Haplotype affinities resolve a major component of goat (<i>Capra hircus</i>) MtDNA D-loop diversity and reveal specific features of the Sardinian stock

Goat mtDNA haplogroup A is a poorly resolved lineage absorbing most of the overall diversity and is found in locations as distant as Eastern Asia and Southern Africa. Its phylogenetic dissection would cast light on an important portion of the spread of goat breeding. The aims of this work were 1) to provide an operational definition of meaningful mtDNA units within haplogroup A, 2) to investigate the mechanisms underlying the maintenance of diversity by considering the modes of selection operated by breeders and 3) to identify the peculiarities of Sardinian mtDNA types. We sequenced the mtDNA D-loop in a large sample of animals (1,591) which represents a non-trivial quota of the entire goat population of Sardinia. We found that Sardinia mirrors a large quota of mtDNA diversity of Western Eurasia in the number of variable sites, their mutational pattern and allele frequency. By using Bayesian analysis, a distance-based tree and a network analysis, we recognized demographically coherent groups of sequences identified by particular subsets of the variable positions. The results showed that this assignment system could be reproduced in other studies, capturing the greatest part of haplotype diversity. We identified haplotype groups overrepresented in Sardinian goats as a result of founder effects. We found that breeders maintain diversity of matrilines most likely through equalization of the reproductive potential. Moreover, the relevant amount of inter-farm mtDNA diversity found does not increase proportionally with distance. Our results illustrate the effects of breeding practices on the composition of maternal gene pool and identify mtDNA types that may be considered in projects aimed at retrieving the maternal component of the oldest breeds of Sardinia.</br

Solar radiation effects on the Sardinia Radio Telescope performances

The Sardinia Radio Telescope, a 64-metre diameter fully steerable radio telescope operated by INAF, will be upgraded in order to extend its current operating frequency range 0.3-26.5 GHz up to 116 GHz, thanks to a National Operational Program (PON) funding assigned to INAF by the Italian Ministry of University and Research. The PON project is organized in nine Work Packages, one of which is dedicated to the accomplishment of a sophisticated metrology system designed to monitor the cause of the pointing errors and the reflector surface deformations. The entire antenna structure will therefore be equipped with a network of sensors, like thermal sensors, inclinometers, accelerometers, collimators, anemometers, strain gauges and others, to study environmental stresses and how they affect the SRT performances. This work is devoted to the investigation of the thermal stress effects produced by solar radiation. In particular, two analyses are carried out to confirm the relevance of a thorough temperature monitoring system, both conducted using Finite Element Analysis. First, a possible approach for the simulation of realistic thermal scenarios due to insolation is proposed and the effects on the pointing accuracy are analysed. Second, a feasible method to study the impacts that a differential heating of the Back Up Structure (BUS) produces on the radio telescope main reflector surface is presented. Finally, these effects are analysed as optical aberrations and modelled in terms of Zernike polynomials

Solar Observations with Single-Dish INAF Radio Telescopes: Continuum Imaging in the 18 - 26 GHz Range

We present a new solar radio imaging system implemented through the upgrade of the large single-dish telescopes of the Italian National Institute for Astrophysics (INAF), not originally conceived for solar observations

Status of the High-Frequency Upgrade of the Sardinia Radio Telescope

The Sardinia Radio Telescope is going through a major upgrade aimed at observing the universe at up to 116 GHz. A budget of 18.700.000 E has been awarded to the Italian National Institute of Astrophysics to acquire new state-of-the-art receivers, back-end, and high-performance computing, to develop a sophisticated metrology system and to upgrade the infrastructure and laboratories. This contribution draws the status of the whole project at eight months from the end of the funding scheme planned for August 2022

The high-frequency upgrade of the Sardinia Radio Telescope

We present the status of the Sardinia Radio Telescope (SRT) and its forthcoming update planned in the next few years. The post-process scenario of the upgraded infrastructure will allow the national and international scientific community to use the SRT for the study of the Universe at high radio frequencies (up to 116 GHz), both in single dish and in interferometric mode. A telescope like SRT, operating at high frequencies, represents a unique resource for the scientific community. The telescope will be ideal for mapping quickly and with relatively high angular resolution extended radio emissions characterized by low surface brightness. It will also be essential for spectroscopic and polarimetric studies of both Galactic and extragalactic radio sources. With the use of the interferometric technique, SRT and the other Italian antennas (Medicina and Noto) will operate within the national and international radiotelescope network, allowing astronomers to obtain images of radio sources at very high angular resolution

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

The original version of this article unfortunately contained a mistake

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

LAP: Lisbon Algae Project

En el Estuario del Tajo nos encontramos con una gran reserva natural que entra en conflicto directo con la gran actividad urbano-portuaria del Área Metropolitana de Lisboa. Como solución para éste problema, y siguiendo la tradición portuaria del lugar, la propuesta consiste en un nuevo muelle que, a diferencia de los existentes, contribuye a la regeneración del estuario. Para esto, en el nuevo muelle, ubicado en el Parque de las Naciones, se construye un centro de Investigaciones de cultivos de algas. Las propiedades de depuración y nutrición del entorno marino que nos ofrecen las algas se aprovecharán para la regeneración de la bahía y como complemento necesario para la autosuficiencia del estuario. Tres volúmenes, elevados sobre el muelle y la superficie de agua, por medio de una gran estructura metálica, permitirán la interacción directa de los laboratorios con los distintos objetos encargados del trabajo de los cultivos; a su vez, regalan una plaza para el paseo marítimo. De este modo, unas plataformas flotantes que se mueven con total libertad por la bahía hasta los cultivos, y de regreso a los laboratorios, interactúan con los laboratorios obteniendo los precultivos de los laboratorios y cediendo lo ya cultivado de regreso a los laboratorios

LAP: Lisbon Algae Project

En el Estuario del Tajo nos encontramos con una gran reserva natural que entra en conflicto directo con la gran actividad urbano-portuaria del Área Metropolitana de Lisboa. Como solución para éste problema, y siguiendo la tradición portuaria del lugar, la propuesta consiste en un nuevo muelle que, a diferencia de los existentes, contribuye a la regeneración del estuario. Para esto, en el nuevo muelle, ubicado en el Parque de las Naciones, se construye un centro de Investigaciones de cultivos de algas. Las propiedades de depuración y nutrición del entorno marino que nos ofrecen las algas se aprovecharán para la regeneración de la bahía y como complemento necesario para la autosuficiencia del estuario. Tres volúmenes, elevados sobre el muelle y la superficie de agua, por medio de una gran estructura metálica, permitirán la interacción directa de los laboratorios con los distintos objetos encargados del trabajo de los cultivos; a su vez, regalan una plaza para el paseo marítimo. De este modo, unas plataformas flotantes que se mueven con total libertad por la bahía hasta los cultivos, y de regreso a los laboratorios, interactúan con los laboratorios obteniendo los precultivos de los laboratorios y cediendo lo ya cultivado de regreso a los laboratorios