541 research outputs found
Output feedback control of flow separation over an aerofoil using plasma actuators
We address the problem of controlling the unsteady flow separation over an aerofoil, using plasma actuators. Despite the complexity of the dynamics of interest, we show how the problem of controlling flow separation can be formulated as a simple set-point tracking problem, so that a simple control strategy may be used. A robust output feedback control is designed, on the basis of a low-order, linear, dynamical model approximating the incompressible Navier-Stokes equations, obtained from the snapshots of 2D laminar finite element simulations at Re=1,000. Fast flow reattachment is achieved, along with both stabilisation and increase/reduction of the lift/drag, respectively. Accurate 2D finite element simulations of the full-order nonlinear equations illustrate the effectiveness of the proposed approach: good dynamic performances are obtained, as both the Reynolds number and the angle of attack are varied. The chosen output can be experimentally measured by appropriate sensors and, despite its simplicity, the proposed set-point tracking controller is sufficient to suppress the laminar separation bubble; moreover, its extension to 3D turbulent configurations is straightforward, thus illustrating the effectiveness of the designed control algorithm in more practical conditions, which are far from the design envelope
Collisional Excitation of CO by 2.3 eV H Atoms
Vibrational and rotational distributions of CO excited by collisions with 2.3 eV H atoms have been obtained by monitoring the products with vacuum ultraviolet (VUV) laser induced fluorescence. Translational-to-vibrational (T→V) transfer is dominated by the dynamics of collisions occurring in the two wells on the H+CO potential energy surface, one characterizing the HCO radical and the other characterizing COH. The measured vibrational distributions agree well with the results of trajectory calculations performed on the ab initio potential energy surface of Bowman, Bittman, and Harding (BBH). The measured rotational distributions show two significant differences from the calculated ones. First, for v=0 the experiments find more population in Jwells, but inside the van der Waals well. Second, for v=1, the experimental distribution is flat from J=0 to J=10, whereas the calculated one rises from near zero at J=0 to a peak at J=12. This discrepancy appears to be the result of an excessively high ab initio estimate (by a few tenths of an eV) of the barrier for H atoms addition to CO to form COH
Farm Level Comparison of H.R. 2646 and S. 1731
The provisions in the House (H.R. 2646) and Senate (S. 1731) farm bills are analyzed with respect to their impacts on 94 representative crop, livestock, and dairy farms. The analysis incorporates both historical price and production risk for the farms so the “safety net” aspects of the bills can be compared. Representative crop livestock and dairy farms for major production regions across the county are analyzed. Information to describe and simulate these farms comes from a panel of farmers in each local area. The farm panels are reconvened frequently to update their farm’s data. The representative farm data base has been used for policy analysis for more than 15 years. The simulation model used for the analysis was developed by AFPC scientists.Agribusiness, Agricultural and Food Policy,
q-AQUA: a many-body CCSD(T) water potential, including 4-body interactions, demonstrates the quantum nature of water from clusters to the liquid phase
Many model potential energy surfaces (PESs) have been reported for water;
however, none are strictly from "first principles". Here we report such a
potential, based on a many-body representation at the CCSD(T) level of theory
up to the ultimate 4-body interaction. The new PES is benchmarked for the
isomers of the water hexamer for dissociation energies, harmonic frequencies,
and unrestricted diffusion Monte Carlo (DMC) calculations of the zero-point
energies of the Prism, Book, and Cage isomers. Dissociation energies of several
isomers of the 20-mer agree well with recent benchmark energies. Exploratory
DMC calculations on this cluster verify the robustness of the new PES for
quantum simulations. The accuracy and speed of the new PES are demonstrated for
standard condensed phase properties, i.e., the radial distribution function and
the self-diffusion constant. Quantum effects are shown to be substantial for
these observables and also needed to bring theory into an excellent agreement
with experiment
Descriptive Analysis of a Baseline Concussion Battery Among U.S. Service Academy Members: Results from the Concussion Assessment, Research, and Education (CARE) Consortium
Introduction
The prevalence and possible long-term consequences of concussion remain an increasing concern to the U.S. military, particularly as it pertains to maintaining a medically ready force. Baseline testing is being used both in the civilian and military domains to assess concussion injury and recovery. Accurate interpretation of these baseline assessments requires one to consider other influencing factors not related to concussion. To date, there is limited understanding, especially within the military, of what factors influence normative test performance. Given the significant physical and mental demands placed on service academy members (SAM), and their relatively high risk for concussion, it is important to describe demographics and normative profile of SAMs. Furthermore, the absence of available baseline normative data on female and non-varsity SAMs makes interpretation of post-injury assessments challenging. Understanding how individuals perform at baseline, given their unique individual characteristics (e.g., concussion history, sex, competition level), will inform post-concussion assessment and management. Thus, the primary aim of this manuscript is to characterize the SAM population and determine normative values on a concussion baseline testing battery.
Materials and Methods
All data were collected as part of the Concussion Assessment, Research and Education (CARE) Consortium. The baseline test battery included a post-concussion symptom checklist (Sport Concussion Assessment Tool (SCAT), psychological health screening inventory (Brief Symptom Inventory (BSI-18) and neurocognitive evaluation (ImPACT), Balance Error Scoring System (BESS), and Standardized Assessment of Concussion (SAC). Linear regression models were used to examine differences across sexes, competition levels, and varsity contact levels while controlling for academy, freshman status, race, and previous concussion. Zero inflated negative binomial models estimated symptom scores due to the high frequency of zero scores.
Results
Significant, but small, sex effects were observed on the ImPACT visual memory task. While, females performed worse than males (p < 0.0001, pη2 = 0.01), these differences were small and not larger than the effects of the covariates. A similar pattern was observed for competition level on the SAC. There was a small, but significant difference across competition level. SAMs participating in varsity athletics did significantly worse on the SAC compared to SAMs participating in club or intramural athletics (all p’s < 0.001, η2 = 0.01). When examining symptom reporting, males were more than two times as likely to report zero symptoms on the SCAT or BSI-18. Intramural SAMs had the highest number of symptoms and severity compared to varsity SAMs (p < 0.0001, Cohen’s d < 0.2). Contact level was not associated with SCAT or BSI-18 symptoms among varsity SAMs. Notably, the significant differences across competition level on SCAT and BSI-18 were sub-clinical and had small effect sizes.
Conclusion
The current analyses provide the first baseline concussion battery normative data among SAMs. While statistically significant differences may be observed on baseline tests, the effect sizes for competition and contact levels are very small, indicating that differences are likely not clinically meaningful at baseline. Identifying baseline differences and significant covariates is important for future concussion-related analyses to inform concussion evaluations for all athlete levels
Association of Blood Biomarkers With Acute Sport-Related Concussion in Collegiate Athletes: Findings From the NCAA and Department of Defense CARE Consortium
Importance:
There is potential scientific and clinical value in validation of objective biomarkers for sport-related concussion (SRC).
Objective:
To investigate the association of acute-phase blood biomarker levels with SRC in collegiate athletes.
Design, Setting, and Participants:
This multicenter, prospective, case-control study was conducted by the National Collegiate Athletic Association (NCAA) and the US Department of Defense Concussion Assessment, Research, and Education (CARE) Consortium from February 20, 2015, to May 31, 2018, at 6 CARE Advanced Research Core sites. A total of 504 collegiate athletes with concussion, contact sport control athletes, and non-contact sport control athletes completed clinical testing and blood collection at preseason baseline, the acute postinjury period, 24 to 48 hours after injury, the point of reporting being asymptomatic, and 7 days after return to play. Data analysis was conducted from March 1 to November 30, 2019.
Main Outcomes and Measures:
Glial fibrillary acidic protein (GFAP), ubiquitin C-terminal hydrolase-L1 (UCH-L1), neurofilament light chain, and tau were quantified using the Quanterix Simoa multiplex assay. Clinical outcome measures included the Sport Concussion Assessment Tool-Third Edition (SCAT-3) symptom evaluation, Standardized Assessment of Concussion, Balance Error Scoring System, and Brief Symptom Inventory 18.
Results:
A total of 264 athletes with concussion (mean [SD] age, 19.08 [1.24] years; 211 [79.9%] male), 138 contact sport controls (mean [SD] age, 19.03 [1.27] years; 107 [77.5%] male), and 102 non-contact sport controls (mean [SD] age, 19.39 [1.25] years; 82 [80.4%] male) were included in the study. Athletes with concussion had significant elevation in GFAP (mean difference, 0.430 pg/mL; 95% CI, 0.339-0.521 pg/mL; P < .001), UCH-L1 (mean difference, 0.449 pg/mL; 95% CI, 0.167-0.732 pg/mL; P < .001), and tau levels (mean difference, 0.221 pg/mL; 95% CI, 0.046-0.396 pg/mL; P = .004) at the acute postinjury time point compared with preseason baseline. Longitudinally, a significant interaction (group × visit) was found for GFAP (F7,1507.36 = 16.18, P < .001), UCH-L1 (F7,1153.09 = 5.71, P < .001), and tau (F7,1480.55 = 6.81, P < .001); the interaction for neurofilament light chain was not significant (F7,1506.90 = 1.33, P = .23). The area under the curve for the combination of GFAP and UCH-L1 in differentiating athletes with concussion from contact sport controls at the acute postinjury period was 0.71 (95% CI, 0.64-0.78; P < .001); the acute postinjury area under the curve for all 4 biomarkers combined was 0.72 (95% CI, 0.65-0.79; P < .001). Beyond SCAT-3 symptom score, GFAP at the acute postinjury time point was associated with the classification of athletes with concussion from contact controls (β = 12.298; 95% CI, 2.776-54.481; P = .001) and non-contact sport controls (β = 5.438; 95% CI, 1.676-17.645; P = .005). Athletes with concussion with loss of consciousness or posttraumatic amnesia had significantly higher levels of GFAP than athletes with concussion with neither loss of consciousness nor posttraumatic amnesia at the acute postinjury time point (mean difference, 0.583 pg/mL; 95% CI, 0.369-0.797 pg/mL; P < .001).
Conclusions and Relevance:
The results suggest that blood biomarkers can be used as research tools to inform the underlying pathophysiological mechanism of concussion and provide additional support for future studies to optimize and validate biomarkers for potential clinical use in SRC
Permeation of CO2 and N2 through glassy poly(dimethyl phenylene) oxide under steady- and presteady-state conditions
Glassy polymers are often used for gas separations because of their high selectivity. Although the dual-mode permeation model correctly fits their sorption and permeation isotherms, its physical interpretation is disputed, and it does not describe permeation far from steady state, a condition expected when separations involve intermittent renewable energy sources. To develop a more comprehensive permeation model, we combine experiment, molecular dynamics, and multiscale reaction–diffusion modeling to characterize the time-dependent permeation of N2 and CO2 through a glassy poly(dimethyl phenylene oxide) membrane, a model system. Simulations of experimental time-dependent permeation data for both gases in the presteady-state and steady-state regimes show that both single- and dual-mode reaction–diffusion models reproduce the experimental observations, and that sorbed gas concentrations lag the external pressure rise. The results point to environment-sensitive diffusion coefficients as a vital characteristic of transport in glassy polymers
Nanoscale structural and chemical analysis of F-implanted enhancement-mode InAlN/GaN heterostructure field effect transistors
We investigate the impact of a fluorine plasma treatment used to obtain enhancement-mode operation on the structure and chemistry at the nanometer and atomic scales of an InAlN/GaN field effect transistor. The fluorine plasma treatment is successful in that enhancement mode operation is achieved with a +2.8 V threshold voltage. However, the InAlN barrier layers are observed to have been damaged by the fluorine treatment with their thickness being reduced by up to 50%. The treatment also led to oxygen incorporation within the InAlN barrier layers. Furthermore, even in the as-grown structure, Ga was unintentionally incorporated during the growth of the InAlN barrier. The impact of both the reduced barrier thickness and the incorporated Ga within the barrier on the transistor properties has been evaluated theoretically and compared to the experimentally determined two-dimensional electron gas density and threshold voltage of the transistor. For devices without fluorine treatment, the two-dimensional electron gas density is better predicted if the quaternary nature of the barrier is taken into account. For the fluorine treated device, not only the changes to the barrier layer thickness and composition, but also the fluorine doping needs to be considered to predict device performance. These studies reveal the factors influencing the performance of these specific transistor structures and highlight the strengths of the applied nanoscale characterisation techniques in revealing information relevant to device performance.</jats:p
A cohort study to identify and evaluate concussion risk factors across multiple injury settings: findings from the CARE Consortium
BACKGROUND:
Concussion, or mild traumatic brain injury, is a major public health concern affecting 42 million individuals globally each year. However, little is known regarding concussion risk factors across all concussion settings as most concussion research has focused on only sport-related or military-related concussive injuries.
METHODS:
The current study is part of the Concussion, Assessment, Research, and Education (CARE) Consortium, a multi-site investigation on the natural history of concussion. Cadets at three participating service academies completed annual baseline assessments, which included demographics, medical history, and concussion history, along with the Sport Concussion Assessment Tool (SCAT) symptom checklist and Brief Symptom Inventory (BSI-18). Clinical and research staff recorded the date and injury setting at time of concussion. Generalized mixed models estimated concussion risk with service academy as a random effect. Since concussion was a rare event, the odds ratios were assumed to approximate relative risk.
RESULTS:
Beginning in 2014, 10,604 (n = 2421, 22.83% female) cadets enrolled over 3 years. A total of 738 (6.96%) cadets experienced a concussion, 301 (2.84%) concussed cadets were female. Female sex and previous concussion were the most consistent estimators of concussion risk across all concussion settings. Compared to males, females had 2.02 (95% CI: 1.70-2.40) times the risk of a concussion regardless of injury setting, and greater relative risk when the concussion occurred during sport (Odds Ratio (OR): 1.38 95% CI: 1.07-1.78). Previous concussion was associated with 1.98 (95% CI: 1.65-2.37) times increased risk for any incident concussion, and the magnitude was relatively stable across all concussion settings (OR: 1.73 to 2.01). Freshman status was also associated with increased overall concussion risk, but was driven by increased risk for academy training-related concussions (OR: 8.17 95% CI: 5.87-11.37). Medical history of headaches in the past 3 months, diagnosed ADD/ADHD, and BSI-18 Somatization symptoms increased overall concussion risk.
CONCLUSIONS:
Various demographic and medical history factors are associated with increased concussion risk. While certain factors (e.g. sex and previous concussion) are consistently associated with increased concussion risk, regardless of concussion injury setting, other factors significantly influence concussion risk within specific injury settings. Further research is required to determine whether these risk factors may aid in concussion risk reduction or prevention
Pulsating hydrogen-deficient white dwarfs and pre-white dwarfs observed with TESS : III. Asteroseismology of the DBV star GD 358
Context. The collection of high-quality photometric data by space telescopes, such as the completed Kepler mission and the ongoing TESS program, is revolutionizing the area of white-dwarf asteroseismology. Among the different kinds of pulsating white dwarfs, there are those that have He-rich atmospheres, and they are called DBVs or V777 Her variable stars. The archetype of these pulsating white dwarfs, GD 358, is the focus of the present paper. Aims. We report a thorough asteroseismological analysis of the DBV star GD 358 (TIC 219074038) based on new high-precision photometric data gathered by the TESS space mission combined with data taken from the Earth. Methods. We reduced TESS observations of the DBV star GD 358 and performed a detailed asteroseismological analysis using fully evolutionary DB white-dwarf models computed accounting for the complete prior evolution of their progenitors. We assessed the mass of this star by comparing the measured mean period separation with the theoretical averaged period spacings of the models, and we used the observed individual periods to look for a seismological stellar model. We detected potential frequency multiplets for GD 358, which we used to identify the harmonic degree (`) of the pulsation modes and rotation period. Results. In total, we detected 26 periodicities from the TESS light curve of this DBV star using standard pre-whitening. The oscillation frequencies are associated with nonradial g(gravity)-mode pulsations with periods from ∼422 s to ∼1087 s. Moreover, we detected eight combination frequencies between ∼543 s and ∼295 s. We combined these data with a huge amount of observations from the ground. We found a constant period spacing of 39.25 ± 0.17 s, which helped us to infer its mass (M? = 0.588 ± 0.024 M ) and constrain the harmonic degree ` of the modes. We carried out a period-fit analysis on GD 358, and we were successful in finding an asteroseismological model with a stellar mass (M? = 0.584+0.025 −0.019 M ), compatible with the stellar mass derived from the period spacing, and in line with the spectroscopic mass (M? = 0.560 ± 0.028M ). In agreement with previous works, we found that the frequency splittings vary according to the radial order of the modes, suggesting differential rotation. Obtaining a seismological model made it possible to estimate the seismological distance (dseis = 42.85 ± 0.73 pc) of GD 358, which is in very good accordance with the precise astrometric distance measured by Gaia EDR3 (π = 23.244 ± 0.024, dGaia = 43.02 ± 0.04 pc). Conclusions. The high-quality data measured with the TESS space telescope, used in combination with data taken from ground-based observatories, provides invaluable information for conducting asteroseismological studies of DBV stars, analogously to what happens with other types of pulsating white-dwarf stars. The currently operating TESS mission, together with the advent of other similar space missions and new stellar surveys, will give an unprecedented boost to white dwarf asteroseismology
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