Holographic Micro Thermofield Geometries of BTZ Black Holes

We find general deformations of BTZ spacetime and identify the corresponding thermofield initial states of the dual CFT. We deform the geometry by introducing bulk fields dual to primary operators and find the back-reacted gravity solutions to the quadratic order of the deformation parameter. The dual thermofield initial states can be deformed by inserting arbitrary linear combination of operators at the mid-point of the Euclidean time evolution that appears in the construction of the thermofield initial states. The deformed geometries are dual to thermofield states without deforming the boundary Hamiltonians in the CFT side. We explicitly demonstrate that the AdS/CFT correspondence is not a linear correspondence in the sense that the linear structure of Hilbert space of the underlying CFT is realized nonlinearly in the gravity side. We also find that their Penrose diagrams are no longer a square but elongated horizontally due to deformation. These geometries describe a relaxation of generic initial perturbation of thermal system while fixing the total energy of the system. The coarse-grained entropy grows and the relaxation time scale is of order $\beta/2\pi$. We clarify that the gravity description involves coarse-graining inevitably missing some information of nonperurbative degrees.Comment: 28 pages, 7 figures, further typos corrected, reference adde

Net Neutrality and Investment Incentives

This paper analyzes the effects of net neutrality regulation on investment incentives for Internet service providers (ISPs) and content providers (CPs), and their implications for social welfare. We show that the ISP’s decision on the introduction of discrimination across content depends on a potential trade-off between network access fee and the revenue from the trade of the first-priority. Concerning the ISP’s investment incentives, we find that capacity expansion affects the sale price of the priority right under the discriminatory regime. Because the relative merit of the first priority, and thus its value, becomes relatively small for higher capacity levels, the ISP’s incentive to invest on capacity under a discriminatory network can be smaller than that under a neutral regime where such rent extraction effects do not exist. Contrary to ISPs’ claims that net neutrality regulations would have a chilling effect on their incentive to invest, we cannot dismiss the possibility of the opposite.net neutrality, investment (innovation) incentives, queuing theory, hold-up problem, two-sided markets, vertical integration

High energy-charged cell factory for heterologous protein synthesis

Overexpression of gluconeogenic phosphoenolpyruvate carboxykinase (PCK) under glycolytic conditions enables Escherichia coli to maintain a greater intracellular ATP concentration and, consequently, to up-regulate genes for amino acid and nucleotide biosynthesis. To investigate the effect of a high intracellular ATP concentration on heterologous protein synthesis, we studied the expression of a foreign gene product, enhanced green fluorescence protein (eGFP), under control of the T7 promoter in E. coli BL21(DE3) strain overexpressing PCK. This strain was able to maintain twice as much intracellular ATP and to express two times more foreign protein than the control strain. These results indicate that a high energy-charged cell can be beneficial as a protein-synthesizing cell factory. The potential uses of such a cell factory are discussed

High-performance near-infrared photodetector based on nano-layered MoSe2

In recent years, the integration of two-dimensional (2D) nanomaterials, especially transition metal chalcogendies (TMCs) and dichalcogendies (TMDCs), into electronic devices have been extensively studied owing to their exceptional physical properties such as high transparency, strong photoluminescence, and tunable bandgap depending on the number of layers. Herein, we report the optoelectronic properties of few-layered MoSe2-based backgated phototransistor used for photodetection. The photoresponsivity could be easily controlled to reach a maximum value of 238 AW–1 under near-infrared light excitation, achieving a high specific detectivity D∗ = 7.6×10** cmHz*/1W3* . Few-layered MoSe2 exhibited excellent optoelectronic properties as compared with those reported previously for multilayered 2D material-based photodetectors, indicating that our device is one of the best high-performance nanoscale near-infrared photodetector based multilayered two-dimensional materials

Analysis of Protease Activity Using Quantum Dots and Resonance Energy Transfer

This review demonstrates the detection of protease activity based on the energy transfer of quantum dots (QDs). By incorporation of varying protease substrates into designed QD probes both in fluorescence resonance energy transfer (FRET) and bioluminescence resonance energy transfer (BRET) system, proteolytic activity led to changes in the energy transfer efficiency. Especially due to the superior properties of QDs, it can be served as an excellent probe for a multiplexed and high-throughput protease assay with high sensitivity. It is anticipated that the QD-based FRET/BRET probes will have a great potential for dissecting the fundamental roles of proteases and designing potential protease inhibitors as therapeutic drugs in biology and nanomedicine

Methanogens Harboring in Rice Rhizosphere Reduce Labile Organic Carbon Compounds to Produce Methane Gas

Submerged rice paddy soils are one of the major anthropogenic sources of methane (CH4) emission to the atmosphere. Methane is the second most important greenhouse gas after carbon dioxide. Methanogens are strictly anaerobic microorganisms and CH4 is the metabolic end product of those methanogens. Methane is produced by methanogens through multi-step enzyme-mediated process. Methanogens convert labile organic carbon compounds in CH4 and application of organic matter in submerged rice field significantly increased CH4 emission from soil to the atmosphere. The rate of methanogenesis may be determined by quantifying biomarkers namely methyl coenzyme M reductase A (mcrA) gene and coenzyme M (2-mercaptoethane sulphonate) in soil. Nickel ions are present as cofactor in enzymes involved in methanogenesis. Methane emission can be mitigated by application of EDTA at suitable rate in the soil of submerged rice field