Comedias sueltas del Museo Nacional del Teatro

Encuadernado con otras obras bajo el título: Cada uno para sí ... [y otras obras]Copia digital. Madrid : Ministerio de Cultura. Subdirección General de Coordinación Bibliotecaria, 2009Texto a dos col

Interseismic coupling and seismic potential along the Central Andes subduction zone

We use about two decades of geodetic measurements to characterize interseismic strain build up along the Central Andes subduction zone from Lima, Peru, to Antofagasta, Chile. These measurements are modeled assuming a 3-plate model (Nazca, Andean sliver and South America Craton) and spatially varying interseismic coupling (ISC) on the Nazca megathrust interface. We also determine slip models of the 1996 M_w = 7.7 Nazca, the 2001 M_w = 8.4 Arequipa, the 2007 M_w = 8.0 Pisco and the M_w = 7.7 Tocopilla earthquakes. We find that the data require a highly heterogeneous ISC pattern and that, overall, areas with large seismic slip coincide with areas which remain locked in the interseismic period (with high ISC). Offshore Lima where the ISC is high, a M_w∼8.6–8.8 earthquake occurred in 1746. This area ruptured again in a sequence of four M_w∼8.0 earthquakes in 1940, 1966, 1974 and 2007 but these events released only a small fraction of the elastic strain which has built up since 1746 so that enough elastic strain might be available there to generate a M_w > 8.5 earthquake. The region where the Nazca ridge subducts appears to be mostly creeping aseismically in the interseismic period (low ISC) and seems to act as a permanent barrier as no large earthquake ruptured through it in the last 500 years. In southern Peru, ISC is relatively high and the deficit of moment accumulated since the M_w∼8.8 earthquake of 1868 is equivalent to a magnitude M_w∼8.4 earthquake. Two asperities separated by a subtle aseismic creeping patch are revealed there. This aseismic patch may arrest some rupture as happened during the 2001 Arequipa earthquake, but the larger earthquakes of 1604 and 1868 were able to rupture through it. In northern Chile, ISC is very high and the rupture of the 2007 Tocopilla earthquake has released only 4% of the elastic strain that has accumulated since 1877. The deficit of moment which has accumulated there is equivalent to a magnitude M_w∼8.7 earthquake. This study thus provides elements to assess the location, size and magnitude of future large megathurst earthquakes in the Central Andes subduction zone. Caveats of this study are that interseismic strain of the forearc is assumed time invariant and entirely elastic. Also a major source of uncertainty is due to fact that the available data place very little constraints on interseismic coupling at shallow depth near the trench, except offshore Lima where sea bottom geodetic measurements have been collected suggesting strong coupling

Anti-tumour necrosis factor discontinuation in inflammatory bowel disease patients in remission: study protocol of a prospective, multicentre, randomized clinical trial

Background: Patients with inflammatory bowel disease who achieve remission with anti-tumour necrosis factor (anti-TNF) drugs may have treatment withdrawn due to safety concerns and cost considerations, but there is a lack of prospective, controlled data investigating this strategy. The primary study aim is to compare the rates of clinical remission at 1?year in patients who discontinue anti-TNF treatment versus those who continue treatment. Methods: This is an ongoing, prospective, double-blind, multicentre, randomized, placebo-controlled study in patients with Crohn?s disease or ulcerative colitis who have achieved clinical remission for ?6?months with an anti-TNF treatment and an immunosuppressant. Patients are being randomized 1:1 to discontinue anti-TNF therapy or continue therapy. Randomization stratifies patients by the type of inflammatory bowel disease and drug (infliximab versus adalimumab) at study inclusion. The primary endpoint of the study is sustained clinical remission at 1?year. Other endpoints include endoscopic and radiological activity, patient-reported outcomes (quality of life, work productivity), safety and predictive factors for relapse. The required sample size is 194 patients. In addition to the main analysis (discontinuation versus continuation), subanalyses will include stratification by type of inflammatory bowel disease, phenotype and previous treatment. Biological samples will be obtained to identify factors predictive of relapse after treatment withdrawal. Results: Enrolment began in 2016, and the study is expected to end in 2020. Conclusions: This study will contribute prospective, controlled data on outcomes and predictors of relapse in patients with inflammatory bowel disease after withdrawal of anti-TNF agents following achievement of clinical remission. Clinical trial reference number: EudraCT 2015-001410-1

4to. Congreso Internacional de Ciencia, Tecnología e Innovación para la Sociedad. Memoria académica

Este volumen acoge la memoria académica de la Cuarta edición del Congreso Internacional de Ciencia, Tecnología e Innovación para la Sociedad, CITIS 2017, desarrollado entre el 29 de noviembre y el 1 de diciembre de 2017 y organizado por la Universidad Politécnica Salesiana (UPS) en su sede de Guayaquil. El Congreso ofreció un espacio para la presentación, difusión e intercambio de importantes investigaciones nacionales e internacionales ante la comunidad universitaria que se dio cita en el encuentro. El uso de herramientas tecnológicas para la gestión de los trabajos de investigación como la plataforma Open Conference Systems y la web de presentación del Congreso http://citis.blog.ups.edu.ec/, hicieron de CITIS 2017 un verdadero referente entre los congresos que se desarrollaron en el país. La preocupación de nuestra Universidad, de presentar espacios que ayuden a generar nuevos y mejores cambios en la dimensión humana y social de nuestro entorno, hace que se persiga en cada edición del evento la presentación de trabajos con calidad creciente en cuanto a su producción científica. Quienes estuvimos al frente de la organización, dejamos plasmado en estas memorias académicas el intenso y prolífico trabajo de los días de realización del Congreso Internacional de Ciencia, Tecnología e Innovación para la Sociedad al alcance de todos y todas

Novel orthogonal multi-sequences for an efficient jamming on the UMTS signal

In this paper, a novel and efficient scheme for jamming the Universal Mobile Telecommunications System (UMTS) signal without the assistance from the base station or operator is proposed and evaluated. The scheme is based on new orthogonal multi-sequences developed in this paper. These sequences are specially designed to interfere all the Orthogonal Variable Spread Factor (OVSF) codes that are used in the UMTS transmission and thus, any signal spread by these multi-sequences will interfere all the transmitted data channels at the same time. A power gain of about 7 dB is obtained with respect to the traditional jamming method based on high power wide-band noise injection can be obtained when no channel is used and 10.4 dB in a more realistic scenario with multipath Rayleigh channel