ВНУТРИПЕЧЕНОЧНАЯ ИНДУКЦИЯ ЭНДОГЕННОГО S-АДЕНОЗИЛ-L-МЕТИОНИНА НА ФОНЕ РАЗЛИЧНЫХ ПУТЕЙ ВВЕДЕНИЯ КОМПЛЕКСА МЕТИОНИН+СУКЦИНАТ И ЕЕ РОЛЬ В КОРРЕКЦИИ ЛЕКАРСТВЕННОГО ПОРАЖЕНИЯ ПЕЧЕНИ

A comparative study of the level of endogenous S-adenosyl-L-methionine (SAM) with other hepatoprotectors in pharmacological correction of liver drug lesion. Among 117 male rats. It has been shown that among antituberculous drugs only Remaxol and Runihol were causing significant increase in endogenic SAM. Taking into account the amelioration of lab results as well as histological condition of the liver against the background of Remaxol treatment as well as positive effect of Runihol treatment upon cholestasis, one can draw a conclusion  upon the importance of succinic acid together with SAM induction as a part of hepatoprotective effect of the drug.  Reamberin, which contains succinic acid without methionine also shows hepatoprotective qualities and doesn’t induce endogenous SAM production. Positive therapeutic effect of exogenous SAM regardless the way of administration doesn’t correlate with endogenous SAM induction, and is associated with the external hepatocyte cell membrane restoration.     Проведено сравнительное экспериментальное изучение уровня эндогенного S-аденозил-L-метионина (SAM) с другими гепатопротекторными препаратами при фармакологической коррекции лекарственного поражениях печени на 117 беспородных крысах-самцах. Установлено, что при воздействии противотуберкулезных препаратов только Ремаксол и Рунихол вызывали достоверный рост уровня эндогенного SAM. Учитывая улучшение лабораторных показателей и гистологической картины печени на фоне терапии Ремаксолом, а также положительное влияние Рунихола на проявления синдрома холестаза, можно сделать вывод о важности янтарной кислоты наряду с индукцией SAM в гепатопротекторном эффекте препаратов. Реамберин, содержащий янтарную кислоту без метионина, также обладает гепатопротекторным эффектом и не вызывает индукцию эндогенного SAM. Положительный терапевтический эффект экзогенного SAM при различных путях введения не коррелирует с индукцией эндогенного SAM, а связан с восстановлением клеточной мембраны гепатоцитов извне

Two loop effective kaehler potential of (non-)renormalizable supersymmetric models

We perform a supergraph computation of the effective Kaehler potential at one and two loops for general four dimensional N=1 supersymmetric theories described by arbitrary Kaehler potential, superpotential and gauge kinetic function. We only insist on gauge invariance of the Kaehler potential and the superpotential as we heavily rely on its consequences in the quantum theory. However, we do not require gauge invariance for the gauge kinetic functions, so that our results can also be applied to anomalous theories that involve the Green-Schwarz mechanism. We illustrate our two loop results by considering a few simple models: the (non-)renormalizable Wess-Zumino model and Super Quantum Electrodynamics.Comment: 1+26 pages, LaTeX, 6 figures; a missing diagram added and typos correcte

FIRST RADIOCARBON RESULTS OF ONEGA LAKE BOTTOM SEDIMENTS BASED ON CONVENTIONAL AND AMS METHODS

48-5

Spallative ablation of dielectrics by X-ray laser

Short laser pulse in wide range of wavelengths, from infrared to X-ray, disturbs electron-ion equilibrium and rises pressure in a heated layer. The case where pulse duration $\tau_L$ is shorter than acoustic relaxation time $t_s$ is considered in the paper. It is shown that this short pulse may cause thermomechanical phenomena such as spallative ablation regardless to wavelength. While the physics of electron-ion relaxation on wavelength and various electron spectra of substances: there are spectra with an energy gap in semiconductors and dielectrics opposed to gapless continuous spectra in metals. The paper describes entire sequence of thermomechanical processes from expansion, nucleation, foaming, and nanostructuring to spallation with particular attention to spallation by X-ray pulse

On limit theorems for continued fractions

It is shown that for sums of functionals of digits in continued fraction expansion the Kolmogorov-Feller weak laws of large numbers and the Khinchine-L\'evy-Feller-Raikov characterization of the domain of attraction of the normal law hold.Comment: 16 page

Unraveling the magnetic properties of BiFe0.5Cr0.5O3thin films

We investigate the structural, chemical, and magnetic properties on BiFe0.5Cr0.5O3(BFCO) thin films grown on (001) (110) and (111) oriented SrTiO3(STO) substrates by x-ray magnetic circular dichroism and x-ray diffraction. We show how highly pure BFCO films, differently from the theoretically expected ferrimagnetic behavior, present a very weak dichroic signal at Cr and Fe edges, with both moments aligned with the external field. Chemically sensitive hysteresis loops show no hysteretic behavior and no saturation up to 6.8 T. The linear responses are induced by the tilting of the Cr and Fe moments along the applied magnetic field

Green function techniques in the treatment of quantum transport at the molecular scale

The theoretical investigation of charge (and spin) transport at nanometer length scales requires the use of advanced and powerful techniques able to deal with the dynamical properties of the relevant physical systems, to explicitly include out-of-equilibrium situations typical for electrical/heat transport as well as to take into account interaction effects in a systematic way. Equilibrium Green function techniques and their extension to non-equilibrium situations via the Keldysh formalism build one of the pillars of current state-of-the-art approaches to quantum transport which have been implemented in both model Hamiltonian formulations and first-principle methodologies. We offer a tutorial overview of the applications of Green functions to deal with some fundamental aspects of charge transport at the nanoscale, mainly focusing on applications to model Hamiltonian formulations.Comment: Tutorial review, LaTeX, 129 pages, 41 figures, 300 references, submitted to Springer series "Lecture Notes in Physics

Heavy quarkonium: progress, puzzles, and opportunities

A golden age for heavy quarkonium physics dawned a decade ago, initiated by the confluence of exciting advances in quantum chromodynamics (QCD) and an explosion of related experimental activity. The early years of this period were chronicled in the Quarkonium Working Group (QWG) CERN Yellow Report (YR) in 2004, which presented a comprehensive review of the status of the field at that time and provided specific recommendations for further progress. However, the broad spectrum of subsequent breakthroughs, surprises, and continuing puzzles could only be partially anticipated. Since the release of the YR, the BESII program concluded only to give birth to BESIII; the $B$-factories and CLEO-c flourished; quarkonium production and polarization measurements at HERA and the Tevatron matured; and heavy-ion collisions at RHIC have opened a window on the deconfinement regime. All these experiments leave legacies of quality, precision, and unsolved mysteries for quarkonium physics, and therefore beg for continuing investigations. The plethora of newly-found quarkonium-like states unleashed a flood of theoretical investigations into new forms of matter such as quark-gluon hybrids, mesonic molecules, and tetraquarks. Measurements of the spectroscopy, decays, production, and in-medium behavior of c\bar{c}, b\bar{b}, and b\bar{c} bound states have been shown to validate some theoretical approaches to QCD and highlight lack of quantitative success for others. The intriguing details of quarkonium suppression in heavy-ion collisions that have emerged from RHIC have elevated the importance of separating hot- and cold-nuclear-matter effects in quark-gluon plasma studies. This review systematically addresses all these matters and concludes by prioritizing directions for ongoing and future efforts.Comment: 182 pages, 112 figures. Editors: N. Brambilla, S. Eidelman, B. K. Heltsley, R. Vogt. Section Coordinators: G. T. Bodwin, E. Eichten, A. D. Frawley, A. B. Meyer, R. E. Mitchell, V. Papadimitriou, P. Petreczky, A. A. Petrov, P. Robbe, A. Vair