Successful Pathways to Undergraduate Completion

This article explores the critical factors that led to successful college completion for Black men. By focusing on success factors from Black male college graduates\u27 lived experiences, a roadmap to college success for this group may be shared with others to encourage increased degree attainment for this population. The lens for this study drew from Harper’s (2012) antideficit theory, which highlights students’ successes rather than problematic issues. A non-random approach of purposeful sampling from eight Black men from LinkedIn who had completed an undergraduate degree from a private, predominately White college in the southeast United States defined the sample size. Using one-on-one interviews, participants\u27 internal and external experiences leading up to and through college were revealed. The study will address their academic success in achieving undergraduate degree attainment. The first two categories, pre-college socialization and readiness and college achievement are the focus of this study

Constraints: An Integrated Viewpoint

The theory of constraints has been researched in both leisure studies and motor behavior within kinesiology. Constraints are limitations or barriers imposed on the individual that may lead to decreased or non-participation in an activity. Findings have led to the formulation of several frameworks in order to direct the research surrounding constraints. The purpose of this paper is to outline the frameworks as designed by Crawford and colleagues KEY WORDS: Constraints, motor behavior, leisure The field of health and human performance has significantly contributed to our understanding of factors that affect the human body in all domains: physical, affective, cognitive, spiritual, and social. Human beings are complex systems. The human body is similar to that of a computer whereby information is taken in from the environment, processed by the brain, and displayed by actions as output. The goal of this output is known as goal directed behavior. The academic field of motor behavior focuses on how goal directed movements originates, how the movement patterns change, and how they persist throughout the life span. Researchers in other related fields, such as recreation and leisure studies, have focused research on such topics including: recreation participation, motives, preferences, and satisfaction. Researchers and practitioners in both disciplines strive to attain a common goal: increased quality of life for an individual. What are the factors that contribute or impede on an individual's attainment of quality of life? An area of research that has gained considerable attention among researchers across disciplines is constraints. On a general level, constraints are those factors that may limit participation and enjoyment in a given activity Researchers within the field of motor behavior have posed an interest in studying constraints. Movement is essentially the way in which one interacts with the environment, and by understanding movement; individuals within therapeutic and educational settings may begin to better understand such things as skillfulnes

Speed and Rhythm Affect Temporal Structure of Variability in Reaching Poststroke: A Pilot Study

Temporal structure reveals the potential adaptive strategies employed during upper extremity movements. The authors compared the temporal structure of upper extremity joints under 3 different reaching conditions: preferred speed, fast speed, and reaching with rhythmic auditory cues in 10 individuals poststroke. They also investigated the temporal structure of these 3 reaching conditions in 8 healthy controls to aid in the interpretation of the observed patterns in the poststroke cohort. Approximate entropy (ApEn) was used to measure the temporal structure of the upper extremity joints. ApEn was similar between conditions in controls. After stroke, ApEn was significantly higher for shoulder, elbow, and wrist both at fast speed and with rhythmic cues compared with preferred speed. ApEn at index finger was significantly higher only with rhythmic cues compared with preferred speed. The authors propose that practice reaching at faster speed and with rhythmic cues as a component of rehabilitation interventions may enhance adaptability after stroke

Temporal structure of variability decreases in upper extremity movements post stroke

Methods: Sixteen participants with chronic stroke and nine age-matched controls performed three trials of functional reach-to-grasp. The amount of variability was quantified by computing the standard deviation of shoulder, elbow, wrist and index finger flexion/extension joint angles. The temporal structure of variability was determined by calculating approximate entropy in shoulder, elbow, wrist and index finger flexion/extension joint angles. Findings: Individuals with stroke demonstrated greater standard deviations and significantly reduced approximate entropy values as compared to controls. Furthermore, motor impairments and kinematics demonstrated moderate to strong correlations with temporal structure of variability. Interpretation: Changes in the temporal structure of variability in upper-extremity joint angles suggest that movement patterns used by stroke survivors are less adaptable. This knowledge may yield additional insights into the impaired motor system and suggest better interventions that can enhance upper-extremity movement adaptability

Every mapping class group is generated by 6 involutions

Let Mod_{g,b} denote the mapping class group of a surface of genus g with b punctures. Feng Luo asked in a recent preprint if there is a universal upper bound, independent of genus, for the number of torsion elements needed to generate Mod_{g,b}. We answer Luo's question by proving that 3 torsion elements suffice to generate Mod_{g,0}. We also prove the more delicate result that there is an upper bound, independent of genus, not only for the number of torsion elements needed to generate Mod_{g,b} but also for the order of those elements. In particular, our main result is that 6 involutions (i.e. orientation-preserving diffeomorphisms of order two) suffice to generate Mod_{g,b} for every genus g >= 3, b = 0, and g >= 4, b = 1.Comment: 15 pages, 7 figures; slightly improved main result; minor revisions. to appear in J. Al

Feasibility of Electromyography-Triggered Neuromuscular Stimulation as an Adjunct to Constraint-Induced Movement Therapy

Background and Purpose. The purpose of this case report is to explore the feasibility of electromyography-triggered neuromuscular stimulation (EMG-stim) as an adjunct to constraint-induced movement therapy (CIMT). Case Description. The patient was a 72-year-old man, 10 years poststroke, who did not meet traditional CIMT criteria. The EMG-stim was applied to the wrist extensors of the patient\u27s weaker arm for one half of the CIMT training hours. Outcomes. The intervention was feasible for this individual. Improvements were observed in motor behavior, quality and amount of use, muscle activity, wrist range of motion, and reaction time of the more-affected extremity. These improvements were paralleled by a change in the size and location of the extensor digitorum communis muscle representation in the primary motor cortex, as measured by transcranial magnetic stimulation mapping. Discussion. These changes suggest that using EMG-stim as an adjunct to CIMT should be further investigated in individuals who have low functional abilities following stroke

Reduction of freezing of gait in Parkinson's disease by repetitive robot-assisted treadmill training: a pilot study

<p>Abstract</p> <p>Background</p> <p>Parkinson's disease is a chronic, neurodegenerative disease characterized by gait abnormalities. Freezing of gait (FOG), an episodic inability to generate effective stepping, is reported as one of the most disabling and distressing parkinsonian symptoms. While there are no specific therapies to treat FOG, some external physical cues may alleviate these types of motor disruptions. The purpose of this study was to examine the potential effect of continuous physical cueing using robot-assisted sensorimotor gait training on reducing FOG episodes and improving gait.</p> <p>Methods</p> <p>Four individuals with Parkinson's disease and FOG symptoms received ten 30-minute sessions of robot-assisted gait training (Lokomat) to facilitate repetitive, rhythmic, and alternating bilateral lower extremity movements. Outcomes included the FOG-Questionnaire, a clinician-rated video FOG score, spatiotemporal measures of gait, and the Parkinson's Disease Questionnaire-39 quality of life measure.</p> <p>Results</p> <p>All participants showed a reduction in FOG both by self-report and clinician-rated scoring upon completion of training. Improvements were also observed in gait velocity, stride length, rhythmicity, and coordination.</p> <p>Conclusions</p> <p>This pilot study suggests that robot-assisted gait training may be a feasible and effective method of reducing FOG and improving gait. Videotaped scoring of FOG has the potential advantage of providing additional data to complement FOG self-report.</p

A Systematic Mapping Approach of 16q12.2/FTO and BMI in More Than 20,000 African Americans Narrows in on the Underlying Functional Variation: Results from the Population Architecture using Genomics and Epidemiology (PAGE) Study

Genetic variants in intron 1 of the fat mass- and obesity-associated (FTO) gene have been consistently associated with body mass index (BMI) in Europeans. However, follow-up studies in African Americans (AA) have shown no support for some of the most consistently BMI-associated FTO index single nucleotide polymorphisms (SNPs). This is most likely explained by different race-specific linkage disequilibrium (LD) patterns and lower correlation overall in AA, which provides the opportunity to fine-map this region and narrow in on the functional variant. To comprehensively explore the 16q12.2/FTO locus and to search for second independent signals in the broader region, we fine-mapped a 646-kb region, encompassing the large FTO gene and the flanking gene RPGRIP1L by investigating a total of 3,756 variants (1,529 genotyped and 2,227 imputed variants) in 20,488 AAs across five studies. We observed associations between BMI and variants in the known FTO intron 1 locus: the SNP with the most significant p-value, rs56137030 (8.3×10-6) had not been highlighted in previous studies. While rs56137030was correlated at r2>0.5 with 103 SNPs in Europeans (including the GWAS index SNPs), this number was reduced to 28 SNPs in AA. Among rs56137030 and the 28 correlated SNPs, six were located within candidate intronic regulatory elements, including rs1421085, for which we predicted allele-specific binding affinity for the transcription factor CUX1, which has recently been implicated in the regulation of FTO. We did not find strong evidence for a second independent signal in the broader region. In summary, this large fine-mapping study in AA has substantially reduced the number of common alleles that are likely to be functional candidates of the known FTO locus. Importantly our study demonstrated that comprehensive fine-mapping in AA provides a powerful approach to narrow in on the functional candidate(s) underlying the initial GWAS findings in European populations

Exposure to ambient particulate matter is associated with accelerated functional decline in idiopathic pulmonary fibrosis

BACKGROUND: Idiopathic pulmonary fibrosis (IPF), a progressive disease with an unknown pathogenesis, may be due in part to an abnormal response to injurious stimuli by alveolar epithelial cells. Air pollution and particulate inhalation of matter evoke a wide variety of pulmonary and systemic inflammatory diseases. We therefore hypothesized that increased average ambient particulate matter (PM) concentrations would be associated with an accelerated rate of decline in FVC in IPF. METHODS: We identified a cohort of subjects seen at a single university referral center from 2007 to 2013. Average concentrations of particulate matter < 10 and < 2.5 μg/m3 (PM10 and PM2.5, respectively) were assigned to each patient based on geocoded residential addresses. A linear multivariable mixed-effects model determined the association between the rate of decline in FVC and average PM concentration, controlling for baseline FVC at first measurement and other covariates. RESULTS: One hundred thirty-five subjects were included in the final analysis after exclusion of subjects missing repeated spirometry measurements and those for whom exposure data were not available. There was a significant association between PM10 levels and the rate of decline in FVC during the study period, with each μg/m3 increase in PM10 corresponding with an additional 46 cc/y decline in FVC (P = .008). CONCLUSIONS: Ambient air pollution, as measured by average PM10 concentration, is associated with an increase in the rate of decline of FVC in IPF, suggesting a potential mechanistic role for air pollution in the progression of disease