619 research outputs found
Keck spectroscopy of the faint dwarf elliptical galaxy population in the Perseus Cluster core: mixed stellar populations and a flat luminosity function
We present the result of a photometric and Keck-LRIS spectroscopic study of
dwarf galaxies in the core of the Perseus Cluster, down to a magnitude of M_B =
-12.5. Spectra were obtained for twenty-three dwarf-galaxy candidates, from
which we measure radial velocities and stellar population characteristics from
absorption line indices. From radial velocities obtained using these spectra we
confirm twelve systems as cluster members, with the remaining eleven as
non-members. Using these newly confirmed cluster members, we are able to extend
the confirmed colour-magnitude relation for the Perseus Cluster down to M_B =
-12.5. We confirm an increase in the scatter about the colour magnitude
relationship below M_B = -15.5, but reject the hypothesis that very red dwarfs
are cluster members. We measure the faint-end slope of the luminosity function
between M_B = -18 and M_B = -12.5, finding alpha = -1.26 \pm 0.06, which is
similar to that of the field. This implies that an overabundance of dwarf
galaxies does not exist in the core of the Perseus Cluster. By comparing metal
and Balmer absorption line indices with alpha-enhanced single stellar
population models, we derive ages and metallicities for these newly confirmed
cluster members. We find two distinct dwarf elliptical populations: an old,
metal poor population with ages ~ 8 Gyr and metallicities [Fe/H] < -0.33, and a
young, metal rich population with ages
-0.33. Dwarf galaxies in the Perseus Cluster are therefore not a simple
homogeneous population, but rather exhibit a range in age and metallicity.Comment: 12 pages, 9 figures. Accepted for publication in MNRA
Influence of stream flow on epilithic diatom communities and its consequence for water quality monitoring
Epilithic diatom communities and relevant physico-chemical variables were studied between 3 May and 16 July 1993 in Harwood Beck, an oligotrophic stream in Upper Teesdale, and the River Browney, a lowland eutrophic river. The effect of stormflow on diatom-based water quality indices was assessed. In both rivers epilithic chlorophyll ḁ (µg cm(^-2)) was highly variable and very low after mid- June. In Harwood Beck there was a significant difference in epihthic chlorophyll a between cobbles and boulders, with the greatest difference after stormflow. Epilithic chlorophyll a in the River Browney was initially high, but declined markedly after stormflow. River Browney chlorophyll a was inversely correlated with current speed on cobbles and total inorganic nitrogen on cobbles and boulders. Uptake of inorganic nitrogen may be directly related to epilithic diatom biomass. A sharp rise in the percentage of Cocconeis placentula between mid-June and mid-July suggests that grazing may be an important factor limiting algal biomass. The possible roles of algal grazers, Cladophora glomerata and silicate concentration, in progressively limiting diatom biomass during the summer are discussed. Percentage composition changes of taxa after stormflow are generally related to taxa morphology and mode of adherance to the substrate. There were no significant differences in the percentages of the five most common taxa between cobbles and boulders. Percentage changes in taxa were not significantly correlated with nutrients, with the exception of Navicula gregaria and N. lanceolata (in the River Browney) which were inversely correlated with the concentration of total inorganic nitrogen. There appears to be a succession of dominant species, possibly related to the influence of flow and nutrient concentrations, which tended to increase during the study period. Diatom water quality indices remained relatively stable over the 10 week period. Effectively equal water quality classifications were derived from the Specific Pollution Index (SPI) and Generic Diatom Index (GDI). The zoning system proposed by Round (1993) may be broadly useful, but requires careful interpretation
Tidal interactions at the edge of the Local Group: New evidence for tidal features in the Antlia Dwarf Galaxy
Using deep B band imaging down to mu_{B} = 26 mag arcsec^{-2}, we present
evidence for tidal tails in the Antlia Dwarf galaxy, one of the most distant
members of the Local Group. This elongation is in the direction of Antlia's
nearest neighbor, the Magellanic-type NGC 3109. The tail is offset by less than
10 degrees from a vector linking the centers of the two galaxies, indicative of
interactions between the pair. Combined with the warped disc previously
identified in NGC 3109, Antlia and NGC 3109 must be at a small separation for
tidal features to be present in Antlia. We calculate that Antlia cannot be
completely disrupted by NGC 3109 in a single interaction unless its orbit
pericenter is less than 6 kpc, however multiple interactions could
significantly alter its morphology. Therefore despite being located right at
the edge of the Local Group, environmental effects are playing an important
role in Antlia's evolution.Comment: 8 pages, 4 figures, accepted for publication in ApJ
Molecular basis of interactions between CaMKII and α-actinin-2 that underlie dendritic spine enlargement
Ca2+/calmodulin-dependent protein kinase II (CaMKII) is essential for long-term potentiation (LTP) of excitatory synapses that is linked to learning and memory. In this study, we focused on understanding how interactions between CaMKIIα and the actin crosslinking protein α-actinin-2 underlie long-lasting changes in dendritic spine architecture. We found that association of the two proteins was unexpectedly elevated within two minutes of NMDA receptor stimulation that triggers structural LTP in primary hippocampal neurons. Furthermore, disruption of interactions between the two proteins prevented the accumulation of enlarged mushroom-type dendritic spines following NMDA receptor activation. α-actinin-2 binds to the regulatory segment of CaMKII. Calorimetry experiments, and a crystal structure of α-actinin-2 EF hands 3 and 4 in complex with the CaMKII regulatory segment, indicate that the regulatory segment of autoinhibited CaMKII is not fully accessible to α-actinin-2. Pull-down experiments show that occupation of the CaMKII substrate binding groove by GluN2B markedly increases α-actinin-2 access to the CaMKII regulatory segment. Furthermore, in situ labelling experiments are consistent with the notion that recruitment of CaMKII to NMDA receptors contributes to elevated interactions between the kinase and α-actinin-2 during structural LTP. Overall, our study provides new mechanistic insight into the molecular basis of structural LTP and reveals an added layer of sophistication to the function of CaMKII
Annual Survey of Virginia Law: Environmental Law
Recent developments in environmental law in Virginia continue to reflect several trends. These trends may be grouped into six general categories: (1) the growing tension between federal environmental mandates and their practical implementation through delegated state programs; (2) the continuing debate over the exact definition of interstate commerce and the scope of state authority to regulate in the gray area; (3) the impending deregulation of the electrical energy market; (4) the promotion of sustainable development; (5) the developing schism between state and local land use control; and (6) the evolving nature of administrative law in the environmental context. The following survey discusses changes to the body of environmental law affecting Virginians during 2000-2001 in the context of each of these trends
Isolated pores dissected from human two-pore channel 2 are functional.
Multi-domain voltage-gated ion channels appear to have evolved through sequential rounds of intragenic duplication from a primordial one-domain precursor. Whereas modularity within one-domain symmetrical channels is established, little is known about the roles of individual regions within more complex asymmetrical channels where the domains have undergone substantial divergence. Here we isolated and characterised both of the divergent pore regions from human TPC2, a two-domain channel that holds a key intermediate position in the evolution of voltage-gated ion channels. In HeLa cells, each pore localised to the ER and caused Ca2+ depletion, whereas an ER-targeted pore mutated at a residue that inactivates full-length TPC2 did not. Additionally, one of the pores expressed at high levels in E. coli. When purified, it formed a stable, folded tetramer. Liposomes reconstituted with the pore supported Ca2+ and Na+ uptake that was inhibited by known blockers of full-length channels. Computational modelling of the pore corroborated cationic permeability and drug interaction. Therefore, despite divergence, both pores are constitutively active in the absence of their partners and retain several properties of the wild-type pore. Such symmetrical 'pore-only' proteins derived from divergent channel domains may therefore provide tractable tools for probing the functional architecture of complex ion channels.This work was supported by BBSRC studentship BB/J014567 (CJP) and BBSRC grants BB/L006790 (BAW), BB/J019135 (BAW), BB/N01524X (SP) and BB/K000942 (SP). TR was supported by Royal Society grants RG69132 and RG65196. The SRCD studies were enabled by beamtime grants from the Soleil Synchrotron, France (to BAW)
Ultracompact dwarfs in the Perseus Cluster:UCD formation via tidal stripping
We present the results of a Keck/DEIMOS survey of Ultra Compact Dwarfs (UCDs)
in the Perseus Cluster core. We confirm cluster membership for 14 UCDs, with
radial velocities ~5300 km s. Two of these confirmed Perseus UCDs have
extremely blue colours ( mag), reside in star forming filaments
surrounding NGC 1275, and have likely formed as massive star clusters in the
last ~100 Myr. We also measure a central velocity dispersion of a third, UCD13
( km s), the most extended UCD in our sample. We
determine it to have radius pc, a dynamical mass of ( M, and a metallicity [Z/H] dex. UCD13 and the cluster's central galaxy, NGC 1275,
have a projected separation of 30 kpc and a radial velocity difference of ~20
km s. Based on its size, red colour, internal velocity dispersion,
dynamical mass, metallicity and proximity to NGC 1275, we argue that UCD13 is
likely the remnant nucleus of a tidally stripped dE, with this progenitor dE
having mag and mass M.Comment: 9 pages, 5 figures, accepted for publication in MNRA
Black hole scaling relations of active and quiescent galaxies: Addressing selection effects and constraining virial factors
Local samples of quiescent galaxies with dynamically measured black hole
masses (Mbh) may suffer from an angular resolution-related selection effect,
which could bias the observed scaling relations between Mbh and host galaxy
properties away from the intrinsic relations. In particular, previous work has
shown that the observed Mbh-Mstar (stellar mass) relation is more strongly
biased than the Mbh-sigma (velocity dispersion) relation. Local samples of
active galactic nuclei (AGN) do not suffer from this selection effect, as in
these samples Mbh is estimated from megamasers and/or reverberation
mapping-based techniques. With the exception of megamasers, Mbh-estimates in
these AGN samples are proportional to a virial coefficient fvir. Direct
modelling of the broad line region suggests that fvir~3.5. However, this
results in a Mbh-Mstar relation for AGN which lies below and is steeper than
the one observed for quiescent black hole samples. A similar though milder
trend is seen for the Mbh-sigma relation. Matching the high-mass end of the
Mbh-Mstar and Mbh-sigma relations observed in quiescent samples requires
fvir~15 and fvir~7, respectively. On the other hand, fvir~3.5 yields Mbh-sigma
and Mbh-Mstar relations for AGN which are remarkably consistent with the
expected `intrinsic' correlations for quiescent samples (i.e., once account has
been made of the angular resolution-related selection effect), providing
additional evidence that the sample of local quiescent black holes is biased.
We also show that, as is the case for quiescent black holes, the Mbh-Mstar
scaling relation of AGN is driven by velocity dispersion, thus providing
additional key constraints to black hole-galaxy co-evolution models.Comment: 15 pages, 5 Figures. MNRAS, accepte
High resolution HPLC-MS confirms overestimation of urea in soil by the diacetyl monoxime (DAM) colorimetric method
Hubble Space Telescope survey of the Perseus Cluster -IV: Compact stellar systems in the Perseus Cluster core and Ultra Compact Dwarf formation in star forming filaments
We present the results of the first search for Ultra Compact Dwarfs (UCDs) in
the Perseus Cluster core, including the region of the cluster around the
unusual Brightest Cluster Galaxy (BCG) NGC 1275. Utilising Hubble Space
Telescope Advanced Camera for Surveys imaging, we identify a sample of 84 UCD
candidates with half-light radii 10 pc < r_e < 57 pc out to a distance of 250
kpc from the cluster centre, covering a total survey area of ~70 armin^2. All
UCDs in Perseus lie in the same size-luminosity locus seen for confirmed UCDs
in other regions of the local Universe. The majority of UCDs are brighter than
M_R = -10.5, and lie on an extrapolation of the red sequence followed by the
Perseus Cluster dwarf elliptical population to fainter magnitudes. However,
three UCD candidates in the vicinity of NGC 1275 are very blue, with colours
(B-R)_0 < 0.6 implying a cessation of star formation within the past 100 Myr.
Furthermore, large blue star clusters embedded in the star forming filaments
are highly indicative that both proto-globular clusters (GCs) and proto-UCDs
are actively forming at the present day in Perseus. We therefore suggest star
forming filaments as a formation site for some UCDs, with searches necessary in
other low redshift analogues of NGC 1275 necessary to test this hypothesis. We
also suggest that tidal disruption of dwarf galaxies is another formation
channel for UCD formation in the core of Perseus as tidal disruption is ongoing
in this region as evidenced by shells around NGC 1275. Finally, UCDs may simply
be massive GCs based on strong similarities in the colour trends of the two
populations.Comment: 18 pages, 20 figures, 3 tables. Accepted for publication in MNRA
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