857 research outputs found
Intertextualidad de arte y vida en obras recientes de Clara Janés: una perspectiva femenina
La conocida poeta española Clara JanĂ©s, autora de más de 30 libros de poesĂa, muchos de ellos ya traducidos a varias lenguas, siempre ha cultivado un enfoque estĂ©tico que cruza fronteras entre arte y vida, integrando una con la otra para crear una totalidad intertextual coherente de mĂşltiples y diversas formas artĂsticas. Propongo aquĂ enfocar en tres de sus obras recientes todavĂa menos conocidas, La indetenible quietud (versiĂłn revisada, 2008), Peregrinaje (2010) y, por Ăşltimo, Psi o el jardĂn de las delicias (2014), en donde JanĂ©s entreteje sus meditaciones literarias y filosĂłficas en armonĂa con expresiones artĂsticas variadas. En la primera, pondera sus reflexiones en torno a la obra del famoso escultor vasco Eduardo Chillida, en la segunda se vuelve atrás para examinar un texto original (Toscana) de su musa más importante, Vladimir Holan, a la vez que se basa en imágenes de pintura clásica, y en la más reciente (Psi), explora sus propias experiencias mĂsticas-espirituales en relaciĂłn con teorĂas de la fĂsica cuántica. TambiĂ©n de paso harĂ© referencia a los efectos de la mĂşsica en Kampa y los de la fĂsica en Variables ocultas y Orbes del sueño. En el conjunto de su poesĂa, crea JanĂ©s un solo intertexto enorme sacado de diferentes medios de expresiĂłn artĂstica, reflejando su visiĂłn poĂ©tica que todo en la vida es arte y que el arte se convierte en vida, en una forma más tĂpicamente femenina que masculin
Constitutional Law - Standing - Taxpayer\u27s Standing Limited to Congressional Actions Authorized by the Taxing and Spending Power - Valley Forge Christian College v. Americans United for Separation of Church and State Inc., 102 S. Ct. 752 (1982).
A Priestly Profile of the First Navy Chaplain to Receive the Medal of Honor
This tribute to Father Joseph O\u27Callahan, S.J. profiles the family upbringing and religious training of the Jesuit priest who served as a chaplain in the United States Navy and later as a professor at the College of the Holy Cross. It also recounts Fr. O\u27Callahan\u27s heroic efforts in the aftermath of an attack on the USS Franklin during World War II. He was later awarded the Congressional Medal of Honor, the first chaplain of the armed forces to ever receive the nation\u27s highest honor
Immunoparalysis in Septic Shock Patients
In the recent years, it has become clear that septic shock is characterized by the simultaneous production of inflammatory and anti-inflammatory mediators; the primary role of the latter is to counterbalance the former, thus limiting the severity of their systemic effects. However, in a number of patients, the anti-inflammatory substances can cause a downregulation in both the innate and adaptive immune capabilities, leading a second phase characterized to secondary infections caused by opportunist germs and the reactivation of latent viruses, muscle wasting; altogether, these abnormalities set the stage for a chronic critical condition. This condition, whose identification is relatively recent, is called immunoparalysis. Unfortunately, the current approach to septic shock is focused much more on the inflammatory phase than in the ensuing immunoparalysis, whose diagnosis can be challenging. In this chapter, the role played by both classes of mediators, the monitoring of the immune system, and the possible current and not yet available therapeutic strategies of immunoparalysis are reviewed and discussed
Editor\u27s Introduction
The VA Engage Journal is an annually published scholarly journal promoting reflection and dialogue on the topic of civic engagement by undergraduate, graduate, and professional students at Virginia colleges and universities. The journal acts as a forum for discussion to enhance our collective understanding of the purposes and practices of civic engagement. Students may submit critical reflections on engagement, reviews of current literature, and personal quantitative, qualitative, or mixed-methods research studies for publication. In the fifth volume of the VA Engage Journal, four authors reflect on the different limitations in their communities and the potential for growth through engagement that challenges these limits
Constructing (Dis)ability through participation in early childhood markets: Preschool leaders’ enrolment decision-making
This article employs a critical case study (critical disability studies and critical policy analysis) to unpack how leaders in publicly funded private prekindergarten programs invoke conceptions of normality, and subsequently abnormality, during decision-making processes for student (dis)enrolment. More specifically, this research is concerned with ways private preschool leaders’ constructions of disability are implicated in decision-making affecting student enrolment and disenrollment, thereby facilitating constructions of children’s participation in this state-sanctioned early childhood education program. Three leadership teams at private preschools participated in responsive interviews, observations, and provided policy and curricular documents for analysis. Findings reveal how policy, market, and preschool leaders’ conceptions of (ab)normality influenced decision-making rationales and outcomes affecting (dis)enrolled students. Additionally, findings indicated leaders’ sense of identity impacted their interpretation of and reaction to program polices, local market pressures, and their construction of the “good consumer”—a parent/child dyad prepared for rigor with the exhibition of self-control. This research evinces complexities undergirding leaders’ decision-making when choosing to (dis)enrol students in publicly-funded voucher programs on privately-driven markets and how decisions function to (re)shape (dis)ability discourses in early childhood
EVALUATING SEMANTIC ANALYSIS METHODS FOR SHORT ANSWER GRADING USING LINEAR REGRESSION
The assessment of free-text answers may demand significant human effort, especially in scenarios with many students. This paper focuses on the automatic grading of short answer written in Portuguese language using techniques of natural language processing and semantic analysis. A previous study found that a similarity scoring model might be more suitable to a question type than to another. In this study, we combine latent semantic analysis (LSA) and a WordNet path-based similarity method using linear regression to predict scores for 76 short answers to three questions written by high school students. The predicted scores compared well to human scores and the use of combined similarity scores showed an improvement in overall results in relation to a previous study on the same corpus. The presented approach may be used to support the automatic grading of short answer using supervised machine learning to weight different similarity scoring models.  
Characterizing the Intracellular Distribution of Mutant Thyroid Hormone Receptor α-1 A382PfsX7
Resistance to Thyroid Hormone (RTH) syndrome is a developmental disease characterized by the failure of peripheral tissues to respond to thyroid hormone signaling. A382PfsX7 is a nonfunctional RTH-associated variant of thyroid hormone receptor α1 which fails to bind thyroid hormone and disassociate from corepressors. The mutation also deletes a nuclear export signal (NES) from the C-terminal end of the receptor. This thesis sought to determine whether this NES deletion altered the intracellular distribution of TR in a way which would imply interference with its role in transcriptional activation and repression. Using lipid-based transfection of fluorescently-labeled TR into HeLa (human) cells and fluorescent microscopy, the nuclear-to-cytoplasmic ratio of wild-type (WT) and mutant TR and the presence of TR aggregates was evaluated. Coexpression of WT-TRα1 and A382PfsX7 is associated with a cytosolic shift in localization and an increased frequency of TR aggregation. These data suggest that novel interactions between WT and mutant receptors may increase the aggregation propensity of TR and thereby alter localization
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