El papel de la tutoría en la formación integral del universitario

Las instituciones de educación requieren poner en marcha programas de tutoría para que los alumnos logren una formación integral, sin embargo, el reto al que se enfrentan es cómo llevarlos a cabo. El objetivo de este estudio consiste en presentar una propuesta para la instrumentación del Programa de Tutoría en las Instituciones de Educación Superior (IES). La metodología consiste en realizar un diagnóstico y análisis de los problemas presentados por la comunidad estudiantil, con el fin de planear las actividades y atender las necesidades académicas. Como resultado, se obtiene el programa de tutoría con las estrategias a seguir para atender las necesidades académicas detectadas, dar seguimiento y evaluar las acciones tutoriales.Las instituciones de educación requieren poner en marcha programas de tutoría para que los alumnos logren una formación integral, sin embargo, el reto al que se enfrentan es cómo llevarlos a cabo. El objetivo de este estudio consiste en presentar una propuesta para la instrumentación del Programa de Tutoría en las Instituciones de Educación Superior (IES). La metodología consiste en realizar un diagnóstico y análisis de los problemas presentados por la comunidad estudiantil, con el fin de planear las actividades y atender las necesidades académicas. Como resultado, se obtiene el programa de tutoría con las estrategias a seguir para atender las necesidades académicas detectadas, dar seguimiento y evaluar las acciones tutoriales

Una mariposa diferente. Cuidados al niño con epidermólisis bullosa

Trabajo fin de grado en EnfermeríaIntroducción La Epidermólisis Bullosa, comúnmente conocida como la "enfermedad de la piel de mariposa", es una de las miles de enfermedades raras. De origen genético, su patogenia subyace en una alteración de las proteínas de la unión dermo-epidérmica y se caracteriza por una gran fragilidad de la piel y de las mucosas desde el inicio de la vida, ocasionando numerosas lesiones ampollosas que condicionan la calidad de vida de los niños afectados. El objetivo de este trabajo es recoger la mejor y más actualizada información sobre los cuidados específicos que requieren los niños en esta situación de salud. Metodología Revisión narrativa a través de la búsqueda bibliográfica en las bases de datos de ciencias de la salud: PubMed, SciELO, Cochrane, Dialnet, Cuiden y CINAHL, además de en libros de texto, guías de práctica clínica y la consulta a profesionales y a familiares de pacientes. Resultados Se obtuvieron un total de 103 artículos que cumplían los criterios de inclusión, de los cuales tras su lectura se seleccionaron 37 debido a su relevancia para este trabajo. La revisión documental generó tres categorías de análisis: cuidados de la piel, recomendaciones nutricionales y manejo del dolor. Conclusiones Debido a que esta enfermedad en la actualidad carece de cura la labor de enfermería resulta esencial, tanto en relación a los cuidados como en la educación a las familias. Mantener la piel en las condiciones más óptimas posibles es fundamental para evitar el gran número de complicaciones que sufren estos niños.Introduction Epidermolysis bullosa (EB), often called “Butterfly Disease”, is one of thousands of rare diseases. With a genetic origin, the underlying pathogenesis is an alteration of dermo-epidermal junction proteins, and it is characterized by extremely fragile skin from the beginning of life, resulting in a large number of bullous lesions in both skin and mucous membranes, which affect the quality of life of affected children. The aim of this review is to collect the best and latest information on specific care required by children in this health situation. Methodology Narrative review from bibliographical research on databases of health sciences: PubMed, SciELO, Cochrane, Dialnet, Cuiden and CINAHL, in addition to textbooks, clinical practice guidelines and consultation to professionals and family patients Results They were obtained 103 papers that met the inclusion criteria, of which 37 were selected because of their relevance to this work. The document review generated three categories of analysis: skin care, nutritional recommendations and pain management. Conclusions Because it is a disease that currently has no cure, nursing work is especially essential, both in relation to the patient's care and education to families, to carry out this task at home. Keeping the skin under the most optimal conditions is essential to prevent many complications suffered by these children

Little lambs, linnets and babes in the snow: messages of kindness and caution in Christina Rossetti\u27s _Sing-Song_ and _Speaking Likenesses_

In this study of Christina Rossetti\u27s two books for children, Sing-Song: A Nursery Rhyme Book (1872) and Speaking Likenesses (1875), I use a feminist theoretical lens to examine the implicit directions given to young girls about how to be an appropriate girl, woman, mother, and citizen of the British Empire in the 19th century. In many ways, the poems and stories in these two books contain a subtle set of rules regarding behavior for the implied audience, which is largely middle-class, white, and Christian. These works for children written by Christina Rossetti reflect an interesting middle place between a feminist viewpoint and an insistence on abiding by a patriarchal set of rules. She seems to find a place that is neither adversarial to the existing patriarchal structures nor entirely satisfied by living within it. Both books celebrate the safety and love found in the mother-child relationship and expand that to portray the extended community of female care-givers, sisters, aunts, grandmothers, as nearly utopian. Sing-Song and Speaking Likenesses contain pieces which portray a respite from the temptations and dangers of the larger world in the female sphere of the nursery. Of particular interest in these two texts is the inclusion of a cautionary note on the fallen woman and the dangers of sensuality and promiscuity

Characterization of promoter regions of parotid gland genes.

BACKGROUND: Salivary secretion aids in digestion, host defense, and lubrication. Parotid salivary gland defects from Sjogren’s Syndrome affect more than one million Americans and cause dry mouth leading to oral disease. The Amylase 1 gene and the PSP gene are markers of parotid gland differentiation and indicate normal parotid gland function. Transcriptional activators of genes involved in parotid differentiation have not been characterized. HYPOTHESIS: Characterizing transcriptional activating sites in gene promoter regions will confirm upstream activating factors in bioinformatic network pathways. METHODS: Two promoter regions of mouse amylase 1 were identified using the ECR Browser, PCR amplified and ligated into a pGL4.10 luciferase vector. Transcriptional repressor binding sites were identified and removed from the 1 kbp region, followed by PCR amplification to produce fragments that were ligated into the minimal promoter pGL4.23 luciferase vector. These promoter clones were then transfected into three cell lines and tested for promoter activity. Bioinformatic analysis of microarray data determined correlations between increased transcription factor expression and markers of parotid differentiation. A hypothetical transcription factor network was created. Two interactions from the network predicted to activate the NUPR1 gene were Cited2/p300 and IRF2/PCAF. Mist1 was suggested to activate the PSP gene based on the hypothetical network. The promoter regions of NUPR1 and PSP were transfected into a parotid acinar cell line, and promoter activity was determined using dual luciferase assays with an internal Renilla control. RESULTS: The four amylase promoter clones, R1, R2-R1, 900bp, and 700bp were repressed as compared to a promoterless negative control, pGL4.10. The NUPR1 promoter was not activated by the co-transfected combination of Cited2/p300 or IRF2/PCAF. The PSP promoter alone was not activated by Mist1 transcription factor. However, PSP was activated when Mist1 was co-transfected with Tcf3 transcription factor and when intron regions containing E-box binding sites were added to the PSP promoter clone. CONCLUSION: Amylase 1 was not activated in the regions tested; therefore the active regions of the amylase 1 gene must be outside the 3 kbp region tested. NUPR1 is not activated by the predicted interactions of Cited2/p300 or IRF2/PCAF, so the results do not support the hypothetical transcription factor network. The PSP proximal promoter is not activated by Mist1, but a PSP promoter + intron construct is activated when the transcription factor Tcf3 + Mist1 are co-transfected

How We Were Not Sparrows

How We Were Not Sparrows is collection of numbered pieces that create lyrics essays on topics related to girlhood, womanhood and the expectations heaped upon the idea of both. My goal was to create a collection of pieces which when placed against or toward one another make something larger and also create surprising connections. I like to think about the finished work like an Advent calendar with miniature boxes that open to reveal a tiny picture of a mouse or a chocolate, full of bits that keep unfolding to expose another layer. Each essay includes a variety of perspectives interspersed to add texture to what is largely a personal and at times confessional book. The voice of the world or authority is present to bring the reader out of the too-close world of the writer into a larger cultural space. The world has a lot to say about who and what and where girls can be, the spaces they can hope to fill. Including these epigraphs is an attempt to create the same kind of jumble of voices in which girlhood is navigated

From Tevatron's top and lepton-based asymmetries to the LHC

We define a lepton-based asymmetry in semi-leptonic ttbar production at the LHC. We show that the ratio of this lepton-based asymmetry and the ttbar charge asymmetry, measured as a function of the lepton transverse momentum or the ttbar invariant mass is a robust observable in the Standard Model. It is stable against higher order corrections and mis-modeling effects. We show that this ratio can also be a powerful discriminant among different new physics models and between them and the Standard Model. Finally, we show that a related ratio defined at the Tevatron is also robust as a function of the ttbar invariant mass.Comment: 20 page

A developmental model for the pathogenenesis of cardiac arterio-ventricular fistulae

Coronary Artery Fistulae (CAF) are congenital coronary artery (CA) anomalies consisting of an abnormal communication of a coronary artery with either a cardiac chamber or a large cardiac vessel. Although their incidence in the Western population is low, CAF can lead to complications such as myocardial hypertrophy, endocarditis, heart dilatation and cardiac failure. CAFs can appear as an isolated anomaly or linked to some other forms of congenital heart disease like Left Ventricular Non-Compaction (LVNC) and intrinsic CA anatomy anomalies, but their etiology remains unknown. In this work we have used two different experimental models (transgenic mice and avian embryos) to investigate on the developmental mechanics of CAF formation. In order to tackle this goal, we have manipulated epicardial development and ventricular wall compaction, two inextricably related developmental events during coronary embryogenesis. Conditional integrin α4 gene deletion in the septum transversum/proepicardial (ST/PE) region (G2-Gata4+) disrupts early epicardium development and reduces cardiomyocyte proliferation, leading to the thinning of the ventricular compact myocardial layer. Reduction in compact myocardium thickness associates to the presence of multiple ventricular myocardial discontinuities and focal endocardial extrusion. This same phenotype can be experimentally reproduced in chick embryos using a cryocauterization method (Palmquist-Gomes et al., 2016). Our results suggest that the partial absence of epicardium in α4integrin;G2-Gata4Cre mouse embryos and the cryoinjury in avian embryos generate myocardial discontinuities in the embryonic ventricular wall, which promote endocardial extrusion towards the pericardial cavity and the early contact of the endocardium with coronary progenitors at the epicardial surface of the heart. In the case of avian embryos, this phenomenon leads to precocious smooth muscle differentiation from epicardial mesenchymal cells, and the formation of pouch-like structures that closely resemble CAF. We conclude that anomalous compact myocardial embryonic growth can originate CAF.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

A developmental model for the pathogenenesis of cardiac arterio-ventricular fistulae

Coronary Artery Fistulae (CAF) are congenital coronary artery (CA) anomalies consisting of an abnormal communication of a coronary artery with either a cardiac chamber or a large cardiac vessel. Although their incidence in the Western population is low, CAF can lead to complications such as myocardial hypertrophy, endocarditis, heart dilatation and cardiac failure. CAFs can appear as an isolated anomaly or linked to some other forms of congenital heart disease like Left Ventricular Non-Compaction (LVNC) and intrinsic CA anatomy anomalies, but their etiology remains unknown. In this work we have used two different experimental models (transgenic mice and avian embryos) to investigate on the developmental mechanics of CAF formation. In order to tackle this goal, we have manipulated epicardial development and ventricular wall compaction, two inextricably related developmental events during coronary embryogenesis. Conditional integrin α4 gene deletion in the septum transversum/proepicardial (ST/PE) region (G2-Gata4+) disrupts early epicardium development and reduces cardiomyocyte proliferation, leading to the thinning of the ventricular compact myocardial layer. Reduction in compact myocardium thickness associates to the presence of multiple ventricular myocardial discontinuities and focal endocardial extrusion. This same phenotype can be experimentally reproduced in chick embryos using a cryocauterization method (Palmquist-Gomes et al., 2016). Our results suggest that the partial absence of epicardium in α4integrin;G2-Gata4Cre mouse embryos and the cryoinjury in avian embryos generate myocardial discontinuities in the embryonic ventricular wall, which promote endocardial extrusion towards the pericardial cavity and the early contact of the endocardium with coronary progenitors at the epicardial surface of the heart. In the case of avian embryos, this phenomenon leads to precocious smooth muscle differentiation from epicardial mesenchymal cells, and the formation of pouch-like structures that closely resemble CAF. We conclude that anomalous compact myocardial embryonic growth can originate CAF.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech