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Entrevista a René Girard sobre la globalización y la atmósfera de apocalipsis que esta crea: deseo mimético como fuente de rivalidad, caos, conflicto y violencia.pre-print4 p

Construction et réception de l’événement, XXe siècle

Pierre Laborie, directeur d’études avec Ariette Farge, directrice de recherche au CNRS Traces et temporalités de l’événement La recherche du dialogue entre historiens du XVIIIe et du XXe siècle, réunis par des préoccupations proches, a fait l’originalité de ce séminaire pendant de longues années. Elle a permis d’inventer un mode de fonctionnement spécifique, elle a orienté l’esprit avec lequel les problèmes étaient abordés, elle a favorisé les échanges entre les intervenants et la diversité d..

Construction et réception de l’événement, XXe siècle

Pierre Laborie, directeur d’études avecAriette Farge, directrice de recherche au CNRS Les traces de l’événement : usages de l’histoire et de la mémoire Autour de la problématique de l’événement et de ses traces, les axes de réflexion du séminaire ont essentiellement porté sur les problèmes liés à la lisibilité complexe du champ de la réception, aux usages de l’histoire, des historiens et des mémoires sociales, à l’écriture de l’histoire et plus particulièrement celle du « très contemporain »...

Dynamics of non-equilibrium membrane bud formation

The dynamical response of a lipid membrane to a local perturbation of its molecular symmetry is investigated theoretically. A density asymmetry between the two membrane leaflets is predominantly released by in-plane lipid diffusion or membrane curvature, depending upon the spatial extent of the perturbation. It may result in the formation of non-equilibrium structures (buds), for which a dynamical size selection is observed. A preferred size in the micrometer range is predicted, as a signature of the crossover between membrane and solvent dominated dynamical membrane response.Comment: 7 pages 3 figure

Mixed method versus full top-down microcosting for organ recovery cost assessment in a French hospital group

Background: The costing method used can change the results of economic evaluations. Choosing the appropriate method to assess the cost of organ recovery is an issue of considerable interest to health economists, hospitals, financial managers and policy makers in most developed countries. Objectives: The main objective of this study was to compare a mixed method, combining top-down microcosting and bottom-up microcosting versus full top-down microcosting to assess the cost of organ recovery in a French hospital group. The secondary objective was to describe the cost of kidney, liver and pancreas recovery from French databases using the mixed method. Methods: The resources consumed for each donor were identified and valued using the proposed mixed method and compared to the full top-down microcosting approach. Data on kidney, liver and pancreas recovery were collected from a medico-administrative French database for the years 2010 and 2011. Related cost data were recovered from the hospital cost accounting system database for 2010 and 2011. Statistical significance was evaluated at P < 0.05. Results: All the median costs for organ recovery differ significantly between the two costing methods (non-parametric test method; P < 0.01). Using the mixed method, the median cost for recovering kidneys was found to be €5155, liver recovery was €2528 and pancreas recovery was €1911. Using the full top-down microcosting method, median costs were found to be 21-36% lower than with the mixed method. Conclusion: The mixed method proposed appears to be a trade-off between feasibility and accuracy for the identification and valuation of cost components when calculating the cost of organ recovery in comparison to the full top-down microcosting approach

Matrix Isolation Infrared Spectroscopic and Theoretical Study of the Interaction of Water with Dimethyl Methylphosphonate

Matrix isolation infrared spectroscopy has been combined with theoretical calculations for the characterization of the 1:1 hydrogen-bonded complex between H2O and dimethyl methylphosphonate (DMMP). The symmetric O-H stretching mode was observed to shift 203 cm-1 to lower energy upon hydrogen bond formation, while a 32 cm-1 blue shift was noted for the H-O-H bending mode of the H2O subunit in the complex. These values compare extremely well with the (unscaled) shifts of -203 and +32 cm-1, respectively, that were calculated theoretically at the MP2/6-31+G** level. Additional perturbed modes of the DMMP subunit were observed, shifted relative to the parent band position. The greatest perturbation was to the P=O stretching mode near 1270 cm-1, where a shift of -17 cm-1 was observed (-21 cm-1 calculated theoretically). This suggests that the site of hydrogen bonding in the complex is at the P=O group, in agreement with theoretical calculations. The binding energy ΔE° for the 1:1 complex was calculated to be -7.7 kcal/mol

SOPROLIFE System: An Accurate Diagnostic Enhancer

Objectives. The aim of this study was to evaluate a light-emitting diode fluorescence tool, the SOPROLIFE light-induced fluorescence evaluator, and compare it to the international caries detection and assessment system-II (ICDAS-II) in the detection of occlusal caries. Methods. A total of 219 permanent posterior teeth in 21 subjects, with age ranging from 15 to 65 years, were examined. An intraclass correlation coefficient (ICC) was computed to assess the reliability between the two diagnostic methods. Results. The results showed a high reliability between the two methods (ICC = 0.92; IC = 0.901–0.940; P<0.001). The SOPROLIFE blue fluorescence mode had a high sensitivity (87%) and a high specificity (99%) when compared to ICDAS-II. Conclusion. Compared to the most used visual method in the diagnosis of occlusal caries lesions, the finding from this study suggests that SOPROLIFE can be used as a reproducible and reliable assessment tool. At a cut-off point, categorizing noncarious lesions and visual change in enamel, SOPROLIFE shows a high sensitivity and specificity. We can conclude that financially ICDAS is better than SOPROLIFE. However SOPROLIFE is easier for clinicians since it is a simple evaluation of images. Finally in terms of efficiency SOPROLIFE is not superior to ICDAS but tends to be equivalent with the same advantages

Long-Term Outcomes of Hematopoietic Stem Cell Transplantation for Severe Treatment-Resistant Autoimmune Cytopenia in Children

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French Roadmap for complex Systems 2008-2009

This second issue of the French Complex Systems Roadmap is the outcome of the Entretiens de Cargese 2008, an interdisciplinary brainstorming session organized over one week in 2008, jointly by RNSC, ISC-PIF and IXXI. It capitalizes on the first roadmap and gathers contributions of more than 70 scientists from major French institutions. The aim of this roadmap is to foster the coordination of the complex systems community on focused topics and questions, as well as to present contributions and challenges in the complex systems sciences and complexity science to the public, political and industrial spheres