319 research outputs found

    The Mn site in Mn-doped Ga-As nanowires: an EXAFS study

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    We present an EXAFS study of the Mn atomic environment in Mn-doped GaAs nanowires. Mn doping has been obtained either via the diffusion of the Mn used as seed for the nanowire growth or by providing Mn during the growth of Au-induced wires. As a general finding, we observe that Mn forms chemical bonds with As but is not incorporated in a substitutional site. In Mn-induced GaAs wires, Mn is mostly found bonded to As in a rather disordered environment and with a stretched bond length, reminiscent of that exhibited by MnAs phases. In Au-seeded nanowires, along with stretched Mn-As coordination we have found the presence of Mn in a Mn-Au intermetallic compound.Comment: This is an author-created, un-copyedited version of an article accepted for publication in Semiconductor Science and Technology. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The definitive publisher-authenticated version is available online at doi:10.1088/0268-1242/27/8/08500

    Towards a Geological Information System: the CARGeo System and the Regione Lombardia Geological Database.

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    In the framework of the national mapping program «CARGNew Italian Geological Map at 1:50.000 scale», Regione Lombardia is generating a detailed map (1:10.000 scale) of its territory. Surveying criteria have been carefully defined in order to produce homogeneous geological maps: geological survey has been performed at the 1:10.000 scale, and data have been stored in a GIS-oriented database. The detailed survey scale improved the geological knowledge: the new maps represent an important tool for territorial planning requirements of public administrations and engineering geologists (e.g. in hydrogeological and seismic risk evaluation). Field geologists performed data input in the geological data base by alternating field campaigns and data input throughout the year, taking advantage of periods when field activities are slackened (i.e. according to climate conditions). In this way, data entry is nearly synchronous with data collection, and field data become quickly accessible. Data entry by the field geologists on one side slows down the field activity, however, it guarantees a precise digitalization of geometric data and a correct attribute assignment, allowing to optimize working time. To allow the data entry to non-GIS-specialized users, we developed an ArcViewÂź-VisualBasicÂź-MSAccessÂź application, enabling the simultaneous acquisition of geometric and alphanumeric data. Data base management and cartographic production are performed with ArcInfoÂź, through specific procedures which, after data reorganization and control (both alphanumeric and geometric), lead to the final cartographic output at different scales. The 1:10.000 geological database is migrated in the ArcSDE structure and prepared for data view, query and download (www.cartografia.regione.lombardia.it/cargweb) using ESRI (ArcIMS) tools. From the 1:10.000 geological database we derived the database for the 1:50.000 CARG maps by both automatic and manual generalization according to the CARG-APAT standards. During the different phases of the project, several problems arose, due to both project organization and data storage system (from data collection in the field to elaboration and digitalization, and, in case, to final publication). – Data collection: the survey activity was divided between «bedrock » and «quaternary» specialists. The double survey provided a high-quality geological description of the territory, but slowed the generation of the data-flow. Based on this experience, the last assigned areas are surveyed by a single geologist, under the supervision of quaternary and bedrock experts. – Users feedback: geologists are normally used to draw their maps on paper; learning how to produce electronic maps can be difficult, and the software tools have to be studied very carefully and present user friendly interfaces. Nevertheless, in our experience, a training period has to be planned, and geologists have to be supported by a GIS expert, who can understand their needs and modify the software accordingly. – System architecture: the ArcViewÂź-VisualBasicÂź-MSAccessÂź (Windows platform) – ArcInfoÂź (UNIX platform) environment, revealed problems in the client-server stability of an earlier version; some unsolved troubles remain, mainly related to the network architecture. The presence in the CARG-Regione Lombardia crew of consultant geologists, experienced and trained in collection, analysis and data entry in the final database, accelerated the critical phases of: – Data base derivation from Regione Lombardia dataset to CARG-APAT standard

    Alteração nos teores de carbono e fósforo orgùnico em um Latossolo após 23 anos sob diferentes preparos de solo e culturas de inverno

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    O fósforo (P) orgùnico é importante fonte de fosfato para as plantas, tanto em ambientes naturais quanto em solos cultivados. O cultivo de plantas com alta capacidade de reciclagem de P pode aumentar a importùncia das formas orgùnicas na disponibilização de fosfato, especialmente quando o solo não é revolvido O presente estudo objetivou avaliar em um solo muito argiloso sob longo período de cultivo (i) o efeito de diferentes preparos de solo e (ii) o efeito do cultivo de diferentes espécies de plantas de inverno, no teor de carbono e fósforo orgùnico do solo. Em 1986 foi estabelecido o experimento com seis tratamentos de inverno (tremoço azul, ervilhaca peluda, aveia preta, nabo forrageiro, trigo e pousio) implantados num Latossolo Vermelho Aluminoférrico na região sudoeste do Paranå, sob sistema plantio direto (SPD) e sistema de cultivo convencional (SCC). As amostras de solo foram coletadas em outubro de 2009 em cinco profundidades (0-5, 5-10, 10-20, 20-30 e 30-40 cm). Sistemas de manejo do solo conservacionistas, como o SPD, aumentam o teor de carbono e fósforo orgùnico total do solo da camada superficial comparativamente ao SCC, mas não é suficiente para recuperar os teores de carbono orgùnico total original do solo sob mata nativa. O cultivo de plantas durante o inverno aumenta o teor de carbono orgùnico total do solo independentemente do sistema de manejo de solo adotado, mas não altera o teor de P orgùnico total do solo estimado pelo método de ignição

    The Assertive Brain : Anterior Cingulate Phosphocreatine plus Creatine Levels Correlate With Self-Directedness in Healthy Adolescents

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    Despite various advances in the study of the neurobiological underpinnings of personality traits, the specific neural correlates associated with character and temperament traits are not yet fully understood. Therefore, this study aims to fill this gap by exploring the biochemical basis of personality, which is explored with the temperament and character inventory (TCI), during brain development in a sample of adolescents. Twenty-six healthy adolescents (aged between 13 and 21 years; 9 males and 18 females) with behavioral and emotional problems underwent a TCI evaluation and a 3T single-voxel proton magnetic resonance spectroscopy (1H MRS) acquisition of the anterior cingulate cortex (ACC). Absolute metabolite levels were estimated using LCModel: significant correlations between metabolite levels and selective TCI scales were identified. Specifically, phosphocreatine plus creatine (PCr+Cre) significantly correlated with self-directedness, positively, and with a self-transcendence (ST), negatively, while glycerophosphocholine plus phosphocholine (GPC+PC) and myo-inositol negatively correlated with ST. To the best of our knowledge, this is the first study reporting associations of brain metabolites with personality traits in adolescents. Therefore, our results represent a step forward for personality neuroscience within the study of biochemical systems and brain structures

    IFI16 reduced expression is correlated with unfavorable outcome in chronic lymphocytic leukemia

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    Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. Its clinical course is typically indolent; however, based on a series of pathobiological, clinical, genetic, and phenotypic parameters, patient survival varies from less than 5 to more than 20 years. In this paper, we show for the first time that the expression of the interferon-inducible DNA sensor IFI16, a member of the PYHIN protein family involved in proliferation inhibition and apoptosis regulation, is associated with the clinical outcome in CLL. We studied 99 CLLs cases by immunohistochemistry and 10 CLLs cases by gene expression profiling. We found quite variable degrees of IFI16 expression among CLLs cases. Noteworthy, we observed that a reduced IFI16 expression was associated with a very poor survival, but only in cases with ZAP70/CD38 expression. Furthermore, we found that IFI16 expression was associated with a specific gene expression signature. As IFI16 can be easily detected by immunohistochemistry or flow cytometry, it may become a part of phenotypic screening in CLL patients if its prognostic role is confirmed in independent series

    Dutch elementary school children’s attribution of meaning to written pseudowords

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    Grade two through six elementary school Dutch children were asked to perform a lexical decision task including 90 pseudowords constructed by changing one or two letters in a Dutch word. Subsequently, the children were asked about the meaning of pseudowords they had not crossed out and that they, apparently, had considered to be words. Multiple regression analyses on the lexical decision task showed that the older children were more hindered by the morphemic structure of a pseudoword than by its orthographic neighbors. The younger children, in contrast, were less hindered by the morphemic structure of a pseudoword and more hindered by its orthographic neighbors. Word length was a (small) predictor only for grade 6. Moreover, the answers of the children reflected that in their construction of meanings for the pseudowords they were hindered both by the morphemic structure and by the orthographic neighbors of the pseudowords

    Clinical and experimental efficacy of gemtuzumab ozogamicin in core binding factor acute myeloid leukemia

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    Leukemia-initiating cells of core binding factor (CBF) acute myeloid leukemia (AML) likely derive from early committed hematopoietic precursors expressing CD33. As such, targeting CD33 could ameliorate the chance of cure of CBF AML patients. We compared 12 CBF AML patients treated with Fludarabine, Cytarabine, Idarubicin and Gemtuzumab Ozogamicin (FLAI-GO regimen) with 25 CBF AML patients treated with the same schedule, but without GO. With the limit of small numbers, we observed a consistent trend toward better overall survival, disease free survival and event free survival in the FLAI-GO group. We also demonstrated the ability of GO to induce the disappearance in vitro of the AML1-ETO molecular transcript in a polymerase chain reaction-positive graft without decreasing the clonogenic potential of CD34+/CD38- cells. This represent the proof of principle for using GO in a purging strategy before autologous stem cell transplantation. Therefore, our data argue in favor of the reinstitution of GO in the therapy of CBF AML

    Composição do mosto de videiras submetidas a modos de fornecimento de nitrogĂȘnio em solo arenoso.

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    XV Congresso Latino-Americano de Viticultura e Enologia E XIII Congresso Brasileiro de Viticultura e Enologia. Bento Gonçalves-RS, 3 a 7 de Novembro de 2015
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