7,859 research outputs found
Process design for the manufacturing of soft X-ray gratings in single-crystal diamond by high-energy heavy-ion irradiation
This paper describes in detail a novel manufacturing process for optical gratings suitable for use in the UV and soft X-ray regimes in a single-crystal diamond substrate based on highly focused swift heavy-ion irradiation. This type of grating is extensively used in light source facilities such as synchrotrons or free electron lasers, with ever-increasing demands in terms of thermal loads, depending on beamline operational parameters and architecture. The process proposed in this paper may be a future alternative to current manufacturing techniques, providing the advantage of being applicable to single-crystal diamond substrates, with their unique properties in terms of heat conductivity and radiation hardness. The paper summarizes the physical principle used for the grating patterns produced by swift heavy-ion irradiation and provides full details for the manufacturing process for a specific grating configuration, inspired in one of the beamlines at the ALBA synchrotron light source, while stressing the most challenging points for a potential implementation. Preliminary proof-of-concept experimental results are presented, showing the practical implementation of the methodology proposed herein
Metal nanoparticles-PDMS nanocomposites for tunable optical filters and sensors
The peculiar optical response of polydimethylsiloxane (PDMS) doped with metallic nanoparticles can be employed to develop optical sensing materials. These nanocomposites may work in an ample range of temperatures, showing good linearity and high sensitivity. Plasmon resonances of the metallic nanoparticles produce interesting effects on the optical response by affecting the effective refractive index of PDMS. The high resonant response leads to a number of different configurations of optical filters and phase devices whose resonant frequency depends on the chosen nanoparticle. Moreover, the wavelength can be tuned up by external manufacturing conditions such as nanoparticle size or fill factor, and by working parameters such as temperature. This work develops the theoretical background required for the design of these structures, and evaluates the adequate dimensional and doping ranges for device optimization.This work was supported by Spanish Government RETOS Program grant no. TEC2013-47342-C2-R and no. TEC2013-50138-EXP, the R&D Program SINFOTON S2013/MIT-2790 of the Comunidad de Madrid, and the European COST Action IC1208
Eastern Mediterranean water outflow during the Younger Dryas was twice that of the present day
Eastern Mediterranean deep-intermediate convection was highly sensitive to varying inputs
of fresh water fluxes associated with increased rainfall during the African Humid period (15-6
kyr Before Present). Here we investigate changes in the water-outflow from the Eastern
Mediterranean Sea since the last deglaciation using neodymium isotope ratios. Our results
indicate enhanced outflow during the Younger Dryas, two times higher than present-day
outflow and about three times higher than during the last Sapropel. We propose that the
increased outflow into the western Mediterranean over the Younger Dryas was the result of
the combined effect of 1) enhanced climate-driven convection in the Aegean Sea and 2)
reduced convection of western deep water during this period. Our results provide solid
evidence for an enhanced Younger Dryas westward flow of Eastern Mediterranean sourced
waters in consonance with an intensification of Mediterranean water-outflow during a
weakened state of the Atlantic circulatio
Long-term precipitation in Southwestern Europe reveals no clear trend attributable to anthropogenic forcing
We present a long-term assessment of precipitation trends in Southwestern Europe (1850-2018) using data from multiple sources, including observations, gridded datasets and global climate model experiments. Contrary to previous investigations based on shorter records, we demonstrate, using new long-term, quality controlled precipitation series, the lack of statistically significant long-term decreasing trends in precipitation for the region. Rather, significant trends were mostly found for shorter periods, highlighting the prevalence of interdecadal and interannual variability at these time-scales. Global climate model outputs from three CMIP experiments are evaluated for periods concurrent with observations. Both the CMIP3 and CMIP5 ensembles show precipitation decline, with only CMIP6 showing agreement with long term trends in observations. However, for both CMIP3 and CMIP5 large interannual and internal variability among ensemble members makes it difficult to identify a trend that is statistically different from observations. Across both observations and models, our results make it difficult to associate any declining trends in precipitation in Southwestern Europe to anthropogenic forcing at this stage
Acute febrile illness is associated with Rickettsia spp infection in dogs
BACKGROUND: Rickettsia conorii is transmitted by Rhipicephalus sanguineus ticks and causes Mediterranean Spotted Fever (MSF) in humans. Although dogs are considered the natural host of the vector, the clinical and epidemiological significance of R. conorii infection in dogs remains unclear. The aim of this prospective study was to investigate whether Rickettsia infection causes febrile illness in dogs living in areas endemic for human MSF. METHODS: Dogs from southern Italy with acute fever (n = 99) were compared with case–control dogs with normal body temperatures (n = 72). Serology and real-time PCR were performed for Rickettsia spp., Ehrlichia canis, Anaplasma phagocytophilum/A. platys and Leishmania infantum. Conventional PCR was performed for Babesia spp. and Hepatozoon spp. Acute and convalescent antibodies to R. conorii, E. canis and A. phagocytophilum were determined. RESULTS: The seroprevalence rates at first visit for R. conorii, E. canis, A. phagocytophilum and L. infantum were 44.8%, 48.5%, 37.8% and 17.6%, respectively. The seroconversion rates for R. conorii, E. canis and A. phagocytophilum were 20.7%, 14.3% and 8.8%, respectively. The molecular positive rates at first visit for Rickettsia spp., E. canis, A. phagocytophilum, A. platys, L. infantum, Babesia spp. and Hepatozoon spp. were 1.8%, 4.1%, 0%, 2.3%, 11.1%, 2.3% and 0.6%, respectively. Positive PCR for E. canis (7%), Rickettsia spp. (3%), Babesia spp. (4.0%) and Hepatozoon spp. (1.0%) were found only in febrile dogs. The DNA sequences obtained from Rickettsia and Babesia PCRs positive samples were 100% identical to the R. conorii and Babesia vogeli sequences in GenBank®, respectively. Febrile illness was statistically associated with acute and convalescent positive R. conorii antibodies, seroconversion to R. conorii, E. canis positive PCR, and positivity to any tick pathogen PCRs. Fourteen febrile dogs (31.8%) were diagnosed with Rickettsia spp. infection based on seroconversion and/or PCR while only six afebrile dogs (12.5%) seroconverted (P = 0.0248). The most common clinical findings of dogs with Rickettsia infection diagnosed by seroconversion and/or PCR were fever, myalgia, lameness, elevation of C-reactive protein, thrombocytopenia and hypoalbuminemia. CONCLUSIONS: This study demonstrates acute febrile illness associated with Rickettsia infection in dogs living in endemic areas of human MSF based on seroconversion alone or in combination with PCR
Status of global fits to neutrino oscillations
We review the present status of global analyses of neutrino oscillations,
taking into account the most recent neutrino data including the latest KamLAND
and K2K updates presented at Neutrino2004, as well as state-of-the-art solar
and atmospheric neutrino flux calculations. We give the two-neutrino solar +
KamLAND results, as well as two-neutrino atmospheric + K2K oscillation regions,
discussing in each case the robustness of the oscillation interpretation
against departures from the Standard Solar Model and the possible existence of
non-standard neutrino physics. Furthermore, we give the best fit values and
allowed ranges of the three-flavour oscillation parameters from the current
worlds' global neutrino data sample and discuss in detail the status of the
small parameters \alpha \equiv \Dms/\Dma as well as ,
which characterize the strength of CP violating effects in neutrino
oscillations. We also update the degree of rejection of four-neutrino
interpretations of the LSND anomaly in view of the most recent developments.Comment: v6: In the last Appendix we provide updated neutrino oscillation
results which take into account the relevant oscillation data released by the
MINOS and KamLAND collaboration
Models of Neutrino Masses and Mixings
We review theoretical ideas, problems and implications of neutrino masses and
mixing angles. We give a general discussion of schemes with three light
neutrinos. Several specific examples are analyzed in some detail, particularly
those that can be embedded into grand unified theories.Comment: 44 pages, 2 figures, version accepted for publication on the Focus
Issue on 'Neutrino Physics' edited by F.Halzen, M.Lindner and A. Suzuki, to
be published in New Journal of Physics
Damping of supernova neutrino transitions in stochastic shock-wave density profiles
Supernova neutrino flavor transitions during the shock wave propagation are
known to encode relevant information not only about the matter density profile
but also about unknown neutrino properties, such as the mass hierarchy (normal
or inverted) and the mixing angle theta_13. While previous studies have
focussed on "deterministic" density profiles, we investigate the effect of
possible stochastic matter density fluctuations in the wake of supernova shock
waves. In particular, we study the impact of small-scale fluctuations on the
electron (anti)neutrino survival probability, and on the observable spectra of
inverse-beta-decay events in future water-Cherenkov detectors. We find that
such fluctuations, even with relatively small amplitudes, can have significant
damping effects on the flavor transition pattern, and can partly erase the
shock-wave imprint on the observable time spectra, especially for
sin^2(theta_13) > O(10^-3).Comment: v2 (23 pages, including 6 eps figures). Typos removed, references
updated, matches the published versio
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