Convivencia de niños con y sin necesidades educativas especiales en el aula tradicional

Tesis (Educadora de Párvulos, Licenciada en Educación)El objetivo de este Seminario de Grado es detectar la influencia que tiene la integración de niños con Necesidades Educativas Especiales en la convivencia en el aula con alumnos sin Necesidades Educativas Especiales en dos establecimientos públicos y de un nivel socioeconómico similar. La metodología utilizada en la tesis es de tipo cualitativa, ya que se procura lograr una descripción holística de la realidad estudiada mediante un análisis exhaustivo de la convivencia e integración que existe entre niños sin necesidades especiales con los que si poseen alguna necesidad educativa especial. Además, se enfatizan tanto los procesos de la investigación como los resultados finales de ésta. Para esto, se acopiará información mediante una entrevista y observación de campo no participante, las cuales se llevarán a cabo de forma presencial en dos establecimientos educacionales, para posteriormente comparar y analizar los comportamientos visualizados en los dos instrumentos aplicados. Los resultados esperados principalmente son; tener una visión acerca de lo observado en la convivencia de los párvulos que tienen necesidades educativas especiales con los que no poseen alguna necesidad dentro del aula regular, a través de las deducciones y la información obtenida en esta investigación, se busca sensibilizar y crear conciencia a la sociedad, ya que el tema de la educación es una temática vigente pero no hay muchas investigaciones ni regularizaciones para que la integración de los niños con NEE en el aula regular sea totalmente aprovechada por el alumno. Al realizar esta tesis, se busca tener un conocimiento profundo sobre como los párvulos están siendo integrados y qué es lo que los docentes requieren y lo que les falta para poder lograr esta integración en pleno equilibrio junto a los otros niños, entregando las mejores herramientas.The purpose of this seminary is to detect the influence of integrating children with special education needs in the same classroom as kids who have no special needs, in two public schools of a similar socio-economic level. The method employed is completely qualitative, which intends to achieve a holistic description, in other words, analyze thoroughly every detail about the classroom coexistence of kids with special needs and those without. The investigation process and the results of this are explained in great detail. To accomplish the aforementioned, the evaluation will consist of an interview and non-participant observation which will be conducted at both schools previously named, to then analyze de behavior observed with both applied methods. The expected outcome is to have a clearer vision of how those children with special needs behave and respond to the different situations, compared to those who do not have special needs. With the results and information obtained the plan is to inform and spread awareness of the subject at hand. Education for children with special needs is a recurring subject in our society but no conclusive studies have been conducted, and no formal legislation exits to help them fully be submerged in a learning environment. Throughout this thesis, the objective is to gain profound knowledge about how these kids are being integrated, why it works and why it does not, and also what teachers need to be able to help in this process, and help them

A Sustainable Approach for Extracting Non-Extractable Phenolic Compounds from Mangosteen Peel Using Ultrasound-Assisted Extraction and Natural Deep Eutectic Solvents

Mangosteen (Garcinia mangostana L.) peel is a potential source of phenolic compounds with beneficial properties. Natural deep eutectic solvents (NaDES) have been considered an environmentally friendly and cheap alternative to conventional organic solvents. In this work, a green extraction methodology was developed using ultrasound-assisted extraction (UAE) and NaDES for the extraction of antioxidant non-extractable polyphenols (NEPs) from mangosteen peel. To select the best NaDES to extract NEPs from mangosteen peel, seven NaDES were studied. Antioxidant capacity and total phenolic and proanthocyanidin contents were determined for the extracts. The molecular weights for the NEPs present in those extracts were evaluated by size exclusion chromatography. Experimental results showed that choline chloride&-lactic acid (1:2) was the NaDES allowing the highest antioxidant proanthocyanidin content in the extracts. A Box&-Behnken experimental design was employed to optimize the main parameters in UAE with NaDES: water percentage, ultrasound amplitude, and extraction time. The optimal extraction conditions were 18.8% (v/v) water, 60% ultrasound amplitude, and 15 min as the extraction time. In addition, the cytotoxicity of the NEP extracts obtained under optimal extraction conditions was evaluated. Results indicated for the first time that the use of NaDES in combination with UAE could be a sustainable alternative for the extraction of antioxidant NEPs from mangosteen peel for important applications in the food, pharmaceutical, agrochemical, and cosmetic fields, as the extracts presented low cytotoxicity

Liver tumors in dogs : treatment strategies for canine hepatocellular carcinoma

PòsterJun

Primary Small Cell Carcinoma of the Lung Presenting with Breast and Skin Metastases

Cutaneous metastases originating from an internal cancer are relatively uncommon in clinical practice, and metastatic lesions to the breast are rarer than those to the skin. Skin metastases of lung cancer, which may be the first sign of the disease, usually indicate progressive disease and a poor prognosis. We describe a 47-year-old male who presented with recurring masses in the lumbar region bilaterally and the right breast. Immunohistochemical findings and radiological imaging suggested lung cancer. This is the first reported case of small cell lung cancer metastasizing to two separate, uncommon sites, the skin and breast

Guía de recursos de extracción terminológica para el traductor especializado

Inmersos en un mundo donde la traducción automática ha llegado para formar una parte indispensable del flujo de trabajo del traductor, nunca ha sido más importante la necesidad de saber gestionar correctamente las herramientas terminológicas de que disponemos, con el fin de abarcar una traducción del mejor modo posible. Este trabajo analizará los distintos recursos que el traductor especializado tiene a su disposición para hacer gestiones terminológicas, y desglosará su importancia en un ámbito de traducción especializada, tomando como ejemplo de validez la creación de un glosario bilingüe con 37 términos procedentes de normativa europea en materia medioambiental.In a world where machine translation has become an essential part of the translator's workflow, the need to know how to manage correctly the terminology tools at our disposal has never been more important in order to ensure a translation in the best possible way. This work will analyze the different resources available to the specialized translator for terminological extractions, and break down its importance in a specialized translation field, taking as an example the creation of a bilingual glossary with 36 terms from European environmental legislation

Effects of Low-Load Blood Flow Restriction Resistance Training on Muscle Strength and Hypertrophy Compared with Traditional Resistance Training in Healthy Adults Older Than 60 Years: Systematic Review and Meta-Analysis

Background: There is clinical interest in determining the effects of low-load blood flow restriction (LL-BFR) resistance training on muscle strength and hypertrophy compared with traditional high- and low-load (HL and LL) resistance training in healthy older adults and the influence of LL-BFR training cuff-pressure on these outcomes. Methods: A search was performed on the MEDLINE, PEDro, CINHAL, Web of Science, Science Direct, Scopus, and CENTRAL databases. Results: The analysis included 14 studies. HL resistance training produces a small increase in muscle strength (eight studies; SMD, −0.23 [−0.41; −0.05]) but not in muscle hypertrophy (six studies; (SMD, 0.08 [−0.22; 0.38]) when compared with LL-BFR resistance training. Compared with traditional LL resistance training, LL-BFR resistance training produces small moderate increases in muscle strength (seven studies; SMD, 0.44 [0.28; 0.60]) and hypertrophy (two studies; SMD, 0.51 [0.06; 0.96]). There were greater improvements in muscle strength when higher cuff pressures were applied versus traditional LL resistance training but not versus HL resistance training. Conclusions: LL-BFR resistance training results in lower muscle strength gains than HL resistance training and greater than traditional LL resistance training in healthy adults older than 60 years. LL-BFR resistance training promotes a similar muscle hypertrophy to HL resistance training but is greater than that of traditional LL resistance training. Applying cuff pressures above the limb occlusion pressure could enhance the increases in muscle strength compared with traditional LL resistance training.Sección Deptal. de Radiología, Rehabilitación y Fisioterapia (Enfermería)Fac. de Enfermería, Fisioterapia y PodologíaTRUEpu

Performance of prognostic index in severe Clostridium difficile-associated infection. Retrospective analysis in a university hospital

Indexación: ScieloIntroducción: Por consenso, la infección asociada a Clostridium difficile (IACD) grave es aquella que resulta en hospitalización en unidad de cuidados intensivos, colectomía o muerte dentro de 30 días. Múltiples índices pronósticos (IP) intentan predecir estos eventos adversos. Objetivo: evaluar el rendimiento de cuatro IP en la predicción de IACD grave. Metodología: pacientes hospitalizados ≥ 18 años con IACD fueron evaluados retrospectivamente. Se excluyeron pacientes con infección recurrente o cáncer hematológico. Se evaluaron cuatro IP: UPMC versión 1, Calgary versión 1, Hines VA y Calgary versión 2. Resultados: Siete de 81 pacientes (8,1%) presentaron una IACD grave. El valor predictor positivo (VPP) y valor predictor negativo (VPN) de los IP varió entre 20-75% y 91,3-95,7%, respectivamente. Sólo el índice de Hines VA tuvo un índice Kappa satisfactorio (0,74;IC 95% 0,46-1) con un VPP de 75% y un VPN de 95,7%. Sin embargo, por las variables incluidas en este IP, sólo pudo ser calculado en 32,6% de los pacientes. Conclusión: El índice de Hines VA presenta el mejor valor predictor y concordancia para descartar una IACD grave. Como otros IP, tiene la limitación de incluir variables difícilmente evaluables en todos los pacientes y tiende a sobreestimar un curso desfavorable.Introduction: By consensus severe, Clostridium difficile-associated infection (CDAI) is one that results in hospitalization in ICU, colectomy or death within 30 days. Multiple prognostic indices (IP) attempt to predict these adverse events. Objective: To evaluate the performance of 4 PI in predicting severe CDI. Methods: Hospitalized patients ≥ 18 years old with ICD were retrospectively evaluated. Patients with recurrent infection or hematological cancer were excluded. Four PI were evaluated: UPMC version 1, Calgary version 1, Hines VA and Calgary version 2. Results: Seven of 81 patients (8.1%) met the definition of severe CDI. Positive predicted value (PPV) and negative predicted value (NPV) of PI ranged from 20-75% and 91.3-95.7%, respectively. Only Hines VA index had a satisfactory Kappa index (0.74; 95% CI 0.41-1) with a PPV of 75% and NPV of 95,7%. However, because of the variables included, this PI could be calculated only in 32.6% of patients. Conclusion: Hines VA index has the best predicted value and agreement to rule out a severe CDI. Like others PI it has the limitation of including difficult variables to assess in all patients and tends to overestimate an unfavorable course.http://www.scielo.cl/pdf/rci/v31n6/art03.pd

SMEPP: A Secure Middleware For Embedded P2P

Abstract: The increasing presence of embedded devices with internet access capabilities constitutes a new challenge in software development. These devices are now cooperating in a distributed manner towards what has been called as "Internet of Things". In this new scenario the client-server model is sometimes not adequate and dynamic ad-hoc networks are more common than before. However, security poses as a hard issue as these systems are extremely vulnerable. In this paper, we introduce SMEPP project, which aims at developing a middleware designed for P2P systems with a special focus on embedded devices and security. SMEPP is designed to be deployed in a wide range of devices. It tries to ease the development of applications hiding platforms details and other aspects such as scalability, adaptability and interoperability. A full implementation of this middleware is already available that incorporates security features specially designed for low-resource devices. Moreover, we describe two business applications being developed using this middleware in the context of "Digital Home" and "Environmental Monitoring in Industrial Environments"

Cadmium, Smoking, and Human Blood DNA Methylation Profiles in Adults from the Strong Heart Study.

The epigenetic effects of individual environmental toxicants in tobacco remain largely unexplored. Cadmium (Cd) has been associated with smoking-related health effects, and its concentration in tobacco smoke is higher in comparison with other metals. We studied the association of Cd and smoking exposures with human blood DNA methylation (DNAm) profiles. We also evaluated the implication of findings to relevant methylation pathways and the potential contribution of Cd exposure from smoking to explain the association between smoking and site-specific DNAm. We conducted an epigenome-wide association study of urine Cd and self-reported smoking (current and former vs. never, and cumulative smoking dose) with blood DNAm in 790,026 CpGs (methylation sites) measured with the Illumina Infinium Human MethylationEPIC (Illumina Inc.) platform in 2,325 adults 45-74 years of age who participated in the Strong Heart Study in 1989-1991. In a mediation analysis, we estimated the amount of change in DNAm associated with smoking that can be independently attributed to increases in urine Cd concentrations from smoking. We also conducted enrichment analyses and in silico protein-protein interaction networks to explore the biological relevance of the findings. At a false discovery rate (FDR)-corrected level of 0.05, we found 6 differentially methylated positions (DMPs) for Cd; 288 and 17, respectively, for current and former smoking status; and 77 for cigarette pack-years. Enrichment analyses of these DMPs displayed enrichment of 58 and 6 Gene Ontology and Kyoto Encyclopedia of Genes and Genomes gene sets, respectively, including biological pathways for cancer and cardiovascular disease. In in silico protein-to-protein networks, we observed key proteins in DNAm pathways directly and indirectly connected to Cd- and smoking-DMPs. Among DMPs that were significant for both Cd and current smoking (annotated to PRSS23, AHRR, F2RL3, RARA, and 2q37.1), we found statistically significant contributions of Cd to smoking-related DNAm. Beyond replicating well-known smoking epigenetic signatures, we found novel DMPs related to smoking. Moreover, increases in smoking-related Cd exposure were associated with differential DNAm. Our integrative analysis supports a biological link for Cd and smoking-associated health effects, including the possibility that Cd is partly responsible for smoking toxicity through epigenetic changes. https://doi.org/10.1289/EHP6345.This work was supported by grants by the National Heart, Lung, and Blood Institute (NHLBI) (under contract numbers 75N92019D00027, 75N92019D00028, 75N92019D00029, & 75N92019D00030) and previous grants (R01HL090863, R01HL109315, R01HL109301, R01HL109284, R01HL109282, and R01HL109319 and cooperative agreements U01HL41642, U01HL41652, U01HL41654, U01HL65520, and U01HL65521), by the National Institute of Health Sciences (R01ES021367, R01ES025216, P42ES010349, P30ES009089), by the Spanish Funds for Research In Health Sciences, Carlos III Health Institute, co-funded by European Regional Development Fund (CP12/03080 and PI15/00071), by Chilean CONICYT/FONDECYT-POSTDOCTORADO Nº3180486 (A.L.R.-C) and a fellowship from “La Caixa” Foundation (ID 100010434). The fellowship code is “LCF/BQ/DR19/11740016.”S