34 research outputs found

    Low back pain around retirement age and physical occupational exposure during working life

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    <p>Abstract</p> <p>Background</p> <p>Physical occupational exposure is a risk factor for low back pain in workers but the long term effects of exposure remain unclear. As several countries consider increasing the retirement age, further information on this topic is relevant. This study aimed to describe the prevalence of low back pain among middle aged and aging individuals in the general French population according to physical occupational exposure and retirement status.</p> <p>Methods</p> <p>The study population originated from the French national survey 'Enquête décennale santé 2002'. Low back pain for more than 30 days within the previous twelve months (LBP) was assessed using a French version of the Nordic questionnaire. Occupational exposure was self assessed. Subjects were classified as "exposed" if they were currently or had previously been exposed to handling of heavy loads and/or to tiring postures. The weighted prevalence of LBP was computed separately for men and women, for active (aged 45-59) and retiree (aged 55-74), according to 5-year age group and past/present occupational exposure.</p> <p>Results</p> <p>For active men, the prevalence of LBP was significantly higher in those currently or previously exposed (n = 1051) compared with those never exposed (n = 1183), respectively over 20% versus less than 11%. Among retired men, the prevalence of LBP tended towards equivalence with increasing age among those previously exposed (n = 748) and those unexposed (n = 599).</p> <p>Patterns were quite similar for women with a higher prevalence in exposed active women (n = 741) compared to unexposed (n = 1260): around 25% versus 15%. Similarly, differences between previously exposed (n = 430) and unexposed (n = 489) retired women tended to reduce with age.</p> <p>Conclusion</p> <p>The prevalence of LBP in active workers was associated with occupational exposure. The link with past exposure among retirees decreased with age. These results should be considered for policies dealing with prevention at the workplace and retirement.</p

    Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome associated with COVID-19: An Emulated Target Trial Analysis.

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    RATIONALE: Whether COVID patients may benefit from extracorporeal membrane oxygenation (ECMO) compared with conventional invasive mechanical ventilation (IMV) remains unknown. OBJECTIVES: To estimate the effect of ECMO on 90-Day mortality vs IMV only Methods: Among 4,244 critically ill adult patients with COVID-19 included in a multicenter cohort study, we emulated a target trial comparing the treatment strategies of initiating ECMO vs. no ECMO within 7 days of IMV in patients with severe acute respiratory distress syndrome (PaO2/FiO2 <80 or PaCO2 ≥60 mmHg). We controlled for confounding using a multivariable Cox model based on predefined variables. MAIN RESULTS: 1,235 patients met the full eligibility criteria for the emulated trial, among whom 164 patients initiated ECMO. The ECMO strategy had a higher survival probability at Day-7 from the onset of eligibility criteria (87% vs 83%, risk difference: 4%, 95% CI 0;9%) which decreased during follow-up (survival at Day-90: 63% vs 65%, risk difference: -2%, 95% CI -10;5%). However, ECMO was associated with higher survival when performed in high-volume ECMO centers or in regions where a specific ECMO network organization was set up to handle high demand, and when initiated within the first 4 days of MV and in profoundly hypoxemic patients. CONCLUSIONS: In an emulated trial based on a nationwide COVID-19 cohort, we found differential survival over time of an ECMO compared with a no-ECMO strategy. However, ECMO was consistently associated with better outcomes when performed in high-volume centers and in regions with ECMO capacities specifically organized to handle high demand. This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/)

    Low back pain, age and occupational exposure

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    Les effets à court ou moyen terme de certaines expositions professionnelles biomécaniques sur lerisque de lombalgie sont reconnus. Les effets à long terme sont moins connus. Ces expositionscontribuent aux inégalités sociales de lombalgies,mais ceci est peu documenté une fois la carrièreterminée.Dans un contexte de débat sur l’âge de la retraite et la prise en compte de la pénibilité au travail,l'objectif de cette thèse était d'apporter des éléments de connaissances sur les liens entreexposition aux risques professionnels physiques et lombalgies autour de l’âge de la retraite, ainsique sur la présence d'inégalités sociale de lombalgies parmi des actifs vieillissants et des retraitéset la contribution de ces expositions à ces inégalités.Les lombalgies ayant duré plus de 30 jours au cours des 12 mois précédents ont été étudiéesdans la cohorte Gazel et l'Enquête Décennale Santé 2002 (EDS).Des arguments en faveur de la persistance des effets d'expositions physiques professionnelles audelà de la période d'activité ont été trouvés. Les données de l’EDS suggèrent que ces effetss’estomperaient au-delà d’un certain âge.Les expositions professionnelles, en particulier biomécaniques, jouent un rôle majeur dans lesinégalités sociales de lombalgies chez les hommes de la cohorte Gazel, actifs vieillissants etjeunes retraités. Par contre, de telles inégalités ne sont pas observées chez les retraités de 60 à74 ans de l'EDS.Ce travail montre l'importance en matière de lombalgies persistantes/récidivantes d'expositionsprofessionnelles a priori accessibles à une démarche de prévention, et l'intérêt de considérer leparcours professionnel dans les politiques de retraiteSome biomechanical exposures at work are recognized short term risk factors for low back pain(LBP). However, long term effects, are not well known. In addition, occupational exposures seemto contribute to social inequalities in low back pain, but this contribution is less documented forolder subjects.In many developed countries, governments are now reconsidering retirement policies. In thiscontext, the objective of this work was firstly to provide additional knowledge about the linksbetween physical exposure and LBP among aging workers and retirees, and secondly to assesssocial inequalities in LBP in this age group and the contribution of occupational factors to suchinequalities.Two populations were studied : volunteers from the Gazel cohort and participants to a Frenchnational survey on health (EDS 2002). The same definition for LBP could be used in bothpopulations : LBP which lasted more than 30 days in the previous 12 months.LBP was associated with physical occupational exposures among aging workers and youngretirees in both populations. Results were consistent with the hypothesis of a persistence of effectsonce occupational exposure has ceased, except among the oldest retirees in the EDS 2002.Biomechanical exposures played a major role in social inequalities for LBP among aging workersand young retirees in the GAZEL cohort. Such inequalities were not observed among the retireesaged 60 to 74 years (men and women) from the EDS 2002.The results highlight the importance of past occupational exposures at retirement age

    Impact de facteurs professionnels sur le spermogramme

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    LILLE2-BU Santé-Recherche (593502101) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

    Lombalgies, âge et expositions professionnelles

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    Les effets à court ou moyen terme de certaines expositions professionnelles biomécaniques sur lerisque de lombalgie sont reconnus. Les effets à long terme sont moins connus. Ces expositionscontribuent aux inégalités sociales de lombalgies,mais ceci est peu documenté une fois la carrièreterminée.Dans un contexte de débat sur l âge de la retraite et la prise en compte de la pénibilité au travail,l'objectif de cette thèse était d'apporter des éléments de connaissances sur les liens entreexposition aux risques professionnels physiques et lombalgies autour de l âge de la retraite, ainsique sur la présence d'inégalités sociale de lombalgies parmi des actifs vieillissants et des retraitéset la contribution de ces expositions à ces inégalités.Les lombalgies ayant duré plus de 30 jours au cours des 12 mois précédents ont été étudiéesdans la cohorte Gazel et l'Enquête Décennale Santé 2002 (EDS).Des arguments en faveur de la persistance des effets d'expositions physiques professionnelles audelà de la période d'activité ont été trouvés. Les données de l EDS suggèrent que ces effetss estomperaient au-delà d un certain âge.Les expositions professionnelles, en particulier biomécaniques, jouent un rôle majeur dans lesinégalités sociales de lombalgies chez les hommes de la cohorte Gazel, actifs vieillissants etjeunes retraités. Par contre, de telles inégalités ne sont pas observées chez les retraités de 60 à74 ans de l'EDS.Ce travail montre l'importance en matière de lombalgies persistantes/récidivantes d'expositionsprofessionnelles a priori accessibles à une démarche de prévention, et l'intérêt de considérer leparcours professionnel dans les politiques de retraiteSome biomechanical exposures at work are recognized short term risk factors for low back pain(LBP). However, long term effects, are not well known. In addition, occupational exposures seemto contribute to social inequalities in low back pain, but this contribution is less documented forolder subjects.In many developed countries, governments are now reconsidering retirement policies. In thiscontext, the objective of this work was firstly to provide additional knowledge about the linksbetween physical exposure and LBP among aging workers and retirees, and secondly to assesssocial inequalities in LBP in this age group and the contribution of occupational factors to suchinequalities.Two populations were studied : volunteers from the Gazel cohort and participants to a Frenchnational survey on health (EDS 2002). The same definition for LBP could be used in bothpopulations : LBP which lasted more than 30 days in the previous 12 months.LBP was associated with physical occupational exposures among aging workers and youngretirees in both populations. Results were consistent with the hypothesis of a persistence of effectsonce occupational exposure has ceased, except among the oldest retirees in the EDS 2002.Biomechanical exposures played a major role in social inequalities for LBP among aging workersand young retirees in the GAZEL cohort. Such inequalities were not observed among the retireesaged 60 to 74 years (men and women) from the EDS 2002.The results highlight the importance of past occupational exposures at retirement age.PARIS11-SCD-Bib. électronique (914719901) / SudocSudocFranceF

    Biomechanical strains and low back disorders: quantifying the effects of the number of years of exposure on various types of pain.

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    International audienceOBJECTIVE: To assess the effects of duration of exposure to biomechanical strains on various types of low back pain (LBP). METHODS: The population study was a random sample from the GAZEL cohort. Durations of exposure to selected biomechanical strains during subjects' working lifetime and potential confounders were assessed in 1996 by self-administered questionnaires. Data on LBP in the previous 12 months were collected in 2001. Relations between various dimensions of LBP and durations of exposure to the biomechanical strains were analysed with multivariate regression models. Polytomous models were built to determine whether some biomechanical strains were specifically associated with some types of LBP. RESULTS: Analyses were performed separately for men (n = 2218) and women (n = 383). Significant associations were observed (ORs reported are those for 20 years of exposure) between LBP and durations of driving and bending/twisting for men (OR 1.24 and 1.37 respectively); LBP for more than 30 days and duration of exposure to bending/twisting for men and women (OR 2.20 and 2.00 respectively) and duration of driving for women (OR 3.15); LBP radiating to the leg and duration of driving for men (OR 1.43) and bending/twisting for women (OR 1.95); LBP radiating below the knee and duration of exposure to pulling/pushing/carrying for men (OR 1.88). Bending/twisting in both men and women, and driving for women appeared to be stronger risk factors for LBP for more than 30 days. Pulling/pushing/carrying heavy loads appeared to be a risk factor specific for LBP radiating below the knee for men. CONCLUSION: This study suggests that exposure to biomechanical strains has long-term effects and a dose-response relation with duration of exposure and specific effects for some types of LBP

    Socioeconomic position and low-back pain--the role of biomechanical strains and psychosocial work factors in the GAZEL cohort.

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    International audienceOBJECTIVE: To analyze the role that biomechanical strains and psychosocial work factors play in occupational class disparities in low-back pain in the GAZEL cohort. METHODS: Recruited in 1989, the GAZEL cohort members were employees of the French national company in charge of energy who volunteered to enroll in an annual follow-up survey. The study population comprised 1487 men who completed questionnaires in 1996 (past occupational exposure to manual material handling, bending/twisting, and driving), 1997 (psychosocial work factors), and 2001 (low-back pain using a French version of the Nordic questionnaire for the assessment of low-back pain). Associations between low-back pain for >30 days in the preceding 12 months and social position at baseline (four categories) were described with a Cox model to determine prevalence ratios for each category. We compared adjusted and unadjusted ratios to quantify the contribution of occupational exposures. RESULTS: The prevalence of low-back pain for >30 days was 13.6%. The prevalence of low-back pain adjusted for age was significantly higher for blue-collar workers and clerks than for managers. The number of socioeconomic disparities observed was significantly reduced when biomechanical strains were taken into account; adjusting for psychosocial factors had little impact. CONCLUSION: In this population, occupational exposures--especially biomechanical strains--played an important role in occupational class disparities for persistent or recurrent low-back pain

    [Personal and occupational factors associated with low-back pain in a general working population in France].: low-back pain in working population in France

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    International audienceThis study showed strong associations between occupational exposures and persistent/recurrent low-back pain in a general working population in France. Targeting these exposures in prevention programs could be useful

    Level of education and back pain in France: the role of demographic, lifestyle and physical work factors.

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    International audiencePURPOSE: To investigate the pathways from level of education to low back pain (LBP) in the adult population, especially concerning the role of physical working constraints, and personal factors (overweight, tobacco consumption, and tallness). METHODS: The study population consisted of 15,534 subjects from the National Health Survey, with data on LBP, level of education, personal factors, and physical working constraints. Logistic models for LBP (pain more than 30 days during the previous 12 months) were compared in order to check the consistency of the data with specific causal pathways. RESULTS: Low back pain was strongly associated with level of education. This association was almost completely explained if present or past exposure to tiring work postures and handling of heavy loads were taken into account. For men, the OR for "no diploma", adjusted only for age, was 1.75; it was 1.02 after additional adjustment on physical work factors. Personal factors played also a role, especially overweight for women. Among them, the OR associated with a body mass index = 27 or more was 1.58 after adjustment on all the other factors. CONCLUSIONS: In this national population the main pathways from education to LBP were through occupational exposure and lifestyle factors
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