‘“An Octoroon in the Kindling”: American Vernacular & Blackface Minstrelsy in 1930s Hollywood.’

For close on to a hundred years discourses on national identity, European ethnic assimilation and the problem of class division within the Republic had been principally addressed in the popular arts through the agency of the black mask. During the 1930s, blackface in American films shifted from the idea implied in the racial slur, “nigger in the woodpile,” to the rather less visible, but no less derogatory, “octoroon in the kindling,” a phrase used in Her Man (Pathé, Tay Garnett, 1930) to suggest something is amiss, but which is used here to suggest the cultural miscegenation that informs much of the material discussed in this article.</jats:p

Senior Recital: Dirk Stanfield, flute

This recital is presented in partial fulfillment of requirements for the degree Bachelor of Music in Performance. Mr. Stanfield studies flute with Christina Smith.https://digitalcommons.kennesaw.edu/musicprograms/1508/thumbnail.jp

The Who and Pop Art: the simple things you see are all complicated

The essay investigates the connections between The Who and Pop Art. It uses Lawrence Alloway’s expansive concept of Pop Art, which he defines as a correspondence along a continuum between the commercial and the fine arts. The Who, I argue, exemplify this process of connectivity between the low and the high. The analysis focuses on the contradiction in the received wisdom that the band did little more than willfully exploit Pop Art imagery and the counter-idea that they were significant innovators within a form that had otherwise become limited in scope and ambition. Key questions are asked about authenticity and appropriation, race and pop, and art and sonic dissonance. The central object of the enquiry is the band’s debut album, My Generation, and a handful of 45s released in 1965-66

An Exploration of Place-Based TESOL

The purpose of this study is to explore the assumption that classrooms are the most appropriate places for the Teaching of English as a Second or Other Language (TESOL) to adult learners in contemporary global society. It considers the success of postmodern general education curricula that systematically dissolve the boundaries between the classroom and the community and seeks to show why such a place-based approach might be particularly useful in transforming TESOL curricula which for the most part overlook informal learning. This study offers 15 successful non-mother tongue English users the opportunity to reflect on their language learning in two separate open-ended interviews. Subsequently, it analyses the range and properties of the places of their acquisition as they emerge from the interview data. The study finds that the classroom is an insufficient place because its social relations necessarily limit learner agency and generally render it ineffective for ESOL acquisition. This suggests the need to transform TESOL into a practice from within which quite new places of learning with more equal social relations emerge where English language can be effectively acquired. This study recommends that English language learners and teachers collaboratively negotiate opportunities for participation in real-world English speaking communities of practice in order to acquire language rapidly and thoroughly. It suggests that this might be achieved by transforming tertiary level English classrooms into laboratories for critical reflection where students are encouraged to discuss problems of significance to them and subsequently deliver real world solutions to the local community. This exploration of place-based TESOL employs Critical Discourse Analysis as its methodology and is situated within the critical paradigm of language education research.The University of Exete

Do ethnic differences in cord blood leptin levels differ by birthweight category? Findings from the Born in Bradford cohort study.

BACKGROUND: There is evidence that South Asian individuals have higher fat mass for a given weight than Europeans. One study reported that the greater fatness for a given birthweight may increase with increasing birth weight, suggesting that any attempt to increase mean birth weight in South Asians would markedly increase their fatness. OBJECTIVE: Our objective was to examine whether differences in cord leptin values between White British and Pakistani infants vary by birth weight category. METHOD: We examined the difference in cord leptin levels between 659 White British and 823 Pakistani infants recruited to the Born in Bradford cohort study, by clinical categories and thirds of the birth weight distribution. RESULTS: Pakistani infants had a lower mean birthweight but higher cord leptin levels than White British infants [ratio of geometric mean(RGM) of cord leptin adjusted for birth weight = 1.36 (95% CI 1.26,1.46)]. Birthweight was positively associated with cord leptin levels in both groups, with no evidence that the regression lines in the two groups diverged from each other with increasing birthweight.The relative ethnic difference in cord leptin was similar in low (<2500 g), normal and high (≥4000 g) birthweight infants(P-value for interaction = 0.91). It was also similar across thirds of the birthweight distribution [RGM (95% CI) in lowest, mid and highest thirds were 1.37 (1.20, 1.57), 1.36 (1.20, 1.54) and 1.31 (1.16, 1.52), respectively, P-interaction = 0.51]. CONCLUSIONS: We found marked differences in cord leptin levels between Pakistani and White British infants but no evidence that this difference increases with increasing birthweight

Delinquent Daughters:Hollywood's war effort and the 'juvenile delinquency picture' cycle

This paper examines a short-lived cycle of ‘juvenile delinquency pictures’ that have been almost entirely ignored in scholarship on the teen film, perhaps in part because they focus on female rather than male youth. Whilst individually unremarkable, collectively these films were central to political debates about the role of Hollywood in wartime. This paper maps the widespread discursive struggles between Hollywood, the middlebrow press, industry regulators, and various government agencies over the production of this cycle. It moves on to analyse the New York reception of these films, highlighting how this ‘cycle of sensation’ was debated in relation to the very local contexts of New York's ‘bobby soxers’ and ‘victory girls’ and the strategies to police them in and around Times Square. It demonstrates that focusing on the localized and contested terrain of discourses surrounding historically situated media cycles reveals the complexity and local specificity required of micro-historical enquiry

Structures of the CCR5 N Terminus and of a Tyrosine-Sulfated Antibody with HIV-1 gp120 and CD4

The CCR5 co-receptor binds to the HIV-l gp120 envelope glycoprotein and facilitates HIV-l entry into cells. Its N terminus is tyrosine-sulfated, as are many antibodies that react with the co-receptor binding site on gp120. We applied nuclear magnetic resonance and crystallographic techniques to analyze the structure of the CCR5 N terminus and that of the tyrosine-sulfated antibody 412d in complex with gp120 and CD4. The conformations of tyrosine-sulfated regions of CCR5 (α-helix) and 412d (extendedloop) are surprisingly different. Nonetheless, a critical sulfotyrosine on CCR5 and on 412d induces similar structural rearrangements in gp120. These results now provide a framework for understanding HIV-l interactions with the CCR5 N terminus during viral entry and define a conserved site on gp120, whose recognition of sulfotyrosine engenders posttranslational mimicry by the immune system

Structures of the CCR5 N Terminus and of a Tyrosine-Sulfated Antibody with HIV-1 gp120 and CD4

The CCR5 co-receptor binds to the HIV-l gp120 envelope glycoprotein and facilitates HIV-l entry into cells. Its N terminus is tyrosine-sulfated, as are many antibodies that react with the co-receptor binding site on gp120. We applied nuclear magnetic resonance and crystallographic techniques to analyze the structure of the CCR5 N terminus and that of the tyrosine-sulfated antibody 412d in complex with gp120 and CD4. The conformations of tyrosine-sulfated regions of CCR5 (α-helix) and 412d (extendedloop) are surprisingly different. Nonetheless, a critical sulfotyrosine on CCR5 and on 412d induces similar structural rearrangements in gp120. These results now provide a framework for understanding HIV-l interactions with the CCR5 N terminus during viral entry and define a conserved site on gp120, whose recognition of sulfotyrosine engenders posttranslational mimicry by the immune system

Structural Integrity of the -Carboxyglutamic Acid Domain of Human Blood Coagulation Factor IXa Is Required for Its Binding to Cofactor VIIIa

This report describes the analysis of a novel mutant human factor IX protein from a patient with hemophilia B (factor IX activity adenine transition) in exon 2 at nucleotide 6409 which results in a glycine --> arginine substitution at amino acid 12 in the gamma-carboxyglutamic acid rich (Gla) domain of the mature protein. Factor IX was isolated by immunoaffinity chromatography from plasma obtained from the proband. The purified protein is indistinguishable from normal factor IX by polyacrylamide gel electrophoresis. Characterization of the variant in purified component assays reveals that it is activated normally by its physiologic activator factor XIa, but its phospholipid-dependent activation by the factor VIIa-tissue factor complex is diminished. In the presence of phospholipid and 5 mM Ca2+, the activities of variant and normal plasma-derived factor IX are similar; however, in the presence of activated factor VIIIa (intrinsic tenase complex), the normal augmentation of the cleavage of the specific substrate of factor IX, factor X, is not observed. The determination of the association constants for normal and variant factor IXa with factor VIIIa shows that the affinity of the activated variant factor IX for the cofactor factor VIIIa is 172-fold lower than normal. Competition studies using active site-inactivated factor IXas in the intrinsic tenase complex confirm that the defect in the variant protein is in its binding to factor VIIIa. We conclude that the structural integrity of the Gla domain of human factor IX is critical for the normal binding of factor IXa to factor VIIIa in the intrinsic tenase complex. In addition, a glycine at amino acid 12 is necessary for normal activation of factor IX by the factor VIIa-tissue factor complex