It Takes a Lot of Lights to Make a City

“It Takes a Lot of Lights to Make a City” is a collection of short stories set in Halifax, Nova Scotia between 2010 and 2017, a period during which the city, long reliant on its heritage as the basis of its cultural identity, experienced a rapid shift toward modernization and urbanization. The characters of “It Takes a Lot of Light” experience forms of psychic displacement in response to the city’s socioeconomic transformation. These characters, including an unemployed university dropout, a social-climbing landscaper, and a middle-aged professional stifled by her retired husband, form a community of disparate individuals affected directly or indirectly by Halifax’s shifting economic landscape. This community is reflected in the structural approach to the short story collection; The six stories that comprise “It Takes a Lot of Lights” operate both individually, and as components of a larger unified work, linked by geography, character, and a recurrent focus on class disparity. This approach to the short story collection aims to explore the genre’s potential to function as a network of individual stories whose thematic context is transformed and expanded via their relationships with one another

The implementation of a radiographic reporting service for trauma examinations of the skeletal system in 4 NHS trusts. NHS Executive South Thames funded research project

Executive Summary The implementation of a Radiographic Reporting Service for trauma examinations of the skeletal system, in 4 National Health Service Trusts Project Reference: SPGS 438 Project Dates: 1 September 1997 (project start) 30 November 1998 (project end) 31 March 1999: Date of report submission Project Leader: Mr Keith Piper, Senior Lecturer and Programme Director, PgD Clinical Reporting * Research Assistant: Ms Carol Ryan, Department of Radiography * Project Supervisor: Mrs Audrey Paterson, Dean of Faculty of Health and Sciences and Head of Department of Radiography * * Canterbury Christ Church University College Main Research Objectives The purpose of the study was to evaluate the implementation of a Radiographic Reporting Service (RRS) in four NHS Trusts in the United Kingdom with specific reference to the reporting by radiographers of musculo-skeletal trauma examinations. The research investigated the accuracy of radiographers’ written reports in terms of sensitivity and specificity; the impact on patient care and management as measured by the volume of reporting activity undertaken and the speed with which reports became available; costs related to the implementation of an RRR, and satisfaction of the users of the service. Methodology and Sample Size A longitudinal study design was used to measure the productivity and effectiveness of radiographic reporting in four NHS Trusts and five clinical sites in England. Data were collected by direct measure, report pro-forma, semi-structured questionnaires and interviews. A series of base line measurements were made at the commencement of the project. These were the volume of reporting activity prior to implementation of an RRS and the speed with which the reports became available. The satisfaction of the users of the reporting service prior to the implementation of an RRS was also gauged. Three measures (volume, speed, satisfaction of users) were repeated after the RRS had been implemented. Longitudinal data on the accuracy of the radiographers’ reports in terms of sensitivity and specificity were also collected at each site. Finally, some cost information related to the introduction and provision of an RRS was gathered. Four NHS Trusts and 10 radiographers participated in the study. Radiographers completed 10275 reports and 7179 were used to assess accuracy, sensitivity and specificity. Volume and speed data were obtained from the normal workload in each Trust. Four radiology services managers provided the cost data, while 26 staff took part in the initial survey and 12 in the final survey. Problems The major problem with this study was the fact that it was investigating the implementation into practice of a new and controversial service. It was beset, therefore, with the difficulties of aligning a research project to practice and this was only possible imperfectly. Points of implementation of the new service varied considerably, workload of key staff made verification of reports difficult and information systems within Trusts proved problematic. Findings Radiographers’ reports were accurate and consistently so over time. Significant improvements in the volume of reporting activity were found post-implementation at 2 of the 4 clinical sites in which this was measured. Additionally, the speed with which reports became available was shown to have improved significantly in all 4 NHS Trusts (but not at one clinical site). Cost data was not considered to be reliable and more evaluation of costs is required. Users of the radiographic reporting services were extremely or very satisfied with the quality of reports produced by the radiographers and also satisfied with the nature of the service implemented. Finally, a range of organisational issues were seen to affect the implementation of these services, at times quite inappropriately. Conclusion NHS Trusts that are unable to provide a full and/or timely musculo-skeletal trauma reporting service should implement a radiographic reporting service but must ensure that this is properly planned, funded, implemented and managed. Monitoring of service effectiveness and auditing of reporting standards should take place periodically. Acknowledgements The four collaborating NHS Trusts and their staff; Expert panel members; Members of the Steering Group; Colleagues at Canterbury Christ Church University College, and the Research and Development Directorate at South Thames Regional Office (NHSE)

Actinobaculum schaalii: An Emerging Uropathogen?

A. schaalii is a rare uropathogen. We report urosepsis with Actinobaculum schaalii detected serendipitously in blood and urine culture in a 79-year-old with urinary tract obstruction. This paper illuminates the flaws in our current system in detecting A. schaalii and raises awareness among clinicians and laboratory teams

09311 Abstracts Collection -- Classical and Quantum Information Assurance Foundations and Practice

From 26 July 2009 to 31 July 2009, the Dagstuhl Seminar 09311 ``Classical and Quantum Information Assurance Foundations and Practice\u27\u27 was held in Schloss Dagstuhl~--~Leibniz Center for Informatics. The workshop was intended to explore the latest developments and discuss the open issues in the theory and practice of classical and quantum information assurance. A further goal of the workshop was to bring together practitioners from both the classical and the quantum information assurance communities. To date, with a few exceptions, these two communities seem to have existed largely separately and in a state of mutual ignorance. It is clear however that there is great potential for synergy and cross-fertilization between and this we sought to stimulate and facilitate

Quantification of plaque stiffness by Brillouin microscopy in experimental thin cap fibroatheroma

Plaques vulnerable to rupture are characterized by a thin and stiff fibrous cap overlaying a soft lipid-rich necrotic core. The ability to measure local plaque stiffness directly to quantify plaque stress and predict rupture potential would be very attractive, but no current technology does so. This study seeks to validate the use of Brillouin microscopy to measure the Brillouin frequency shift, which is related to stiffness, within vulnerable plaques. The left carotid artery of an ApoE-/- mouse was instrumented with a cuff that induced vulnerable plaque development in nine weeks. Adjacent histological sections from the instrumented and control arteries were stained for either lipids or collagen content, or imaged with confocal Brillouin microscopy. Mean Brillouin frequency shift was 15.79±0.09 GHz in the plaque compared with 16.24±0.15 (p \u3c 0.002) and 17.16±0.56 GHz (p \u3c 0.002) in the media of the diseased and control vessel sections, respectively. In addition, frequency shift exhibited a strong inverse correlation with lipid area of 20.67±0.06 (p \u3c 0.01) and strong direct correlation with collagen area of 0.71±0.15 (p \u3c 0.05). This is the first study, to the best of our knowledge, to apply Brillouin spectroscopy to quantify atherosclerotic plaque stiffness, which motivates combining this technology with intravascular imaging to improve detection of vulnerable plaques in patients

Megapixel imaging of (micro)nutrients in mature barley grains

Understanding the accumulation and distribution of essential nutrients in cereals is of primary importance for improving the nutritional quality of this staple food. While recent studies have improved the understanding of micronutrient loading into the barley grain, a detailed characterization of the distribution of micronutrients within the grain is still lacking. High-definition synchrotron X-ray fluorescence was used to investigate the distribution and association of essential elements in barley grain at the micro scale. Micronutrient distribution within the scutellum and the embryo was shown to be highly variable between elements in relation to various morphological features. In the rest of the grain, the distribution of some elements such as Cu and Zn was not limited to the aleurone layer but extended into the endosperm. This pattern of distribution was less marked in the case of Fe and, in particular, Mn. A significant difference in element distribution was also found between the ventral and dorsal part of the grains. The correlation between the elements was not consistent between and within tissues, indicating that the transport and storage of elements is highly regulated. The complexity of the spatial distribution and associations has important implications for improving the nutritional content of cereal crops such as barley

Biochemical mutagens affect the preservation of fungi and biodiversity estimations

Many fungi have significant industrial applications or biosafety concerns and maintaining the original characteristics is essential. The preserved fungi have to represent the situation in nature for posterity, biodiversity estimations, and taxonomic research. However, spontaneous fungal mutations and secondary metabolites affecting producing fungi are well known. There is increasing interest in the preservation of microbes in Biological Resource Centers (BRC) to ensure that the organisms remain viable and stable genetically. It would be anathema if they contacted mutagens routinely. However, for the purpose of this discussion, there are three potential sources of biochemical mutagens when obtaining individual fungi from the environment: (a) mixtures of microorganisms are plated routinely onto growth media containing mutagenic antibiotics to control overgrowth by contaminants, (b) the microbial mixtures may contain microorganisms capable of producing mutagenic secondary metabolites, and (c) target fungi for isolation may produce “self” mutagens in pure culture. The probability that these compounds could interact with fungi undermines confidence in the preservation process and the potential effects of these biochemical mutagens are considered for the first time on strains held in BRC in this review