39 research outputs found
Pratiques de supervision d'équipe utilisées par les supérieurs immédiats : validation d'un questionnaire
Mémoire numérisé par la Division de la gestion de documents et des archives de l'Université de Montréal
Étude archéométallurgique du dépôt de grands bronzes du sanctuaire gallo-romain du Vieil-Evreux (Eure)
Cet article présente les résultats d’une étude archéométallurgique réalisée sur un important dépôt de bronze découvert en 1840 sur le site du sanctuaire gallo-romain du Vieil-Evreux. De récentes découvertes de fragments au sein du sanctuaire, ainsi qu’une relecture des données d’archives, ont amené à redéfinir la nature et le contexte de ce dépôt.This article reports the results of an archeometallurgical study carried out on an important bronze hoard discovered in 1840 on the gallo-roman sanctuary of Vieil-Evreux. Recent excavations provided other fragments, and a study of the archive data, led to redefine the nature and context of this hoard. The work was conducted by the C2RMF, in collaboration with the CEA Le Ripault and the MADE, and the analytical procedure involved the use of multiple techniques such as radiography, tomography, endoscopy, or the determination of elemental composition by ICP-AES of the various pieces of bronze. Two main results were obtained so far. The first is directly related to the understanding of the Vieil-Evreux site by determining the minimal number of statues in the bronze hoard and more accurate the identification of their iconography. The second, more general, is to integrate and compare the data in the research program concerning the study of the manufacturing techniques of the Greek and Roman large bronze statues (including the study of the lost wax process and the welding process)
Mise en oeuvre d’une gouvernance collaborative fondée sur l’engagement communautaire pour une gestion de crise sanitaire résiliente : une étude des plans d’action communautaires de lutte à la COVID-19
Les expériences passées lors des épidémies d’Ebola, de SARS ou Zika ont montré que les communautés engagées et impliquées dans la construction des solutions coopéreraient davantage pour endiguer les crises. L’Organisation mondiale de la santé (OMS), le Fonds des Nations Unies pour l’enfance (UNICEF), la Fédération internationale des Sociétés de la Croix-Rouge et du Croissant-Rouge (FICR) et la communauté scientifique recommandent ainsi l’intégration des communautés dans la prévention et le contrôle de la pandémie de COVID-19. Le présent rapport recourt à l’approche whole-of-society qui reconnaît l’apport essentiel des groupes citoyens, des organismes communautaires et des réseaux inter-organisationnels à la réponse aux crises ainsi que l’approche de la gestion de crise en réseau qui appelle à une gouvernance collaborative et à différents niveaux de résilience
Métallurgie : orientations pour le développement du secteur : document de consultation /
La couv. porte en outre: La formation professionnelle au secondaireBibliogr.: p. 93-9
Mantes-la-Jolie (Yvelines), 74 rue de la Porte aux Saints : rapport de fouille archéologique
Mantes-la-Jolie (Yvelines), 74 rue de la Porte aux Saints : rapport de fouille archéologique
Mantes-la-Jolie (Yvelines), 74 rue de la Porte aux Saints : rapport de fouille archéologique
A discriminant analysis of plasma metabolomics for the assessment of metabolic responsiveness to red raspberry consumption
BackgroundMany studies show that the intake of raspberries is beneficial to immune-metabolic health, but the responses of individuals are heterogeneous and not fully understood.MethodsIn a two-arm parallel-group, randomized, controlled trial, immune-metabolic outcomes and plasma metabolite levels were analyzed before and after an 8-week red raspberry consumption. Based on partial least squares discriminant analysis (PLS-DA) on plasma xenobiotic levels, adherence to the intervention was first evaluated. A second PLS-DA followed by hierarchical clustering was used to classify individuals into response subgroups. Clinical immune and metabolic outcomes, including insulin resistance (HOMA-IR) and sensitivity (Matsuda, QUICKI) indices, during the intervention were assessed and compared between response subgroups.ResultsTwo subgroups of participants, type 1 responders (n = 17) and type 2 responders (n = 5), were identified based on plasma metabolite levels measured during the intervention. Type 1 responders showed neutral to negative effects on immune-metabolic clinical parameters after raspberry consumption, and type 2 responders showed positive effects on the same parameters. Changes in waist circumference, waist-to-hip ratio, fasting plasma apolipoprotein B, C-reactive protein and insulin levels as well as Matsuda, HOMA-IR and QUICKI were significantly different between the two response subgroups. A deleterious effect of two carotenoid metabolites was also observed in type 1 responders but these variables were significantly associated with beneficial changes in the QUICKI index and in fasting insulin levels in type 2 responders. Increased 3-ureidopropionate levels were associated with a decrease in the Matsuda index in type 2 responders, suggesting that this metabolite is associated with a decrease in insulin sensitivity for those subjects, whereas the opposite was observed for type 1 responders.ConclusionThe beneficial effects associated with red raspberry consumption are subject to inter-individual variability. Metabolomics-based clustering appears to be an effective way to assess adherence to a nutritional intervention and to classify individuals according to their immune-metabolic responsiveness to the intervention. This approach may be replicated in future studies to provide a better understanding of how interindividual variability impacts the effects of nutritional interventions on immune-metabolic health