10 research outputs found
Angioedema hereditário : revisão, apresentação de uma famÃlia com 15 indivÃduos afetados e correlação com sistema HLA
Os autores apresentam sua experiência com o angioedema hereditário, descrevendo diversos casos no Rio Grande do Sul. As famÃlias acometidas foram investigadas com dosagem de C4, tipagem HLA, grupo sangüÃneo e R h. Concluiu-se que não existe relação entre o surgimento da doença e antÃgenos de histocompatibilidade, grupos sangüÃneos ABO e R h. A dosagem de C4 é importante na confirmação do diagnóstico clÃnico.The authors present their experience with Hereditary Angioedema describing many cases in one family from Rio Grande do Sul. The afflicted family was investigated by C4 measurements, HLA typing, as well as typing for blood groups and the Rh system. The conclusion was that there is no association between the appearance of the disease and histocompatibility antigens, blood groups ABO or Rh. The measurement of C4 is important in establishing the diagnosis of Hereditary Angioedema
SÃndrome pós-pericardiotomia : comportamento dos marcadores séricos de injúria tecidual e de resposta inflamatória
Community-acquired pneumonia by Legionella pneumophila serogroups 1–6 in Brazil
SummaryA prospective cohort study of adult patients hospitalized due to community-acquired pneumonia was carried out for 1 year in a Brazilian university general hospital to detect the incidence of community-acquired pneumonia by Legionella pneumophila serogroups 1–6. During a whole year, a total of 645 consecutive patients who were hospitalized due to a initial presumptive diagnosis of respiratory disease by ICD-10 (J00–J99), excluding upper respiratory diseases, were screened to detect the patients with community-acquired pneumonia. Fifty-nine consecutive patients hospitalized due to community-acquired pneumonia between July 19, 2000 and July 18, 2001, were included in the study. They had determinations of serum antibodies to L. pneumophila serogroups 1–6 by indirect immunofluorescence antibody test at the Infectious Diseases Laboratory of University of Louisville (KY, USA) and urinary antigen tests for L. pneumophila serogroup 1. Three patients had community-acquired pneumonia by L. pneumophila serogroups 1–6, two patients being diagnosed by seroconversion and positive urinary antigen tests; the other had negative serologies but strongly positive urinary antigen test. The incidence of community-acquired pneumonia by L. pneumophila serogroups 1–6 in our hospital was 5.1%
Receptores de membrana de linfocitos em pacientes com hanseniase
BV UNIFESP: Teses e dissertaçõe
Diagnóstico laboratorial da infecção pelo HIV utilizando diversidades de fluidos biológicos com proposta de estabelecimento de novos fluxogramas
Diagnóstico laboratorial da infecção pelo HIV utilizando diversidades de fluidos biológicos com proposta de estabelecimento de novos fluxogramas
Behavior of inflammatory markers of myocardial injury in cardiac surgery : laboratory correlation with the clinical picture of potpericardiotomy syndrome
Objective- To verify the association of serum markers of myocardial injury, such as troponin I, creatinine kinase, and creatinine kinase isoenzyme MB, and inflammatory markers, such as tumor necrosis factor alpha (TNF-alpha), C-reactive protein, and the erythrocyte sedimentation rate in the perioperative period of cardiac surgery, with the occurrence of possible postpericardiotomy syndrome. Methods- This was a cohort study with 96 patients undergoing cardiac surgery assessed at the following 4 different time periods: the day before surgery (D0); the 3rd postoperative day (D3); between the 7th and 10th postoperative days (D7-10); and the 30th postoperative day (D30). During each period, we evaluated demo- graphic variables (sex and age), surgical variables (type and duration , extracorporeal circulation), and serum dosages of the markers of myocardial injury and inflam- matory response. Results - Of all patients, 12 (12.5%) met the clinical criteria for a diagnosis of postpericardiotomy syndrome, and their mean age was 10.3 years lower than the age of the others (P=0.02). The results of the serum markers for tissue injury and inflammatory response were not signifi- cantly different between the 2 assessed groups. No signifi- cant difference existed regarding either surgery duration or extracorporeal circulation. Conclusio- The patients who met the clinical criteria for postpericardiotomy syndrome were significan- tly younger than the others were. Serum markers for tissue injury and inflammatory response were not different in the clinically affected group, and did not correlate with the different types and duration of surgery or with extracorpo- real circulation
Behavior of inflammatory markers of myocardial injury in cardiac surgery : laboratory correlation with the clinical picture of potpericardiotomy syndrome
Objective- To verify the association of serum markers of myocardial injury, such as troponin I, creatinine kinase, and creatinine kinase isoenzyme MB, and inflammatory markers, such as tumor necrosis factor alpha (TNF-alpha), C-reactive protein, and the erythrocyte sedimentation rate in the perioperative period of cardiac surgery, with the occurrence of possible postpericardiotomy syndrome. Methods- This was a cohort study with 96 patients undergoing cardiac surgery assessed at the following 4 different time periods: the day before surgery (D0); the 3rd postoperative day (D3); between the 7th and 10th postoperative days (D7-10); and the 30th postoperative day (D30). During each period, we evaluated demo- graphic variables (sex and age), surgical variables (type and duration , extracorporeal circulation), and serum dosages of the markers of myocardial injury and inflam- matory response. Results - Of all patients, 12 (12.5%) met the clinical criteria for a diagnosis of postpericardiotomy syndrome, and their mean age was 10.3 years lower than the age of the others (P=0.02). The results of the serum markers for tissue injury and inflammatory response were not signifi- cantly different between the 2 assessed groups. No signifi- cant difference existed regarding either surgery duration or extracorporeal circulation. Conclusio- The patients who met the clinical criteria for postpericardiotomy syndrome were significan- tly younger than the others were. Serum markers for tissue injury and inflammatory response were not different in the clinically affected group, and did not correlate with the different types and duration of surgery or with extracorpo- real circulation