Parametric evaluation of impedance curve in radiofrequency ablation : a quantitative description of the asymmetry and dynamic variation of impedance in bovine ex vivo model

Radiofrequency ablation (RFA) is a treatment for liver tumors with advantages over the traditional treatment of surgical resection. This procedure has the shortest recovery time in early stage tumors. The objective of this study is to parameterize the impedance curve of the RFA procedure in an ex vivo model by defining seven parameters (t1/2, tminimum, tend, Zinitial, Z1/2, Zminimum and Zend). Based on these parameters, three performance indices are defined: one to identify the magnitude of impedance curve asymmetry (δ), one Drop ratio (DR) describing the percentage of impedance decrease until the minimum impedance point is reached, and Ascent Ratio (AR) describing the magnitude of increase in impedance from the minimum impedance point to its maximum point. Fifty ablations were performed in a bovine ex vivo model to measure and evaluate the proposed parameters and performance index. The results show that the groups had an average δ of 29.02%, DR of 22.41%, and AR of 545.33% for RFA without the use of saline or deionized solutions. The saline solution and deionized water-cooled groups indicated the correlation of performance indices δ, DR, and AR with the obtained final ablation volume. Therefore, by controlling these parameters and indices, lower recurrence is achieved

A política de habitação rural e o desenvolvimento da agricultura familiar.

Este artigo analisa a contribuição do Programa Nacional de Habitação Rural (PNHR) para o desenvolvimento de territórios predominantemente rurais. A partir do estudo de sua implementação na região Oeste Catarinense, ponder sobre os avanços e as restrições desta política social. Para as análises realizadas procedeu-se a uma revisão de literatura, à busca de documentação sobre a política e sua implementação na região estudada, bem como a entrevistas com lideranças e agricultores demandantes e beneficiados por uma casa nova ou reforma. Verificou-se que o PNHR cria uma oportunidade para as famílias rurais descapitalizadas construírem ou reformarem sua casa, apesar de ser ainda restrita a sua abrangência para o conjunto dessas famílias. A reformulação do programa, reduzindo exigências financeiras e para operação dos créditos, pode oportunizar que maior número de famílias dele se beneficie, com impacto social positivo no desenvolvimento regional

CONTROLE DE ORIENTAÇÃO E VELOCIDADE DE CADEIRA DE RODAS POR VISÃO COMPUTACIONAL

This work proposes a computer vision system for wheelchair control based on facial coordinates and head position estimation. This work comprises the design of a low-cost motorized wheelchair, which aims to promote independence and quality of life for people who have motor difficulties to manipulate a joystick. The tests performed on the built prototype resulted in an accuracy of 87.78%, an precision of 90.00% and a sensitivity of 87.70%. Tests performed in the motorized wheelchair resulted in an average accuracy of 94.69%, average precision of 91.04% and average sensitivity of 89.38%.Este trabalho propõe um sistema de visão computacional para controle de cadeira de rodas com base em coordenadas faciais e estimativa da posição da cabeça. Este trabalho compõe o projeto de uma cadeira de rodas motorizada de baixo custo, que tem como objetivo promover independência e qualidade de vida a pessoas que possuem dificuldades motoras para manipular um joystick. Os testes realizados no protótipo construído resultaram em uma acurácia de 87,78%, a precisão de 90,00% e uma sensibilidade de 87,70%. Os testes realizados na cadeira de rodas motorizada resultaram em uma acurácia média de 94,69%, precisão média de 91,04% e sensibilidade média de 89,38%

Painel: a dívida externa dos países em desenvolvimento e o caso brasileiro

A publicação deste painel foge à tradição editorial desta revista, mas a leitura da transcrição da fita gravado nos levou a esta decisão

Immunogenicity and Reactogenicity of 2009 Influenza A (H1N1) Inactivated Monovalent Non-Adjuvanted Vaccine in Elderly and Immunocompromised Patients

Background\ud \ud Immunosuppressed individuals present serious morbidity and mortality from influenza, therefore it is important to understand the safety and immunogenicity of influenza vaccination among them.\ud Methods\ud \ud This multicenter cohort study evaluated the immunogenicity and reactogenicity of an inactivated, monovalent, non-adjuvanted pandemic (H1N1) 2009 vaccine among the elderly, HIV-infected, rheumatoid arthritis (RA), cancer, kidney transplant, and juvenile idiopathic arthritis (JIA) patients. Participants were included during routine clinical visits, and vaccinated according to conventional influenza vaccination schedules. Antibody response was measured by the hemagglutination-inhibition assay, before and 21 days after vaccination.\ud Results\ud \ud 319 patients with cancer, 260 with RA, 256 HIV-infected, 149 elderly individuals, 85 kidney transplant recipients, and 83 with JIA were included.\ud \ud The proportions of seroprotection, seroconversion, and the geometric mean titer ratios postvaccination were, respectively: 37.6%, 31.8%, and 3.2 among kidney transplant recipients, 61.5%, 53.1%, and 7.5 among RA patients, 63.1%, 55.7%, and 5.7 among the elderly, 59.0%, 54.7%, and 5.9 among HIV-infected patients, 52.4%, 49.2%, and 5.3 among cancer patients, 85.5%, 78.3%, and 16.5 among JIA patients. The vaccine was well tolerated, with no reported severe adverse events.\ud Conclusions\ud \ud The vaccine was safe among all groups, with an acceptable immunogenicity among the elderly and JIA patients, however new vaccination strategies should be explored to improve the immune response of immunocompromised adult patients. (ClinicalTrials.gov, NCT01218685)Fundação Butantan funded the study, and employed several of the authors. The funder had a role in study design, data collection and analysis, decision to publish, or preparation of the manuscript