93 research outputs found
International Guillain-Barré Syndrome Outcome Study (IGOS): protocol of a prospective observational cohort study on clinical and biological predictors of disease course and outcome in Guillain-Barré syndrome
- Author
- Bateman K.
- Chavada Govindsinh
- Cornblath D. R.
- Cornblath David R.
- Dardiotis E.
- Faber C. G.
- Feasby T. E.
- Gorson K. C.
- Gorson Kenneth C.
- Harbo T.
- Harbo Thomas
- Hartung H. P.
- Hartung H. P.
- Hartung Hans Peter
- Hughes R. A.C.
- Hughes Richard A.C.
- Illa I.
- Islam B.
- Islam Z.
- Jacobs B. C.
- Jacobs B. C.
- Jacobs B. C.
- Jacobs Bart C.
- Kusunoki S.
- Kusunoki S.
- Kusunoki Susumu
- Lehmann H. C.
- Mohammad Q. D.
- Nobile-Orazio E.
- Péréon Y.
- Reddel S. W.
- Reisin R. C.
- Roodbol J.
- Shahrizaila N.
- van den Berg B.
- van den Berg B.
- van den Berg Bianca
- van den Bergh P.
- van der Kooi A. J.
- van Dijk G. W.
- van Doorn P. A.
- van Doorn Pieter A.
- van Woerkom M.
- Verboon C.
- Verboon C.
- Verboon Christine
- Visser L. H.
- Wang Y. Z.
- Willison H. J.
- Willison Hugh J.
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2017
- Field of study
Guillain-Barré syndrome (GBS) is an acute polyradiculoneuropathy with a highly variable clinical presentation, course, and outcome. The factors that determine the clinical variation of GBS are poorly understood which complicates the care and treatment of individual patients. The protocol of the ongoing International GBS Outcome Study (IGOS), a prospective, observational, multi-centre cohort study that aims to identify the clinical and biological determinants and predictors of disease onset, subtype, course and outcome of GBS is presented here. Patients fulfilling the diagnostic criteria for GBS, regardless of age, disease severity, variant forms, or treatment, can participate if included within two weeks after onset of weakness. Information about demography, preceding infections, clinical features, diagnostic findings, treatment, course and outcome is collected. In addition, cerebrospinal fluid and serial blood samples for serum and DNA is collected at standard time points. The original aim was to include at least 1000 patients with a follow-up of 1-3 years. Data are collected via a web-based data entry system and stored anonymously. IGOS started in May 2012 and by January 2017 included more than 1400 participants from 143 active centres in 19 countries across 5 continents. The IGOS data/biobank is available for research projects conducted by expertise groups focusing on specific topics including epidemiology, diagnostic criteria, clinimetrics, electrophysiology, antecedent events, antibodies, genetics, prognostic modelling, treatment effects and long-term outcome of GBS. The IGOS will help to standardize the international collection of data and biosamples for future research of GBS. ClinicalTrials.gov Identifier: NCT01582763
Singular shell embedded into a cosmological model
- Author
- A. Corichi
- A. Einstein
- C. Barrabés
- C. J. S. Clark
- C. Klein
- C. Stornaido
- D. Ida
- D. Langlois
- E. Eriksen
- E. Schücking
- H. Sato
- J. S. Høye
- K. Maeda
- M. Castagnino
- M. Mars
- N. Sakai
- N. Sakai
- N. Van den Bergh
- Peter D. Rippis
- R. Gautreau
- R. Gautreau
- R. Gautreau
- R. Gautreau
- R. O. Aquilano
- S. K. Blau
- T. Doležel
- T. Shiromizu
- V. A. Berezin
- V. A. Berezin
- V. A. Berezin
- V. De La Cruz
- V. H. Hamity
- W. B. Bonnor
- W. Israel
- W. Israel
- W. Israel
- W. Kuchař
- Y. Yamanaka
- ø. Grø
- ø. Grø
- ø. Grø
- ø. Grø
- Øyvind Grøn
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 07/11/2003
- Field of study
We generalize Israel's formalism to cover singular shells embedded in a
non-vacuum Universe. That is, we deduce the relativistic equation of motion for
a thin shell embedded in a Schwarzschild/Friedmann-Lemaitre-Robertson-Walker
spacetime. Also, we review the embedding of a Schwarzschild mass into a
cosmological model using "curvature" coordinates and give solutions with
(Sch/FLRW) and without the embedded mass (FLRW).Comment: 25 pages, 2 figure
Benefits and Risks of Primary Treatments for High-risk Localized and Locally Advanced Prostate Cancer : An International Multidisciplinary Systematic Review
- Author
- Briers Erik
- Cornford Philip
- Cumberbatch Marcus G.
- De Santis Maria
- Dorff Tanya
- Fanti Stefano
- Fossati Nicola
- Gandaglia Giorgio
- Gillessen Silke
- Grummet Jeremy P.
- Henry Ann M.
- Jain Suneil
- Kelly Brian
- Konety Badrinath
- Lam Thomas B.L.
- Lardas Michael
- Liew Matthew
- Mason Malcolm D.
- Moris Lisa
- Mottet Nicolas
- Omar Muhammad Imran
- Pal Raj
- Rouvière Olivier
- Schoots Ivo G.
- Tilki Derya
- van den Bergh Roderick C.N.
- Van den Broeck Thomas
- van Der Kwast Theodorus H.
- van Der Poel Henk G.
- Wiegel Thomas
- Willemse Peter Paul M.
- Yuan Cathy Y.
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2020
- Field of study
Copyright © 2020 European Association of Urology. Published by Elsevier B.V. All rights reserved.Peer reviewedPostprin
β -delayed fission and α decay of 196At
- Author
- Andel B.
- Andreyev A. N.
- Antalic S.
- Barzakh A.
- Capponi L.
- Cocolios T. E.
- De Witte H.
- Derkx X.
- Elseviers J.
- Fedorov D. V.
- Fedosseev V. N.
- Ghys L.
- Hessberger Fritz-Peter
- Huyse M.
- Kalaninová Z.
- Köster U.
- Lane J. F. W.
- Liberati V.
- Lynch K. M.
- Marsh B. A.
- Mitsuoka S.
- Nagame Y.
- Nishio K.
- Ota S.
- Pauwels D.
- Popescu L.
- Radulov D.
- Rapisarda E.
- Rothe S.
- Sandhu K.
- Seliverstov M. D.
- Sels S.
- Sjödin A. M.
- Truesdale V. L.
- Van Beveren C.
- Van den Bergh P.
- Van Duppen P.
- Wakabayashi Y.
- Publication venue
- Inst.
- Publication date
- 01/01/2016
- Field of study
Track E Implementation Science, Health Systems and Economics
- Author
- Abolarin O.
- Ackers M.
- Ackers M.
- Adouko S.
- Adungosi J.
- Afolayan F.
- Aghokeng A.
- Agot K.
- Ahimbisibwe A.
- Ahmed Y.
- Akwei Addo N.
- Alary M.
- Alexander G.
- Ali S.A.
- Allman D.
- Alumando E.S.
- Alves J.
- Amanyire G.
- Amenyah R.
- Angela A.
- Anthony G.
- Anthony J.
- Ardura Garcia C.
- Arrighi Y.
- Asante F.
- Asante K.
- Ashigbie P.
- Assouan I.
- Atibu J.
- Atuahene K.
- Avafia T.
- Avalos A.
- Ayieko B.
- Ayuaya T.
- Babu R.
- Barros H.
- Barry M.
- Behets F.
- Bertrand J.
- Bertrand J.
- Bhardwaj K.
- Bhende A.
- Bilguissa D.
- Birdthistle I.
- Birger R.
- Black D.
- Bogart L.
- Bogg L.
- Bollinger T.
- Bor J.
- Bor J.
- Boulet P.
- Boyer S.
- Brink B.
- Brockington S.
- Buhendwa L.
- Burrone E.
- Byonanebye D.
- Bärnighausen T.
- Bärnighausen T.
- Bärnighausen T.
- Carrieri M.P.
- Castor D.
- Castor D.
- Chabikuli O.
- Chadambuka A.
- Chamie G.
- Chamie G.
- Chamie G.
- Chandisarewa W.
- Chandrashekar S.
- Charlebois E.
- Charlebois E.
- Charlebois E.D.
- Chasela C.S.
- Chavez J.
- Cheng X.
- Chetty S.
- Chidarikire T.
- Chikwinya B.
- Chileshe C.
- Chimbindi N.Z.
- Chipimo M.
- Chisoko C.
- Churchman E.
- Churchyard G.
- Ciccacci F.
- Clark T.
- Clark T.
- Clark T.
- Cockburn J.
- Cohn J.
- Coleman S.
- Cornier N.
- Cummiskey C.
- Dagunduro T.
- Damisoni H.
- Dancel E.
- Davidovich U.
- De Costa A.
- Delaporte E.
- Des Jarlais D.C.
- Desinor O.
- Dhaliwal M.
- Dilorenzo M.A.
- Diseko L.
- Ditmore M.
- Dixon M.
- Dongmo Nguimfack B.
- Dorman S.
- Doumbouya B.
- Dowdy D.
- Drain P.
- Dringus S.
- Dryden‐peterson S.
- Dutta A.
- Edmonds A.
- Egger M.
- Ehmer J.
- El‐adas A.
- Escaleira F.
- Evi J.B.
- Fahim S.K.
- Fatti G.
- Feinstein L.
- Feldacker C.
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- Fennema H.
- Ferreyra C.
- Fidler S.
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- Formson C.
- Forsythe S.
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- Frade S.
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- Francis Munjattu J.
- Freedberg K.
- Freedberg K.A.
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- Freeman A.
- Fulwood Wood A.
- Gadisa T.
- Gaikwad D.S.S.
- Geng E.
- Geng E.
- Geng E.
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- Germano P.
- Gervas S.
- Ghosh S.C.
- Gibb D.M.
- Gichanga B.
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- Guidotti G.
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- Guthrie T.
- Gwarzo U.
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- Hamangaba F.
- Harris J.
- Hasselberg E.
- Hatwiinda S.
- Havlir D.
- Havlir D.V.
- Havlir D.V.
- Hayes R.
- Hemingway‐foday J.
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- Herbst A.J.
- Hering H.
- Hijazi M.
- Hill A.
- Hodder S.
- Holtgrave D.
- Hosseinipour M.
- Hosseinipour M.C.
- Hounkanrin G.
- Hugar V.
- Ibrahim I.M.
- Idele P.
- Ilnitski A.
- Ingrid B.
- Isavwa A.
- Isa‐dutse S.
- Jain V.
- Jain V.
- Jain V.
- Jamieson D.J.
- Jani I.
- Jaramillo L.
- Johnson D.
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- Kabami J.
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- Kamya M.
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- Kargbo B.
- Kasedde S.
- Katz I.
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- Khoshnood K.
- Kimuli R.
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- Kioko U.
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- Kiwango J.
- Kizito H.
- Knight L.
- Kohler J.
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- Konstantinov B.
- Kouanfack C.
- Koulla‐shiro S.
- Kwarisiima D.
- Kwarisiima D.
- Kwarisiima D.
- Labhardt N.D.
- Laborde‐balen G.
- Lates J.
- Laurent C.
- Lehe J.
- Lewis T.
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- Lockman S.
- Loolpapit M.
- Loolpapit M.
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- Lu F.
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- Mabirizi D.
- Machaku M.
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- Maggard K.
- Magure D.T.
- Mahapatra B.
- Mahomva A.
- Maji T.
- Makani V.
- Makoane C.
- Makonnen M.
- Makunike ‐chikwinya B.
- Makwelebi V.
- Mamo Y.
- Manabe Y.
- Manenji A.
- Mansinho K.
- Marazzi M.C.
- March L.
- Marino P.
- Mattanovich D.
- Mavhu W.
- Mavhu W.
- Mavise G.
- Mbengashe T.
- Mbuya V.
- Mbwolie Nsabala H.
- McGowan G.
- Mehta S.
- Melaku Z.
- Melkamu Y.
- Mensah‐maïka B.
- Menzies N.
- Merry C.
- Meyer‐rath G.
- Mgugu D.
- Middleton‐lee S.
- Milani B.
- Miller C.
- Mine M.
- Miruka F.
- Miruka F.
- Mmalane M.
- Moatti J.‐p.
- Moatti J.‐p.
- Mohlaba M.
- Mokone M.
- Mondal S.
- Montaner J.
- Moon S.
- Morse J.
- Moss W.J.
- Motshegwa P.
- Moyo S.
- Mpoudi‐ngole E.
- Muchedzi A.
- Mueller O.
- Mugume A.
- Muhamadi L.
- Muirhead D.
- Mukumbi H.
- Mulema V.S.
- Mulenga E.
- Mulenga Y.
- Mumbe L.
- Murugan S.K.
- Muttai H.
- Muttai H.
- Mwamba B.
- Mwepu C.
- Mwila L.
- Naduta G.
- Nakamura Y.M.
- Nalli A.
- Ndagano D.
- Ndebele W.
- Ndlovu M.
- Neuhann H.W.F.
- Nevhutalu Z.
- Newell M.‐l.
- Newell M.‐l.
- Newell M.‐l.
- Newman J.
- Nganga L.
- Nguyen L.
- Nguyen T.Q.
- Nidhi G.
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- Njeuhmeli E.
- Njeuhmeli E.
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- Noubary F.
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- Nwuba C.O.
- Nyabela M.
- Nyathi M.
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- Ogo I.
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- Okonji J.
- Omanga E.
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- Orlando S.
- Osika J.
- Oyebanji O.
- O’Briain W.
- O’Malley J.
- Paik E.
- Pal A.
- Palchaudhuri S.
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- Paltiel A.D.
- Paltiel A.D.
- Panessa C.
- Park C.
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- Putsoane M.
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- Ross D.
- Rowe W.‐a.
- Rusakaniko S.
- Ryan M.
- Sabapathy K.
- Sagaon Teyssier L.
- Sagwa E.
- Saint‐sauveur J.f.
- Samungole G.
- Satish S.
- Savosnick P.
- Sawyer W.
- Sax P.E.
- Schackman B.R.
- Scheibe F.J.B.
- Schilperoord M.
- Sculpher M.
- Segaren N.
- Segaren N.
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- Tanser F.
- Taziwa F.
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- Thirumurthy H.
- Thirumurthy H.
- Thirumurthy H.
- Thompson D.
- Tiam A.
- Tirumalasetti V.R.
- Tobaiwa O.
- Toki D.
- Topp S.
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- Touré S.
- Tsoeu M.
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- Turnbull E.
- Tweya H.
- Tweya H.
- Umenyi C.
- Van den Bergh R.
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- van der Horst C.
- van Dijk J.H.
- van Widenfelt E.
- van Zyl A.
- Vassal A.
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- Vickerman P.
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- Waiswa P.
- Walensky R.
- Walensky R.P.
- Walensky R.P.
- Walker S.
- Wallace N.
- Wandeler G.
- Wanjiku L.
- Watts C.
- Watts C.
- Weigel R.
- Weinstein M.C.
- Weir B.W.
- Whiddon L.
- Wolde A.
- Wondergem P.
- Wong W.
- Wu Z.
- Xiong K.
- Yankah E.
- Yazdanpanah Y.
- Yekeye R.
- Yiweza Tshipala D.
- Zaho M.
- Zeh C.
- Zeng G.
- Zewdu S.
- Zhyhinas O.
- Zuure F.
- ’t Hoen E.
- Publication venue
- 'International AIDS Society'
- Publication date
- 01/10/2012
- Field of study
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138412/1/jia218443.pd
Crowdsourcing hypothesis tests: Making transparent how design choices shape research results
- Author
- Aaron L Wichman (7870478)
- Adam Hahn (5854712)
- Adam W Craig (7870274)
- Albert L Ly (7870370)
- Alejandro Vásquez-Echeverría (7870469)
- Alexander F Danvers (7870280)
- Alexander Ly (3563606)
- Alice Dominici (7870292)
- Alycia Chin (7319771)
- Ambra Brizi (468832)
- Andree Hartanto (7870313)
- Andrei Cimpian (2551444)
- Andres Montealegre (6690119)
- Andrew C Hafenbrack (7870307)
- Andrew Jones (18254)
- Andrew Proctor (1639873)
- Anna Dreber (260608)
- Anna Fung (7870301)
- Anna Szabelska (7870460)
- Anthony Lantian (7870346)
- Astrid Schütz (2635561)
- Aurélien Allard (7870223)
- Bastian Jaeger (5024882)
- Benjamin Y Cheung (7870262)
- Benoît Monin (5619653)
- Bettina von Helversen (406585)
- Bradley J Baker (7870232)
- Brett G Mercier (7870385)
- Brett Raymond-Barker (7870424)
- Caleb J Reynolds (7870430)
- Carmel A Levitan (7870364)
- Casper J Albers (7870220)
- Charles R Ebersole (7870157)
- Christina M Tworek (7870199)
- Christopher R Madan (7870376)
- Christopher W Bauman (7870169)
- Conrad A Corretti (7870271)
- Corinna Michels (7870388)
- Daniel M Bartels (7870166)
- Daniel Storage (2551447)
- Daniel Walco (7870205)
- Danka B Purić (7870421)
- David E Redman (7870427)
- David J Johnson (7870184)
- Desmond W Leung (7870361)
- Diego A Reinero (7870193)
- Domenico Viganola (7870151)
- Don van den Bergh (5531045)
- Elizabeth Mullen (7003085)
- Eric L Stocks (7870451)
- Eric L Uhlmann (7870331)
- Eric-Jan Wagenmakers (1747534)
- Erica D Musser (7870394)
- Erik Dietl (5781083)
- Ernest Baskin (4853899)
- Eugene Y Chan (7870259)
- Felix Cheung (7870175)
- Felix Holzmeister (4804356)
- Florian Brühlmann (7743914)
- Francesco Pellegrini (7870409)
- Gabriel Baník (7870235)
- Garrett L Strosser (7870454)
- Gerit Pfuhl (5006987)
- Gustav Nilsonne (258802)
- Hannah Perfecto (6077156)
- Harry Manley (516006)
- Hause Lin (6247806)
- Hendrik Bruns (7870250)
- Ian A Anderson (7870226)
- Ian GJ Dawson (7870283)
- Ian Hussey (7870328)
- Iris Žeželj (7870484)
- Isabel L Ding (7870148)
- Ivan Ropovik (7870433)
- Jais Troian (7870466)
- James M Leonhardt (7870358)
- Jamie S Song (7870502)
- Jan K Woike (7870481)
- Janis H Zickfeld (7870487)
- Janna K Ruessmann (7870439)
- Jay J Van Bavel (7870202)
- Jean-François Campourcy (7870256)
- Jennifer Ray (7870190)
- Jesse Reynolds (5162855)
- Joachim Hüffmeier (5234282)
- Joel Blanke (7870244)
- Johannes Breuer (3238932)
- Johannes T Doerflinger (7870289)
- John E Edlund (7870298)
- Jonathan Leclerc (7870355)
- Jonathon McPhetres (6013958)
- Jordan W Suchow (7870457)
- Joseph Hilgard (3333711)
- Joseph P Heffner (7870319)
- Jozef Bavolar (7870238)
- Julian Wills (7870208)
- Jun Pang (591243)
- Justin F Landy (7870142)
- Justin P Laplante (7870349)
- Kai Chi Yam (7870211)
- Kenneth D Locke (7870367)
- Kian Siong Tey (7870463)
- Kit W Cho (7870265)
- Koen Derks (7870163)
- Konrad Jamro (7870334)
- Kurt J Schuepfer (7870448)
- Lacy E Krueger (7870343)
- Ladislas Nalborczyk (6570560)
- Leigh Ann Vaughn (7870472)
- Leigh Caldwell (7870253)
- Leonid Tiokhin (6324269)
- Ljiljana B Lazarevic (7870352)
- Lorenz Graf-Vlachy (7158953)
- Lucas Keller (7870340)
- Lukas Röseler (7870436)
- Lynn Wong (7870508)
- M Brent Donnellan (7870178)
- Maarten Marsman (3563609)
- Magnus Johannesson (123135)
- Marcel Martončik (7870379)
- Marco Tullio Liuzza (7358387)
- Mariola Paruzel-Czachura (7870406)
- Mark H Phillips (7870415)
- Mark Verschoor (6117188)
- Martin Schweinsberg (3704101)
- Martin V Day (7870286)
- Matthew Fisher (167773)
- Matthew H Goldberg (7870304)
- Matthias Stefan (4804359)
- Matúš Adamkovič (7870217)
- Maura Pozzi (5906831)
- May-Anne Very (7870505)
- Melanie MacEacheron (7870373)
- Miaolei Liam Jia (7870145)
- Michael C Mullarkey (7870391)
- Michael P Hall (7870181)
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- Xi Kang (1547992)
- Xiaobing Xu (678014)
- Xiaoyu Yang (547580)
- Yen-Ping Chang (7348763)
- Yeonsin Ahn (7870490)
- Yoo Jin Lee (489567)
- Publication venue
- Publication date
- 15/11/2019
- Field of study
To what extent are research results influenced by subjective decisions that scientists make as they design studies? Fifteen research teams independently designed studies to answer fiveoriginal research questions related to moral judgments, negotiations, and implicit cognition. Participants from two separate large samples (total N > 15,000) were then randomly assigned to complete one version of each study. Effect sizes varied dramatically across different sets of materials designed to test the same hypothesis: materials from different teams renderedstatistically significant effects in opposite directions for four out of five hypotheses, with the narrowest range in estimates being d = -0.37 to +0.26. Meta-analysis and a Bayesian perspective on the results revealed overall support for two hypotheses, and a lack of support for three hypotheses. Overall, practically none of the variability in effect sizes was attributable to the skill of the research team in designing materials, while considerable variability was attributable to the hypothesis being tested. In a forecasting survey, predictions of other scientists were significantly correlated with study results, both across and within hypotheses. Crowdsourced testing of research hypotheses helps reveal the true consistency of empirical support for a scientific claim.</div
New insights into the genetic etiology of Alzheimer's disease and related dementias
- Author
- Aaltonen L.
- Aaltonen V.
- Aarsland Dag
- Aavikko M.
- Abalos M.S.
- Abdelnour Carla
- Abner E.
- Abraham R.
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- Adarmes-Gómez A.
- Adarmes-Gómez A.D.
- Aguilera N.
- Aguilera N.
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- Ahmad S.
- Akinyemi R.O.
- Al-Chalabi A.
- Alarcón-Martín Emilio
- Albert M.S.
- Albin R.L.
- Alcolea Daniel
- Alegret Montserrat
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- Publication venue
- Publication date
- 01/01/2022
- Field of study
Characterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/'proxy' AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE ε4 allele
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
- Author
- Abbas Rezaianzadeh
- Abdonas Tamosiunas
- Abdul Basit
- Abdul Hamid Zargar
- Abdullah Alkandari
- Abdullatif Husseini
- Abhijit Sen
- Abla M Sibai
- Abu Am Hanif
- Adela Chirita-Emandi
- Adelheid Weber
- Adetoyeje Y Oyeyemi
- Adewale L Oyeyemi
- Adolfo Rubinstein
- Adoubi Kassi Anicet
- Adroaldo Cesar Araujo Gaya
- Afshin Ostovar
- Agnes L Kadvan
- Agneta Sjöberg
- Agneta Yngve
- Agnès Le Port
- Agustinus Soemantri
- Agustín Perez-Londoño
- Ahmad A Zainuddin
- Ahmad Faudzi Yusoff
- Ahmad Reza Dorosty
- Ahmed A Madar
- Aida Pilav
- Aïcha Soumaré
- Akaninyene Otu
- Akihiro Yoshihara
- Akkumis Salhanova
- Akram Pourshams
- Ala'a Alkerwi
- Alain Morejon
- Alanna G da Silva
- Albertino Damasceno
- Alberto Barceló
- Alberto Palloni
- Albina A Fakhretdinova
- Alejandro Diaz
- Aleksander Giwercman
- Aleksandra Gomula
- Aleksandra Piwonska
- Alessandro Gialluisi
- Aletta E Schutte
- Alexander D Deev
- Alexandra M Cucu
- Alexandre C Pereira
- Alfonso Siani
- Alfonso Sousa-Poza
- Ali Ahmadi
- Ali Akbar Shayesteh
- Ali Esmaeili
- Ali Ghanbari
- Ali Reza Safarpour
- Alice Bonilla-Vargas
- Alicia Matijasevich
- Alina G Platonova
- Alina Kerimkulova
- Aline Meirhaeghe
- Aline P Batista
- Alireza Ansari-Moghaddam
- Alireza Khosravi
- Alireza Moslem
- Alireza Sadjadi
- Alisha N Wade
- Alison J Hayes
- Alison J Price
- Allan G Hill
- Allan Linneberg
- Almaz Sharman
- Altan Onat
- Aluisio Jd Barros
- Alun Evans
- Amalia De Curtis
- Amanda G Thrift
- Amanda J Cross
- Amaneh Shayanrad
- Ambady Ramachandran
- Amelia C Crampin
- Amina Barkat
- Amir Houshang Mehrparvar
- Amirabbas Momenan
- Ana Azevedo
- Ana B Crujeiras
- Ana Barradas-Pires
- Ana Carolina Mgn de Sá
- Ana D González-Alvarez
- Ana Henriques
- Ana I Rito
- Ana Jelaković
- Ana Maria B Menezes
- Ana P Ortiz
- Ana Paula C Cândido
- Anabela Mota-Pinto
- Anar Dushpanova
- Anastasia Markaki
- Anders Grøntved
- Andre L Guimaraes
- Andre P Kengne
- Andrea Gazzinelli
- Andrea Gualtieri
- Andrea Rodriguez-Martinez
- Andrea Rvr Horimoto
- Andrea Schneider
- Andrea Y Rodríguez
- Andrea Zentai
- Andreas Stang
- Andreia N Pizarro
- Andrew Kingston
- Andrew Reynolds
- Andrew Wong
- Andrzej Galbarczyk
- Andrzej Pająk
- Andrzej Więcek
- Anelise Reis Gaya
- Aneta Grajda
- Aneta Weres
- Anette Varbo
- Angel R Gonzalez
- Angela Chetrit
- Angela Döring
- Angela Spinelli
- Angelika Schaffrath Rosario
- Angelique Chan
- Angélica M Ochoa-Avilés
- Anie Marcil
- Anil Poudyal
- Anja L Madsen
- Anja Schienkiewitz
- Anna Bartosiewicz
- Anna Bugge
- Anna Fijalkowska
- Anna Jansson
- Anna V Alieva
- Annamari Lundqvist
- Anne A Bjerregaard
- Anne Chinnock
- Anne Juolevi
- Anne Taylor
- Anne Tjonneland
- Anneke Blokstra
- Annette J Dobson
- Annette Peters
- Annika Rosengren
- Anthony Kafatos
- Antonia Trichopoulou
- Antonio Bernabe-Ortiz
- Antonio Cabrera de León
- Antonio M Silva
- Antonio Mistretta
- Antonio Pedro Graça
- Antonio Prista
- Antonis Zampelas
- Antonisamy Belavendra
- Anu Mishra
- Anwar M Batieha
- Archie W Rayner
- Areti Triantafyllou
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- Baltazar Nunes
- Barbara Heude
- Barbara Thorand
- Barry M Popkin
- Batyrbek Assembekov
- Beatriz D Schaan
- Bee Koon Poh
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- Bekbolat Zholdin
- Belgin Unal
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- Ben Schöttker
- Benjamin Acosta-Cazares
- Benoit Salanave
- Benson M Kazembe
- Bente Sparboe-Nilsen
- Bernard Maire
- Bernardo L Horta
- Bernhard O Boehm
- Bert-Jan van den Born
- Bettina Bringolf-Isler
- Bharathi Viswanathan
- Bhawesh Koirala
- Bihungum Bista
- Bill Stavreski
- Bin Zhou
- Bing Zhang
- Birgit Linkohr
- Biruta Velika
- Blanca Sandra Ruiz-Betancourt
- Bo Werner
- Boban Mugoša
- Bogdan Wojtyniak
- Bojan Jelaković
- Bontha V Babu
- Boyd A Swinburn
- Börge Schmidt
- Branimir Leskošek
- Breige A McNulty
- Brian Oldenburg
- Brooklyn Fraser
- Bruna Gonçalves Cordeiro da Silva
- Buthaina M Alkhatib
- Børge G Nordestgaard
- Caleb Ochimana
- Calogero Saieva
- Calvin Ke
- Camilla T Damsgaard
- Carl Lachat
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- Carlo Maria Barbagallo
- Carlos A Aguilar-Salinas
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- Carmen Iñiguez
- Carolina B Tarqui-Mamani
- Caroline H Fall
- Caroline Ramos de Moura Silva
- Carsten O Schmidt
- Cassiano Ricardo Rech
- Catherine Kyobutungi
- Catterina Ferreccio
- Cecilia Björkelund
- Cecily Kelleher
- Cesar G Victora
- Cézane P Reuter
- Chandini Nekkantti
- Chao Qiang Jiang
- Charalambos A Hadjigeorgiou
- Charles Agyemang
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- Charlie Lim
- Charlotte B Ottendahl
- Charmaine A Duante
- Charumathi Sabanayagam
- Chiara Donfrancesco
- Chien-An Sun
- Chien-Jen Chen
- Ching-Yu Cheng
- Chinh Nguyen Huu
- Chinwuba Ijoma
- Chongjian Wang
- Chris Cowell
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- Christian Gieger
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- Christine Cameron
- Christophe Tzourio
- Christopher J Paciorek
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- Cláudia S Minderico
- Clicerio González-Villalpando
- Clive Osmond
- Coimbatore Subramaniam Shanthirani
- Con Burns
- Constance Schultsz
- Constanta Huidumac Petrescu
- Cora L Craig
- Correia Júnior Marco Aurélio de Valois
- Cosmin R Cojocaru
- Cristina P Padez
- Crizian G Saar
- Cynthia M Pérez
- Cyrus Cooper
- Daan Kromhout
- Dalia Luksiene
- Damaskini Valvi
- Damian K Francis
- Dan Zhu
- Daniel Bia
- Daniel Fernández-Bergés
- Daniel Ferrante
- Daniel G Vasques
- Daniel Lemogoum
- Daniel Weghuber
- Daniela Galeone
- Daniela Kállayová
- Daniela Pierannunzio
- Daniela Rodrigues
- Daphne Lai
- Daphne Mirkopoulou
- David A Gonzalez-Chica
- David De Ridder
- David Faeh
- David Goltzman
- Davide Noto
- Davood Khalili
- Deborah C Malta
- Debra S Judge
- Deena Al Asfoor
- Deepak N Amarapurkar
- Delphine De Smedt
- Demetre Labadarios
- Denise Eldemire-Shearer
- Dermot O'Reilly
- Dénes Molnár
- Diana A Santos
- Diane T Meto
- Dianna J Magliano
- Dickman Gareta
- Diego Augusto Santos Silva
- Diego G Christofaro
- Diego Salmerón
- Diego Vanuzzo
- Dimitrios Papandreou
- Dimitrios Poulimeneas
- Dimitrios Trichopoulos
- Dirk De Bacquer
- Dirk Vanderschueren
- Dominique Cottel
- Dominique Hange
- Dong Zhao
- Dongfeng Gu
- Dora Romaguera
- Doris Stöckl
- Dorja Vocanec
- Doroteia A Höfelmann
- Dusko J Bjelica
- Dušan Grafnetter
- Duygu Islek
- Dwi Hapsari Tjandrarini
- E Shyong Tai
- Ebrahim Eftekhar
- Ebrahim Ghaderi
- Eduardo Capuano
- Eduardo Salazar Martinez
- Edward F Fottrell
- Edward Janus
- Edward W Gregg
- Edwige Landais
- Edyta Łuszczki
- Eero O Kajantie
- Efthymios Kapantais
- Eha Nurk
- Ei Ei K Nang
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- Ekaterina Chikova-Iscener
- Ekaterina Stoyanova
- Elaine Dennison
- Elaine M Murtagh
- Eldridge Ferrer
- Elena Anufrieva
- Elena Bogova
- Elena Pahomova
- Elena Sacchini
- Elena V Skoblina
- Eleonora d'Orsi
- Elias F Gudmundsson
- Elin Kolle
- Elin P Sørgjerd
- Elio Riboli
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- Else Karin Grøholt
- Elvis Oa Wambiya
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- Elysée Claude Bika Lele
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- Eman Aly
- Emanuel Zitt
- Emanuela Gualdi-Russo
- Emanuela Pettenuzzo
- Emiel Hoogendijk
- Emily B Wong
- Emily Sonestedt
- Emma Ruiz Moreno
- Emmanuel Cohen
- Emmanuella Magriplis
- Eng Joo Tan
- Enguerran Macia
- Enisa Kujundzic
- Enrique Gutiérrez González
- Enzo Manzato
- Erfan Ghasemi
- Eric Monterrubio-Flores
- Erik J Timmermans
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- Erkin Mirrakhimov
- Ertugrul Celikcan
- Eruke E Egbagbe
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- Esteban Carmuega
- Esther Lopez-Garcia
- Esther M González-Gil
- Ethel Santacruz
- Eugène Sobngwi
- Eunice Ugel
- Eva Corpeleijn
- Eva Gerdts
- Eva Karaglani
- Eva Martos
- Evangelia Tzala
- Ewelina Czenczek-Lewandowska
- Éva Kovács
- Fabian Rohner
- Fabián Méndez
- Fabio Galvano
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- Farahnaz Joukar
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- Farid Najafi
- Farshad Farzadfar
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- Fatai A Maruf
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- Felicia Cañete
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- Fereidoun Azizi
- Fernanda Cunha Soares
- Fernando Rigo
- Fernando Rodríguez-Artalejo
- Félicité Tchibindat
- Fikru Tullu
- Flavio D Fuchs
- Flavio Nervi
- Flora Am Ukoli
- Flora Bacopoulou
- Florian Muca
- Francesco Branca
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- Francisco de Assis Guedes de Vasconcelos
- Francisco J Felix-Redondo
- François F Kaze
- Frank Claessens
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- Gilda Estela Benitez Rolandi
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- Gulmira Aitmurzaeva
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- Stefan Söderberg
- Stefania Maggi
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- Stefano Marventano
- Steinar Krokstad
- Stephen T McGarvey
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- Takafumi Ishida
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- Wan Nazaimoon Wan Mohamud
- Wei Zheng
- Wei-Cheng Lo
- Wei-Yen Lim
- Weili Yan
- Wen-Harn Pan
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- Wendy Van Lippevelde
- Wenhua Zhao
- Wichai Aekplakorn
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- Wojciech Drygas
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- Wolfgang Ahrens
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- Xiangjun Wang
- Xiaoguang Yang
- Xiaotian Liu
- Ximena Berrios Carrasola
- Xinyi Gwee
- Xiu-Hua Guo
- Xu Lin
- Xu Ma
- Xueling Sim
- Xun Tang
- Ya Xing Wang
- Yadlapalli S Kusuma
- Yajaira Briceño
- Yang Yang
- Yanhui Dong
- Yanina Zocalo
- Yanitsa V Zhecheva
- Yannis Manios
- Yanping Li
- Yemane Berhane
- Yeunsook Rho
- Yeva Movsesyan
- Yi Song
- Yi Zeng
- Yih Chung Tham
- Yiling J Cheng
- Yin Guo
- Ying-Wei Wang
- Yingfeng Zheng
- Yn-Tz Sung
- Yong Tao
- Yonghua Hu
- Yosef Farzi
- Yoto Yotov
- Youcef Laid
- Young-Ho Khang
- Yousef Saleh Khader
- Yu-Ling Yu
- Yuan He
- Yufang Bi
- Yuki Fujita
- Yulia Balanova
- Yuliya V Solovieva
- Yuna He
- Yunjiang Yu
- Yury P Nikitin
- Yves Kameli
- Yves Martin-Prevel
- Yvonne T van der Schouw
- Zahra Mohammadi
- Zbigniew Gaciong
- Zbigniew Kulaga
- Zengchang Pang
- Zhamilya Battakova
- Zhamyila Usupova
- Zhanna Kalmatayeva
- Zhen-Yu Zhang
- Zhengming Chen
- Ziad A Abdeen
- Zivka Dika
- Zlatko Fras
- Zulfiqar A Bhutta
- Zulfiya Abdurrahmonova
- Zumin Shi
- Łukasz Kryst
- Publication venue
- Publication date
- 01/03/2024
- Field of study
Background Underweight and obesity are associated with adverse health outcomes throughout the life course. We
estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from
1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories.
Methods We used data from 3663 population-based studies with 222 million participants that measured height and
weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate
trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children
and adolescents (age 5–19 years), from 1990 to 2022 for 200 countries and territories. For adults, we report the
individual and combined prevalence of underweight (BMI <18·5 kg/m2) and obesity (BMI ≥30 kg/m2). For schoolaged children and adolescents, we report thinness (BMI <2 SD below the median of the WHO growth reference)
and obesity (BMI >2 SD above the median).
Findings From 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in
11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed
changes were true decreases. The combined prevalence increased in 162 countries (81%) for women and
140 countries (70%) for men with a posterior probability of at least 0·80. In 2022, the combined prevalence of
underweight and obesity was highest in island nations in the Caribbean and Polynesia and Micronesia, and
countries in the Middle East and north Africa. Obesity prevalence was higher than underweight with posterior
probability of at least 0·80 in 177 countries (89%) for women and 145 (73%) for men in 2022, whereas the converse
was true in 16 countries (8%) for women, and 39 (20%) for men. From 1990 to 2022, the combined prevalence of
thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a
posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%)
with a posterior probability of at least 0·80. The countries with highest combined prevalence of thinness and
obesity in school-aged children and adolescents in 2022 were in Polynesia and Micronesia and the Caribbean for
both sexes, and Chile and Qatar for boys. Combined prevalence was also high in some countries in south Asia, such
as India and Pakistan, where thinness remained prevalent despite having declined. In 2022, obesity in school-aged
children and adolescents was more prevalent than thinness with a posterior probability of at least 0·80 among girls
in 133 countries (67%) and boys in 125 countries (63%), whereas the converse was true in 35 countries (18%) and
42 countries (21%), respectively. In almost all countries for both adults and school-aged children and adolescents,
the increases in double burden were driven by increases in obesity, and decreases in double burden by declining
underweight or thinness.
Interpretation The combined burden of underweight and obesity has increased in most countries, driven by an
increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. A healthy
nutrition transition that enhances access to nutritious foods is needed to address the remaining burden of
underweight while curbing and reversing the increase in obesit
Synthesis of the elements in stars: forty years of progress
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Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity
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- Alcolea Daniel
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The IPDGC (The International Parkinson Disease Genomics Consortium) and EADB (Alzheimer Disease European DNA biobank) are listed correctly as an author to the article, however, they were incorrectly listed more than once
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