46 research outputs found

    Satisfying needs through food and drink

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    Essen ist nicht nur Voraussetzung für das Überleben, es dient darüber hinaus auch weiterengrundlegenden psychischen und sozialen Bedürfnissen. Die Steuerung von Hunger und Sättigung erfolgt daher sowohl über die Homöostase als auch durch psychische und soziale Faktoren, die ebenso Einfluss auf die cerebrale Steuerung nehmen. Eine Aufgabe der Ernährungs- und Verbraucherbildung ist, auf der Basis von Wissen über diese Zusammenhänge Essverhalten verstehen, reflektieren und gestalten zu können. (DIPF/Orig.)Food is not only a prerequisite for survival, but it also serves other basic psychological and social needs. The control of hunger and satiety is therefore affected both through homeostasis and through psychological and social factors that also influence cerebral control. One task of nutrition and consumer education is to understand, reflect, and shape eating behaviour based on knowledge about these interrelationships. (DIPF/Orig.

    Professional training in nutrition education. Participants and implementation framework in primary school

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    Non-formale Fortbildungsangebote für die Ernährungspraxis werden zunehmend angeboten und in Anspruch genommen. In der vorliegenden Untersuchung wurden die Teilnehmenden eines bundesweiten Fortbildungsangebots, die Ernährungspraxis in der Grundschule aufgreifen möchten, hinsichtlich ihrer Qualifikation und Kompetenzen sowie den jeweiligen Rahmenbedingungen ihrer Tätigkeit in der Grundschule untersucht. (DIPF/Orig.)Non-formal professional training opportunities in nutrition education are increasingly being offered and taken up. The present study examined the participants in a nationwide non-formal training in nutrition education, who are interested in taking up nutritional education into primary schools, with regard to their qualifications, competencies and implementation framework. (DIPF/Orig.

    Full system test and early preliminary acceptance Europe results for CRIRES+

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    CRIRES+ is the new high-resolution NIR echelle spectrograph intended to be operated at the platform B of VLT Unit telescope UT3. It will cover from Y to M bands (0.95-5.3um) with a spectral resolution of R = 50000 or R=100000. The main scientific goals are the search of super-Earths in the habitable zone of low-mass stars, the characterisation of transiting planets atmosphere and the study of the origin and evolution of stellar magnetic fields. Based on the heritage of the old adaptive optics (AO) assisted VLT instrument CRIRES, the new spectrograph will present improved optical layout, a new detector system and a new calibration unit providing optimal performances in terms of simultaneous wavelength coverage and radial velocity accuracy (a few m/s). The total observing efficiency will be enhanced by a factor of 10 with respect to CRIRES. An innovative spectro-polarimetry mode will be also offered and a new metrology system will ensure very high system stability and repeatability. Fiinally, the CRIRES+ project will also provide the community with a new data reduction software (DRS) package. CRIRES+ is currently at the initial phase of its Preliminary Acceptance in Europe (PAE) and it will be commissioned early in 2019 at VLT. This work outlines the main results obtained during the initial phase of the full system test at ESO HQ Garching

    Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

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    Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

    Improved sensitivity of an acid sphingomyelinase activity assay using a C6:0 sphingomyelin substrate

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    Short-chain C6-sphingomyelin is an artificial substrate that was used in an acid sphingomyelinase activity assay for a pilot screening study of patients with Niemann–Pick disease types A and B. Using previously published multiplex and single assay conditions, normal acid sphingomyelinase activity levels (i.e. false negative results) were observed in two sisters with Niemann–Pick B who were compound heterozygotes for two missense mutations, p.C92W and p.P184L, in the SMPD1 gene. Increasing the sodium taurocholate detergent concentration in the assay buffer lowered the activity levels of these two patients into the range observed with other patients with clear separation from normal controls

    Canine antibodies against salivary recombinant proteins of phlebotomus perniciosus: A longitudinal study in an endemic focus of canine Leishmaniasis

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    BACKGROUND:Phlebotomine sand flies are vectors of Leishmania parasites. During blood feeding, sand flies deposit into the host skin immunogenic salivary proteins which elicit specific antibody responses. These anti-saliva antibodies enable an estimate of the host exposure to sand flies and, in leishmaniasis endemic areas, also the risk for Leishmania infections. However, the use of whole salivary gland homogenates as antigen has several limitations, and therefore, recombinant salivary proteins have been tested to replace them in antibody detection assays. In this study, we have used for the first time sand fly salivary recombinant proteins in a longitudinal field study on dogs. METHODOLOGY/PRINCIPAL FINDINGS:Sera from dogs naturally exposed to P. perniciosus bites over two consecutive transmission seasons in a site endemic for canine leishmaniasis (CanL) were tested at different time points by ELISA for the antibodies recognizing whole saliva, single salivary 43 kDa yellow-related recombinant protein (rSP03B), and a combination of two salivary recombinant proteins, 43 kDa yellow-related protein and 35.5 kDa apyrase (rSP01). Dogs were also tested for Leishmania infantum positivity by serology, culture, and PCR and the infection status was evaluated prospectively. We found a significant association between active CanL infection and the amount of anti-P. perniciosus saliva antibodies. Importantly, we detected a high correlation between IgG antibodies recognizing rSP03B protein and the whole salivary antigen. The kinetics of antibody response showed for both a whole saliva and rSP03B a similar pattern that was clearly related to the seasonal abundance of P. perniciosus. CONCLUSIONS:These results suggest that P. perniciosus rSP03B protein is a valid alternative to whole saliva and could be used in large-scale serological studies. This novel method could be a practical and economically-sound tool to detect the host exposure to sand fly bites in CanL endemic areas

    Programa de prevención de drogodependencias

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    Se trata de un plan preventivo sobre el consumo de todo tipo de sustancias que puedan crear adicción. Este plan es tratado en los tres niveles de concreción del currículo: Proyecto Educativo de Centro, Proyecto Curricular de etapa y programación de aula. Entre los aspectos tratados destacan: los hábitos alimentarios, higiénicos y de descanso nocturno; el consumo de golosinas y sustancias nocivas; el comportamiento dependiente (televisión, videojuegos, chucherías, etc.); la utilización del tiempo libre y el nivel de participación del alumnado en el centro. Las actividades se desarrollan en dos ámbitos: curricular (elaboración de carteles, exposición de trabajos, debates, etc.) y extracurricular y comunitario (deportes, cerámica, música, dramatización, etc.). Incluye una unidad didáctica para Infantil sobre los alimentos, otra para el primer y segundo ciclos de Primaria sobre higiene y salud y otra sobre publicidad y consumo para el tercer ciclo.Madrid (Comunidad Autónoma). Consejería de Educación y Cultura. Ministerio de Educación y Cultura. Ayuntamiento de MadridMadridMadrid (Comunidad Autónoma). Subdirección General de Formación del Profesorado. CRIF Las Acacias; General Ricardos 179 - 28025 Madrid; Tel. + 34915250893ES
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