20 research outputs found
Oficinas educativas y la sistematización de la asistencia de enfermería en salud mental
It presents the results of research on educational workshops focused on self-care, highlighting its applicability in the implementation of Nursing Care Systematization (NCS) in Mental Health. The workshops were based on the principles of Psychiatric Reform and were held as part of nursing care in a care service of children and adolescents Mental Health. The investigation was conducted by analyzing the workshop records held from April 2010 to November 2011. It was concluded that the workshops are a space for nursing interventions, health promotion, corrections of self-care deficit and psychosocial rehabilitation, and effectively contribute to the process of Systematization of Nursing Care in mental health.Apresentam-se, neste trabalho, os resultados da investigação sobre oficinas educativas direcionadas ao autocuidado, destacando-se a sua aplicabilidade na implementação da Sistematização da Assistência de Enfermagem em saúde mental. As oficinas fundamentaram-se nos princípios da Reforma Psiquiátrica e foram realizadas como parte da assistência de enfermagem em um serviço de atenção à saúde mental da criança e do adolescente. A investigação foi feita com base na análise dos registros das oficinas realizadas no período de abril de 2010 a novembro de 2011. Concluiu-se que as oficinas constituíram um espaço para intervenções de Enfermagem, promoção de saúde, correções do déficit de autocuidado e reabilitação psicossocial, além de contribuir, efetivamente, para o processo de Sistematização da Assistência de Enfermagem em saúde mental.Se presenta los resultados de la averiguación sobre oficinas educativas dirigidas al autocuidado, destacando su aplicabilidad en la implementación de la Sistematización de la Asistencia de Enfermería (SAE) en Salud Mental. Las oficinas se fundamentaron en los principios de la Reforma Psiquiátrica y fueron realizadas como parte de la asistencia de enfermería en un servicio de atención a la Salud Mental del niño y del adolescente. La averiguación fue hecha del análisis de los registros de las oficinas realizadas en el período de abril de 2010 a noviembre de 2011. Se concluyó que las oficinas constituyeron en un espacio para intervenciones de enfermería, promoción de salud, correcciones del déficit de autocuidado y rehabilitación psicosocial, además de aportar, efectivamente, para el proceso de Sistematización de la Asistencia de Enfermería en salud mental
Treinamento simulado para estudantes de medicina e médicos em manejo de via aérea em pacientes covid-19
ANÁLISE DO EQUILÍBRIO EM PACIENTES HEMIPARÉTICOS COM INTERVENÇÃO DA REABILITAÇÃO EQUESTRE
O objetivo desta pesquisa foi analisar através da Escala Funcional de Equilíbrio de Berg e SF- 36, a influência da reabilitação equestre no tratamento dos distúrbios do equilíbrio em pacientes hemiplégicos. Tratou-se de um relato de casos realizado no Centro de Reabilitação Equestre da UNOESTE, onde foram avaliados 3 indivíduos hemiplégicos com distúrbios de equilíbrio, antes e após 8 sessões de equoterapia, seguindo um mesmo protocolo de tratamento. Os resultados mostraram que houve uma melhora de 7,14% no indivíduo 1, representando 4 pontos do total da escala. O indivíduo 2 manteve-se dentro do nível de corte não podendo classificá-lo com déficit de equilíbrio significativo e o indivíduo 3 permaneceu abaixo do nível de corte como na avaliação inicial. A reabilitação equestre mostrou-se relevante no tratamento de distúrbios de equilíbrio em pacientes hemiplégicos
Inovações frente ao ensino tradicional : treinamento em acessos venosos centrais através de simulação
Questão agrária e políticas públicas em Minas Gerais : conflitos sociais e alternativas populares
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Leishmania amazonensis DNA in wild females ofLutzomyia cruzi (Diptera: Psychodidae) in the state of Mato Grosso do Sul, Brazil
Evaluation of a Propolis Water Extract Using a Reliable RP-HPLC Methodology and In Vitro and In Vivo Efficacy and Safety Characterisation
Since the beginning of propolis research, several groups have studied its antibacterial, antifungal, and antiviral properties. However, most of these studies have only employed propolis ethanolic extract (PEE) leading to little knowledge about the biological activities of propolis water extract (PWE). Based on this, in a previous study, we demonstrated the anti-inflammatory and immunomodulatory activities of PWE. In order to better understand the equilibrium between effectiveness and toxicity, which is essential for a new medicine, the characteristics of PWE were analyzed. We developed and validated an RP-HPLC method to chemically characterize PWE and PEE and evaluated the in vitro antioxidant/antimicrobial activity for both extracts and the safety of PWE via determining genotoxic potential using in vitro and in vivo mammalian micronucleus assays. We have concluded that the proposed analytical methodology was reliable, and both extracts showed similar chemical composition. The extracts presented antioxidant and antimicrobial effects, while PWE demonstrated higher antioxidant activity and more efficacious for the most of the microorganisms tested than PEE. Finally, PWE was shown to be safe using micronucleus assays
Prevention of Elevation in Plasma Triacylglycerol with High-Dose Bezafibrate Treatment Abolishes Insulin Resistance and Attenuates Glucose Intolerance Induced by Short-Term Treatment with Dexamethasone in Rats
Objective. Fibrates are used as lipid-lowering drugs and are well tolerated as cotreatments when glucose metabolism disturbances are also present. Synthetic glucocorticoids (GCs) are diabetogenic drugs that cause dyslipidemia, dysglycemia, glucose intolerance, and insulin resistance when in excess. Thus, we aimed to describe the potential of bezafibrate in preventing or attenuating the adverse effects of GCs on glucose and lipid homeostasis. Methods. Male Wistar rats were treated with high-dose bezafibrate (300 mg/kg, body mass (b.m.)) daily for 28 consecutive days. In the last five days, the rats were also treated with dexamethasone (1 mg/kg, b.m.). Results. Dexamethasone treatment reduced the body mass gain and food intake, and bezafibrate treatment exerted no impact on these parameters. GC treatment caused an augmentation in fasting and fed glycemia, plasma triacylglycerol and nonesterified fatty acids, and insulinemia, and bezafibrate treatment completely prevented the elevation in plasma triacylglycerol and attenuated all other parameters. Insulin resistance and glucose intolerance induced by GC treatment were abolished and attenuated, respectively, by bezafibrate treatment. Conclusion. High-dose bezafibrate treatment prevents the increase in plasma triacylglycerol and the development of insulin resistance and attenuates glucose intolerance in rats caused by GC treatment, indicating the involvement of dyslipidemia in the GC-induced insulin resistance
Melatonin Regulates the Daily Levels of Plasma Amino Acids, Acylcarnitines, Biogenic Amines, Sphingomyelins, and Hexoses in a Xenograft Model of Triple Negative Breast Cancer
Metabolic dysregulation as a reflection of specific metabolite production and its utilization is a common feature of many human neoplasms. Melatonin, an indoleamine that is highly available during darkness, has a variety of metabolic functions in solid tumors. Because plasma metabolites undergo circadian changes, we investigated the role of melatonin on the profile of amino acids (AAs), biogenic amines, carnitines, sphingolipids, and hexoses present in the plasma of mice bearing xenograft triple negative breast cancer (MDA-MB-231 cells) over 24 h. Plasma concentrations of nine AAs were reduced by melatonin, especially during the light phase, with a profile closer to that of non-breast cancer (BC) animals. With respect to acylcarnitine levels, melatonin reduced 12 out of 24 molecules in BC-bearing animals compared to their controls, especially at 06:00 h and 15:00 h. Importantly, melatonin reduced the concentrations of asymmetric dimethylarginine, carnosine, histamine, kynurenine, methionine sulfoxide, putrescine, spermidine, spermine, and symmetric dimethylarginine, which are associated with the BC metabolite sets. Melatonin also led to reduced levels of sphingomyelins and hexoses, which showed distinct daily variations over 24 h. These results highlight the role of melatonin in controlling the levels of plasma metabolites in human BC xenografts, which may impact cancer bioenergetics, in addition to emphasizing the need for a more accurate examination of its metabolomic changes at different time points