Nonlinear differential equations in wavelet bases

In this paper we discuss the problem of finding numerical solution of some nonlinear differential equations using wavelet bases. It is also given a short outline of the method in dealing with the nonlinear heat equation.У статті обговорюється проблема чисельного розв'язання деяких нелінійних диференційних рівнянь із використанням вейвлет-базисів. У ній також дано короткий опис методу розв'язання нелінійного рівняння теплопровідності.В статье обсуждается проблема численного решения некоторых нелинейных дифференциальных уравнений с использованием вейвлет-базисов. В ней также дано краткое описание метода решения нелинейного уравнения теплопроводности

Np95 Is Implicated in Pericentromeric Heterochromatin Replication and in Major Satellite Silencing

Heterochromatin plays an important role in transcriptional repression, for the correct segregation of chromosomes and in the maintenance of genome stability. Pericentric heterochromatin (PH) replication and formation have been proposed to occur in the pericentric heterochromatin duplication body (pHDB). A central question is how the underacetylated state of heterochromatic histone H4 tail is established and controlled, because it is a key event during PH replication and is essential to maintain the compacted and silenced state of these regions. Np95 is a cell cycle regulated and is a nuclear histone-binding protein that also recruits HDAC-1 to target promoters. It is essential for S phase and for embryonic formation and is implicated in chromosome stability. Here we show that Np95 is part of the pHDB, and its functional ablation causes a strong reduction in PH replication. Depletion of Np95 also causes a hyperacetylation of lysines 8, 12, and 16 of heterochromatin histone H4 and an increase of pericentromeric major satellite transcription, whose RNAs are key players for heterochromatin formation. We propose that Np95 is a new relevant protein involved in heterochromatin replication and formation

Blood cyanide determination in two cases of fatal imtoxication: comparison between headspace gas chromatography and a spectrophotometric method

Blood samples of two cases were analyzed preliminarily by a classical spectrophotometric method (VIS) and by an automated headspace gas chromatographic method with nitrogen-phosphorus detector (HS-GC \u2044 NPD). In the former, hydrogen cyanide (HCN) was quantitatively determined by measuring the absorbance of chromophores forming as a result of interaction with chloramine T. In the automated HS-GC \u2044NPD method, blood was placed in a headspace vial, internal standard (acetonitrile) and acetic acid were then added. This resulted in cyanide being liberated as HCN. The spectrophotometric (VIS) and HS-GC\u2044NPD methods were validated on postmortem blood samples fortified with potassium cyanide in the ranges 0.5\u201310 and 0.05\u20135 lg \u2044 mL, respectively. Detection limits were 0.2 lg \u2044mL for VIS and 0.05 lg \u2044mL for HS-GC\u2044NPD. This work shows that results obtained by means of the two procedures were insignificantly different and that they compared favorably. They are suitable for rapid diagnosis of cyanide in postmortem cases

Enhancing H2 production rate in PGM-free photoelectrochemical cells by glycerol photo-oxidation

The photo-oxidation of glycerol was carried out by using TiO2 NTs photoanodes and Ni foam as the cathode for the Hydrogen Evolution Reaction. The photoanodes were prepared by anodizing Ti foils and titanium felt and then annealed under air exposure. They were tested in acidic aqueous solution without and with the addition of glycerol. When glycerol was present, the hydrogen production rate increased and allowed the simultaneous production of high value added partial oxidation compounds, i.e. 1,3-dihydroxyacetone (DHA), and glyceraldehyde (GA). The highest H2 evolution and partial oxidation compounds production rates were obtained by using home prepared TiO2 nanotubes (TiO2 NTs) synthesized on Ti fiber felt as the photoanode with an irradiated area of 90 cm2. These photoanodes were found to be highly stable both from a mechanical and a chemical point of view, so they can be reused after a simple cleaning step

Akute Gefäßerkrankungen in der Gastroenterologie

Zusammenfassung: Vaskulär-gastroenterologische Notfälle zählen zu den häufigen Krankheitsbildern auf internistischen und chirurgischen Notfallstationen. Die klinischen Konsequenzen reichen von trivialen bis zu lebensbedrohlichen Situationen. Nur eine frühzeitige Erkennung der Symptomenkomplexe und die Anwendung der adäquaten diagnostischen Mittel führen zur korrekten Diagnosestellung mit nachfolgend - möglicherweise lebensrettender - Therapie. Um die hohen Mortalitätsraten der akuten Mesenterialischämien (50%), aortoenterischen Fisteln (30-40%), Aneurysmen viszeraler Arterien (10-100%) sowie des Budd-Chiari-Syndroms weiter senken zu können, gewinnen neue Strategien mit endovaskulärem Therapieansatz zunehmend an Bedeutung und ersetzen teilweise über viele Jahrzehnte etablierte Diagnose- und Therapiealgorithmen. Diese Übersichtsarbeit soll einen Überblick über aktuelle Diagnostik- und Therapiekonzepte häufiger vaskulär-gastroenterologischer Notfälle verschaffe

Photocatalytic and photoelectrocatalytic H2 evolution combined with valuable furfural production

In this work the photocatalytic (PC) and photoelectrocatalytic (PEC) reforming of furfuryl alcohol (FA) under environmental friendly conditions was investigated. Both H2 evolution and partial oxidation to furfuraldehyde were followed. For the first time TiO2 based photocatalysts were studied and the photocatalytic activity of home prepared photocatalysts was compared with that of commercial ones under both UVA and simulated solar irradiation. PEC tests were performed by using home prepared TiO2 nanotubes (TiO2 NTs) as photoanode and Pt free Ni foam as cathode to improve the Hydrogen Evolution Reaction (HER). Both the partial FA oxidation reaction rate and H2 evolution rate were normalized for the lamp specific power to account for the different photon flux and the rates were higher for PEC process. PEC is a promising strategy for the valorization of biomasses with simultaneous H2 production in spite of the cost of the bias

A Unique LnIII{[3.3.1]GaIII Metallacryptate} Series That Possesses Properties of Slow Magnetic Relaxation and Visible/Near‐Infrared Luminescence

A new family of [3.3.1] metallacryptates with the general composition [LnGa6(H2shi)(Hshi)(shi)7(C5H5N)] (Ln‐1; shi3−=salicylhydroximate; Ln = Pr, Nd, Sm–Yb) has been synthesized and characterized. Ln‐1 display both interesting magnetic and luminescent properties. Sm‐1 has sharp emission bands in the visible and the near‐infrared (NIR) regions with quantum yield values (QSmL) of 1.64(9) and 5.5(2).10−2 %, respectively. Tb‐1 exhibits a weak green emission (QTbL=1.89(3).10−1 %) while Pr‐1, Nd‐1, Ho‐1, Er‐1, and Yb‐1 possess emission bands in the NIR range with QPrL=3.7(2).10−3 %, QNdL=1.71(5).10−1 %, QHoL=1.1(2).10−3 %, QErL=7.1(2).10−3 % and QYbL=0.65(3) %. Nd‐1, Dy‐1, and Yb‐1 display slow magnetization relaxation in an applied field, where only Dy‐1 has been observed to follow an Orbach process (Ueff=12.7 K). The combination of NIR emission with magnetic properties makes Nd‐1 and Yb‐1 attractive candidates as smart materials addressable in two manners.A two‐for‐one scaffold: A new LnIII‐encapsulating metallamacrocyclic scaffold was synthesized and structurally determined to resemble cryptands. This metallacryptand can bind a wide variety of LnIII ions of different natures and demonstrates the ability to sensitize their characteristic emissions in the visible and/or near‐infrared. Slow magnetic relaxation was also observed for selected LnIII.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/145255/1/chem201801355.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/145255/2/chem201801355_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/145255/3/chem201801355-sup-0001-misc_information.pd

Evaluation of the SUNHEART Cardiology Outreach Programme

Introduction: The demand for advanced cardiac care and specialised interventions is on the increase and this results in bottlenecks and increased waiting times for patients who require advanced cardiac care. By decentralising cardiac care, and using a hub-and-spoke model, the SUNHEART Outreach Programme of cardiovascular care aims to improve access to advanced cardiac care in the Western Cape. Tygerberg Hospital is the central hub, with the fi rst spoke being Paarl Hospital. Objective: To determine the value of the SUNHEART Outreach Programme to the public health care system. Methods: An audit of patients accessing the OutreachProgramme was performed for the period May 2013 - May 2014 and consequently compared to a historical cohort of patients accessing the health care system during the preceding 6 months, from October 2012 -April 2013. Access to advanced cardiac care was measured in time to initial evaluation, time to defi nitive diagnosis or intervention and patient compliance with appointments. The value to the health care system was also assessed by performing a cost analysis of transport of patients and health care workers, as well as compliance with appointments. We documented the spectrum of disease requiring advanced cardiac care toguide future interventions. Results: Data of 185 patients were included in the audit. Sixty four patients were referred to tertiary care from October 2012 - April 2013 and 121 patients were referred to the outreach facility from May 2013 - May 2014. There was a signifi cant reduction in waiting times with the median days to appointment of the historical cohort being 85 days compared to 18 days in the Outreach Programme cohort (p<0.01). Patient compliance with appointments was signifi cantly superior in the Outreach Programme cohort (90% vs. 56%: p<0.01). Valvular (36.5%) and ischaemic heart disease (35.5%) were the major pathologies requiring access to cardiac care services. Transport costs per patient treated was signifi cantly reduced in the outreach programme cohort (R118,09 vs. R308,77). Conclusion: Decentralisation of services in the form of an Outreach Programme, with a central hub, improves access to advanced cardiac care by decreasing waiting time, improving compliance with appointments and decreasing travel costs