Proceedings of the 33rd Annual Meeting, Southern Soybean Disease Workers (March 8-9, 2006, Jackson, Tennessee)

Contents Southern Soybean Disease Workers 2005 treasury report Southern United States Soybean Disease Loss Estimates for 2005. Compiled by SR Koenning Virulence in Phytopbthora sojae Isolates to Soybeans with Rps8 Resistance. DA Smith, TS Abney, and JG Shannon New Sources of Resistance to SCN in Soybean. PR Arelli Soybean Disease Management in Louisiana. B Padgett, MA Purvis, and BW Garber Efficacy and Profitability of Foliar Fungicide in the Absence of Soybean Rust. M Newman and W Percell Fungicide and Insecticide Combinations for Enhancing Soybean Health and Yield. RP Mulrooney and RW Taylor Overview of Soybean Rust Monitoring in the US. JC Rupe Yield Enhancement of Probable Asian Soybean Rust Control Fungicides. JB Blessitt, DH Poston, GL Sciumbato, CH Koger, and N Buehring Occurrence of Disease and Insect Pests in Select Sorghum and Soybean Rotations in Mississippi. ST Pichardo, RE Baird, and HN Pitre A Preliminary Evaluation of Spore Trapping Technology for Phakopsora pachyrhizi. EP Mumma, RW Schneider, CL Robertson, CG Giles, JJ Marois, and DL Wright Influence of Host Genotype and Soybean Cyst Nematode on Charcoal Rot of Soybean. TM Dorton, JP Bond, ME Schmidt, CM Vick, and AK Gregor Comparison of Disease Assessments of Soybean Genotypes in the Presence of Charcoal Rot. A Mengistu, RL Paris, JR Smith, and JD Ray Twenty Years of Soybean Variety Testing for SDS. C Schmidt, J Klein, M Schmidt, and J Bond SCN-Resistant Soybeans Offer a False Sense of Security to Producers. R Heinz, LE Sweets, and MG Mitchum Roundup Ready and Conventional Soybeans with Broad Resistance to SCN HG Types. JG Shannon, JA Wrather, DA Sleper, HT Nguyen, and SC Anand A Review ofReniform Nematode Resistance on Soybean. RT Robbins Effect of Seed Treatments on Soybean Stand and Yield in Arkansas, 2005. JC Rupe, CS Rothrock, TL Kirkpatrick, ML Rosso, and AJ Steger Inheritance of Resistance to Phomopsis Seed Decay in Soybean PI 360841. SE Smith, P Fenn, PK Miller, and P Chen Proceedings of the Southern Soybean Disease Workers are published annually by the Southern Soybean Disease Workers. Text, references, figures, and tables are reproduced as they were submitted by authors. The opinions expressed by the participants at this conference are their own and do not necessarily represent those of the Southern Soybean Disease Workers. Mention of a trademark or proprietary products in this publication does not constitute a guarantee, warranty, or endorsement of that product by the Southern Soybean Disease Workers

Proceedings of the 35th Annual Meeting, Southern Soybean Disease Workers (March 12-13, 2008, Pensacola, Florida)

Contents Southern United States Soybean Disease Loss Estimate for 2007. Compiled by SR Koenning Contributed papers (Clayton Hollier, moderator) Effects of Row Spacing and Leaf Wetness on the Temporal and Spatial Spread of Soybean Rust within Soybean Canopies. DF Narváez, JJ Marois, DL Wright, and S Isard Effects of Potassium, Chloride, and Minor Elements Nutrition on Asian Soybean Rust. RW Schneider, EP Mumma, CL Clark, and CG Giles The Impact of Selected Fungicide Treatments on Disease Progress of Asian Soybean Rust and Other Diseases of Soybean. GB Padgett, MA Purvis, A Hogan, and S Martin Soybean Sudden Death Syndrome Variety Testing at Southern Illinois University. C Herzog, C Schmidt, and M Schmidt Soybean Yield Suppression Due to Diseases for the Top Eight Soybean-Producing Countries in 2006. A Wrather, S Koenning, R Balardin, LH Carregal, R Escobar, GK Gupta, Z Ma, W Morel, LD Ploper, and A Tenuta Impact of Frogeye Leaf Spot on Soybean Yield in the Lower Midwest. CM Vick, AK Vick, JP Bond, and JA Wrather Graduate student papers (Alemu Mengistu, moderator) Laboratory Evaluation of Soybean Resistance to Pod Blight Caused by Cercospora kikuchii. BC Wells and GL Sciumbato Temporal Dynamics of Root and Foliar Symptoms of Soybean Sudden Death Syndrome at Different Inoculum Densities. C Gongora-Canul, FW Nutter, Jr, and LFS Leandro Discussion session (Allen Wrather, moderator) Soybean Rust Sentinal Survey discussion. Don Hershman Proceedings of the Southern Soybean Disease Workers are published annually by the Southern Soybean Disease Workers. Text, references, figures, and tables are reproduced as they were submitted by authors. The opinions expressed by the participants at this conference are their own and do not necessarily represent those of the Southern Soybean Disease Workers. Mention of a trademark or proprietary products in this publication does not constitute a guarantee, warranty, or endorsement of that product by the Southern Soybean Disease Workers

The Victorian Newsletter (Spring 1960)

The Victorian Newsletter is edited for the English X Group of the Modern Language Association by William E. Buckler, 737 East Building, New York University, New York 3, New York

LICC: L-BLP25 in patients with colorectal carcinoma after curative resection of hepatic metastases--a randomized, placebo-controlled, multicenter, multinational, double-blinded phase II trial

Background: 15-20% of all patients initially diagnosed with colorectal cancer develop metastatic disease and surgical resection remains the only potentially curative treatment available. Current 5-year survival following R0-resection of liver metastases is 28-39%, but recurrence eventually occurs in up to 70%. To date, adjuvant chemotherapy has not improved clinical outcomes significantly. The primary objective of the ongoing LICC trial (L-BLP25 In Colorectal Cancer) is to determine whether L-BLP25, an active cancer immunotherapy, extends recurrence-free survival (RFS) time over placebo in colorectal cancer patients following R0/R1 resection of hepatic metastases. L-BLP25 targets MUC1 glycoprotein, which is highly expressed in hepatic metastases from colorectal cancer. In a phase IIB trial, L-BLP25 has shown acceptable tolerability and a trend towards longer survival in patients with stage IIIB locoregional NSCLC. Methods: This is a multinational, phase II, multicenter, randomized, double-blind, placebo-controlled trial with a sample size of 159 patients from 20 centers in 3 countries. Patients with stage IV colorectal adenocarcinoma limited to liver metastases are included. Following curative-intent complete resection of the primary tumor and of all synchronous/metachronous metastases, eligible patients are randomized 2:1 to receive either L-BLP25 or placebo. Those allocated to L-BLP25 receive a single dose of 300 mg/m2 cyclophosphamide (CP) 3 days before first L-BLP25 dose, then primary treatment with s.c. L-BLP25 930 mug once weekly for 8 weeks, followed by s.c. L-BLP25 930 mug maintenance doses at 6-week (years 1&2) and 12-week (year 3) intervals unless recurrence occurs. In the control arm, CP is replaced by saline solution and L-BLP25 by placebo. Primary endpoint is the comparison of recurrence-free survival (RFS) time between groups. Secondary endpoints are overall survival (OS) time, safety, tolerability, RFS/OS in MUC-1 positive cancers. Exploratory immune response analyses are planned. The primary endpoint will be assessed in Q3 2016. Follow-up will end Q3 2017. Interim analyses are not planned. Discussion: The design and implementation of such a vaccination study in colorectal cancer is feasible. The study will provide recurrence-free and overall survival rates of groups in an unbiased fashion. Trial Registration EudraCT Number 2011-000218-2

Multiple Resistance of Horseweed to Glyphosate and Paraquat and Its Control with Paraquat and Metribuzin Combinations

Greenhouse and field studies were conducted in 2007 and 2008 to investigate possible multiple-resistance of horseweed to paraquat and glyphosate, and to evaluate the effect of the addition of metribuzin to paraquat on control of paraquat-resistant horseweed. Results indicated that the GR50 (herbicide dose required to cause a 50% reduction in plant growth) value for the susceptible population S102 was 0.066 kg ae/ha glyphosate, and for the resistant population MDOT was 0.78 kg/ha glyphosate. The level of glyphosate resistance for MDOT was 12-fold compared with S102. The GR50 value for the susceptible population S102 was 0.078 kg ai/ha paraquat, and for the resistant population MDOT was 0.67 kg/ha paraquat. The level of paraquat resistance for MDOT was 9-fold compared to S102, suggesting multiple-resistance to glyphosate and paraquat in the MDOT population. In field studies the addition of metribuzin to paraquat improved horseweed control

Proceedings of the 34th Annual Meeting of the Southern Soybean Disease Workers (February 18-19, 2007, St. Louis, Missouri)

Southern United States Soybean Disease Loss Estimates for 2006. SR Koenning Stratego 250 EC, Broad Spectrum Disease Control in Soybeans. JR Bloomberg, RA Myers, and R Kraus Asian Soybean Rust: Efficacy of Selected Fungicides and Observations on Their Use. RW Schneider, CL Clark, EP Mumma, and CG Giles Effects of Light Intensity and Darkness Period on Infection of Soybean Rust in Controlled Conditions. J Mo, T Guo, X Li, and XB Yang Identification of Maturity Group 3 and 4 Soybean Cultivars and Lines Resistant to Cercospora sojina by Field Screening and Molecular Markers. A Wrather, R Mian, G Shannon, J Bond, M Newman, and W Wiebold Phytophthora Resistance of Soybean Germplasm with High Potential for Asian Soybean Rust Resistance. DA Smith, TS Abney, and A Westphal SBR PIPE Workshop: Discussion of new features for the 2007 PIPE that will impact SBR observers and specialists. S Isard, J Golod, L Sconyers, and D Hershman Soybean Cultivar Disease Reaction to Inoculation with Diaporthe phaseolorum var. meridionalis, 2000-2006. B Wells and G Sciumbato Molecular Tools to Study the F. solani f.sp glycines-Soybean Interaction. S Mansouri and AM Fakhoury Inheritance and Genetic Mapping of Resistance to Pythium Damping-off caused by Pythium aphanidermatum in Soybean Cultivar Archer. ML Rosso, JC Rupe, CS Rothrock, and P Chen New Hosts to Phakopsora pachyrhizi Identified in Quincy, Florida. TL Slaminko Impact of Fungicide and Defoliation Timing on Disease Control and Soybean Uield. JB Blessitt, DH Poston, GL Sciumbato, RT Coleman, HC Doty, S Kyei-Boahiem, TW Eubank, and BL Spinks Effects of Post-inoculation Night Length and Daytime Light Intensity on Asian Soybean Rust Development. APS Dias, XB Yang, PF Harmon, and CL Harmon Foliar Fungicides: Timing of Application and Cultivar Reactions. MA Newman, W Percell, and R Zawacki Managing Asian Soybean Rust in Louisiana: The First Year. GB Padgett, RW Schneider, CA Hollier, A Hogan, MA Purvis, and C Robertson Modeling Light Intensity Patterns to Estimate Soybean Rust Outbreaks: Comparative Analysis in Brazil and South Africa. APS Dias, XB Yang, and X Li Southern Soybean Disease Workers 2006 Treasury Report. JP Bond Proceedings of the Southern Soybean Disease Workers are published annually by the Southern Soybean Disease Workers. Text, references, figures, and tables are reproduced as they were submitted by authors. The opinions expressed by the participants at this conference are their own and do not necessarily represent those of the Southern Soybean Disease Workers. Mention of a trademark or proprietary products in this publication does not constitute a guarantee, warranty, or endorsement of that product by the Southern Soybean Disease Workers