Living with difference in hyper-diverse areas: how important are encounters in semi-public spaces?

Urban populations increasingly diversify in their socio-economic, cultural, religious and linguistic profiles as well as in their lifestyles, attitudes and activity patterns. This hyper-diversification can complicate feelings of belonging and community. Since diversity is negotiated at the neighbourhood level, micro spaces are central in building communities. Micro spaces tend to be semi-public and stimulate diverse groups to intermingle, which results in on–off as well as repetitive and structural interactions. Understanding the creation and impact of encounters is central to capturing contemporary notions of belonging and living with difference. This paper compares encounters experienced in two semi-public spaces in the hyper-diverse neighbourhood of Feyenoord in Rotterdam, the Netherlands. Although encounters at the library were lighter and shorter than at the community-centre, all positively impact collective life in the neighbourhood. At the community-centre, encounters result in light as well as deeper relationships, making visitors feel more at ‘home’ because they recognize others elsewhere in the neighbourhood. At the library, encounters are lighter but visitors become familiar with diversity, making them feel more at ‘home’ and safe in their neighbourhood as well. The study suggests that fleeting encounters require more serious attention within the context of negotiating diversity

Meeting spaces: everyday spaces of multicultural encounter in Glasgow

This thesis is about spaces of multicultural encounter, and their potential to facilitate connections and relationships, of differing depth and duration, to emerge between individuals and groups who live in the North and West of Glasgow, nurturing precarious yet progressive forms of living together in the city. Tracing people’s experiences of encounters across ethnic, cultural, religious and other differences, and their intersections, this thesis foregrounds the micro politics of encounter, connection making and belonging. I argue that emergent connections and relations, many of them seemingly banal and small, often bleed out beyond the immediate moment and specific site of encounter, impacting/changing wider socio-political imaginaries and narratives of nationhood, community and belonging in Scottish society. Critically, I can demonstrate that mundane and ‘everyday’ spaces of proximity and association play a key role in the unfolding of these processes. In accounting for the unevenness of people’s lived realities, and approaching encounters as sites of different co-existing trajectories, this thesis makes important contributions to relevant scholarship on the politics and geographies of everyday encounter, the spatialities of intersectionality, and the significance of localizing narratives of belonging and nationhood in specific contexts and localities in Glasgow and Scotland. In three empirical chapters, this thesis draws upon feminist theories to dissect the various ways in which people’s complex and multi-layered identifications and positionalities intersect and become articulated in moments of multicultural encounter in mundane spaces, including local cafes, public libraries and community centers. Emphasizing the histories and geographies of place, it frames encounters with/across difference as moments of opportunity, holding the potential for both relations of connection and understanding and disconnection and tension to emerge between people differently situated in society, and towards each other. By making lucid the ‘practice’ of racialization, the thesis draws attention to embodied encounters and relational practices, always emotional and agentic, as small yet decidedly political acts that may unsettle, shift and disrupt wider discourses and dominant notions of place, identity and belonging in Glasgow, and wider society. In this respect, the thesis aims to explore contestations, articulations and entanglements of ‘being together in difference’ in and beyond local places, as people whose bodies and identities are constructed as other/visible/strange/different inhabit the city

Higher COVID-19 pneumonia risk associated with anti-IFN-α than with anti-IFN-ω auto-Abs in children

We found that 19 (10.4%) of 183 unvaccinated children hospitalized for COVID-19 pneumonia had autoantibodies (auto-Abs) neutralizing type I IFNs (IFN-alpha 2 in 10 patients: IFN-alpha 2 only in three, IFN-alpha 2 plus IFN-omega in five, and IFN-alpha 2, IFN-omega plus IFN-beta in two; IFN-omega only in nine patients). Seven children (3.8%) had Abs neutralizing at least 10 ng/ml of one IFN, whereas the other 12 (6.6%) had Abs neutralizing only 100 pg/ml. The auto-Abs neutralized both unglycosylated and glycosylated IFNs. We also detected auto-Abs neutralizing 100 pg/ml IFN-alpha 2 in 4 of 2,267 uninfected children (0.2%) and auto-Abs neutralizing IFN-omega in 45 children (2%). The odds ratios (ORs) for life-threatening COVID-19 pneumonia were, therefore, higher for auto-Abs neutralizing IFN-alpha 2 only (OR [95% CI] = 67.6 [5.7-9,196.6]) than for auto-Abs neutralizing IFN-. only (OR [95% CI] = 2.6 [1.2-5.3]). ORs were also higher for auto-Abs neutralizing high concentrations (OR [95% CI] = 12.9 [4.6-35.9]) than for those neutralizing low concentrations (OR [95% CI] = 5.5 [3.1-9.6]) of IFN-omega and/or IFN-alpha 2

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

The original version of this article unfortunately contained a mistake

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Public Libraries and Spaces of Micro Connection in the Intercultural City

Everyday spaces represent central platforms that provide opportunities for encounters marked by ethnic and cultural diversity, where transformations can be negotiated that rethink living together. The significance of these ‘third places’ has been extensively researched. Yet, some spaces such as public libraries continue to be largely overlooked by geographers. Public libraries also remain under-appreciated within wider society despite their obvious social functions. Central here is that public libraries can be understood as dynamic and ‘lived spaces’ that enable the emergence of transient connections and relationships. Such spaces are increasingly sparse within modern cities. This paper explores the potential of everyday spaces of encounter, specifically public libraries, to facilitate the unfolding of ‘light’ connections and relationships, nurturing more inclusive forms of urban togetherness and belonging in multi-ethnic societies and the significance that people attribute to these often mundane encounters and micro connections. In so doing, this paper combines findings from two research projects that investigate mixed or intercultural encounters in public libraries in Bremen (Germany) and Glasgow (Scotland)

The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

International audienceSignificance There is growing evidence that preexisting autoantibodies neutralizing type I interferons (IFNs) are strong determinants of life-threatening COVID-19 pneumonia. It is important to estimate their quantitative impact on COVID-19 mortality upon SARS-CoV-2 infection, by age and sex, as both the prevalence of these autoantibodies and the risk of COVID-19 death increase with age and are higher in men. Using an unvaccinated sample of 1,261 deceased patients and 34,159 individuals from the general population, we found that autoantibodies against type I IFNs strongly increased the SARS-CoV-2 infection fatality rate at all ages, in both men and women. Autoantibodies against type I IFNs are strong and common predictors of life-threatening COVID-19. Testing for these autoantibodies should be considered in the general population