10 research outputs found
Bioactive versus bare platinum coils for the endovascular treatment of intracranial aneurysms: systematic review and meta-analysis of randomized clinical trials
Periprocedural Safety and Feasibility of the New LVIS EVO Device for Stent-Assisted Coiling of Intracranial Aneurysms: An Observational Multicenter Study
BACKGROUND AND PURPOSE: Stent-assisted treatment techniques can be an effective treatment option for intracranial aneurysms. The aim of this study was to evaluate the periprocedural feasibility and safety of the new LVIS EVO stent for the treatment of intracranial aneurysms. MATERIALS AND METHODS: Patients with intracranial aneurysms treated with the LVIS EVO in 11 European neurovascular centers were retrospectively reviewed. Patient and aneurysm characteristics, procedural parameters, immediate grade of occlusion, and technical and clinical complications were assessed. RESULTS: Fifty-seven patients with 59 aneurysms were treated with the LVIS EVO device; 57.6% of the aneurysms were incidental; 15.3% were acutely ruptured; 15.3% were recanalized or residual aneurysms; and 11.9% were treated for symptoms other than acute hemorrhage. The most frequent aneurysm locations were the middle cerebral artery (25.4%) and the anterior communicating artery (22.0%). The rate of immediate successful deployment was 93.2%. In 6.8% (n = 4) of cases, additional in-stent angioplasty was needed. The immediate complete occlusion rate was 54.2%, while there was a residual aneurysm in 35.6% and a residual neck in 10.2%. Periprocedural technical complications occurred in 7/59 treatments (11.9%; the most frequent technical complication [n = 3] was thrombus formation), which all resolved completely without clinical sequelae. Postprocedural neurologic complications occurred after 4/59 treatments (6.8%; 2 transient ischemic attacks, 1 minor stroke, 1 major stroke), of which only 1 persistent complication was directly related to the procedure (minor stroke in the vascular territory distal to the stent). CONCLUSIONS: The LVIS EVO stent is a safe, feasible device for the treatment of intracranial aneurysms
Safety and Efficacy of Ultra-high-dose, Short-term Thrombolysis with rt-PA for Acute Lower Limb Ischemia
Efficient simulation of a low-profile visualized intraluminal support device: a novel fast virtual stenting technique
Hydrogel coils versus bare platinum coils for the endovascular treatment of intracranial aneurysms: a meta-analysis of randomized controlled trials
Cosmic-Ray Extremely Distributed Observatory
The Cosmic-Ray Extremely Distributed Observatory (CREDO) is a newly formed,
global collaboration dedicated to observing and studying cosmic rays (CR) and cosmic-ray ensembles
(CRE): groups of at least two CR with a common primary interaction vertex or the same parent particle.
The CREDO program embraces testing known CR and CRE scenarios, and preparing to observe
unexpected physics, it is also suitable for multi-messenger and multi-mission applications. Perfectly
matched to CREDO capabilities, CRE could be formed both within classical models (e.g., as products
of photon–photon interactions), and exotic scenarios (e.g., as results of decay of Super-Heavy Dark
Matter particles). Their fronts might be significantly extended in space and time, and they might
include cosmic rays of energies spanning the whole cosmic-ray energy spectrum, with a footprint
composed of at least two extensive air showers with correlated arrival directions and arrival times.
As the CRE are predominantly expected to be spread over large areas and, due to the expected wide
energy range of the contributing particles, such a CRE detection might only be feasible when using
all available cosmic-ray infrastructure collectively, i.e., as a globally extended network of detectors.
Thus, with this review article, the CREDO Collaboration invites the astroparticle physics community
to actively join or to contribute to the research dedicated to CRE and, in particular, to pool together
cosmic-ray data to support specific CRE detection strategies