296 research outputs found
Photoemission spectra of LaMnO3 controlled by orbital excitations
We investigate the spectral function of a hole moving in the orbital-ordered
ferromagnetic planes of LaMnO, and show that it depends critically on the
type of orbital ordering. While the hole does not couple to the spin
excitations, it interacts strongly with the excitations of orbitals
(orbitons), leading to new type of quasiparticles with a dispersion on the
orbiton energy scale and with strongly enhanced mass and reduced weight.
Therefore we predict a large redistribution of spectral weight with respect to
the bands found in local density approximation (LDA) or in LDA+U.Comment: 4 pages, 4 figures, 3 figures embedded, figure 3 correcte
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Constraint-induced Aphasia Therapy versus Intensive Semantic Treatment in Fluent Aphasia
Objective: To compare the effectiveness of two intensive therapy methods: Constraint- 4 Induced Aphasia Therapy (CIAT) and semantic therapy (BOX).
Method: Nine patients with chronic fluent aphasia participated in a therapy programme 6 to establish behavioral treatment outcomes. Participants were randomly assigned to one of two groups (CIAT or BOX).
Results: Intensive therapy significantly improved verbal communication. However, BOX 9 treatment showed a more pronounced improvement on two communication measures, namely on a standardized assessment for verbal communication, the Amsterdam Nijmegen Everyday Language Test (Blomert, Koster, & Kean, 1995) and on a subjective rating scale, the Communicative Effectiveness Index (Lomas et al., 1989). All 13 participants significantly improved on one (or more) subtests of the Aachen Aphasia Test (Graetz et al., 1992), an impairment-focused assessment. There was a treatment-specific effect. Therapy with BOX had a significant effect on language comprehension and on semantics, while of CIAT affected language production and phonology.
Conclusion: The findings indicate that in patients with fluent aphasia (1) intensive treatment has a significant effect on language and verbal communication, (2) intensive therapy results in selective treatment effects and (3) an intensive semantic treatment shows a more striking mean improvement on verbal communication in comparison to communication-based CIAT-treatment
3D dSTORM imaging reveals novel detail of ryanodine receptor localization in rat cardiac myocytes
Cardiomyocyte contraction is dependent on Ca2+ release from ryanodine receptors (RyRs). However, the precise localization of RyRs remains unknown, due to shortcomings of imaging techniques which are diffraction limited or restricted to 2D. We aimed to determine the 3D nanoscale organization of RyRs in rat cardiomyocytes by employing direct stochastic optical reconstruction microscopy (dSTORM) with phase ramp technology. Initial observations at the cell surface showed an undulating organization of RyR clusters, resulting in their frequent overlap in the z‐axis and obscured detection by 2D techniques. Non‐overlapping clusters were imaged to create a calibration curve for estimating RyR number based on recorded fluorescence blinks. Employing this method at the cell surface and interior revealed smaller RyR clusters than 2D estimates, as erroneous merging of axially aligned RyRs was circumvented. Functional groupings of RyR clusters (Ca2+ release units, CRUs), contained an average of 18 and 23 RyRs at the surface and interior, respectively, although half of all CRUs contained only a single ‘rogue’ RyR. Internal CRUs were more tightly packed along z‐lines than surface CRUs, contained larger and more numerous RyR clusters, and constituted ∼75% of the roughly 1 million RyRs present in an average cardiomyocyte. This complex internal 3D geometry was underscored by correlative imaging of RyRs and t‐tubules, which enabled quantification of dyadic and non‐dyadic RyR populations. Mirroring differences in CRU size and complexity, Ca2+ sparks originating from internal CRUs were of longer duration than those at the surface. These data provide novel, nanoscale insight into RyR organization and function across cardiomyocytes
Orbital dynamics in ferromagnetic transition metal oxides
We consider a model of strongly correlated electrons interacting by
superexchange orbital interactions in the ferromagnetic phase of LaMnO. It
is found that the classical orbital order with alternating occupied
orbitals has a full rotational symmetry at orbital degeneracy, and the
excitation spectrum derived using the linear spin-wave theory is gapless. The
quantum (fluctuation) corrections to the order parameter and to the ground
state energy restore the cubic symmetry of the model. By applying a uniaxial
pressure orbital degeneracy is lifted in a tetragonal field and one finds an
orbital-flop phase with a gap in the excitation spectrum. In two dimensions the
classical order is more robust near the orbital degeneracy point and quantum
effects are suppressed. The orbital excitation spectra obtained using finite
temperature diagonalization of two-dimensional clusters consist of a
quasiparticle accompanied by satellite structures. The orbital waves found
within the linear spin-wave theory provide an excellent description of the
dominant pole of these spectra.Comment: 13 pages, 12 figures, to appear in Phys. Rev.
Manganites at Quarter Filling: Role of Jahn-Teller Interactions
We have analyzed different correlation functions in a realistic spin-orbital
model for half-doped manganites. Using a finite-temperature diagonalization
technique the CE phase was found in the charge-ordered phase in the case of
small antiferromagnetic interactions between electrons. It is shown
that a key ingredient responsible for stabilization of the CE-type spin and
orbital-ordered state is the cooperative Jahn-Teller (JT) interaction between
next-nearest Mn neighbors mediated by the breathing mode distortion of
Mn octahedra and displacements of Mn ions. The topological phase
factor in the Mn-Mn hopping leading to gap formation in one-dimensional models
for the CE phase as well as the nearest neighbor JT coupling are not able to
produce the zigzag chains typical for the CE phase in our model.Comment: 16 pages with 16 figures, contains a more detailed parameter estimate
based on the structural data by Radaelli et al. (accepted for publication in
Phys. Rev. B
Effects of the fungicide metiram in outdoor freshwater microcosms: responses of invertebrates, primary producers and microbes
The ecological impact of the dithiocarbamate fungicide metiram was studied in outdoor freshwater microcosms, consisting of 14 enclosures placed in an experimental ditch. The microcosms were treated three times (interval 7 days) with the formulated product BAS 222 28F (Polyram®). Intended metiram concentrations in the overlying water were 0, 4, 12, 36, 108 and 324 μg a.i./L. Responses of zooplankton, macroinvertebrates, phytoplankton, macrophytes, microbes and community metabolism endpoints were investigated. Dissipation half-life (DT50) of metiram was approximately 1–6 h in the water column of the microcosm test system and the metabolites formed were not persistent. Multivariate analysis indicated treatment-related effects on the zooplankton (NOECcommunity = 36 μg a.i./L). Consistent treatment-related effects on the phytoplankton and macroinvertebrate communities and on the sediment microbial community could not be demonstrated or were minor. There was no evidence that metiram affected the biomass, abundance or functioning of aquatic hyphomycetes on decomposing alder leaves. The most sensitive populations in the microcosms comprised representatives of Rotifera with a NOEC of 12 μg a.i./L on isolated sampling days and a NOEC of 36 μg a.i./L on consecutive samplings. At the highest treatment-level populations of Copepoda (zooplankton) and the blue-green alga Anabaena (phytoplankton) also showed a short-term decline on consecutive sampling days (NOEC = 108 μg a.i./L). Indirect effects in the form of short-term increases in the abundance of a few macroinvertebrate and several phytoplankton taxa were also observed. The overall community and population level no-observed-effect concentration (NOECmicrocosm) was 12–36 μg a.i./L. At higher treatment levels, including the test systems that received the highest dose, ecological recovery of affected measurement endpoints was fast (effect period < 8 weeks)
SN 2020jgb: A Peculiar Type Ia Supernova Triggered by a Massive Helium-Shell Detonation in a Star-Forming Galaxy
The detonation of a thin () helium shell
(He-shell) atop a white dwarf (WD) is a promising
mechanism to explain normal Type Ia supernovae (SNe Ia), while thicker
He-shells and less massive WDs may explain some recently observed peculiar SNe
Ia. We present observations of SN 2020jgb, a peculiar SN Ia discovered by the
Zwicky Transient Facility (ZTF). Near maximum light, SN 2020jgb is slightly
subluminous (ZTF -band absolute magnitude between and
mag depending on the amount of host galaxy extinction) and shows an unusually
red color ( between 0.4 and 0.2 mag) due to
strong line-blanketing blueward of 5000 . These properties
resemble those of SN 2018byg, a peculiar SN Ia consistent with a thick He-shell
double detonation (DDet) SN. Using detailed radiative transfer models, we show
that the optical spectroscopic and photometric evolution of SN 2020jgb are
broadly consistent with a (C/O core + He-shell;
up to depending on the total host extinction)
progenitor ignited by a thick () He-shell. We
detect a prominent absorption feature at 1 in the
near-infrared (NIR) spectrum of SN 2020jgb, which could originate from unburnt
helium in the outermost ejecta. While the sample size is limited, similar 1
features have been detected in all the thick He-shell DDet
candidates with NIR spectra obtained to date. SN 2020jgb is also the first
subluminous, thick He-shell DDet SN discovered in a star-forming galaxy,
indisputably showing that He-shell DDet objects occur in both star-forming and
passive galaxies, consistent with the normal SN Ia population.Comment: 23 pages, 10 figures. Updated to accepted version (ApJ
SN2017egm: A Helium-rich Superluminous Supernova with Multiple Bumps in the Light Curves
When discovered, SN~2017egm was the closest (redshift ) hydrogen-poor
superluminous supernova (SLSN-I) and a rare case that exploded in a massive and
metal-rich galaxy. Thus, it has since been extensively observed and studied. We
report spectroscopic data showing strong emission at around He~I
10,830 and four He~I absorption lines in the optical. Consequently, we
classify SN~2017egm as a member of an emerging population of helium-rich
SLSNe-I (i.e., SLSNe-Ib). We also present our late-time photometric
observations. By combining them with archival data, we analyze high-cadence
ultra-violet, optical, and near-infrared light curves spanning from early
pre-peak () to late phases (). We obtain its most
complete bolometric light curve, in which multiple bumps are identified. None
of the previously proposed models can satisfactorily explain all main
light-curve features, while multiple interactions between the ejecta and
circumstellar material (CSM) may explain the undulating features. The prominent
infrared excess with a blackbody luminosity of -- detected
in SN~2017egm could originate from the emission of either an echo of a
pre-existing dust shell, or newly-formed dust, offering an additional piece of
evidence supporting the ejecta-CSM interaction model. Moreover, our analysis of
deep observations yields the tightest-ever constraint on the X-ray
emission of an SLSN-I, amounting to an X-ray-to-optical luminosity ratio
at late phases (), which could help explore
its close environment and central engine.Comment: 25 pages, 14 Figures, 4 Tables; accepted for publication in ApJ (Mar.
2023
Depletion of B2 but Not B1a B Cells in BAFF Receptor-Deficient ApoE−/− Mice Attenuates Atherosclerosis by Potently Ameliorating Arterial Inflammation
We have recently identified conventional B2 cells as atherogenic and B1a cells as atheroprotective in hypercholesterolemic ApoE−/− mice. Here, we examined the development of atherosclerosis in BAFF-R deficient ApoE−/− mice because B2 cells but not B1a cells are selectively depleted in BAFF-R deficient mice. We fed BAFF-R−/− ApoE−/− (BaffR.ApoE DKO) and BAFF-R+/+ApoE−/− (ApoE KO) mice a high fat diet (HFD) for 8-weeks. B2 cells were significantly reduced by 82%, 81%, 94%, 72% in blood, peritoneal fluid, spleen and peripheral lymph nodes respectively; while B1a cells and non-B lymphocytes were unaffected. Aortic atherosclerotic lesions assessed by oil red-O stained-lipid accumulation and CD68+ macrophage accumulation were decreased by 44% and 50% respectively. B cells were absent in atherosclerotic lesions of BaffR.ApoE DKO mice as were IgG1 and IgG2a immunoglobulins produced by B2 cells, despite low but measurable numbers of B2 cells and IgG1 and IgG2a immunoglobulin concentrations in plasma. Plasma IgM and IgM deposits in atherosclerotic lesions were also reduced. BAFF-R deficiency in ApoE−/− mice was also associated with a reduced expression of VCAM-1 and fewer macrophages, dendritic cells, CD4+ and CD8+ T cell infiltrates and PCNA+ cells in lesions. The expression of proinflammatory cytokines, TNF-α, IL1-β and proinflammatory chemokine MCP-1 was also reduced. Body weight and plasma cholesterols were unaffected in BaffR.ApoE DKO mice. Our data indicate that B2 cells are important contributors to the development of atherosclerosis and that targeting the BAFF-R to specifically reduce atherogenic B2 cell numbers while preserving atheroprotective B1a cell numbers may be a potential therapeutic strategy to reduce atherosclerosis by potently reducing arterial inflammation
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