Anniversary of a beekeeper’s discovery of thelytoky in Cape honey bees

Significance: The laying workers of the Cape honey bee continue to negatively affect the South African beekeeping industry, with more losses suffered in the northern regions of the country. The reproductive parasites enter susceptible host colonies, activate their ovaries, and lay diploid eggs, leading to colony dwindling and collapse. Diploidy in eggs produced by unmated laying workers arises from thelytokous parthenogenesis, first discovered in honey bees by a hobbyist beekeeper. We examine the consequences of thelytokous parthenogenesis and outline what is being done to understand and limit the spread of the laying workers of the Cape honey bee

Hadamard States and Adiabatic Vacua

Reversing a slight detrimental effect of the mailer related to TeXabilityComment: 10pages, LaTeX (RevTeX-preprint style

BEACON:A Summary Framework to Overcome Potential Reimbursement Hurdles

Objective To provide a framework for addressing payers' criteria during the development of pharmaceuticals. Methods A conceptual framework was presented to an international health economic expert panel for discussion. A structured literature search (from 2010 to May 2015), using the following databases in Ovid: Medline((R)) and Medline((R)) In-Process (PubMed), Embase (Ovid), EconLit (EBSCOhost) and the National Health Service Economic Evaluation Database (NHS EED), and a 'grey literature' search, were conducted to identify existing criteria from the payer perspective. The criteria assessed by existing frameworks and guidelines were collated; the most commonly reported criteria were considered for inclusion in the framework. A mnemonic was conceived as a memory aide to summarise these criteria. Results Overall, 41 publications were identified as potentially relevant to the objective. Following further screening, 26 were excluded upon full-text review on the basis of no framework presented (n = 13), redundancy (n = 11) or abstract only (n = 2). Frameworks that captured criteria developed for or utilised by the pharmaceutical industry (n = 5) and reimbursement guidance (n = 10) were reviewed. The most commonly identified criteria-unmet need/patient burden, safety, efficacy, quality-of-life outcomes, environment, evidence quality, budget impact and comparator-were incorporated into the summary framework. For ease of communication, the following mnemonic was developed: BEACON (Burden/target population, Environment, Affordability/value, Comparator, Outcomes, Number of studies/quality of evidence). Conclusions The BEACON framework aims to capture the 'essence' of payer requirements by addressing the most commonly described criteria requested by payers regarding the introduction of a new pharmaceutical

The territorial invasion of Apis florea in Africa

No abstract available.http://reference.sabinet.co.za/sa_epublication/entohttp://www.entsocsa.co.za/Publications.htm2016-12-31hb201

Conformal Transformations of the Wigner Function and Solutions of the Quantum Corrected Vlasov Equation

We study conformal properties of the quantum kinetic equations in curved spacetime. A transformation law for the covariant Wigner function under conformal transformations of a spacetime is derived by using the formalism of tangent bundles. The conformal invariance of the quantum corrected Vlasov equation is proven. This provides a basis for generating new solutions of the quantum kinetic equations in the presence of gravitational and other external fields. We use our method to find explicit quantum corrections to the class of locally isotropic distributions, to which equilibrium distributions belong. We show that the quantum corrected stress--energy tensor for such distributions has, in general, a non--equilibrium structure. Local thermal equilibrium is possible in quantum systems only if an underlying spacetime is conformally static (not stationary). Possible applications of our results are discussed.Comment: 30 page

The exceptional attachment ability of the ectoparasitic bee louse Braula coeca (Diptera, Braulidae) on the honeybee

Bee lice (Braulidae) are small parasitic flies, which are adapted to live on their bee host. As such, the wingless Braula coeca is a parasite of the common honey bee Apis mellifera and it is well adapted to attach to its hairy surface. The attachment system of B. coeca provides a secure grip on the fine setae of the bee. This is crucial for the parasite survival, as detachment from the host is fatal for the bee louse. The feet morphology of B. coeca is well adapted to the challenging bee surface, notably by strongly broadened claws, which are split into a high number of comb-like teeth, perfectly matching the diameter of the bee hairs. Based on microscopy observations, both the morphology and material composition of the tarsi of B. coeca are characterized in detail. Using high-speed video analysis, we combine the morphology data on the attachment system with a behavioural context. Furthermore, we directly measured the attachment forces generated by the bee lice in contact with the host. In particular, the claws are involved in attachment to the host, as the interstices between the teeth-like spines allow for the collection of several hairs and generate strong friction, when the hairs slip to the narrow gap between the spines. The overall morphology of the tarsus produces strong attachment, with average safety factors (force per body weight) around 1130, and stabilizes the tarsal chain with lateral stoppers against overflexion, but also allows for the fast detachment by the tarsal chain torsion.Deutsche Forschungsgemeinschaft; Human Frontier Science Program and the National Research Foundation.https://onlinelibrary.wiley.com/journal/13653032hj2021Zoology and Entomolog

Compounds extracted from heads of African stingless bees (Hypotrigona species) as a prospective taxonomic tool

Stingless bees are important pollinators of plants, and also producers of honey. Species within the African stingless bee genus Hypotrigona are difficult to differentiate due to morphological similarities. Chemical profiles of whole head extracts from workers of three Hypotrigona species: H. gribodoi, H. araujoi and H. ruspolii were studied by gas chromatography–mass spectrometry. A total of 50 components belonging to six chemical classes: hydrocarbons, aldehydes, alcohols, terpenoids, steroids and fatty acids were identified. Twenty-nine compounds were found in H. araujoi, 26 in H. gribodoi and 33 in H. ruspolii head extracts. Hydrocarbons, alcohols and fatty acids were the major classes, whilst steroids and terpenoids were minor. Aldehydes were found only in H. ruspolii while terpenoids were only present in extracts of H. gribodoi and H. araujoi. Eight chemical compounds were specific to H. araujoi, six to H. gribodoi and nine to H. ruspolii, showing both qualitative and quantitative differences. Workers were successfully grouped into their respective species using their chemical profiles. This study shows that head extracts can be used as a reliable taxonomic tool for identifying and differentiating Hypotrigona species.The European Union (EU) (Grant Contract No. DCI-FOOD/2013/313-659: African Reference Laboratory (with satellite stations) for the Management of Pollination Bee Diseases and Pests for Food Security); the South African National Research Foundation (NRF) Research Career Advancement Fellowship (Grant no: 91419) to AAY; NRF Incentive Funding for Rated Researchers to CWWP and AAY; UK Aid from the UK Government; Swedish International Development Cooperation Agency (Sida); the Swiss Agency for Development and Cooperation (SDC) and the Kenyan Government. The first author was supported by a German Academic Exchange Service (DAAD) In-Region Postgraduate Scholarship.https://link.springer.com/journal/492019-04-01hj2018Zoology and Entomolog

GRAB: A Dataset of Whole-Body Human Grasping of Objects

Training computers to understand, model, and synthesize human grasping requires a rich dataset containing complex 3D object shapes, detailed contact information, hand pose and shape, and the 3D body motion over time. While "grasping" is commonly thought of as a single hand stably lifting an object, we capture the motion of the entire body and adopt the generalized notion of "whole-body grasps". Thus, we collect a new dataset, called GRAB (GRasping Actions with Bodies), of whole-body grasps, containing full 3D shape and pose sequences of 10 subjects interacting with 51 everyday objects of varying shape and size. Given MoCap markers, we fit the full 3D body shape and pose, including the articulated face and hands, as well as the 3D object pose. This gives detailed 3D meshes over time, from which we compute contact between the body and object. This is a unique dataset, that goes well beyond existing ones for modeling and understanding how humans grasp and manipulate objects, how their full body is involved, and how interaction varies with the task. We illustrate the practical value of GRAB with an example application; we train GrabNet, a conditional generative network, to predict 3D hand grasps for unseen 3D object shapes. The dataset and code are available for research purposes at https://grab.is.tue.mpg.de.Comment: ECCV 202

An improved method for measuring muon energy using the truncated mean of dE/dx

The measurement of muon energy is critical for many analyses in large Cherenkov detectors, particularly those that involve separating extraterrestrial neutrinos from the atmospheric neutrino background. Muon energy has traditionally been determined by measuring the specific energy loss (dE/dx) along the muon's path and relating the dE/dx to the muon energy. Because high-energy muons (E_mu > 1 TeV) lose energy randomly, the spread in dE/dx values is quite large, leading to a typical energy resolution of 0.29 in log10(E_mu) for a muon observed over a 1 km path length in the IceCube detector. In this paper, we present an improved method that uses a truncated mean and other techniques to determine the muon energy. The muon track is divided into separate segments with individual dE/dx values. The elimination of segments with the highest dE/dx results in an overall dE/dx that is more closely correlated to the muon energy. This method results in an energy resolution of 0.22 in log10(E_mu), which gives a 26% improvement. This technique is applicable to any large water or ice detector and potentially to large scintillator or liquid argon detectors.Comment: 12 pages, 16 figure