Co-evolutionary dynamics in strategic alliances : the influence of the industry lifecycle

This study examines the application of the co-evolution literature to strategic alliance formation in SME’s in the UK and Australia in two differing industries at different stages of the industry life-cycle. Extending the framework developed by Das and Teng (2002) and that of Wilson and Hynes (2009), it engages with wider industry and environmental characteristics present in these two countries, specifically examining whether different theories of alliance formation are better suited to different stages of an industry life cycle. The issues discussed above are explored and developed through the use of a qualitative case study approach. Findings indicate strong resource-based drivers for alliance formation in both industries, with firms dependent on the co-evolution of their alliances and indeed selected by the results of their alliance participation. However, differences emerged in the strategic use of alliances in these two industries. The influence of the stage of the industry life cycle on this is discussed

Experimental evolution of olfactory memory in Drosophila melanogaster

In order to address the nature of genetic variation in learning performance, we investigated the response to classical olfactory conditioning in "high-learning" Drosophila melanogaster lines previously subject to selection for the ability to learn an association between the flavor of an oviposition medium and bitter taste. In a T-maze choice test, the seven high-learning lines were better at avoiding an odor previously associated with aversive mechanical shock than were five unselected "low-learning" lines originating from the same natural population. Thus, the evolved improvement in learning ability of high-learning lines generalized to another aversion learning task involving a different aversive stimulus (shock instead of bitter taste) and a different behavioral context than that used to impose selection. In this olfactory shock task, the high-learning lines showed improvements in the learning rate as well as in two forms of consolidated memory: anesthesia-resistant memory and long-term memory. Thus, genetic variation underlying the experimental evolution of learning performance in the high-learning lines affected several phases of memory formation in the course of olfactory aversive learning. However, the two forms of consolidated memory were negatively correlated among replicate high-learning lines, which is consistent with a recent hypothesis that these two forms of consolidated memory are antagonistic

Bioindication : des outils pour évaluer l'état écologique des milieux aquatiques - Perspectives en vue du 2e cycle DCE - Eaux de surface continentales

[Departement_IRSTEA]Eaux [TR1_IRSTEA]QUASARE [TR2_IRSTEA]BELCAAprès une présentation des besoins en matière d'évaluation de la qualité des milieux aquatiques continentaux, ce document présente l'état de l'art sur le développement des bioindicateurs tels qu'il a été présenté lors du séminaire organisé par l'Onema les 19 et 20 avril 2011 à Paris. Il s'agit donc d'une synthèse des journées "DCE et bioindication

Difficult tracheal intubation in neonates and infants. NEonate and Children audiT of Anaesthesia pRactice IN Europe (NECTARINE): a prospective European multicentre observational study

International audienceBackground: Neonates and infants are susceptible to hypoxaemia in the perioperative period. The aim of this study was to analyse interventions related to anaesthesia tracheal intubations in this European cohort and identify their clinical consequences.Methods: We performed a secondary analysis of tracheal intubations of the European multicentre observational trial (NEonate and Children audiT of Anaesthesia pRactice IN Europe [NECTARINE]) in neonates and small infants with difficult tracheal intubation. The primary endpoint was the incidence of difficult intubation and the related complications. The secondary endpoints were the risk factors for severe hypoxaemia attributed to difficult airway management, and 30 and 90 day outcomes.Results: Tracheal intubation was planned in 4683 procedures. Difficult tracheal intubation, defined as two failed attempts of direct laryngoscopy, occurred in 266 children (271 procedures) with an incidence (95% confidence interval [CI]) of 5.8% (95% CI, 5.1-6.5). Bradycardia occurred in 8% of the cases with difficult intubation, whereas a significant decrease in oxygen saturation (SpO2<90% for 60 s) was reported in 40%. No associated risk factors could be identified among co-morbidities, surgical, or anaesthesia management. Using propensity scoring to adjust for confounders, difficult anaesthesia tracheal intubation did not lead to an increase in 30 and 90 day morbidity or mortality.Conclusions: The results of the present study demonstrate a high incidence of difficult tracheal intubation in children less than 60 weeks post-conceptual age commonly resulting in severe hypoxaemia. Reassuringly, the morbidity and mortality at 30 and 90 days was not increased by the occurrence of a difficult intubation event