510 research outputs found
Coherent flash of light emitted by a cold atomic cloud
When a resonant laser sent on an optically thick cold atomic cloud is
abruptly switched off, a coherent flash of light is emitted in the forward
direction. This transient phenomenon is observed due to the highly resonant
character of the atomic scatterers. We analyze quantitatively its
spatio-temporal properties and show very good agreement with theoretical
predictions. Based on complementary experiments, the phase of the coherent
field is reconstructed without interferometric tools.Comment: Submitted to Phys. Rev. Let
Blind Ghost Imaging
Ghost imaging is an unconventional optical imaging technique that
reconstructs the shape of an object combining the measurement of two signals:
one that interacted with the object, but without any spatial information, the
other containing spatial information, but that never interacted with the
object. Ghost imaging is a very flexible technique, that has been generalized
to the single-photon regime, to the time domain, to infrared and terahertz
frequencies, and many more conditions. Here we demonstrate that ghost imaging
can be performed without ever knowing the patterns illuminating the object, but
using patterns correlated with them, doesn't matter how weakly. As an
experimental proof we exploit the recently discovered correlation between the
reflected and transmitted light from a scattering layer, and reconstruct the
image of an object hidden behind a scattering layer using only the reflected
light, which never interacts with the object. This method opens new
perspectives for non-invasive imaging behind or within turbid media.Comment: 5 pages, 4 figure
Correlations between reflected and transmitted intensity patterns emerging from opaque disordered media
The propagation of monochromatic light through a scattering medium produces
speckle patterns in reflection and transmission, and the apparent randomness of
these patterns prevents direct imaging through thick turbid media. Yet, since
elastic multiple scattering is fundamentally a linear and deterministic
process, information is not lost but distributed among many degrees of freedom
that can be resolved and manipulated. Here we demonstrate experimentally that
the reflected and transmitted speckle patterns are correlated, even for opaque
media with thickness much larger than the transport mean free path, proving
that information survives the multiple scattering process and can be recovered.
The existence of mutual information between the two sides of a scattering
medium opens up new possibilities for the control of transmitted light without
any feedback from the target side, but using only information gathered from the
reflected speckle.Comment: 6 pages, 4 figure
Cooperative Emission of a Coherent Superflash of Light
We investigate the transient coherent transmission of light through an
optically thick cold stron-tium gas. We observe a coherent superflash just
after an abrupt probe extinction, with peak intensity more than three times the
incident one. We show that this coherent superflash is a direct signature of
the cooperative forward emission of the atoms. By engineering fast transient
phenomena on the incident field, we give a clear and simple picture of the
physical mechanisms at play.Comment: 4 Fig., 5 page
Spatial coherence in complex photonic and plasmonic systems
The concept of cross density of states characterizes the intrinsic spatial
coherence of complex photonic or plasmonic systems, independently on the
illumination conditions. Using this tool and the associated intrinsic coherence
length, we demonstrate unambiguously the spatial squeezing of eigenmodes on
disordered fractal metallic films, thus clarifying a basic issue in plasmonics
Synthesis of highly functionalized C₆₀ fullerene derivatives and their applications in material and life sciences
Highly functionalized fullerenes can be efficiently constructed by various techniques. However, the challenge is to synthesize highly symmetrical fullerenes. Recently, a number of X-ray structures have been disclosed showing the high symmetry of substituted fullerenes. By reviewing the major types of multi functionalized fullerenes through selected examples with a link to the structural assignments, the authors intend to give a concise overview to the specialist in the field and to provide the non-specialist with a tool box of possibilities
Developmental motor problems and health-related quality of life in 5-year-old children born extremely preterm: A European cohort study
Aim To measure the association between cerebral palsy (CP) and non-CP-related movement difficulties and health-related quality of life (HRQoL) among 5-year-old children born extremely preterm (<28 weeks gestational age). Method We included 5-year-old children from a multi-country, population-based cohort of children born extremely preterm in 2011 to 2012 in 11 European countries (n = 1021). Children without CP were classified using the Movement Assessment Battery for Children, Second Edition as having significant movement difficulties (<= 5th centile of standardized norms) or being at risk of movement difficulties (6th-15th centile). Parents reported on a clinical CP diagnosis and HRQoL using the Pediatric Quality of Life Inventory. Associations were assessed using linear and quantile regressions. Results Compared to children without movement difficulties, children at risk of movement difficulties, with significant movement difficulties, and CP had lower adjusted HRQoL total scores (beta [95% confidence interval] = -5.0 [-7.7 to -2.3], -9.1 [-12.0 to -6.1], and - 26.1 [-31.0 to -21.2]). Quantile regression analyses showed similar decreases in HRQoL for all children with CP, whereas for children with non-CP-related movement difficulties, reductions in HRQoL were more pronounced at lower centiles. Interpretation CP and non-CP-related movement difficulties were associated with lower HRQoL, even for children with less severe difficulties. Heterogeneous associations for non-CP-related movement difficulties raise questions for research about mitigating and protective factors.Faculdade de Ciencias e Tecnologia, Universidade Nova de Lisboa, Grant/Award Number: SFRH/BPD/117597/2016; Horizon 2020 Framework Programme, Grant/Award Number: No 633724 and No 733280; Seventh Framework Programme, Grant/Award Number: No 25988
Bayesian modelling of an absolute chronology for Egypt's 18th Dynasty by astrophysical and radiocarbon methods
Only a few astrophysical points and synchronisms listed in texts provide anchor points for the absolute chronology of Ancient Egypt. At first we will show how we can re-calculate some of these anchor points by using Sothic dating based on the arcus visionis method, and modelling lunar dates using a Bayesian approach. Then, we will discuss two radiocarbon studies carried out on short-lived Egyptian materials held at the Louvre Museum that could be attributed to particular reigns or other precise periods. Using a Bayesian approach, these dates were combined with the known order of succession and the lengths of reigns. Sothic and lunar dates were integrated as priors in the model. This approach has led to a new proposal for the absolute chronology of Egypt's 18th Dynasty
Variations in patterns of care across neonatal units and their associations with outcomes in very preterm infants: the French EPIPAGE-2 cohort study
OBJECTIVES: To describe patterns of care for very preterm (VP) babies across neonatal intensive care units (NICUs) and associations with outcomes. DESIGN: Prospective cohort study, EPIPAGE-2. SETTING: France, 2011. PARTICIPANTS: 53 (NICUs); 2135 VP neonates born at 27 to 31 weeks. OUTCOME MEASURES: Clusters of units, defined by the association of practices in five neonatal care domains - respiratory, cardiovascular, nutrition, pain management and neurodevelopmental care. Mortality at 2 years corrected age (CA) or severe/moderate neuro-motor or sensory disabilities and proportion of children with scores below threshold on the neurodevelopmental Ages and Stages Questionnaire (ASQ). METHODS: Hierarchical cluster analysis to identify clusters of units. Comparison of outcomes between clusters, after adjustment for potential cofounders. RESULTS: Three clusters were identified: Cluster 1 with higher proportions of neonates free of mechanical ventilation at 24 hours of life, receiving early enteral feeding, and neurodevelopmental care practices (26 units; n=1118 babies); Cluster 2 with higher levels of patent ductus arteriosus and pain screening (11 units; n=398 babies); Cluster 3 with higher use of respiratory, cardiovascular and pain treatments (16 units; n=619 babies). No difference was observed between clusters for the baseline maternal and babies' characteristics. No differences in outcomes were observed between Clusters 1 and 3. Compared with Cluster 1, mortality at 2 years CA or severe/moderate neuro-motor or sensory disabilities was lower in Cluster 2 (adjusted OR 0.46, 95% CI 0.25 to 0.84) but with higher proportion of children with an ASQ below threshold (adjusted OR 1.49, 95% CI 1.07 to 2.08). CONCLUSION: In French NICUs, care practices for VP babies were non-randomly associated. Differences between clusters were poorly explained by unit or population differences, but were associated with mortality and development at 2 years. Better understanding these variations may help to improve outcomes for VPT babies, as it is likely that some of these discrepancies are unwarranted
eIF4A RNA Helicase Associates with Cyclin-Dependent Protein Kinase A in Proliferating Cells and is Modulated by Phosphorylation
Eukaryotic initiation factor 4A (eIF4A) is a highly conserved RNA-stimulated ATPase and helicase involved in the initiation of messenger RNA translation. Previously, we found that eIF4A interacts with cyclin-dependent kinase A (CDKA), the plant ortholog of mammalian CDK1. Here, we show that this interaction occurs only in proliferating cells where the two proteins coassociate with 5′-cap-binding protein complexes, eIF4F or the plant-specific eIFiso4F. CDKA phosphorylates eIF4A on a conserved threonine residue (threonine-164) within the RNA-binding motif 1b TPGR. In vivo, a phospho-null (APGR) variant of the Arabidopsis (Arabidopsis thaliana) eIF4A1 protein retains the ability to functionally complement a mutant (eif4a1) plant line lacking eIF4A1, whereas a phosphomimetic (EPGR) variant fails to complement. The phospho-null variant (APGR) rescues the slow growth rate of roots and rosettes, together with the ovule-abortion and late-flowering phenotypes. In vitro, wild-type recombinant eIF4A1 and its phospho-null variant both support translation in cell-free wheat germ extracts dependent upon eIF4A, but the phosphomimetic variant does not support translation and also was deficient in ATP hydrolysis and helicase activity. These observations suggest a mechanism whereby CDK phosphorylation has the potential to down-regulate eIF4A activity and thereby affect translation
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