was done and components were extracted and accordingly domains were reframed. Reframed questionnaire was administered to the 270 healthy subjects and to check reliability Cronbach’s alpha was done. Scoring was done based on the mean of all domains to create the scale. Results: Initially 104 items were framed based on the intense literature search, after content validity no items were deleted. So, 104 questions were administered for 1st assessment after checking the internal consistency 28 items were deleted and 76 items remained. After the 2nd set of assessment with deletion of 7 items 69 items remained. After data extraction 43 items remained which were used for the generation of the scale scoring. The scoring was done based on the mean of all the domains. Conclusion: This developed self-assessment scale will help in the assessment of effect of unhealthy food habits over the HRQOL in apparently healthy subjects. This will give the scoring for the HRQOL which was calculated based on the mean of all the domains