Is nonlinear propagation responsible for the brassiness of elephant trumpet calls?

African elephants (Loxodonta africana) produce a broad diversity of sounds ranging from infrasonic rumbles to much higher frequency trumpets. Trumpet calls are very loud voiced signals given by highly aroused elephants, and appear to be produced by a forceful expulsion of air through the trunk. Some trumpet calls have a very distinctive quality that is unique in the animal kingdom, but resemble the "brassy" sounds that can be produced with brass musical instruments such as trumpets or trombones. Brassy musical sounds are characterised by a flat spectral slope caused by the nonlinear propagation of the source wave as it travels through the long bore of the instrument. The extent of this phenomenon, which normally occurs at high intensity levels (e.g. fortissimo), depends on the fundamental frequency (F0) of the source as well as on the length of the resonating tube. Interestingly, the length of the vocal tract of the elephant (as measured from the vocal folds to the end of the trunk) approximates the critical length for shockwave formation, given the fundamental frequency and intensity of trumpet calls. We suggest that this phenomenon could explain the unique, distinctive brassy quality of elephant trumpet calls

Shared larval rearing environment, sex, female size and genetic diversity shape Ae. albopictus bacterial microbiota

The Asian tiger mosquito Aedes albopictus became of public health concern as it can replicate and transmit viral and filarial pathogens with a strong invasive success over the world. Various strategies have been proposed to reduce mosquito population's vectorial capacity. Among them, symbiotic control of mosquito borne disease offers promising perspectives. Such method is likely to be affected by the dynamics of mosquito-associated symbiotic communities, which might in turn be affected by host genotype and environment. Our previous study suggested a correlation between mosquitoes' origin, genetic diversity and midgut bacterial diversity. To distinguish the impact of those factors, we have been studying the midgut bacterial microbiota of two Ae. albopictus populations from tropical (La Re A union) and temperate (Montpellier) origins under controlled laboratory conditions. the two populations experienced random mating or genetic bottleneck. Microbiota composition did not highlight any variation of the alpha and beta-diversities in bacterial communities related to host's populations. However, sizes of the mosquitoes were negatively correlated with the bacterial a-diversity of females. Variations in mosquito sex were associated with a shift in the composition of bacterial microbiota. The females' mosquitoes also exhibited changes in the microbiota composition according to their size and after experiencing a reduction of their genetic diversity. These results provide a framework to investigate the impact of population dynamics on the symbiotic communities associated with the tiger mosquito.Peer reviewe

Laboratory demonstration of the triple-grating vector vortex coronagraph

The future Habitable Worlds Observatory aims to characterize the atmospheres of rocky exoplanets around solar-type stars. The vector vortex coronagraph (VVC) is a main candidate to reach the required contrast of $10^{-10}$. However, the VVC requires polarization filtering and every observing band requires a different VVC. The triple-grating vector vortex coronagraph (tgVVC) aims to mitigate these limitations by combining multiple gratings that minimize the polarization leakage over a large spectral bandwidth. In this paper, we present laboratory results of a tgVVC prototype using the In-Air Coronagraphic Testbed (IACT) facility at NASA's Jet Propulsion Laboratory and the Space Coronagraph Optical Bench (SCoOB) at the University of Arizona Space Astrophysics Lab (UASAL). We study the coronagraphic performance with polarization filtering at 633 nm and reach a similar average contrast of $2 \times 10^{-8}$ between 3-18 $\lambda/D$ at the IACT, and $6 \times 10^{-8}$ between 3-14 $\lambda/D$ at SCoOB. We explore the limitations of the tgVVC by comparing the testbed results. We report on other manufacturing errors and ways to mitigate their impact.Comment: 9 pages, 5 figures, SPIE Optics + Photonics - Techniques and Instrumentation for Detection of Exoplanets X

Rapid design and manufacture tools in architecture

The continuing development of rapid prototyping technologies and the introduction of concept modelling technologies means that their use is expanding into a greater range of applications. The primary aim of this paper is to give the reader an overview of the current state of the art in layered manufacturing (LM) technology and its applicability in the field of architecture. The paper reports on the findings of a benchmarking study, conducted by the Rapid Design and Manufacturing (RDM) Group in Glasgow [G.J. Ryder, A. McGown, W. Ion, G. Green, D. Harrison, B. Wood, Rapid prototyping feasibility report, Rapid Prototyping Group, Glasgow School of Art, 1998.], which identified that the applicability of LM technologies in any application can be governed by a series of critical process and application specific issues. A further survey carried out by the RDM group investigated current model making practice, current 3D CAD use and current use of LM technologies within the field of architecture. The findings are then compared with the capabilities of LM technologies. Future research needs in this area are identified and briefly outlined

Adaptive optics performance of a simulated coronagraph instrument on a large, segmented space telescope in steady state

Directly imaging Earth-like exoplanets (``exoEarths'') with a coronagraph instrument on a space telescope requires a stable wavefront with optical path differences limited to tens of picometers RMS during exposure times of a few hours. While the structural dynamics of a segmented mirror can be directly stabilized with telescope metrology, another possibility is to use a closed-loop wavefront sensing and control system in the coronagraph instrument that operates during the science exposures to actively correct the wavefront and relax the constraints on the stability of the telescope. In this paper, we present simulations of the temporal filtering provided using the example of LUVOIR-A, a 15~m segmented telescope concept. Assuming steady-state aberrations based on a finite element model of the telescope structure, we (1)~optimize the system to minimize the wavefront residuals, (2)~ use an end-to-end numerical propagation model to estimate the residual starlight intensity at the science detector, and (3)~predict the number of exoEarth candidates detected during the mission. We show that telescope dynamic errors of 100~pm~RMS can be reduced down to 30~pm~RMS with a magnitude 0 star, improving the contrast performance by a factor of 15. In scenarios where vibration frequencies are too fast for a system that uses natural guide stars, laser sources can increase the flux at the wavefront sensor to increase the servo-loop frequency and mitigate the high temporal frequency wavefront errors. For example, an external laser with an effective magnitude of -4 allows the wavefront from a telescope with 100~pm~RMS dynamic errors and strong vibrations as fast as 16~Hz to be stabilized with residual errors of 10~pm~RMS thereby increasing the number of detected planets by at least a factor of 4.Comment: Published in JATIS. arXiv admin note: substantial text overlap with arXiv:2108.0640

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

AIMS: Extracellular matrix remodelling has been implicated in a number of vascular conditions, including venous hypertension and varicose veins. However, to date, no systematic analysis of matrix remodelling in human veins has been performed. METHODS AND RESULTS: To understand the consequences of venous hypertension, normal and varicose veins were evaluated using proteomics approaches targeting the extracellular matrix. Varicose saphenous veins removed during phlebectomy and normal saphenous veins obtained during coronary artery bypass surgery were collected for proteomics analysis. Extracellular matrix proteins were enriched from venous tissues. The proteomics analysis revealed the presence of >150 extracellular matrix proteins, of which 48 had not been previously detected in venous tissue. Extracellular matrix remodelling in varicose veins was characterized by a loss of aggrecan and several small leucine-rich proteoglycans and a compensatory increase in collagen I and laminins. Gene expression analysis of the same tissues suggested that the remodelling process associated with venous hypertension predominantly occurs at the protein rather than the transcript level. The loss of aggrecan in varicose veins was paralleled by a reduced expression of aggrecanases. Chymase and tryptase β1 were among the up-regulated proteases. The effect of these serine proteases on the venous extracellular matrix was further explored by incubating normal saphenous veins with recombinant enzymes. Proteomics analysis revealed extensive extracellular matrix degradation after digestion with tryptase β1. In comparison, chymase was less potent and degraded predominantly basement membrane-associated proteins. CONCLUSION: The present proteomics study provides unprecedented insights into the expression and degradation of structural and regulatory components of the vascular extracellular matrix in varicosis