CONDITION OF GLUTATHIONE (GSH) METABOLISM SYSTEM AT ALLOTRANSPLANTATION OF EMBRYONIC MUSCULE TISSUE AT RATS

This article presents the results of determination of the of reduced glutathione content, glutathione reductase and glutathione peroxidase during allotransplantation of the embryo muscle tissue. During the research there was carried out 2 kinds of surgery: 1st - allotransplantation of embryo muscle tissue; 2nd - surgery without replanting. To obtain embryos we used female rats from gestation 3-4 weeks. We took an abdominal muscle tissue from embryo that was hemmed to homologous tissue of the adult rat. The same procedure was carried out with femoral muscle tissue.It was found that allotransplantation of the embryo muscle tissue leads to an increasing of restored glutathione at day 7 of experiment in femoral and abdominal muscle of adult rat, leads the increasing of glutathione glutathione reductase activity in all researched tissues on day 7 of the experiment, except the femoral muscle of the adult rat. At experiment day 7 during surgery without replanting glutathione increased in femoral and abdominal muscle tissue, and activity of glutathione reductase increased only in the abdominal muscle, while activity of glutathione peroxidase in the abdominal muscle tissue decreased

Spatial variability of characteristics of the ice cover of the Rybinsky reservoir in winter 2022

The paper presents the results and a brief analysis of in-situ measurements of thickness and other characteristics of the ice cover of the Rybinsky reservoir, which took place during two expeditions in February and April 2022. In expeditions, 49 ice cores were taken, which provide enough information to evaluate the heterogeneity of the ice cover. The most accurate data were obtained for two profiles, which cross the reservoir from the north to the south and from the southwest to the northeast and coincide with two tracks of the satellite altimeter Jason-3. In 2022 ice cover of the Rybinsky reservoir was heterogeneous and made up several different ice layers. Combination and thickness of these layers were distributed unevenly over the surface of the reservoir and were changing over time. The most uneven distribution was observed in the winter: near the shore and in the southwest part of the reservoir ice cover consisted of black ice, central part of the reservoir was made of black ice and frazil ice and east part of the reservoir was made up black ice and white ice. In the spring, ice cover became much more homogeneous and consisted of thick layers of white ice and black ice

Pharmacoeconomic efficiency of the exhaled nitric oxide monitoring for the purpose of personalized basic therapy for children with atopic asthma

effectiveness of basic therapy for atopic asthma in children. Material and Methods. A 24-week, prospective, comparative, randomized, open-label study in parallel groups was performed. There were included 70 children with uncontrolled atopic asthma with high FeNO (FeNO>50ppb). There were evaluated the comparative efficacy of selection of basic therapy by using monthly monitoring of FeNO and criteria of asthma control in accordance with the recommendations of GINA (2011). Results. The cost / effective ratio (CER) for achievement of one permanent 12 week-control after 24 weeks of therapy in group of monitoring FeNO was 11433,26 rubles, which was 40% lower, than the CER in the comparison group (18382,99 rubles). Conclusion. The using of FeNO monitoring for a personalized correction of basic therapy in children with uncontrolled atopic asthma can reduce the cost of treatment and is also economically viable

[Changes in the level of sportsmen’s somatic health during the training of general endurance]

The 28 trained male athletes studied changes in somatic health after 7 weeks of classes aimed at developing general endurance. It is shown that with the preferred improvement in 10.7% of cases there is a deterioration of somatic health

Formation of submicron relief structures on the surface of sapphire substrates

An analysis of technologies that allow creating microrelief structures on the surface of sapphire substrates has been carried out. It is shown that the most effective method of forming relief structures with submicron dimensions is ion beam   etching through a protective mask formed by photolithography. The main problems in creating a microrelief on the surface of sapphire substrates are the removal of static electric charge in the process of ion beam  etching of the substrates, as well as obtaining a protective mask with windows of specified sizes, through which etching of the sapphire substrate is performed

Elastic double diffractive production of axial-vector \chi_c(1^{++}) mesons and the Landau-Yang theorem

We discuss exclusive elastic double diffractive axial-vector \chi_c(1^{+}) meson production in proton-antiproton collisions at the Tevatron. The amplitude for the process is derived within the k_t-factorisation approach with unintegrated gluon distribution functions (UGDFs). We show that the famous Landau-Yang theorem is not applicable in the case of off-shell gluons. Differential cross sections for different UGDFs are calculated. We compare exclusive production of \chi_c(1^+) and \chi_c(0^+). The contribution of \chi_c(1^+) to the J/\Psi + \gamma channel is smaller than that of the \chi_c(0^+) decay, but not negligible and can be measured. The numerical value of the ratio of the both contributions is almost independent of UGDFs modeling.Comment: 14 pages, 5 figures, a numerical error corrected, discussions extended, conclusions unchange

Thermal compression of atomic hydrogen on helium surface

We describe experiments with spin-polarized atomic hydrogen gas adsorbed on liquid $^{4}$He surface. The surface gas density is increased locally by thermal compression up to $5.5\times10^{12}$ cm$^{-2}$ at 110 mK. This corresponds to the onset of quantum degeneracy with the thermal de-Broglie wavelength being 1.5 times larger than the mean interatomic spacing. The atoms were detected directly with a 129 GHz electron-spin resonance spectrometer probing both the surface and the bulk gas. This, and the simultaneous measurement of the recombination power, allowed us to make accurate studies of the adsorption isotherm and the heat removal from the adsorbed hydrogen gas. From the data, we estimate the thermal contact between 2D hydrogen gas and phonons of the helium film. We analyze the limitations of the thermal compression method and the possibility to reach the superfluid transition in 2D hydrogen gas.Comment: 20 pages, 11 figure

Characteristics of plasma streams and optimization of operational regimes for magnetoplasma compressor

The main objective of these studies is characterization of dense xenon plasma streams generated by magnetoplasma compressor (MPC) in different operational regimes. Optimization of plasma compression in MPC allows increase of the plasma stream pressure up to 22…25 bar, average temperature of electrons of 10…20 eV and plasma stream velocity varied in the range of (2…9)×10⁶ cm/s depending on operation regime. Spectroscopy measurements demonstrate that in these conditions most of Xe spectral lines are reabsorbed. In the case of known optical thickness, the real value of electron density can be calculated with accounting self-absorption. Estimations of optical thickness were performed and resulting electron density in focus region was evaluated as 10¹⁸ cm⁻³. Remove selectedПроведено експерименти з оптимізації режимів роботи МПК та виміряно параметри плазмових потоків при роботі на ксеноні. Проаналізовано розподіли тиску в плазмовому потоці, швидкість та температура плазми. Спектроскопічні вимірювання показали, що більшість спектральних ліній ксенону самопоглинені. У випадку відомої оптичної товщини, реальна електронна густина може бути обчислена з урахуванням ефекту самопоглинання. Були проведені оцінки оптичної товщини, в результаті чого розрахована величина концентрації електронів в області компресії – 10¹⁸ см⁻³.Проведены эксперименты по оптимизации режимов работы МПК, измерены параметры плазменных потоков при работе на ксеноне. Проанализированы распределения давления в плазменном потоке, скорость и температура плазмы. Спектроскопические измерения показали, что большинство спектральных линий ксенона самопоглощены. В случае известной оптической толщины реальная электронная плотность может быть вычислена с учетом эффекта самопоглощения. Проведены оценки оптической толщины, в результате чего рассчитано значение концентрации электронов в области компрессии – 10¹⁸ см⁻³

Comparative Study of Multifragmentation of Gold Nuclei Induced by Relativistic Protons, 4^4He, and 12^{12}C

Multiple emission of intermediate-mass fragments has been studied for the collisions of p, $^4$He and $^{12}$C on Au with the $4\pi$ setup FASA. The mean IMF multiplicities (for the events with at least one IMF) are saturating at the value of $2.2\pm0.2$ for the incident energies above 6 GeV. The observed IMF multiplicities cannot be described in a two-stage scenario, a fast cascade followed by a statistical multifragmentation. Agreement with the measured IMF multiplicities is obtained by introducing an intermediate phase and modifying empirically the excitation energies and masses of the remnants. The angular distributions and energy spectra from the p-induced collisions are in agreement with the scenario of ``thermal'' multifragmentation of a hot and diluted target spectator. In the case of $^{12}$C+Au(22.4 GeV) and $^4$He(14.6 GeV)+Au collisions, deviations from a pure thermal break-up are seen in the energy spectra of the emitted fragments, which are harder than those both from model calculations and from the measured ones for p-induced collisions. This difference is attributed to a collective flow.Comment: 33 pages 15 figures, accepted in Nucl. Phys.

Spreading Dynamics of Polymer Nanodroplets

The spreading of polymer droplets is studied using molecular dynamics simulations. To study the dynamics of both the precursor foot and the bulk droplet, large drops of ~200,000 monomers are simulated using a bead-spring model for polymers of chain length 10, 20, and 40 monomers per chain. We compare spreading on flat and atomistic surfaces, chain length effects, and different applications of the Langevin and dissipative particle dynamics thermostats. We find diffusive behavior for the precursor foot and good agreement with the molecular kinetic model of droplet spreading using both flat and atomistic surfaces. Despite the large system size and long simulation time relative to previous simulations, we find no evidence of hydrodynamic behavior in the spreading droplet.Comment: Physical Review E 11 pages 10 figure